ACS Applied Optical Materials
·
2025
·
IF 3.8
Yujiao Jiang,Ziyi Ye,Mengling Yu,Zhengxing Gong,Xinfeng Zhang
With the widespread use of personal electronic devices, excessive blue light exposure that causes retinal cell damage and skin hyperpigmentation has attracted increasing attention. However, an effective indicator for real-time in-house monitoring of blue light is still lacking. In this study, we developed a screen-attachable visual hydrogel indicator for facile in-house monitoring of blue light. The indicator is fabricated by encapsulating both a blue light-responsive photosensitizer (fluorescein) and 3,3′,5,5′-tetramethylbenzidine (TMB) within an agarose hydrogel. Upon exposure to blue light, the photosensitizer generates reactive oxygen species (ROS), which oxidize colorless TMB to blue oxTMB. The proximity of fluorescein and TMB within the hydrogel nanopores significantly facilitates the oxidation reaction. Hence, using a hydrogel as the reaction carrier not only makes the indicator screen-attachable but also greatly enhances its sensitivity. The color change of TMB is good linearly with the blue light doses in the range of 0.15–1.2 J/cm2 with a detection limit about 0.082 J/cm2, much lower than the threshold (0.75 J/cm2) for oxidative eye stress. Green and red light from the electronic products caused no interference for the monitoring of blue light. It was successfully applied for monitoring the cumulative dose of blue light emitted from the three types of electronic products (i.e., laptops, tablets, and light-emitting diode (LED) lamps) by simply attaching the indicator on the screen or on the desk. This hydrogel indicator, with the merits of screen-attach ability, facile use, and high sensitivity, is quite appealing for in-house monitoring of blue light from electronic products.
研究领域:
光学传感
·
材料科学
·
生物医学工程
·
环境监测
✓ 已验证
产品关联
DOI
高影响因子
ELECTROPHORESIS
·
2015
·Vol. 36
·期 20
·2509-2515
·
IF 3.028
Haiyun Zhai,Kaisong Yuan,Xiao Yu,Zuanguang Chen,Zhenping Liu,Zihao Su
A novel fluorescence detection system for CE was described and evaluated. Two miniature laser pointers were used as the excitation source. A Y-style optical fiber was used to transmit the excitation light and a four-branch optical fiber was used to collect the fluorescence. The optical fiber and optical filter were imported into a photomultiplier tube without any extra fixing device. A simplified PDMS detection cell was designed with guide channels through which the optical fibers were easily aligned to the detection window of separation capillary. According to different requirements, laser pointers and different filters were selected by simple switching and replacement. The fluorescence from four different directions was collected at the same detecting point. Thus, the sensitivity was enhanced without peak broadening. The fluorescence detection system was simple, compact, low-cost, and highly sensitive, with its functionality demonstrated by the separation and determination of red dyes and fluorescent whitening agents. The detection limit of rhodamine 6G was 7.7 nM (S/N = 3). The system was further applied to determine illegal food dyes. The CE system is potentially eligible for food safety analysis.
研究领域:
分析化学
·
生物医学工程
·
食品安全
·
分子检测技术
✓ 已验证
DOI
高影响因子
JOURNAL OF FOOD ENGINEERING
·
2023
·
IF 5.5
Beibei Ye,Cikun Liu,Huan Li,Feifei Wang,Jian Chen,Yanbo Wang
The spoilage of seafood is highly dependent on temperature changes during cold chain. To visually reflect the shelf-life of large yellow croakers (0–25 °C), the xylose-lysine based time-temperature indicator (TTI) label was designed and applicated. The ultraviolet (UV) spectrum, and color response of Maillard reaction (MR) indicated that the color changes of TTI was related to the formation of melanoidins of MR. The color changes of TTI, and the quality degradation of large yellow croakers were described by kinetics analysis, which showed that Ea of TVB-N (70.45 kJ/mol) was closer to that of TTI (83.51 kJ/mol). Under fluctuating temperatures, the difference of the effective temperature (T eff ) between TVB-N (15.95 °C) and TTI (16.84 °C) was less than 1 °C, and the relative error of shelf-life was −8.33%. Briefly, this novel TTI label as an environmentally friendly system could be attached to sample surface for real-time reflecting shelf-life of seafood in cold chain.
