ACS Applied Polymer Materials
·
2024
·
IF 4.4
Xuan Du,Xin Liu,Yaxuan Cao,Qin Zhang,Guanghui Gao
Smart hydrogels have attracted considerable attention as smart window materials. However, the existing gel-based smart windows are often unable to be applied to humid environments due to their extreme swelling in aquatic environments. Herein, a nucleobase-inspired water-resistant adhesive is successfully designed and cleverly applied in smart windows. The adhesive exhibits durable and robust adhesion in various aquatic environments, including water, seawater, physiological saline, NaCl solutions, and a wide range of pH solutions (pH = 1–10). The adhesive can maintain high adhesive strength (∼0.8 MPa) in different harsh water environments for up to six months. Remarkably, the adhesive can be directly brushed onto surfaces of various shapes and substrates for information encryption and smart windows. The smart windows not only display stable and recyclable transparency changes triggered by solvents but also impart ordinary brittle glass with excellent impact resistance for effective stress protection. The water-resistant adhesives exhibit promising applications in underwater sealing, underwater repairing, underwater electronic devices, and underwater soft robots. It is anticipated that the strategy of water-resistant adhesive coatings will offer a broad perspective for the advancement of next-generation smart windows.
研究领域:
材料科学
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化学工程
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生物医学工程
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产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2024
·
IF 8
Mengyao Qi,Yi Ke,Yifei Li,Peng Li,Huakuo Zhou,Xia Zhang,Jieshi Chen,Jun Meng
Hyaluronidase (HAase), is a naturally occurring glycosidase with the ability to break down glycosidic bonds within hyaluronic acid (HA) chains. In this paper, we propose a portable smartphone and Surface-enhanced Raman scattering (SERS) dual-mode sensor based on Au@Pt nanozyme coated with HA hydrogel to realize sensitive detection of HAase. Au@Pt nanozyme has excellent peroxidase-like activity, oxidase-like activity and catalase-like activity under acidic conditions. When HAase is present, the hydrogel structure of HA was hydrolyzed and gradually released Au@Pt nanozyme. The released Au@Pt nanozyme is used to catalyze the hydrogen peroxide system, so that 3,3′,5,5′-tetramethylbenzidine (TMB) can be oxidized into blue 3,3′,5,5′-tetramethylbenzidine (TMB ox ). Therefore, based on the above strategies, a dual-mode sensing platform for HAase detection by smartphone and SERS was established. The linear range of the dual-mode sensor platform are 2–30 U/mL and 2–80 U/mL, and the detection limits are 1.0386 U/mL and 0.004 U/mL, respectively. The dual-mode smartphone and SERS sensor platform, a combination of smartphone and Raman spectrometer, is successfully further applied to biological urine samples. This portable dual-mode sensor based on intelligent hydrogel coated nanozyme not only opens up a new way for instant detection, but also has potential applications in clinical diagnosis.
研究领域:
生物化学
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医学诊断
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纳米技术
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产品关联
DOI
高影响因子
Food Chemistry-X
·
2025
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IF 8.2
Lu Mu,Jingran Bi,Haixin Zhao,Jinlong Li,Hong-Man Hou,Gong-Liang Zhang,Hongshun Hao,Lin Zhou
Packaging plays a pivotal role in preserving food quality throughout processing and storage. This study developed a smart hydroxypropyl methylcellulose- κ-carrageenan- gelatin (H-K-G-B) film containing blueberry anthocyanins (BA) for freshness monitoring. The incorporation of BA significantly enhanced the film's antioxidant properties, with DPPH and ABTS radical scavenging capacities reaching 82.92 % and 86.44 %, respectively. The mechanical strength of H-K-G-B film was satisfactory, achieving tensile strength of 5.85 MPa and Young's modulus of 24.05 MPa, along with superior UV–vis light barrier performance. The H-K-G-B film exhibited high NH 3 sensitivity at 32.79 % and distinct color changes with pH response in alkaline environments (R 2 = 0.9502), which was successfully applied in salmon spoilage indication. Moreover, based on the significantly correlations (R 2 > 0.90) between chromatic parameters and quality parameters, including pH, TVB-N, and TBARS, a smartphone-based visual detection platform for real-time food freshness indication was established. So, this work provides a scientifically validated solution for intelligent food packaging.
