RSC Advances
·
2019
·Vol. 9
·期 11
·6254-6266
·
IF 3.049
Ming-Ming Tu,Jing-Jie Xu,Yun-Ren Qiu
In this study, acrylic acid (AA) and sulfonated hydroxypropyl chitosan (SHPCS) were covalently grafted on the PSf membrane surface to improve its hemocompatibility. First, the modified AA-PSf membrane was obtained through the Friedel–Craft reaction between acrylic acid and the PSf membrane surface. Then, the modified SHPCS-AA-PSf membrane was prepared by grafting SHPCS onto the AA-PSf membrane surface via the dehydration acylation of the carboxyl group of the AA-PSf membrane with the amino group of SHPCS. ATR-FTIR and XPS measurements confirmed that the –COOH group and SHPCS were successfully grafted onto the surface of the PSf membrane. The modified PSf membranes showed suppressed platelet adhesion and lower protein adsorption (161 μg cm−2) compared with the pristine PSf membrane (341 μg cm−2). Hemocompatibility testing showed that modified membrane materials had a prolonged clotting time, plasma recalcification time (PRT), activated partial thromboplastin time (APTT), thrombin time (TT), and prothrombin time (PT). All of these results indicated that the surface modification of the PSf membrane with acrylic acid and SHPCS had good hemocompatibility and anticoagulant property.
研究领域:
材料科学
·
生物材料
·
生物医学工程
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产品关联
DOI
PubMed
高影响因子
IEEE ELECTRON DEVICE LETTERS
·
2013
·Vol. 34
·期 11
·1424-1426
·
IF 2.789
Yupeng Zhang,Ying Zhang,Bo Fu,Wei Li,Wenbin Guo,Shengping Ruan,Dali Liu,Yu Chen
Sodium titanate Na
2
Ti
6
O
13
nanorods were synthesized by a hydrothermal method and characterized by X-ray diffraction and scanning electron microscopy. Then, the material was coated on a Al
2
O
3
ceramic substrate to fabricate humidity sensors using Ag-Pd as interdigitated electrodes. The sensor shows high humidity sensitivity and fast response and recovery. The impedance changes by five orders of magnitude over a relative humidity (RH) range from 11% to 95%. At the frequency of 100 Hz, response and recovery times are both <;2 s, and the maximum hysteresis is <;3% RH. In addition, the complex impedance at different RH was investigated to understand the sensing mechanism. The results indicate potential applications of sodium titanate for fabricating high-performance humidity sensors.
研究领域:
材料科学
·
传感器技术
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DOI
高影响因子
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
·
2014
·Vol. 14
·期 6
·4303-4307
·
IF 1.339
Zhang Yupeng,Wu Jian,Zhang Ying,Guo Wenbin,Ruan Shenping
Na2Ti3O7 nanotubes was synthesized by a hydrothermal method, and characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). Then the material was coated on Al2O3 ceramic
substrate to fabricate humidity sensors using Ag–Pd as interdigitated electrodes. The sensor shows high humidity sensitivity and quick response-recovery time. The impedance changes about five orders of magnitude within humidity range from 11% to 95% relative humidity (RH). At the frequency
of 100 Hz, the response time is 2 s and recovery time is 4 s, and the maximum hysteresis is less than 3% RH. Moreover, complex impedance property at different RH was investigated to study sensing mechanism. The results indicate the potential applications of Na2Ti3O7
nanotubes for fabricating high-performance humidity sensors.
研究领域:
材料科学
·
传感器技术
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DOI
PubMed
高影响因子
Nanoscale
·
2016
·Vol. 8
·期 16
·8696-8703
·
IF 7.76
Fangxu Ji,Xianpei Ren,Xiaoyao Zheng,Yucheng Liu,Liuqing Pang,Jiaxing Jiang,Shengzhong (Frank) Liu
By taking advantages of both grinding and sonication, an effective exfoliation process is developed to prepare two-dimensional (2D) molybdenum oxide (MoO3) nanosheets. The approach avoids high-boiling-point solvents that would leave a residue and cause aggregation. Gas sensors fabricated using the 2D-MoO3 nanosheets provide a significantly enhanced chemical sensor performance. Compared with the sensors using bulk MoO3, the response of the 2D-MoO3 sensor increases from 7 to 33; the sensor response time is reduced from 27 to 21 seconds, and the recovery time is shortened from 26 to 10 seconds. We attribute the superior performance to the 2D-structure with a much increased surface area and reactive sites.
