NEW JOURNAL OF CHEMISTRY
·
2023
·Vol. 47
·期 10
·4667-4673
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IF 3.3
Yufei Lei,Yujie Li,Chen Liu,Liqiong He,Qian Li,Lifu Liao,Xilin Xiao
A convenient and portable smartphone-assisted method for the colorimetric detection of uranyl ions (UO22+) in aqueous solutions is proposed using rifampicin and 2-(5-bromo-2-pyridylazo)-5-diethylaminophenol (Br-PADAP) as chromogenic agents. The addition of UO22+ would cause reaction with chromogenic agents to form complexes, changing the colour from orange to dark red in the rifampicin system and from yellow to light pink in the Br-PADAP system. To achieve the on-site estimation of the trace UO22+ concentration range, digital images of colour changes captured by the smartphone under fixed lighting conditions were imported into the built-in application named “Detect” to obtain HSV (hue, saturation, and value) and HSL (hue, saturation, lightness) information, which could be associated with the concentration of uranyl ions. For more precise laboratory-level detection, ultraviolet-visible (UV-vis) spectroscopy was employed as well. The absorbance of the rifampicin system exhibited strong linearity with the UO22+ concentration in the range from 4 to 50 μM at 375 nm with a method detection limit (MDL) of 3.17 μM by the UV-vis-based method, while that of Br-PADAP system had a linear relationship with the concentration from 0.9 to 7 μM at 562 nm with an MDL of 0.89 μM. The two strategies may be combined to detect UO22+ across a larger concentration range, and this method has been successfully used to analyze real samples including soil around uranium mines.
研究领域:
分析化学
·
环境科学
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产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2023
·
IF 8.8
Junjun Wang,Yue Tang,Jia Zheng,Zhengmin Xie,Jianli Zhou,Yuangen Wu
Herein, a colorimetric biosensor for histamine detection in meat is first established based on the enhancement of DNAzyme with peroxidase-mimic activity. Histamine can boost the generation of G-quadruplex sequences, and make them more easily bond with hemin to produce many DNAzyme molecules. In addition, histamine increases the affinity of DNAzyme to the substrate 3,3′,5,5′-tetramethylbenzidine (TMB). Therefore, the obtained DNAzyme can catalyze H 2 O 2 and dissolved oxygen to produce many reactive oxygen species (ROS), which cause the TMB molecule to lose two electrons and generate yellow products, exhibiting a clear absorption peak at 450 nm. The colorimetric biosensor has excellent sensitivity, and the detection limit is as low as 38 μg·L −1 for histamine. Moreover, the biosensor has high selectivity and anti-interference ability, and exhibits a good recovery rate in actual meats. The above results show that the strategy has potential for application in the detection of trace histamine in meats.
研究领域:
生物化学
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食品科学
·
分析化学
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产品关联
DOI
PubMed
高影响因子
DYES AND PIGMENTS
·
2022
·
IF 5.122
Lingfei Liu,Minjie Qian,Zhen-quan Yang,Lixia Xiao,Xiaojuan Gong,Qin Hu
In this work, a facial ratiometric fluorescence nanorpobe (RFP) based on gadolinium and nitrogen co-doped CDs ( Gd , N -CDs) was for the first time proposed for visual detection of folic acid (FA). The Gd , N -CDs were prepared by hydrothermal heating of Gd(NO 3 ) 3 ⋅6H 2 O, o-phenylenediamine (OPD), 4-aminobenzoic acid (PABA). The as-prepared Gd , N -CDs had an average particle size of 10.27 ± 0.35 nm and exhibited two emission bands at 396 and 548 nm, respectively upon excitation at 340 nm. In the presence of FA, the 560 nm emission of Gd , N -CDs was reduced while the fluorescence signal at 457 nm was enhanced, and the quantitatively determination of FA was based on the fluorescence intensity ratio (F 457 /F 560 ). The as-constructed RFP achieved a linear range of 0.0–30.0 μM and a low detection limit (LOD) of 3.43 nM. In particular, a distinguishable change in fluorescence colour from bright orange to blue enabled the development of a smartphone-assisted visual sensing platform and a paper-based analytical device for FA detection with LODs of 3.06 μM and 0.83 μM, respectively. The proposed sensing platform was successfully utilised for onsite detection of FA in vegetable, fruit and yolk samples with satisfactory results were achieved. This work highlights the application potential of smartphone-integrated CDs-based RFP as a promising portable method for on-site analysis of FA.