研究领域:
食品科学
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材料科学
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产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Lingqi Quan,Zhiqi Wang,Yu Zhong,Yiqiang Wu,Hui Zhao,Yan Mi,Fangchao Cheng
The potential ability of photochromic hydrogel as smart response material is determined by its coloration and fading speed. However, it is still a huge challenge to improve both the coloration and fading speed simultaneously. This paper presents the successful development of robust hydrogels with fast photoresponse and water-driven ultra-fast fading speed through the implementation of a dual-network preparation strategy. In the dual-network hydrogel, sodium tungstate contributed to its discoloration and crosslink. The obtained hydrogel exhibited fast photochromic response within 20 s under visible light irradiation. In addition, the photochromic response was achieved in 30 s under actual sunlight irradiation. Particularly, rapid fading of photochromic hydrogels was achieved by applying deionized water while leaving it naturally for 90 s. Furthermore, the simulated house experiments showed that the use of this hydrogel as smart glass could decrease the indoor temperature by about 5 °C. The photochromic hydrogel in this paper possesses excellent reversible repeatability, flexibility and foldability, and it exhibits promising potential for use in flexible information storage devices, visual displays and artificial intelligence systems, smart windows and other applications.
研究领域:
材料科学
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光电技术
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环境科学
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纳米技术
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产品关联
DOI
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2022
·Vol. 32
·期 28
·2201510
·
IF 19.924
Yue Liu,Xufeng Zhou,Hui Yan,Zhengfeng Zhu,Xiang Shi,Yahui Peng,Lin Chen,Peining Chen,Huisheng Peng
Memristors with an intrinsic crossbar structure and high computing capability offer promising opportunities for the flexible information-processing component that can well integrate with the interwoven structure of electronic textiles. However, it remains difficult to achieve uniform inorganic memristive layer at nanometer thickness on the curved surface of fiber electrode, thus hindering the applications of textile memristors. Here, a high-performing and reliable textile memristor made of robust Pt/CsPbBr 3 fiber through an electric-field-assisted assembly method is reported. The textile memristor exhibits a cycle to cycle variation of less than 8% and an average set voltage of ≈ 0.16 V, which is lower than that of the majority of planar metal-oxide memristors. The flexible and mechanically robust Pt/CsPbBr 3 fibers are woven into a scalable textile memristor array with good device-to-device reproducibility. This textile memristor can be seamlessly integrated with textile electronics toward a smart clothes system to accurately process complicated physiological information, providing an effective interactive interface for intelligent healthcare.
