Journal of Energy Storage
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2020
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IF 3.762
Yi Zhao,Xuelai Zhang,Xiaofeng Xu,Shihua Zhang
According to the temperature requirements of pharmaceutical cold chain logistics, the aim is to develop phase change materials with a phase transition temperature of 2 °C ~ 8 °C. In this study, a mixed solution of tetradecane (TD) and lauryl alcohol (LA) was selected as the base liquid. In view of the low thermal conductivity of organic phase change materials, expanded graphite (EG) was added to TD-LA to improve the thermal conductivity. This study also developed a new type of cold storage equipment for vaccine, which can monitor the temperature of the vaccine in real time on the user's mobile phone. The cold storage equipment is equipped with a special cold storage box of vaccine. The vaccine reagent tube can be placed in the storage hole of the cold storage box. It can ensure that the cold storage agent in the cold storage box releases and transmits the cold quantity more evenly among the goods. Coupling the developed low temperature phase change material with the cold storage equipment can ensure that the vaccine is always in the required low temperature environment in the process of transportation for a long time to ensure its quality.
研究领域:
材料科学
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生物医药工程
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Zhengting Xiao,Dongcai Shen,Kai Guo,Guangci Li,Wentai Wang,Xuebing Li,Song Chen,Chunhu Li
Cu-based catalysts were synthesized utilizing the ZnAl 2 O 4 spinel as supports for the selective hydrogenation of methyl stearate to stearyl alcohol. The presence of Zn atoms inhibited the agglomeration of the particles of Cu species in the reduction process, promoting the distribution of Cu species on the catalyst surface, which will enhance hydrogen activation and selective hydrogenation activity. DFT calculations show that the bond energies of the C-O bonds on both sides of the ester group decrease with the adsorption of the ester molecule onto Cu + species, and the C-O bond energy on the methyl side is lower than that on the carbonyl side. However, because the carbonyl carbon is more susceptible to nucleophilic attack, the C-O bond on the carbonyl side is more easily broken. In addition, the oxygen vacancies of the supports promote hydrogen spillover and the adsorption and activation of ester groups, which further enhance the selective hydrogenation activity of the catalyst on methyl stearate.
研究领域:
催化化学
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材料科学
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理论计算
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DOI
高影响因子
JOURNAL OF CHEMICAL THERMODYNAMICS
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2013
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IF 2.297
Yang Lu,Tongfan Hao,Yan Zhou,Juan Han,Zhenjiang Tan,Yongsheng Yan
The binodal data for the systems containing the POELE10 and KC 6 H 11 O 7 /K 2 C 2 O 4 /K 3 C 6 H 5 O 7 were determined at the T = (288.15, 298.15, 308.15) K. The three experiential equations were used to fit the binodal data and they achieved the satisfactory fitting effect. The effect of salt type on the phase-seperation ability of salt was studied. It was found that the phase-seperation ability of the salt with the higher valence anion is stronger than that with lower valence anion, namely, the order of the phase-seperation ability for the investigated salts is potassium citrate > potassium oxalate > potassium gluconate, which is also validated by the effective excluded volume (EEV). The (liquid + liquid) equilibrium data for the studied systems were determined and correlated by using the Pitzer–Debye–Hückel equation and Chen-NRTL model along with the Flory–Huggins equation, and good agreement was obtained with using these thermodynamic models.
研究领域:
化学工程
·
物理化学
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DOI
高影响因子
TENSIDE SURFACTANTS DETERGENTS
·
2019
·Vol. 56
·期 3
·244-251
·
IF 0.748
Yaning Shi,Yonghong Zhao,Guangliang Zhang,Qingbin Dong
Lauryl phosphate monoester was synthesized from the starting materials lauryl alcohol and phosphoric acid without catalysts. Subsequently, the crude product was purified by recrystallization and characterized by Fourier transform infrared (FT-IR) and nuclear magnetic resonance ( 31 P-NMR). From the results, it was apparent that the synthesized material was the desired target product. Lauryl monoester potassium phosphate reduced the surface tension of water to 25.08 mN/m at a critical micelle concentration (CMC) of 0.569 mmol/L. It showed a low contact angle and had a low surface tension, indicating a good hydrophilicity. Lauryl monoester potassium phosphate also showed excellent antistatic properties, however its emulsifying ability was not good. The size of the aggregates of lauryl monoester calcium phosphate in aqueous solution was 220 nm and their morphology was spherical.
研究领域:
化学合成
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材料科学
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表面化学
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DOI
高影响因子
JOURNAL OF MOLECULAR LIQUIDS
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2024
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IF 5.3
Qiang Zhang,Xu Li,Jinxiang Dong
Despite significant breakthroughs that have been made in the application performance of traditionally distributed Guerbet alcohol ethoxylates (GAEO), research on the characteristics of their narrow distribution products remains relatively limited. Herein, a series of hydrophilic and hydrophobic nonionic surfactants have been synthesized via the ethoxylation of 2-butyl-octanol with ethylene oxide. Ca(OAc) 2 was employed as a narrow distribution (NRD) catalyst, while KOH served as a broad distribution (BRD) catalyst. The synthesized products were characterized using Fourier-transform infrared (FT-IR), 1 H and 13 C nuclear magnetic resonance ( 1 H, 13 C NMR) spectroscopy. In addition, a comprehensive assessment of the physicochemical and surface properties of the NRD GAEO surfactants was conducted through systematic investigations. The results were then compared to conventionally distributed GAEO surfactants. The study has demonstrated that NRD GAEO surfactants exhibited lower critical micelle concentration (CMC) values, which have the higher efficiency of the surfactant application. In addition, the NRD products have superior wettability performance, reduced foaming capacity in foam properties, and improved rapid defoaming capacities. In regarding their other properties, they closely mirrored the performance of BRD products. These findings will contribute to a comprehensive understanding of the properties of NRD ethoxylates and have substantial practical implications in optimizing personal care and household cleaning products.
研究领域:
化学
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材料科学
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表面活性剂技术
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DOI
高影响因子
Materials Advances
·
2022
·Vol. 3
·期 5
·2505-2514
·
IF 0
Wenzhu Yin,Dechun Xuan,Bihua Deng,Mingxu Zhou,Fang Ma,Jinqiu Zhang,Yu Lu
Adjuvants have proven to be integral components in most vaccines for promoting appropriate immune responses at both innate and adaptive levels. Imiquimod (IMQ, R837), an agonist for Toll-like receptors 7 (TLR7), is a potent molecular activator of the innate immune system and has been developed as an adjuvant for immunotherapy. However, due to its pharmacokinetic profile, IMQ may induce strong local and systemic inflammatory reactions and is poorly tolerated. To overcome these hurdles, herein, we conjugate IMQ and lauryl alcohol (LA) to the backbone of biodegradable poly (γ-glutamic acid) (γ-PGA) to prepare an amphiphilic polymer (shortened to γ-PGA-IMQ-LA) with improved stability and biodistribution of IMQ. In order to investigate the distribution of the amphiphilic polymer in vitro and in vivo, fluorescein was grafted to the lateral chain to synthesize fluorescent-labeled γ-PGA-IMQ-LA-FL (shortened to FIP). The novel amphiphilic FIP polymer was characterized via1H NMR, FI-IR, UV-vis, fluorescence spectra and zeta potential. Using ovalbumin (OVA) as a model antigen and FIP as an adjuvant for immunization, the formulations of FIP + OVA in different dosages could significantly promote the production of OVA-specific IgG in mice and prolong immune responses with acceptable safety.
研究领域:
免疫学
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药剂学
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聚合物化学
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生物医学工程
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DOI
危险品化学品经营许可证（带存储）