研究领域:
分析化学
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生物医学
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DOI
高影响因子
ANALYTICA CHIMICA ACTA
·
2024
·
IF 5.7
Meiling Chen,Yang Yang,Qinhua Chen,Lina Tang,Junlin Liu,Yujie Sun,Qiming Liu,Yulin Zhang,Guo-jun Zhang,Shaowei Chen
Cholesterol is an important lipid compound found in a variety of foods, and its level in human blood is closely related to human health. Therefore, development of rapid and accurate POCT (point-of-care testing) methods for cholesterol detection is crucial for assessing food quality and early diagnosis of diseases, in particular, in a resource-limited environment. In this study, a smartphone-assisted colorimetric biosensor is constructed based on platinum,phosphorus-codoped carbon nitride (PtCNP 2 ) for the rapid detection of cholesterol. Phosphorus-doped carbon nitride is prepared by thermal annealing of urea and NH 4 PF 6 , into which platinum is atomically dispersed by thermal refluxing. The obtained PtCNP 2 exhibits an excellent peroxidase-like activity under physiological pH, whereby colorless o -phenylenediamine (OPD) is oxidized to colored 2,3-diaminophenazine (DAP) in the presence of hydrogen peroxide (H 2 O 2 ), which can be produced during the oxidation of cholesterol by cholesterol oxidase. A smartphone-assisted visual sensing system is then constructed based on the color recognition software, and rapid on-site detection of cholesterol is achieved by reading the RGB values. Meanwhile, the generated DAP shows an apparent fluorescence signal and can realize highly sensitive detection of cholesterol by the change of the fluorescence signal intensity. Such a cholesterol sensor exhibits a wide linear detection range of 0.5–600 μg mL −1 and a low detection limit of 59 ng mL −1 . The practicality of the sensor is successfully demonstrated in the rapid detection of cholesterol in serum and food.
研究领域:
生物化学
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医学诊断
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材料科学
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产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
·
2025
·
IF 5.6
Shen Zhang,Zhuo Wang,Guiyu Meng,Chaoying Yang
In order to realize efficient detection of Congo red, fluorescence analytical method were adopted and investigated systematically. Based on the superior properties of papain and excellent performance of copper nanoclusters, papain stabilized copper nanoclusters (Cu NCs@PP) with blue fluorescence were rapidly synthesized via a one-pot method. The spherical Cu NCs@PP uniformly dispersed with an average size of about 2.5 nm and excellent stability. The as-established Cu NCs@PP emitted stronger fluorescence around 436 nm under the excitation wavelength of 358 nm. Under the optimal measurement conditions, the sensitive detection of Congo red was accomplished with linear range of 0.5–160 μM and detection limit of 0.085 μM. In the light of inner filter effect, Cu NCs@PP displayed excellent selectivity in Congo red detection. More importantly, the regular change of fluorescence color made it possible for visualization determination of Congo red. Coupled with satisfactory recovery tests, this as-developed Cu NCs@PP had prospective future in practical application.
研究领域:
分析化学
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环境科学
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材料科学
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产品关联
DOI
PubMed
高影响因子
Materials Today Chemistry
·
2023
·
IF 7.3
Jing Jia,Hongliang Wang,Ruxia Quan,Shaomin Shuang,Zhifang Wu,Sijin Li
A novel fluorescent and smartphone-assisted colorimetric dual-mode sensor is constructed for Ag + monitoring based on orange-red emitting carbon dots (or-CDs). The as-synthesized or-CDs possess strict excitation independence and show specific response to Ag + . Ag + can induce fluorescence quenching of the or-CDs through dynamic quenching characteristic. The quenching efficiency and Ag + concentration show good linear relationships in the ranges of 0.8–10 μM and 10–100 μM with the limit of detection (LOD) down to 56 nM. More interestingly, these phenomena are accompanied by visible color conversion (red-brown) under the sunlight. So, we develop a portable smartphone-assisted colorimetry for Ag + monitoring via the red-green-blue (RGB) analysis with the linear range of 10–80 μM and LOD of 0.78 μM. Furthermore, the or-CDs have realized the monitor of Ag + in human serum and the Fenhe River with good recoveries (96.37–103.20%) and relative standard deviations (RSDs, <3%) by fluorescence and smartphone-based RGB analysis.
