NANOTECHNOLOGY
·
2023
·Vol. 34
·期 38
·385403
·
IF 3.5
Jianwei He,Xuhua Guo,Caofeng Pan,Gang Cheng,Mingli Zheng,Yunlong Zi,Hongzhi Cui,Xiaoyi Li
Infectious diseases are spreading rapidly with the flow of the world's population, and the prevention of epidemic diseases is particularly important for public and personal health. Therefore, there is an urgent need to develop a simple, efficient and non-toxic method to control the spread of bacteria and viruses. The newly developed triboelectric nanogenerator (TENG) can generate a high voltage, which inhibits bacterial reproduction. However, the output performance is the main factor limiting real-world applications of TENGs. Herein, we report a soft-contact fiber-structure TENG to avoid insufficient friction states and to improve the output, especially at a high rotation speed. Rabbit hair, carbon nanotubes, polyvinylidene difluoride film and paper all contain fiber structures that are used to guarantee soft contact between the friction layers and improve the contact state and abrasion problem. Compared with a direct-contact triboelectric nanogenerator, the outputs of this soft-contact fiber-structure TENG are improved by about 350%. Meanwhile, the open-circuit voltage can be enhanced to 3440 V, which solves the matching problems when driving high-voltage devices. A TENG-driven ultraviolet sterilization system is then developed. The bactericidal rate of this sterilization system can reach 91%, which significantly reduces the risk of disease spread. This work improves a forward-looking strategy to improve the output and service life of the TENG. It also expands the applications of self-powered TENG sterilization systems.
研究领域:
纳米技术
·
生物医学工程
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材料科学
·
公共卫生
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
·
2020
·
IF 6.551
Yuan Xie,Xi Qu,Jinyang Li,Da Li,Wei Wei,David Hui,Qiao Zhang,Fanbin Meng,Hong Yin,Xiaoling Xu,Yong Wang,Li Wang,Zuowan Zhou
Various nanostructured surfaces have been developed recently to physically inactivate bacteria, for reducing the rapidly spreading threat of pathogenic bacteria. However, it generally takes several hours for these surfaces to inactivate most of the bacteria, which greatly limits their application in the fields favoring rapid bactericidal performance. Besides, the accumulated bacteria debris left on these surfaces is rarely discussed in the previous reports. Herein we report the nanotip-engineered ZnO nanoarrays (NAs) with ultrafast physical bactericidal rate and the ability to photocatalytically remove the bacteria debris. Neither chemical (Zn 2+ or reactive oxygen species) nor photocatalytic effect leads to the ultrafast bactericidal rate, where 97.5% of E. coli and 94.9% of S. aureus are inactivated within only 1 min. The simulation analysis further supported our proposed mechanism attributing the ultrafast bactericidal activity to the great stress enabled by the uneven topography. Moreover, the re-exposure of the ZnO NAs nanotips can be achieved in only 10 min under a mild UV light source. This study not only presents an ultrafast physical bactericidal activity, but also demonstrates the potential of the recyclable and photocatalytic self-cleaning functions of theses surfaces for applications that desire rapid and sustainable bactericidal performance.
