The smart mechanical sensing technology based on mechanoluminescence (ML) has potential applications in the fields of wearable mechanical sensors and remote detection of human health due to its characteristics of non-contact, visualization, and remote signal transmission. Herein, a new strategy for multi-mode ML in the rigid and flexible medium by embedding fluoride nanocrystals (CaF2: Tb3+) in amorphous media was proposed and the intrinsic physical mechanism of energy conversion was clarified. For the rigid transparent CaF2: Tb3+ glass ceramics (GCs), without being fabricated with any special medium, recoverable trap-controlled ML can be generated under friction after X-Ray pre-irradiation. Furthermore, the ML composite device fabricated using CaF2: Tb3+ GCs powder and flexible stretchable polydimethylsiloxane (PDMS) can achieve self-recovery ML under multimode mechanical stimulation due to the induction of inorganic-organic interface triboelectrification. Finally, a rigid accurate stress detection at non-stressed point positions is designed based on the remote transmission of ML signal owing to the unique optical waveguide effect of GCs, and a flexible mechanical-sensing optical skin for real-time monitoring of human health status is realized by CaF2: Tb3+ GCs powder/PDMS composite device. This work opens up a new avenue for the realization of multi-scene stress detection based on rigid/flexible ML material.
The extracellular matrix (ECM) plays a crucial role in regulating cellular behaviors and functions. However, the impact of ECM topography on muscle cell adhesion and differentiation remains poorly understood from a mechanosensing perspective. In this study, we fabricated aligned and random electrospun polycaprolactone (PCL) nanofibers to mimic the structural characteristics of ECM. Mechanism investigations revealed that the orientation of nanofibers promoted C2C12 polarization and myogenesis through Rac-related signaling pathways. Conversely, cells cultured on random fibers exhibited spreading behavior mediated by RhoA/ROCK pathways, resulting in enhanced stress fiber formation but reduced capacity for myogenic differentiation. Our findings highlight the critical role of an ECM structure in muscle regeneration and damage repair, providing novel insights into mechanosensing mechanisms underlying muscle injury diseases.
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