研究领域:
分析化学
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环境科学
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产品关联
DOI
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2022
·
IF 12.545
Xuecheng Zhu,Ying Zhang,Luxuan Han,Huilin Liu,Baoguo Sun
Quantum confinement (QC) effect-related materials have been extensively studied as photoluminescent probes for agricultural, food, and environmental analyses, with the advantage of simple-to-synthesize, reusable, nontoxic, and environmentally friendly. Herein, we propose a strategy to dimerize aromatic cyclo-dipeptides, namely cyclo-ditryptophan (cyclo-WW), cyclo-diphenylalanine (cyclo-FF), and cyclo-dihistidine (cyclo-HH), into quantum dots as basic building blocks for the self-assembly of QC supramolecular structures with excellent photoluminescent properties in aqueous solutions. In particular, through coordination with Zn(II), the bandgap can be tuned to change the photo-absorption and luminescence properties of the cyclo-dipeptide-based QC assemblies. The fluorescence quantum yield of cyclo-WW+Zn(II) was 16.9%. Such a good luminous effect makes it applicable to the detection of LC . A good linear relationship between fluorescence response of cyclo-WW+Zn(II) and LC concentration was observed in the range of 5–350 μg/L, with a low limit of detection of 2.9 μg/L and good spiked recovery of 90.72%–104.3%. A visual platform using the cyclo-WW+Zn(II)-based photoluminescent hydrogel and smartphone-assisted sample-to-answer analyzer were developed, which showed good responsiveness to LC. The developed fluorescence method , validated using traditional HPLC, is a biocompatible alternative for the rapid detection of trace pollutants with the advantages of portability and simple operation.
研究领域:
分析化学
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环境科学
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材料科学
✓ 已验证
DOI
高影响因子
TALANTA
·
2025
·
IF 6.1
Xiaodan Qi,Shengnan Zhang,Zhifei Wang,Han Zhang,Lianghui Ma,Lihua Jin,Yehua Shen
The emerging field of nanozymes has introduced unprecedented opportunities and challenges for activated charcoal materials derived from biomass waste. By incorporating specific nanostructures or elements, it is possible to overcome the limitations of traditional activated charcoal, such as insufficient catalytic active sites and poor electron transfer efficiency, thereby unlocking its full potential for various applications. In this study, we successfully synthesized trace Fe-doped activated charcoal (Fe-AC) with a graphene-like structure from biomass waste. The Fe atoms were uniformly dispersed on the activated charcoal support, which possessed a high surface area. This not only significantly increased the number of catalytic active sites but also enhanced electron transfer efficiency, substrate mobility, and collision probability. Compared to pristine activated charcoal, the synthesized Fe-AC exhibited multiple enzyme-mimetic activities, including oxidase-like, peroxidase-like, and catalase-like activities. By leveraging its peroxidase-like activity in conjunction with nitrite-specific diazotization reactions, we developed a portable, smartphone-assisted, on-site ratiometric colorimetric hydrogel sensor for nitrite detection. Utilizing smartphone-based digital imaging, this sensor enabled the quantitative analysis of nitrite at concentrations ranging from 1 to 200 μmol/L, with a detection limit as low as 1 μmol/L. The approximate range of hazardous nitrite concentrations could be easily identified with the naked eye, and the proposed strategy was successfully applied to real sample analysis. This sensor not only maximizes the utilization of waste resources, thereby reducing production costs, but also offers greater economic feasibility and environmental sustainability. Given these advantages, it holds promise for broader applications in various fields.
研究领域:
材料科学
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环境科学
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食品科学
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产品关联
DOI
PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2024
·
IF 4.3
Xiupei Yang,Xiaofang Chen,Hanyu Yang,Yuxiu Fan,Ling Jiang,Feng Huo
With the development of electronics, electroplating, printing, and dyeing industries, environmental pollution caused by hexavalent chromium (Cr(VI)) has become increasingly prominent. Skin contact with Cr (VI) can cause allergies or genetic defects, and inhalation can cause cancer, which is a lasting danger to the environment and the human body. Developing effective strategies to monitor Cr(VI) in environmental water or industrial wastewater can evaluate the degree of water pollution and risk warning, thus helping to prevent the spread of Cr(VI) pollution, promote the protection of water resources and the ecological environment, and ensure human safety and sustainable development. On the basis of the regulation of dopamine, boron-doped zinc single-atom nanozymes (Zn/B-NC SAzymes) with three-dimensional nanoflower morphology were controlled in this work. The introduction of B in Zn/B-NC SAzymes and the high metal loading of Zn (6.5 wt%) led to the formation of more active sites, resulting in the material showing excellent enzyme-like activity. H 2 O 2 decomposed to generate superoxide radicals under the catalysis of Zn/B-NC SAzymes, which then oxidized the substrate 3,3′,5,5′-tetramethylbenzidine (TMB) to generate blue oxTMB. When Cr(VI) was introduced into the sensor system, the color of blue oxTMB is deepened, and the colorimetric method of Cr(VI) was constructed. The linear range is 0.2–40 μM, LOD is 59 nM, and the visual detection of Cr (VI) is performed with the aid of the smartphone. This work not only provides experimental and theoretical guidance for understanding the active centers of Zn-SAzymes and their catalytic processes, but also provides a promising and alternative detection strategy for the rapid and even visual on-site detection of Cr(VI) in aquatic environments, which is of great significance for the control of Cr(VI) pollution in the environment and industrial wastewater.