研究领域:
材料科学
·
纳米技术
·
环境科学
·
微生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
·
2023
·Vol. 24
·期 21
·15609
·
IF 5.6
Xiao Han,Yinjie Qian,Jiapeng Li,Zhongkai Zhang,Jinbo Guo,Ning Zhang,Longyu Liu,Zhiqiang Cheng,Xiaobin Yu
In order to reduce the use of fungicide and ensure food safety, it is necessary to develop fungicide with low toxicity and high efficiency to reduce residues. Azoxystrobin (AZOX), which is derived from mushrooms, is an excellent choice. However, conventional AZOX release is difficult to regulate. In this paper, a pH-responsive fungicide delivery system for the preparation of AZOX by impregnation method was reported. The Zinc metal–organic framework/Biomass charcoal (ZIF-8/BC) support was first prepared, and subsequently, the AZOX-ZIF-8/BC nano fungicide was prepared by adsorption of AZOX onto ZIF-8/BC by dipping. Gray mold, caused byBotrytis cinerea, is one of the most important crop diseases worldwide. AZOX-ZIF-8/BC could respond to oxalic acid produced byBotrytis cinereato release loaded AZOX. When pH = 4.8, it was 48.42% faster than when pH = 8.2. The loading of AZOX on ZIF-8/BC was 19.83%. In vitro and pot experiments showed that AZOX-ZIF-8/BC had significant fungicidal activity, and 300 mg/L concentration of AZOX-ZIF-8-BC could be considered as a safe and effective control ofBotrytis cinerea. The above results indicated that the prepared AZOX-ZIF-8/BC not only exhibited good drug efficacy but also demonstrated pH-responsive fungicide release.Keywords:AZOX-ZIF-8/BC;Botrytis cinerea;fungicide;nano fungicide;pH-responsive release
研究领域:
植物保护
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农业科学
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材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CELLULOSE
·
2022
·Vol. 29
·期 13
·7139-7149
·
IF 6.123
Cai Chenchen,Luo Bin,Liu Tao,Gao Cong,Zhang Wanglin,Chi Mingchao,Meng Xiangjiang,Nie Shuangxi
A variety of liquid energy exists in papermaking engineering and has not yet been developed and utilized. In addition, for the papermaking industry, the presence of slime can seriously affect the quality of the finished paper and can lead to paper breaking. The current slime control strategies cannot completely solve the problem and also have some low toxicity. In this study, a method of self-powered sterilization of cellulose fibers by using triboelectric pulsed direct current is reported. A liquid–solid triboelectric nanogenerator (L–S TENG) was used to convert the liquid energy of nanocellulose suspension into electrical energy and convert this electrical energy into pulsed direct current for self-powered sterilization of cellulose fiber. A hydrophobic coating material is used as solid triboelectric material and electrode for sterilization. Driven by L–S TENG, the electrodes exhibited an excellent sterilization rate against four microorganisms including Escherichia coli , Aspergillus niger , Candida albicans, and Klebsiella pneumoniae , which from slime in the papermaking industry. This study could provide a basic research theory for liquid energy harvesting in the papermaking industry, and also provide a new strategy for pulp sterilization. Graphical abstract
研究领域:
能源转化
·
生物工程
·
造纸工业
✓ 已验证
DOI
高影响因子
Coatings
·
2022
·Vol. 12
·期 9
·1263
·
IF 3.236
Honggang Xia,Dongbin Wang,Aixian Tian,Yingde Xu,Hao Gong,Zhaoyang Li,Jun Miao
Medical tools and implants used in clinics can be contaminated with bacteria even with disinfection treatment. To avert this situation, titanium (Ti) plates modified with a MoS2(S)–Ag3PO4coating were designed to killStaphylococcus aureus(S. aureus) andEscherichia coli(E. coli) effectively under near-infrared (NIR) light irradiation. The introduction of Ag3PO4nanoparticles (NPs) reduced the bandgap of MoS2and suppressed the recombination of the photogenerated electron–hole pairs. Therefore, Ti–MoS2(S)–Ag3PO4exhibited a higher photocatalytic performance, leading to the generation of more radical oxygen species (ROS). Furthermore, cooperating with the good photothermal performance of MoS2, the MoS2(S)–Ag3PO4coating exhibited a high antibacterial efficacy of 99.76 ± 0.15% and 99.85 ± 0.09% againstS. aureusandE. coli, respectively, for 15 min in vitro. Moreover, the MoS2(S)–Ag3PO4coating had no apparent toxicity to cells. The proposed strategy may provide new insights for rapidly eradicating bacteria on medical tools and superficial implants.Keywords:bacteria-killing;Ag3PO4;MoS2;photocatalytic;photothermal