研究领域:
材料科学
·
化学传感器
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产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2025
·
IF 8.2
Yang Qu,Ran Wei,Shengjun Cheng,Xianda Liu,Weifeng Zhao,Changsheng Zhao
In the process of blood purification, the use of anticoagulants is necessary to prevent treatment interruptions due to blood clotting. Currently, traditional liquid anticoagulant medications, which enter the bloodstream, may lead to safety concerns, such as internal bleeding and thrombocytopenia. To address these issues, we prepared solid anticoagulant microspheres based on polyurethane (PU) through one-pot in situ solution polymerization and phase conversion methods. The microspheres prolong the activated partial thromboplastin time (APTT) and thrombin time (TT) by 30–40 s and demonstrate good blood compatibility. Interestingly, we find that polyurethane in the microspheres has the ability to selectively bind thrombin, like the anticoagulant mechanism of hirudin. The strong binding between PU and thrombin is confirmed through microscale thermography (MST) (the dissociation constant Kd is about 71 μM). Furthermore, the anticoagulant microspheres, in combination with other studies of anticoagulation mechanisms, are found to inhibit multiple steps in the coagulation cascade. More importantly, the noninvasive microspheres do not release PU into the bloodstream, ensuring the safety of anticoagulation therapy and suggesting significant potential for application in the field of blood purification.
研究领域:
生物医学工程
·
材料科学
·
血液学
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产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Chen Chen,Haoyu Yuan,Xiaoming Wang,Na Wang,Yan Lin,Yan He,Fei Wang
Among several promising applications of gas hydrate-based technologies, storage and transportation of gases (H 2 , CH 4 , CO 2, etc.) in the form of hydrate has aroused extensive concern. Currently, developing an effective and recyclable promoter holds the key to achieving the industrial application of hydrates. Herein, we proposed sulfonated magnetic polymer nanoparticles as the promoter for methane hydrate formation, which are synthesized by sulfonating the magnetic Fe 3 O 4 particle in the soap-free emulsion system. Then the performance of the promoter was evaluated with regard to induction time, reaction time, and storage capacity at different concentrations. Hydrate formation results showed that when the mass concentration was 20 g/L, the storage capacity can reach up to 137.0 ± 2.8 v/v with the reaction time of 28 min while the induction time was only with the range of 44.1 ± 13.52 min. Further, the hydrate structure (sI) and dynamic occupancy change of 5 12 6 2 and 5 12 cage were studied by the in-situ Raman at micro level and meanwhile the macroscopic morphology observation was also conducted. In addition to the high performance described above, the promoter also exhibited high-performance reliability in 15 cycles of hydrate formation experiments. This indicates that the promoter has great promise on economic benefit, environmental friendliness and recyclability for application in the methane hydrate-based technology.
研究领域:
化学工程
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
IONICS
·
2024
·Vol. 30
·期 3
·1785-1793
·
IF 2.4
Yü Jingzhao,Zhang Yuqing,Wang Liying,Yang Xijia,Yang Yue,Jiang Ke,Lü Wei,Sun Xiaojuan
AlGaN is an ideal material for fabricating ultraviolet (UV) photodetectors targeting the solar-blind wavelength range. However, the performance of UV detectors based on AlGaN is still limited by its material quality and effective p-type doping. Herein, we propose an external modulation method by combining AlGaN with two-dimensional MXene (Ti 3 C 2 T x ) to construct Ti 3 C 2 T x /AlGaN heterostructures. It has been shown that Ti 3 C 2 T x undergoes a transition from a metallic material to a semiconductor depending on oxidation, and the performance of Ti 3 C 2 T x /AlGaN detectors could be adjusted accordingly. The effect of oxidation process of Ti 3 C 2 Tx on performance of Ti 3 C 2 T x /AlGaN photodetectors has been investigated systematically. The optimized devices exhibited a rise time of 72 ms and a decay time 30 ms, achieving a responsivity of 3000 mA/W under 270 nm UV light irradiation.
