Science Advances
·
2025
·Vol. 11
·期 19
·
IF 12.5
Hengjia Zhu,Qiyu Deng,Junzhi Li,Ling Yang,Hegeng Li,Zhipeng Zhao,Zuochen Wang,Chunlin Pang,Yiyuan Zhang,Vincent Chi-Hang Lui,Wei Li,Xiaobo Yin,Liqiu Wang
Precision processing of various liquids while maintaining their purity holds immense potential for many applications. However, liquids tend to leave residues that contaminate handling tools and compromise volumetric precision, necessitating contactless strategies to prevent liquid loss. Biological and chemical samples carried by fluids can be sensitive to physical stimuli, demanding mild but effective means to preserve integrity. Here, we report a sound-controlled fluidic processor for complete and well-controlled microfluidic functions, including moving, merging, mixing, and cleaving, in contactless and harmless manners. The processor generates an acoustophoretic force field that serves as a versatile toolbox for manipulating droplets with surface tension from 17.9 to 72 millinewtons per meter and volume from 1 nanoliter to 3 milliliters, offering a wealth of operations crucial to fundamental biomedical and chemical practices.
研究领域:
生物医学工程
·
化学工程
·
声学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nanomaterials
·
2022
·Vol. 12
·期 6
·899
·
IF 5.719
Xiaoyan Wu,Wei Li,Qingrong Chen,Caixia Xu,Jiamian Wang,Lingyuan Wu,Guodong Liu,Weiping Wang,Ting Li,Ping Chen,Long Xu
Light-induced degradation (LID) phenomenon is commonly found in optoelectronics devices. Self-healing effect in halide lead perovskite solar cells was investigated since the electrons and holes in the shallow traps could escape easily at room temperature. However, the degradation in the semiconductors could not easily recover at room temperature, and many of them needed annealing at temperatures in the several hundreds, which was not friendly to the integrated optoelectronic semiconductor devices. To solve this problem, in this work, LID effect of photocurrent in p-type Mg-doped gallium nitride thin films was investigated, and deep defect and vacancy traps played a vital role in the LID and healing process. This work provides a contactless way to heal the photocurrent behavior to its initial level, which is desirable in integrated devices.Keywords:Mg-doped gallium nitride;light-induced degradation;photocurrent device;contactless healing
研究领域:
材料科学
·
光电子学
·
半导体物理
✓ 已验证
DOI
PubMed
高影响因子
ANALYTICAL BIOCHEMISTRY
·
2012
·Vol. 434
·期 1
·73-77
·
IF 2.996
Zhirui Song,Yue Xu,Zuanguang Chen,Jianping Yang,Xinchun Li,Zhiguang Zhang
This article describes the determination of lactate in synovia by microchip capillary electrophoresis (MCE) integrated with contactless conductivity detection (CCD). The optimal running buffer consists of 10 mM tris(hydroxymethyl)aminomethane, 1 mM HCl , and 0.1 mM hexadecyltrimethylammonium bromide (pH 9.1). The quantitative measurement of lactate in dilute synovia samples can be finished in less than 40 s. The results indicated that the peak area had a good linear relationship with lactate concentration in the range of 20 to 1000 μM, and the correlation coefficient was 0.9984. The average recovery was from 96.6% to 106.1%, and the interday relative standard deviation was less than 4.0% ( n = 6). The limit of detection (signal/noise = 3) reached 6.5 μM. To validate the assay results, we compared the current method with the high-performance liquid chromatography method by measuring lactate in synovia samples. The data analysis verified that there was no significant difference between the two methods. Due to significant features such as low cost, integration, and miniaturization, the MCE–CCD method may have great potential in clinical diagnosis.
研究领域:
分析化学
·
临床检验
·
分子诊断
·
转化医学
✓ 已验证
DOI
高影响因子
ADVANCED MATERIALS
·
2024
·Vol. 36
·期 25
·2401931
·
IF 27.4
Jiaqi He,Ruilai Wei,Xiaole Ma,Wenqiang Wu,Xiaojun Pan,Junlu Sun,Jiaqi Tang,Zhangsheng Xu,Chunfeng Wang,Caofeng Pan
Creating a large-scale contactless user-interactive sensing display (CUISD) with optimal features is challenging but crucial for efficient human–human or human–machine interactions. This study reports a CUISD based on dynamic alternating current electroluminescence (ACEL) that responds to humidity. Subsecond humidity-induced luminescence is achieved by integrating a highly responsive hydrogel into the ACEL layer. The patterned silver nanofiber electrode and luminescence layer, produced through electrospinning and microfabrication, result in a stretchable, large-scale, high-resolution, multicolor, and dynamic CUISD. The CUISD is implemented for the real-time control of a remote-controlled car, wherein the luminescence signals induced by touchless finger movements are distinguished and encoded to deliver specific commands. Moreover, the distinctive recognition of breathing facilitates the CUISD to serve as a visual signal transmitter for information interaction, which is particularly beneficial for individuals with disabilities. The paradigm shift depicts in this work is expected to reshape the way authors interact with each other and devices, discovering niche applications in virtual/augmented reality and the metaverse.
