INDUSTRIAL CROPS AND PRODUCTS
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2024
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IF 5.6
Qiulian Liu,Weihua Li,Xiaolong Qiao,Haiguang Zhao
Colloidal carbon dots (C-dots) have excellent optical properties and they have been widely used for various types of applications. Compared to the C-dots prepared using chemicals, the Biomass-derived C-dots have attracted a great of attention because of their environmental friendliness and biocompatibility. However, currently obtained C-dots using biomass have low quantum yield. In this work, we demonstrated an efficient precursor of Magnolia flower for synthesizing high-quantum yield C-dots via hydrothermal approach. High performance liquid chromatography and Bradford assay were used to analyze the compositions of the Magnolia flower, which determine the quality of the C-dots. The typical emission bands of the as-prepared C-dots cover from 400 to 550 nm at different excitation wavelengths. The C-dots synthesized using violet Magnolia flower have the QY as high as 11.9%, which is higher than that of 10.4% (white Magnolia flower), because the violet color gives the higher content of the N. The as-obtained C-dots have excitation-dependent color and high quantum yield, showing a great potential for the use of the anti-counterfeiting system.
研究领域:
材料科学
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植物学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ETHNOPHARMACOLOGY
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2023
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IF 5.4
Minzhen Xie,Siqi Gu,Yang Hong,Yan Liu,Xiaohui Rong,Wanying Lu,Heng Liu,Adnan Mohammed Algradi,Anam Naseem,ZunPeng Shu,Qi Wang
Ethnopharmacological relevance Coptis chinensis Franch. (CCF), as an extensively used traditional Chinese medicine , has therapeutic effects on Alzheimer's disease (AD), but its mechanism of action has not yet been elucidated. Aim of the study This study aims to reveal the mechanism of action of CCF via the gut-brain axis, and provide a new strategy for the clinical treatment of AD. Materials and methods APP swe /PS1ΔE9 mice were used as AD models, and were given CCF extract by intragastric administration. Barnes maze was used to test the therapeutic effect of CCF on the treatment of AD. To reveal the mechanism of action of CCF in the treatment of AD, Vanquish Flex UHPLC-orbitrap fusion lumos mass was chosen to detect endogenous differential metabolite; MetaboAnalyst 5.0 was applied to derive relevant metabolic pathways; similarly, to explore the effects of CCF on the gut-brain axis, Vanquish Flex UPLC-Orbitrap fusion lumos mass was utilized to detect the changes in the content of SCFAs in AD mice after CCF administration; the prototype components and metabolites in CCF were identified by UPLC/ESI/qTOF-MS, then their effects on Bifidobacterium breve were explored. Results CCF shortened the latency time of AD mice, improved the target quadrant ratio of AD mice, and made the maze roadmap simpler of AD mice; CCF regulated fifteen potential metabolites of AD mice, interestingly, ILA (indole-3-lactic acid) in SCFAs (short-chain fatty acids) was also included; CCF acted on histidine and phenylalanine metabolic pathways of AD mice; CCF increased the contents of acetic acid and ILA in AD mice; magnoflorine , jatrorrhizine , coptisine , groenlandicine, thalifendine , palmatine , berberine , epiberberine, hydroxylated jatrorrhizine, and 3-methoxydemethyleneberberine in CCF were detected in fecal samples of AD mice; magnoflorine, palmatrubine, 13-methylberberine, berberine, coptisine, and palmatine promoted the growth of Bifidobacterium breve. Conclusions: we have demonstrated that CCF acts on the gut-brain axis by regulating SCFAs to treat AD.
研究领域:
民族药理学
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神经科学
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药理学
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代谢组学
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中药学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）