研究领域:
光电子学
·
半导体器件
·
材料科学
·
纳米技术
✓ 已验证
DOI
高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Ruiling Li,Ningzhe Wang,Chao Ma,Jiacheng Wang,Jing Wang,Xin Yang
To improve the 3D printing quality of emulsion gels, this study prepared ovalbumin-gellan gum emulsion gel (OG-EG) by adding gellan gum to peanut oil-ovalbumin emulsion. The effects and mechanisms of ultrasound time and storage time on the physicochemical properties, 3D printing accuracy, microstructure, and protein structure of OG-EG were investigated. Ultrasound and storage treatment enhanced the viscoelasticity, hardness, and compactness of the network structure of OG-EG. At ultrasound time of 3.5 min and storage time of 4 min, the printed products of OG-EG exhibited uniform filaments and stable structures, and could accurately print fine patterns with a size of 3 mm with a printing accuracy of 91 %. Ultrasound and storage treatments resulted in the formation of a stable and robust network structure in OG-EG, with emulsified oil droplets filling the gel network. The synergistic interaction of these components led to the development of an emulsion gel with excellent printing performance.
研究领域:
食品科学
·
生物化学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF ELECTRONIC MATERIALS
·
2021
·Vol. 51
·期 1
·214-222
·
IF 1.938
Tian Chunxia,Tian Xi-ang,Li Yu,Wang Zhijun,Liu Li
Porous SnO 2 with high sensitivity and fast response has attracted much attention. Herein, we prepared 3D porous SnO 2 using carbon balls as a template and studied the effects of sintering time (1 h, 2 h, 3 h, 4 h) at a certain calcination temperature of 500℃ and Ho doping on the gas-sensing performance of 3D porous SnO 2 . The gas-sensing test results show that, compared with the samples obtained under other sintering time, the gas-sensing property of 3D porous SnO 2 calcined for 2 h has the highest gas sensitivity of 31 in the 50-ppm formaldehyde environment. Among the samples doped with Ho, 3D porous SnO 2 with a doping amount of 3.5% has the highest sensitivity of 65 at operating temperature of 230℃, which is twice as long as pure 3D porous SnO 2 with a calcination time of 2 h. Moreover, the sample has good selectivity, low detection limit, and good linearity. These excellent gas-sensing characteristics are mainly due to the unique morphology of 3D porous SnO 2 , more oxygen vacancies, and the influence of Ho doping. Therefore, the gas-sensing performance of the metal oxide semiconductor material can be further improved by forming the porous nanocomposite material. Graphical Abstract
(a) Response recovery time of SnO 2 obtained under different calcination times; (b) Response recovery time of SnO 2 doped with different Ho content.
研究领域:
材料科学
·
纳米技术
·
化学传感器
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产品关联
DOI
高影响因子
Desalination and Water Treatment
·
2024
·
IF 1
Yanzhuo Zhang,Haiqin Zhang,Jing Zhao,Xiaozhuan Zhang,Zhiguo Cao,Binbin Jiang
ABSTRACT This study investigated the removal efficiency of fluoride ions (F – ) using polyethyleneimine modified diatomite earth (PEI&DT) in a fixed bed column under different conditions. Scanning electron microscopy showed that the PEI&DT had high porosity and thermogravimetric analysis showed that the diatomite was successfully modified by polyethyleneimine (PEI). Adsorption of F – by PEI&DT was measured in the fixed bed column using breakthrough time and saturation time, which increased with increasing bed height, but decreased with increasing F – concentration and flow rate. The Thomas model, which had a very good fit (average = R 2 > 0.9632), showed that the maximum q 0 value was 97.06 mg/g. The Yoon–Nelson model predicted theoretical required times (τ theo ) were close to the experimental values (τ exp ), and the mean error (β) < 9% showed the model was accurate. These results demonstrated that PEI&DT has high potential as an adsorbent for the removal of F – in a fixed bed column.