研究领域:
材料科学
·
生物医学工程
·
电子信息工程
✓ 已验证
DOI
高影响因子
ADVANCED MATERIALS
·
2021
·Vol. 33
·期 42
·2102886
·
IF 30.849
Zhen Tang,Shiquan Lin,Zhong Lin Wang
Contact electrification (CE) is a common physical phenomenon, and its mechanisms for solid–solid and liquid–solid cases have been widely discussed. However, the studies about liquid–liquid CE are hindered by the lack of proper techniques. Here, a contactless method is proposed for quantifying the charges on a liquid droplet based on the combination of electric field and acoustic field. The liquid droplet is suspended in an acoustic field, and an electric field force is created on the droplet to balance the acoustic trap force. The amount of charges on the droplet is thus calculated based on the equilibrium of forces. Further, the liquid–solid and liquid–liquid CE are both studied by using the method, and the latter is focused. The behavior of negatively precharged liquid droplet in the liquid–liquid CE is found to be different from that of the positively precharged one. The results show that the silicone oil droplet prefers to receive negative charges from a negatively charged aqueous droplet rather than positive charges from a positively charged aqueous droplet, which provides a strong evidence about the dominant role played by electron transfer in the liquid–liquid CE.
研究领域:
静电学
·
界面物理
·
软物质物理
·
微流控
✓ 已验证
DOI
高影响因子
RSC Advances
·
2018
·Vol. 8
·期 33
·18266-18271
·
IF 2.936
Jing Zhang,Xuan Wei,Yuanhang Wang,Bo Ren,Litao Zhao,Zhaoyan Wang,Qiaosheng Pu
Change in cation concentration, including that of potassium and sodium, is characteristic of apoptosis, therefore it is significant to detect cation concentration changes. In this work a rapid, sensitive, and practical method was developed for the determination of Na+ and K+ concentration in HeLa cells during emodin induced apoptosis by a low-cost capillary electrophoresis device with capacitively coupled contactless conductivity detection (CE-C4D). Under the optimized conditions, both ions were baseline separated in 4 min with 40 mM MES/40 mM His containing 1 mM 18-crown-6 as the separation buffer at pH 6.0. The limit of detections (LODs) and limit of quantifications (LOQs) were 0.47–1.15 μM and 1.58–3.86 μM, respectively. The precision for migration times and peak areas was below 0.56% and 3.74%, respectively. The data proved that the concentration of cations in cells can be accurately quantified. It was found that the K+ concentration decreased from 82.2 μM to 52.7 μM, and the Na+ concentration increased from 62.4 μM to 127.2 μM during the process of apoptosis when the cell density was 1 × 105 cells per mL. The low-cost CE-C4D provides a convenient way to decipher the interaction of Na+ and K+ in the regulation of cell apoptosis.
研究领域:
分析化学
·
生物化学
·
细胞生物学
·
药理学
✓ 已验证
DOI
PubMed
高影响因子
Frontiers in Chemistry
·
2022
·
IF 5.545
Ge Mengyi,Zhao Wenfeng,Han Yue,Gai Hongwei,Zong Chenghua
This report presents a contactless and robust dielectric microspheres (DMs)-assisted surface enhanced Raman scattering (SERS) enhancement method to improve SERS detection sensitivity detection sensitivity. DMs that could focus and collect light were embedded within the polydimethylsiloxane (PDMS) film to avoid direct contact with the analytical solution and improve detection reliability. The as prepared DMs embedded PDMS (DMs-PDMS) film was integrated with a microfluidic technique to enhance the SERS signal of a liquid substrate. Detection in microfluidic systems can reduce reagent consumption, shorten assay time, and avoid evaporation of the colloid substrate solution. The robustness and potential influencing factors of DMs-PDMS film assisted SERS enhancement (DERS) were evaluated using 4-aminothiophenol (4-ATP) as the Raman probe. The sensing performance of the proposed method toward dipicolinic acid (DPA) was evaluated, and an evident signal intensification was obtained. Remarkably, the DMs-PDMS film can also be implemented on solid substrates. A proof-of-concept experiment was performed by covering the DMs-PDMS film directly over an AgNPs@Si solid substrate wherein a 5.7-fold sensitivity improvement was achieved.