研究领域:
环境科学
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材料科学
·
生物化学
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产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Xinyu Han,Jihong Zhou,Yunjie Li,Yuhan Zhao,Yanfei Li,Yingjie Hua,Taowen Dong,Fang Chai
An efficient and readable sensor is desirable for food safety and diagnosis. Herein, a homogeneous mimicking enzyme was constructed by encapsulating polyoxometalate (NH₄)₃[FeMo₆O₁₈(OH)₆]·6H₂O (FeMo 6 ) into the covalent organic framework (FeMo 6 @COF). Coordinating the spatial confinement effect of COF, FeMo 6 exhibited superior peroxide-like activity to catalyze H 2 O 2 to •O− 2, which achieved the “on-off” consecutive sensing of H 2 O 2 and AA via a readable colorimetric mode, with the limit of detection (LOD) at 30 μM and 0.35 μM, respectively. A convenient smartphone assistant platform was established and realized rapid, portable, visual monitoring of AA with LOD of 0.06 μM, and satisfied recoveries with 96.88–104.65 % in human serum and 98.37–107.61 % in commercial beverages. Furthermore, a logic gate circuit was designed to illustrate the potential utilization of combining the intelligent facilities with the experiment. This strategy provides efficient, swift, convenient sensor FeMo 6 @COF with great potential contribution in food safety and diagnosis.
研究领域:
生物传感器
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食品安全
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医学诊断
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产品关联
DOI
PubMed
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
·
2024
·
IF 8.2
Lian Xia,Feng Luo,Xiaojuan Niu,Yue Tang,Yuangen Wu
Pb(II) is a prevalent heavy metal ion classified as a 2B carcinogen. Excessive intake of Pb(II) in the human body can damage the central nervous system, kidneys, liver, and immune system, leading to permanent brain damage, anemia, and cancer. Colorimetry can be applied to rapidly determine Pb(II) residues, but there are still many challenges in the accuracy and sensitivity of detection. Based on the inhibitory impact of Pb(II) on the oxidase-like activity of octahedral silver oxide (Ag 2 O), a colorimetric sensor with smartphone-assisted analysis for the Pb(II) detection was first developed. Herein, it has been found that Pb(II) can adsorb onto the surface of octahedral Ag 2 O, hindering the production of O 2 − in the reaction system. This ultimately results in the suppression of oxidase-like activity, leading to a lighter purple appearance of the colorimetric reaction solution. The sensor exhibits a high degree of sensitivity and a limit of detection (LOD) for Pb(II) was calculated as 2.2 μg L −1 . Hence, the developed colorimetric sensor with high sensitivity, excellent specificity, and high tolerance to sodium ions is hopeful to have practical applications in Pb(II) detection in environmental water samples. Moreover, the sensor will provide a novel strategy for heavy metal ion detection and other substances.
研究领域:
环境科学
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分析化学
·
毒理学
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产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Yuxin He,Hecun Zou,Xinhui Jiang,Yanrui Wei,Siqiao Li,Tong Wu,Zhengwei Zhang
Foodborne residue of carbendazim (CBZ) poses a major threat to human health. Here, we rationally designed a smartphone-assisted fluorescent sensor based on bimetallic-organic framework (Eu/Tb-MOF) for ultrasensitive and visual monitoring of CBZ. The Eu/Tb-MOF nanorods fabricated using Eu 3+ /Tb 3+ as metal nodes and homobenzoic tricarboxylic acid (H 3 BTC) as organic ligand exhibit superior optical properties. After adding CBZ, the strong orange fluorescence of Eu/Tb-MOF nanorods was suppressed by the inner filter effect (IFE). The linear ranges of the fluorescent sensor were 0.01–15 and 15–80 µg/mL, with a detection limit as low as 7.09 ng/mL. The analyses of CBZ residue in tomato and orange samples showed satisfactory recoveries of 99.32 %–101.97 % and low relative standard deviations of 0.87 %–3.44 %., verifying the practicality of the probe for CBZ. Notably, a simple and portable smartphone-assisted sensing platform based on the Eu/Tb-MOF nanorods was successfully constructed for quick, visual, and real-time monitoring of CBZ residue. This work provides an efficient onsite analytical method for assessment and warning-early of CBZ to safeguard food quality
研究领域:
食品安全
·
分析化学
·
光学传感
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）