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CARBOHYDRATE POLYMERS · 2019 · IF 6.044

Ultra-fast and probe-free cellulose biosensor for visual detection of Cu2+ ions in biological samples

R.J. Wang,L.W. Zhang,R. Liu,L. Liu,J.M. Yao

Novel, portable, probe-free, liquid cellulose biosensor was explored via a facile one-pot process for Cu 2+ ions detection by naked eyes. The as-prepared biosensor displayed specific recognition towards Cu 2+ ions in aqueous solution, even in complex urine and serum samples within 10 s, showing fast response characteristic. There is barely any interference on the Cu 2+ ions detection by other metal ions or other complex substances in urine and serum, and the corresponding detection limit is as low as 1.185, 1.9309 and 1.9154 ppm, respectively. Moreover, the cellulose biosensor could act as an excellent candidate to sense Cu 2+ ions in biological samples including urine and serum from SD rats with satisfying accuracies and biocompatibility. This study exploits a potential application of cellulose in biosensing and monitoring related to Cu 2+ ions.

研究领域: 分析化学 · 生物传感 · 环境监测 · 临床诊断 · 材料科学 · 毒理学
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