研究领域:
材料科学
·
微生物学
·
医学工程
✓ 已验证
产品关联
DOI
高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
·
2024
·
IF 5.4
Haofeng Xiao,Shuxue Zhou
Combining with various antibacterial mechanisms is the preferred strategy to fabricate coatings with effective antibacterial performance. Herein, Cu 2 O nanoparticles and dimethyloctadecyl [3-(trimethoxysilyl) propyl] ammonium chloride, a kind of quaternary ammonium salt (QAS), were simultaneously incorporated into a moisture-curable acrylic resin in order to achieve both contact-killing and release-killing abilities for antibacterial coatings. The surface morphology, surface composition and basic properties of the coatings were thoroughly characterized. The antibacterial performance of the coatings was determined by in-vitro bacteriostatic test. Under the constant total mass fraction of antibacterial agents, both Cu 2 O and QAS content possessed the highest value on the coating surface at Cu 2 O/QAS mass ratio of 1:1, and correspondingly, the coatings reached sterilizing rate above 99 % against both E. coli and S. loihica , indicating the existence of synergistic effect between Cu 2 O and QAS. The synergistic antibacterial mechanism of the coatings involved two aspects. Firstly, the combination of contact-killing and release-killing biocides resulted in high bactericidal and antibiofilm activity against different bacteria. Further, the grafting of QAS molecules on the surface of Cu 2 O particles brought about the spontaneous migration of nanoparticles to the coating surface. The interaction between Cu 2 O and QAS also inhibited the phase separation of QAS and prolonged the release of Cu 2+ at the same time. The coatings, therefore, exhibited stable antibacterial performance at varied service conditions.
研究领域:
材料科学
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微生物学
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化学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
HORTTECHNOLOGY
·
2011
·Vol. 21
·期 5
·533-538
·
IF 0.596
Timothy Coolong,Kenneth Seebold
The effects of fungicide program and varietal resistance on the development of cucurbit powdery mildew [PM (Podosphaera xanthii)] in pumpkin (Cucurbita pepo) were tested in 2009 and 2010 in Lexington, KY. Three fungicide programs consisted of a no-fungicide control, low input (chlorothalonil), and high input (chlorothalonil alternated with myclobutanil) were applied to three varieties of pumpkin with different levels of cucurbit PM resistance. Varieties tested were Howden, Aladdin, and Camaro, which had no, moderate, and high levels of cucurbit PM resistance, respectively. There were no significant variety by fungicide program interactions for yield, number fruit per acre, and average fruit weight in both years. In 2009 and 2010, variety significantly affected yield. Yield increases corresponded to the level of cucurbit PM resistance. The high-resistance variety, Camaro, had the greatest yields in both years, while Howden, with no PM resistance, had the lowest yields. In 2010, yield significantly increased with the intensity of fungicide program. With the exception of cull percentage in 2009, there were no fungicide program by variety interactions for yield parameters. In both years, PM disease severity, characterized by the area under the disease progress curve (AUDPC), was lowest on ‘Camaro’ and highest on ‘Howden’. In 2009, unsprayed ‘Camaro’ had similar AUDPC values as ‘Aladdin’ and ‘Howden’ treated with low- or high-input fungicide programs. In 2010, unsprayed ‘Camaro’ had less disease than ‘Aladdin’ or ‘Howden’ that had received the high-intensity fungicide program. These results suggest that yields can be maintained with a minimal fungicide program when using a variety with high cucurbit PM resistant in some environments. A high-input fungicide program may be necessary to maintain yields of varieties with low cucurbit PM resistance.