研究领域:
食品科学
·
生物学
✓ 已验证
产品关联
DOI
高影响因子
Food Chemistry-X
·
2024
·
IF 6.5
Lin Wang,Tianxin Yuan,Yan Zhang
A time-temperature integrator (TTI) based on laccase@Cu 3 (PO4) 2 nanoflowers (laccase@NFs) was created to monitor the freshness of pasteurized milk during storage. To address the challenges of easy inactivation, poor stability, and high use-cost of laccase in the application of TTI, laccase@NFs were synthesized by ultrasonic-assisted biomineralization. The laccase@NFs-based TTI was created through the enzymatic reaction between laccase and 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid ammonium salt), and the effects of laccase@NFs addition amount on the reaction rate, discoloration lifetime and activation energy (Ea) were discussed. Furthermore, the spoilage pattern and kinetic properties of pasteurized milk were explored based on titratable acidity. The measurement of the Ea was determined as 49.98 kJ/mol, and an investigation was conducted to assess the suitability of the TTI with pasteurized milk under both constant and variable temperature conditions. This research aims to contribute valuable insights into the application of enzymatic TTI in monitoring the shelf life of pasteurized milk.
研究领域:
食品科学
·
生物技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Advanced Optical Materials
·
2020
·Vol. 8
·期 23
·2001367
·
IF 8.286
Yong Qi,Changtong Zhou,Wenbin Niu,Shufen Zhang,Suli Wu,Wei Ma,Bingtao Tang
Due to the increasing human mortality caused by natural disasters and traffic accidents, the development of smart traffic warning systems is urgent. The first smart indicator for traffic warning based on bilayer photonic crystals with both selective retroreflection and response reflection optical properties is developed. The wettability-controlled reflection evaluates the risk of landslides and warns drivers to slow down, while the retroreflection simultaneously displays iridescent vivid structural colors to observers at different viewing directions relative to the illumination direction and informs drivers the approaching of the accident blackspot. The mechanism involves diffractions in the periodic nanostructures and uses the wettability of vertical surfaces to realize the spectral diversity of reflectance. Moreover, colorful flickering structural colors based on the rotational periodic diffraction and angle dependence of the retroreflection are designed for speed limits warning. It demonstrates an energy-efficient, smart, and tunable multi-functionalized bilayer photonic crystal that is especially suitable for nighttime traffic warning, advertisement, and periodic warning display applications.
研究领域:
材料科学
·
光学工程
·
智能交通系统
✓ 已验证
DOI
高影响因子
Small
·
2019
·Vol. 15
·期 49
·1903489
·
IF 10.856
Chunyang Zhou,Hongmei Geng,Pengfei Wang,Chunlei Guo
The prospect of programming molecular computing systems to realize complex autonomous tasks has advanced the design of synthetic biochemical logic circuits. One way to implement digital and analog integrated circuits is to use noncovalent hybridization and strand displacement reactions in cell-free and enzyme-free nucleic acid systems. To date, DNA-based circuits involving tens of logic gates capable of implementing basic and complex logic functions have been demonstrated experimentally. However, most of these circuits are still incapable of realizing complex mathematical operations, such as square root logic operations, which can only be carried out with 4 bit binary numbers. A high-capacity DNA biocomputing system is demonstrated through the development of a 10 bit square root logic circuit. It can calculate the square root of a 10 bit binary number (within the decimal integer 900) by designing DNA sequences and programming DNA strand displacement reactions. The input signals are optimized through the output feedback to improve performance in more complex logical operations. This study provides a more universal approach for applications in biotechnology and bioengineering.