研究领域:
材料科学
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电子工程
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纺织工程
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生物医学工程
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产品关联
DOI
高影响因子
Infectious Diseases of Poverty
·
2021
·Vol. 10
·期 1
·1-12
·
IF 4.388
Yang Shi-Jie,Xiao Ning,Li Jing-Zhong,Feng Yu,Ma Jun-Ying,Quzhen Gong-Sang,Yu Qing,Zhang Ting,Yi Shi-Cheng,Zhou Xiao-Nong
Background As a neglected cross-species parasitic disease transmitted between canines and livestock, echinococcosis remains a global public health concern with a heavy disease burden. In China, especially in the epidemic pastoral communities on the Qinghai-Tibet Plateau, the harsh climate, low socio-economic status, poor overall hygiene, and remote and insufficient access to all owned dogs exacerbate the difficulty in implementing the ambitious control programme for echinococcosis. We aimed to design and implement a remote management system (RMS) based on internet of things (IoT) for control and surveillance of echinococcosis by combining deworming devices to realise long-distance smart deworming control, smooth statistical analysis and result display. New methods and tools are urgently needed to increase the deworming coverage and frequency, promote real-time scientific surveillance, and prevent transmission of echinococcosis in remoted transmission areas. Methods From 2016 to 2019, we had cooperated and developed the smart collar and smart feeder with the Central Research Institute of Shanghai Electric Group Co., Ltd. (Shanghai, China) and Shenzhen Jizhi Future Technology Co., Ltd. (Shenzhen, China). From September 2019 to March 2020, We had proposed the RMS based on IoT as a novel tool to control smart deworming devices to deliver efficient praziquantel (PZQ) baits to dogs regularly and automatically and also as a smart digital management platform to monitor, analyse, and display the epidemic trends of echinococcosis dynamically, in real time in Hezuo City, Gannan Tibetan Autonomous Prefecture, Gansu Province, China. Starting from January 2018, The RMS has been maintained and upgraded by Shanghai Yier Information Technology Co., Ltd (Shanghai, China). The database was based on MySQL tools and the Chi-square test was used to probe the difference and changes of variables in different groups. Results The smart collars are fully capable of anti-collision, waterproof, and cold-proof performance, and the battery’s energy is sufficient, the anti-collision rate, water-proof rate, cold-proof rate and voltage normal rate is 99.6% (521/523), 100.0% (523/523), 100.0% (523/523) and 100.0% (523/523), respectively. The RMS can accurately analyse the monitoring data and parameters including positive rates of canine faeces, and the prevalence of echinococcosis in the general population livestock, and children. The data of dogs deworming and surveillance for echinococcosis is able to be controlled using RMS and has expanded gradually in townships to the whole Hezuo region. The automatic delivering PZQ rate, collar positioning rate, deliver PZQ reminding rate, and fault report rate is 91.1% (1914/2102), 92.1% (13 580/14 745), 92.1% (1936/2102) and 84.7% (1287/1519), respectively. After using the RMS from 2019, the missing rate of monitoring data decreased from 32.1% (9/28) to 0 (0/16). A total of 48 administrators (3, 3, 8, 11, 23 at the provincial, municipal, county, township, village levels, respectively) participated in the questionnaire survey, with 93.8% of its overall satisfaction rate. Conclusions The existing difficulties and challenges in the way of prevention and control for echinococcosis can partially be resolved using the innovative, IoT-based technologies and tools. The proposed RMS advance the upgrade of existing manual prevention and control models for echinococcosis, especially in the current ongoing COVID-19 pandemic, as social distance and community blockade continue. Graphic abstract
研究领域:
公共卫生
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兽医学
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远程医疗
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传染病学
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科技与医疗
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Xudong Shi,Zhijian Wang,Jingze Guo,Heyan Guo,Lin Wang,Tingrui Sun,Shiyao Wang,Ying Zhou,Shuangli Xiong,Xing Li,Qiujin Zhu,Yisheng Chen
Package materials integrated with visible sensors straightforwardly indicating the freshness is shaping as a new generation package mode for food storage and logistic. In this study, a colorimetric sensor array (CSA) based on 12 pH-responsive indicators was precisely designed and prepared using drop-on-demand printing. The variation of CSA fingerprint dependent on the volatile organic compounds (VOCs) associated with meat spoilage can be easily documented with a smartphone, which was further quantified by evaluating the image pixel. It was demonstrated that the obtained CSA exhibits outstanding uniformity, stability (ΔE < 5), selectivity and reproducibility (<3.2 %). The detection limits for ammonia (NH 3 ), dimethylamine (DMA), and trimethylamine (TMA) were determined to be 0.11 ppm, 0.13 ppm, and 0.15 ppm, respectively. Besides, outstanding discernment capability toward the spoilage status in terms of meat type and storage time, was experimentally evidenced, by using chemometric tools including principal component analysis (PCA) and hierarchical cluster analysis (HCA). Then, the performance of the CSA was validated by benchmarking with official standard methods stipulated to evaluating meat freshness (pork and shrimp). A strong correlation ( R 2 = 0.991) was observed between the CSA fingerprints and the measurements of total volatile basic nitrogen (TVB-N), demonstrating that the CSA might be a powerful tool for online freshness monitoring.