研究领域:
环境科学
·
化学工程
✓ 已验证
DOI
高影响因子
Microbiome
·
2025
·Vol. 13
·期 1
·1-17
·
IF 12.7
Liu Youhua,Liu Jiaqi,Ren Ruiti,Xin Zimeng,Luo Yaojun,Chen Yushi,Huang Chaoqun,Liu Yuxi,Yang Tongyudan,Wang Xinxia
Background Although short-term high-fat diet (S-HFD) and long-term high-fat diet (L-HFD) induce metabolic disorder, the underlying epigenetic mechanism is still unclear. Results Here, we found that both 4 days of S-HFD and 10 weeks of L-HFD increased mRNA m 6 A level in epididymal white adipose tissue (eWAT) and impaired metabolic health. Interestingly, S-HFD activated transposable elements (TEs), especially endogenous retroviruses (ERVs) in eWAT, while L-HFD activated long interspersed elements (LINEs). Subsequently, we demonstrated that both S-HFD and L-HFD increased m 6 A level of Ehmt2 and decreased EHMT2 protein expression and H3K9me2 level, accounting for activation of ERVs and LINEs. Overexpression of EHMT2 in eWAT or inhibition of ERVs and LINEs by antiviral therapy improved metabolic health under HFD feeding. Notably, we found that both short-term and long-term HFD feeding increased Fimicutes/Bacteroidota ratio and decreased the gut microbiome health index. Fecal microbiota transplantation (FMT) experiments demonstrated that gut microbiota from S-HFD and L-HFD was responsible for increased m 6 A level in eWAT, resulting in glucose intolerance and insulin insensitivity. Furthermore, we identified that both S-HFD and L-HFD increased the abundance of the gut microbial metabolite homogentisic acid (HGA), and HGA level was positively correlated with unclassified_f__Lachnospiraceae which was both increased in S-HFD and L-HFD feeding mice. Administration of HGA increased the m 6 A level of Ehmt2 and decreased the EHMT2 protein expression and H3K9me2 level in eWAT, leading to metabolic disorder in mice. Conclusions Together, this study reveals a novel mechanism that S-HFD and L-HFD induce metabolism disorder through gut microbiota-HGA-m 6 A- Ehmt2 -ERV/LINE signaling. These findings may provide a novel insight for prevention and treatment of metabolism disorder upon short-term or long-term dietary fat intake.
Video
研究领域:
分子生物学
·
营养学
·
微生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Physical Chemistry C
·
2010
·
IF 4.224
Zhengjun Wang,Jie Liu,Feijiu Wang,Siya Chen,Hui Luo,Xibin Yu
Uniform and monodisperse ZnSnO3 cubic crystallites were prepared via a solution process involving the reaction of zinc sulfate and sodium stannate at a reaction temperature as low as 0 °C without any surfactant. The size was readily controlled from 40 to 600 nm by varying the reaction temperature. The possible formation mechanism of cubic crystallites was attributed to a nucleation assembly process. The as-fabricated sensors based on ZnSnO3 cubic crystallites showed high sensitivity, fast response, and short recovery times toward HCHO gas. And as the particle-size of ZnSnO3 cubic crystallites decrease, the sensitivity of gas sensors based on them increases and the recovery time shorten rapidly. The detection limit of ZnSnO3 cubic crystallites sensor can reach as little as lower than one per million for HCHO. The performance of a home-built ZnSnO3 cubic crystallites sensor was even better than the competing SnO2 and In2O3 sensor, making this material interesting for sensor devices.
研究领域:
材料科学
·
纳米技术
·
传感器
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）