研究领域:
合成生物学
·
分子工程
·
生物技术
✓ 已验证
DOI
PubMed
高影响因子
Food and Bioprocess Technology
·
2024
·
IF 5.3
Xu Hailin,Guo Yaru,Zhou Shufang,Wang Jiayi,Lu Futai,Wang Shuo,Deng Qiliang
Time and temperature are the crucial factors affecting the quality of perishable products. The device capable of recording temperature fluctuation and maintaining time has huge practical potential. In this research, a novel thermal history indicator (THI) was proposed based on covalent organic frameworks (COFs) with the irreversible color change performance. The color change and absorbance of the THI were investigated over a broad monitoring temperature range (− 22 ~ 55 ℃) and were closely correlated with its thermal accumulation over time and temperature. The activation energy ( E a ) of the THI was calculated to be 55.31 kJ mol −1 , which can be used to monitor the perishable products with deterioration reaction E a ranging from 30.31 to 80.31 kJ mol −1 . In addition, the THI also demonstrated the significant response to the environmental temperature fluctuations. Furthermore, the potential applications were evaluated by recording the changes of the THI gel and the total viable count (TVC) of food under the same conditions. The results indicated that the digital images of the colorimetric THI gel were correlated with TVC of food at 4 ℃ and 25 ℃, respectively. These results support that the proposed THI is potential for real-time, accurate, non-destructive, visually, and quantitatively monitoring food freshness during food supply chain distribution. Graphical Abstract
研究领域:
食品科学
·
材料科学
✓ 已验证
DOI
高影响因子
LWT-FOOD SCIENCE AND TECHNOLOGY
·
2022
·
IF 6.056
Lin Wang,Feng Li,Sufang Wang,Jinsong Wu,Wenhui Zhang,Yan Zhang,Wentao Liu
The application of enzyme-inorganic hybrid nanoflowers in time-temperature indicators (TTIs) was studied for the first time. Lipase@Cu 3 (PO 4 ) 2 hybrid nanoflowers were prepared by the interaction between lipase and copper ions. Compared with free lipase, the activity of lipase in the nanoflowers was increased by 137%, and the storage stability was also improved significantly. Based on the enzymatic reaction between lipase and glycerol triacetate, six TTI prototypes with different concentrations of lipase@Cu 3 (PO 4 ) 2 hybrid nanoflowers were investigated. The color of the six TTIs changed from purple to yellow, and finally to green, and the activation energies were 46.86 kJ/mol, 51.17 kJ/mol, 54.99 kJ/mol, 60.00 kJ/mol, 62.17 kJ/mol, and 65.63 kJ/mol, respectively. The shelf life of TTIs can be determined by changing the ratio of lipase@Cu 3 (PO 4 ) 2 hybrid nanoflowers to glycerol triacetate, therefore the TTIs can be easily applied to real-time safety evaluation of many perishable foods.
研究领域:
食品科学
·
生物化学
✓ 已验证
产品关联
DOI
高影响因子
ACS Nano
·
2023
·
IF 17.1
Chao Huang,Yuanyuan Shang,Jiachuan Hua,Yadong Yin,Xuemin Du
Vaccines are undoubtedly a powerful weapon in our fight against global pandemics, as demonstrated in the recent COVID-19 case, yet they often face significant challenges in reliable cold chain transport. Despite extensive efforts to monitor their time–temperature history, current time–temperature indicators (TTIs) suffer from limited reliability and stability, such as difficulty in avoiding human intervention, inapplicable to subzero temperatures, narrow tracking temperature ranges, or susceptibility to photobleaching. Herein, we develop a class of structural color materials that harnesses dual merits of fluidic nature and structural color, enabling thermal-triggered visible color destruction based on triggering agent-diffusion-induced irreversible disassembly of liquid colloidal photonic crystals for indicating the time–temperature history of the cold chain transport. These self-destructive structural color liquids (SCLs) exhibit inherent irreversibility, superior sensitivity, tunable self-destructive time (minutes to days), and a wide tracking temperature range (−70 to +37 °C). Such self-destructive SCLs can be conveniently packaged into flexible TTIs for monitoring the storage and exposure status of diverse vaccines via naked-eye inspection or mobile phone scanning. By overcoming the shortcomings inherent in conventional TTIs and responsive photonic crystals, these self-destructive SCLs can increase their compatibility with cold chain transport and hold promise for the development and application of the next-generation intelligent TTIs and photonic crystals.