研究领域:
分析化学
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nano Energy
·
2023
·
IF 17.6
Guomin Ye,Taosha Jin,Xueke Wang,Yi Chen,Qiang Wu,Yanfen Wan,Peng Yang
Multimodal integrated flexible electronic skin offers exceptional processing capability and versatility in various application scenarios. Researchers are devoting to developing nanomaterials or nano-devices with multidisciplinary functions. Herein, a trinary-mode integrated flexible electronic skin (E-Skin) was designed for physiological perception and contactless kinematics pattern recognition, which serves as real-time health monitor, electrode patch and contactless sensor. The composite film of liquid metal particles and thermoplastic polyurethane elastomers (LMPs@TPU) was prepared by a combination of electrostatic spinning, electrostatic spraying, and knife coating , which can be stretched up to 404.7 % at stress of 1Mpa. The film was endowed three functional modes through different forms of encapsulation, which allows for (1) detecting human arthrosis movements, muscle stretching, and inspiration, (2) achieving a real-time capture of Electrocardiogram (ECG) and surface electromyography (sEMG), and a Human-Machine Interaction (HMI) system for game control based on sEMG signals was also developed, (3) a contactless sensor combining with a machine learning model which realizes the recognition of human motion patterns with a receiver operating characteristic curve and area under curve score (ROC-AUC-score) of 0.99. The three models of this E-Skin highlight the significant potential for industrialization in various fields, such as HMI, physiological perception, virtual reality, and motion analysis.
研究领域:
生物医学工程
·
材料科学
·
人工智能应用
✓ 已验证
产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2024
·
IF 8.1
Ru Song,Ningshuang Zhang,Peng Wang,Hao Ding,Shiyou Li
Solar interfacial evaporation is a low-cost strategy for desalination and water purification. However, for most evaporators, the coplanar configuration of light absorption and water evaporation results in a confined evaporation surface and salt deposition problems. Here, a contactless 3D Janus evaporator (Ag-NSP@BFP) with a core/shell structure is designed by wrapping Ag nanoparticles (Ag-NPs) decorated nickel sponge (Ag-NSP) using bamboo fiber paper (BFP). The superhydrophobic Ag-NSP core (absorber) achieves highly efficient light absorption and photothermal conversion. Meanwhile, the superhydrophilic BFP shell not only provides a larger evaporation area (side surfaces as evaporation surfaces) but also forms a 2D water channel to ensure sufficient water supply. Furthermore, polystyrene foam (EPS) isolates photothermal material from bulk water, minimizing heat transmission losses dramatically. The 3D Janus evaporator increases the evaporation area and harvests energy from the ambient environment, achieving an evaporation rate of up to 2.77 kg m −2 h −1 and an energy conversion efficiency of 105.2%. Moreover, the Janus structure effectively inhibits salt accumulation on the photothermal surface and exhibits a good purification effect on wastewater containing dyes and heavy metal ions. Thus, combining a 3D evaporator with Janus structure to achieve efficient salt-resistant evaporation provides a new design idea for stable seawater desalination and wastewater purification.
研究领域:
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2014
·
IF 3.583
Haiyun Zhai,Jiangmei Li,Zuanguang Chen,Zihao Su,Zhenping Liu,Xiao Yu
A simple glass/PDMS microfluidic chip for on-line sample pretreatment and contactless conductivity detection, which consisted of a 0.17 mm-thick glass cover and a PDMS substrate embedded with an SPE monolithic column, was presented in this paper. Using this integrated microchip system, sample extraction, injection, separation and detection were automatically performed in sequence. A sample of auramine O was concentrated by molecularly imprinted SPE (MISPE), eluted to sample reservoir, and injected by electromigration into separation channel for electrophoresis separation and contactless conductivity detection, with the calculated detection limit (S/N = 3) being 2.5 μg mL − 1 . The monolithic column was utilized to quantitatively extract auramine O , yielding an on-line enrichment factor of about 12. The microchip system is reliable and applicable to the analysis of auramine O in food sample.
研究领域:
分析化学
·
微流控技术
·
食品安全
·
分子印迹技术
·
电泳学
·
生物医学工程
✓ 已验证
DOI
高影响因子
MICROSYSTEM TECHNOLOGIES-MICRO-AND NANOSYSTEMS-INFORMATION STORAGE AND PROCESSING SYSTEMS
·
2015
·Vol. 22
·期 4
·677-686
·
IF 0.875
Wang Lei,Liu Wenfang,Li Shuang,Liu Tingting,Yan Xingxing,Shi Yuye,Cheng Zeneng,Chen Chuanpin
Conventional ways to produce microfluidic devices cost a lot due to the requirements for cleanroom environments and expensive equipment, which prevents the wider applications of microfluidics in academia and in industry. In this paper, a dry film photoresist was utilized in a simple way to reduce the fabrication cost of microfluidic masters. Thus, a fast prototyping and fabrication of microstructures in polydimethylsiloxane microchips through a replica molding technology was achieved in a low-cost setting within 2.5 h. Subsequently, major manufacturing conditions were optimized to acquire well-resolved microfluidic molds, and the replicated microchips were validated to be of good performance. A T-junction channel microchip was fabricated by using a dry film master to generate water droplets of uniform target size. Meanwhile, a gated injection of fluorescein sodium and a contactless conductivity detection of Na + were both performed in a crosslink channel microchip via capillary electrophoresis, in other words, this fast prototyping and fabrication method would be an efficient, economical way to embody structural design into microfluidic chips for various applications.
研究领域:
微流控技术
·
材料科学
·
生物技术
·
分析化学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）