研究领域:
食品科学
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传感技术
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化学计量学
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产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF TECHNOLOGY AND DESIGN EDUCATION
·
2024
·Vol. 34
·期 5
·1687-1704
·
IF 2
Cai Lu
Based on Folk theory, Media Equation, and AI literacy research, the study constructed an interview outline and selected 72 students in 4th and 5th grade in three primary schools located in the Minhang and Putuo districts of Shanghai (two in the Minhang district and one in the Putuo district) as the study participants for focus group interviews. The study found that the availability of voice interaction is an essential basis for children to judge the level of intelligence of a machine; additionally, chatting is also the starting point for young children to build a close relationship with AI. Although AI cannot replace their friends, it can become a friend to them. While children expect the future of AI to be beyond the current level of intelligence and emotion and to enable the full use of machines in multiple scenarios and various fields, they are also concerned about issues such as privacy breaches that devices may cause in the future and believe that technology should not develop outside of human control.
研究领域:
教育心理学
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人机交互
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儿童发展研究
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DOI
高影响因子
Frontiers in Education
·
2024
·
IF 1.9
Yi Yan,Wei Sun,Xiufeng Zhao
The unveiling of ChatGPT 4o by OpenAI, a multimodal large language model powered by Generative Artificial Intelligence (GenAI), has injected interest and incited debate throughout the echelon of education institutions regarding its prospective benefits and drawbacks. Nonetheless, investigations into the learners’ perceptions of GenAI use in learning English as a Foreign Language (EFL) remain markedly insufficient. The study adopts an explorative stance and aims to explore the attitudes and perceptions of Chinese EFL learners toward GenAI use in language learning through the application of metaphor analysis. Data were collected from 281 EFL students of varying majors in four key universities across China by completing a sentence using metaphors to elicit their attitudes and perceptions toward GenAI use in language learning. Through qualitative analysis of metaphorical constructs, including HUMANS, TOOL/MACHINE, BRAIN, RESOURCES, FOOD/DRINK, and MEDICINE metaphors, the study unveils a spectrum of attitudes toward GenAI. While some language learners perceived GenAI as supportive, helpful, and intelligent, others expressed concerns about over-reliance and potential loss of critical thinking skills. The findings underscore the importance of considering learners’ diverse attitudes and beliefs toward GenAI use and application in language learning pedagogy. The implications of these findings for the future integration of GenAI in language education are discussed, complemented by recommendations for further research and pedagogical practice.
研究领域:
应用语言学
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外语教学
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教育技术学
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二语习得
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人工智能教育应用
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学习科学
✓ 已验证
DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2024
·
IF 6.7
Mengxin Zhang,Yingyu Zhang,Xianwei Zhang,Kangbo Liu,Lifeng Li,Zhidan Yu,Jingya Yuan,Wancun Zhang
Due to the potential off-tumor signal leakage and limited biomarker content, there is an urgent need for stimulus-responsive and amplification-based tumor molecular imaging strategies. Therefore, two tetrahedral framework DNA (tFNA-Hs), tFNA-H1AP, and tFNA-H2, were rationally engineered to form a polymeric tFNA network, termed an intelligent DNA network, in an AND-gated manner. The intelligent DNA network was designed for tumor-specific molecular imaging by leveraging the elevated expression of apurinic/apyrimidinic endonuclease 1 (APE1) in tumor cytoplasm instead of normal cells and the high expression of miRNA-21 in tumor cytoplasm. The activation of tFNA-H1AP can be achieved through specific recognition and cleavage by APE1, targeting the apurinic/apyrimidinic site (AP site) modified within the stem region of hairpin 1 (H1AP). Subsequently, miRNA-21 facilitates the hybridization of activated H1AP on tFNA-H1AP with hairpin 2 (H2) on tFNA-H2, triggering a catalytic hairpin assembly (CHA) reaction that opens the H1AP at the vertices of tFNA-H1AP to bind with H2 at the vertices of tFNA-H2 and generate fluorescence signals. Upon completion of hybridization, miRNA-21 is released, initiating the subsequent cycle of the CHA reaction. The AND-gated intelligent DNA network can achieve specific tumor molecular imaging in vivo and also enables risk stratification of neuroblastoma patients.