研究领域:
材料科学
·
生物医学工程
·
光学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF FOOD ENGINEERING
·
2021
·
IF 5.354
Tingting Gao,Da-Wen Sun,You Tian,Zhiwei Zhu
A time-temperature indicator (TTI) based on gold-silver core-shell nanorods (Au@Ag NRs) was developed to monitor the quality degradation of pasteurized milk in the cold chain. Changes of longitudinal plasmon peak wavelength, micro-morphology and colour of the Au@Ag NRs TTI at 4 °C, 15 °C, 25 °C, and 35 °C were investigated, and kinetic characteristics and temperature dependence of the TTI were studied. Pasteurized milk was also stored at the same temperatures, and changes of titratable acidity (TA), pH values and total bacterial count (TBC) were determined and fitted to characterize the kinetic properties of each quality attributes at different storage temperatures. Besides, the Arrhenius equation was used to calculate the activation energy ( E a ) values, among which the Au@Ag NRs TTI, TA, pH and TBC showed E a values of 70.36, 65.67, 127.87 and 52.33 kJ/mol, respectively. Results showed that the TTI and TA possessed more similar E a values, suggesting that the TTI could predict the TA of pasteurized milk in the cold chain more accurately. Furthermore, a dynamic temperature test was performed to verify the applicability and reliability of the TTI. Temperature accumulation effects were calculated and effective temperatures ( T eff ) of the TTI and the pasteurized milk were determined as 287.4 K and 287.3 K, respectively, which indicated high sensitivity and good applicability of the TTI for quality monitoring of the real milk system, showing great application potentials for cold chain intelligent labels.
研究领域:
食品科学
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
Advanced Optical Materials
·
2023
·Vol. 11
·期 8
·2202654
·
IF 9
Yifan Song,Jiaren Du,Rujun Yang,Cunjian Lin,Wenjing Chen,Zishuang Wu,Hengwei Lin,Xi Chen,Yixi Zhuang,Rong-Jun Xie
Time–temperature indicator (TTI) technologies allow for nondestructive and real-time quality management of perishable products during the entire transport–storage process, which provides an important guarantee for the product safety of end users. However, the existing TTI technologies still have shortcomings in recyclability, sensitivity, and environmental tolerance, limiting their widespread applications. Herein, a new TTI route based on the light storage effect in persistent luminescent (PersL) materials is proposed. Such TTI is designed on account of the principle that the release rate of light-induced trapped carriers in PersL materials is closely dependent on the storage time and temperature, enabling to establish a correlation between the number of residual carriers and the freshness of perishable products. Taking KZnF 3 :Mn 2+ as a model material, the light-storage-based TTI technology shows excellent recyclability, reliability, and environmental stability. This work reveals great potentials of PersL phosphors as information recording materials in advanced TTI application and next-generation biological detection technology.
研究领域:
材料科学
·
食品安全
·
生物检测技术
✓ 已验证
产品关联
DOI
高影响因子
Advanced Materials Technologies
·
2023
·Vol. 8
·期 17
·2300360
·
IF 6.8
Yanhui Zhan,Xiaoyu Qin,Kuan Wang,Yong Zhang,Juan Song,Yan Qian,Quli Fan
High-contrast and stably visualized ambient or luminescent color-switching can be achieved by thermal-induced non-invasive chemical reaction for naked-eye threshold temperature indication. The clear and visible output signal of these indicators arises from the large absorption/emission spectral changes upon heating. However, such chemical reactions are difficult to realize in solid-state, especially in the high-temperature region. Herein, a series of naked-eye high-temperature threshold film indicators have been developed based on the solid-state in situ thermal decomposition reaction of difluoroboron β -diketonate derivative. These thermosensitive films feature three high-contrast visible outputs of ambient thermochromism, fluorescence color change, and luminescence ON/OFF switching, which can be easily detected with the naked eye. The PR-PS film of (E)-4-(2-(6-bromopyren-1-yl)vinyl)-2,2-difluoro-6-phenyl-2H-1 λ 3 ,3,2 λ 4 -dioxaborinine (PR) doped in polystyrene (PS) polymer matrix achieved high sensitivities related to change of ratiometric luminescence and fluorescence intensity up to 230%°C −1 and 1.85%°C −1 , respectively. Furthermore, the polymer matrix with different glass transition temperatures enables programmable tuning of threshold temperature from 120 to 180 °C. These thermosensitive films show clear and high-contrast color changes and emission turn-off in real-time with consistent air stability, high photostability, and waterproofing property. This shows considerable potential in outdoor robust high-temperature threshold sensing and information storage.
研究领域:
材料科学
·
化学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）