研究领域:
生物化学
·
分子生物学
·
医学影像学
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产品关联
DOI
PubMed
高影响因子
Frontiers in Cell and Developmental Biology
·
2025
·
IF 4.3
Cheng Han,Shanshan Fu,Dachao Tang,Yuting Chen,Dan Liu,Zihao Feng,Yujie Gou,Chi Zhang,Weizhi Zhang,Leming Xiao,Jiayi Zhang,Cong Yi,Yu Xue,Di Peng
In Saccharomyces cerevisiae , Atg1 is a core autophagy-related (Atg) protein kinase (PK) in regulating macroautophagy/autophagy, by physically interacting with numerous other proteins, or by phosphorylating various substrates. It is unclear how many Atg1-interacting partners and substrates are also involved in regulating autophagy. Here, we conducted transcriptomic, proteomic and phosphoproteomic profiling of Atg1-dependent molecular landscapes during nitrogen starvation-triggered autophagy, and detected 244, 245 and 217 genes to be affected by ATG1 in the autophagic process at mRNA, protein, and phosphorylation levels, respectively. Based on the Atg1 interactome, we developed a novel artificial intelligence (AI) framework, inference of autophagy regulators from multi-omic data (iAMD), and predicted 12 Atg1-interacting partners and 17 substrates to be potentially functional in autophagy. Further experiments validated that Rgd1 and Whi5 are required for bulk autophagy, as well as physical interactions and co-localizations with Atg1 during autophagy. In particular, we demonstrated that 2 phosphorylation sites (p-sites), pS78 and pS149 of Whi5, are phosphorylated by Atg1 to regulate the formation of Atg1 puncta during autophagy initiation. A working model was illustrated to emphasize the importance of the Atg1-centered network in yeast autophagy. In addition, iAMD was extended to accurately predict Atg proteins and autophagy regulators from other PK interactomes, indicating a high transferability of the method. Taken together, we not only revealed new autophagy regulators from the Atg1 interactome, but also provided a useful resource for further analysis of yeast autophagy.
研究领域:
分子生物学
·
生物信息学
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产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Jiahao Zhang,Shengyu Bai,Zhongqi Li,Guanyao Gu,Hucheng Wang,Lai Wei,Xun Sun,Fuzhen Xuan,Xuhong Guo,Yiming Wang
Poly( N -isopropylacrylamide) (PNIPAm) is widely used for smart materials and devices owing to its thermoresponsiveness. Here we demonstrate how PNIPAm can be geared to show reversible phase transition in response to light rather than temperature through a simple signal transformation strategy. This strategy does not require the polymer to be tediously modified with any photoresponsive moieties, offering a new approach towards remote-controlled smart objects. Our concept is achieved using a photoacid and simple PNIPAm-based copolymers. Upon switching on/off light, the photoacid releases/captures a chemical signal which can reversibly change the lower critical solution temperature (LCST) of the copolymers, thereby resulting in a fast (<0.5 min) and reversible phase transition of the copolymer without changing the ambient temperature. Thereon, a series of light-controlled dynamic patterns and conceptually smart soft actuators composed of the copolymers are fabricated. Such a signal transformation strategy enabling PNIPAm photoresponsiveness may boost the development of new non-contact smart objects with adaptive responsiveness.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）