研究领域:
植物病理学
·
农学
✓ 已验证
DOI
高影响因子
Biomaterials Science
·
2023
·Vol. 11
·期 10
·3589-3602
·
IF 6.6
Bo Huang,Wei Guan,Chaofeng Wang,Shuilin Wu,Zhenduo Cui,Yufeng Zheng,Zhaoyang Li,Shengli Zhu,Hui Jiang,Paul K. Chu,Xiangmei Liu
Charge transfer and separation play a critical role in the photocatalytic efficiency of photoresponsive materials and their subsequent applications. Herein, for the first time, we constructed a homo-heterostructured S–Cu–FC/CuS modified carboxymethyl cellulose (CMC) hydrogel doped with graphene oxide (GO) (S–Cu–FC/CuS/GO@CMC) through an in situ ionic complexation reaction, which exhibited enhanced photocatalytic performance under 808 nm near-infrared (NIR) light irradiation. On the one hand, photo-excited charges can rapidly transfer across the homo-heterojunction interface with copper atoms in S–Cu–FC/CuS as both donors and acceptors. On the other hand, the interface between GO and S–Cu–FC/CuS also favors the fast transfer of photogenerated charges. Hence, with the assistance of a photothermal effect, the enhanced photocatalytic performance of S–Cu–FC/CuS/GO endowed the hydrogel with robust sterilization ability for killing 99.5% S. aureus and 100.0% E. coli under 10 min NIR light irradiation. An in vivo test disclosed that this hydrogel could also accelerate the healing of bacteria-infected wounds.
研究领域:
材料科学
·
光催化
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Foods
·
2025
·Vol. 14
·期 17
·3136
·
IF 5.1
Beibei Chu,Chao Zhang,Yushen Song,Hui Zhou,Xingguang Chen,Qianhui Gu
This study aimed to investigate the effect of thermal sterilization on the volatile flavor of sauced duck necks. The study revealed that thermal sterilization significantly reduced the content of unsaturated fatty acids (e.g., oleic acid C18:1n9c) in sauced duck necks. This was accompanied by elevated thiobarbituric acid reactive substances (max 0.86 mg/100 g) and peroxide values (max 1.13 g/100 g), indicating intensified lipid oxidation. Through PLS-DA, six key differential free fatty acids distinguishing the sterilization treatment groups were identified: cis-9-tetradecadecarbonate, methyl tridecarbonate, cis-10-17-cetenoic acid, antioleic acid, cis-13-docosaenoic acid methyl ester, and lauric acid. The primary volatile flavor compounds in sauced duck necks were identified as alkenes and ethers. Post-sterilization alterations in volatile flavor profiles primarily resulted from compositional changes in alkenes, esters, and ethers within the total volatile compounds. Moreover, it was demonstrated that sterilization temperature exerted a significantly greater impact on the quality of sauced duck necks than sterilization duration. Following organoleptic evaluation, samples subjected to low-temperature prolonged sterilization (90 °C for 30 min) exhibited the highest aroma scores, establishing this protocol as the optimal thermal sterilization condition. This study is of great significance for selecting thermal sterilization conditions and maintaining meat flavor.
研究领域:
食品科学
·
食品加工
·
风味化学
·
脂质化学
·
分析化学
·
感官评价
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
·
2023
·
IF 9.8
Zhiwei Bao,Dou Wang,Yao Zhao,Ting Luo,Guilin Yang,Yuanxiang Jin
Carbendazim (CBZ) and procymidone (PRO) are two widely used fungicides in agriculture. However, there are still gaps in knowledge regarding about the potential hazards of joint exposure to CBZ and PRO in animals. Here, 6-week-old ICR mice were exposed to CBZ, PRO and CBZ + PRO for 30 days, and metabolomics were performed to discover the mechanism by which the mixture enhanced the effects on lipid metabolism. Co-exposure to CBZ + PRO elevated the body weights, relative liver weights and relative epididymis fat weights, but not in the single exposure groups. Molecular docking analysis suggested that CBZ and PRO combined with peroxisome proliferator-activated receptor (PPARγ) at the same amino acid site as the agonist rosiglitazone. The RT-qPCR and WB results demonstrated that the levels of PPARγ were higher in the co-exposure group than in the single exposure groups. In addition, hundreds of differential metabolites were discovered by metabolomics and enriched in different pathways, such as pentose phosphate pathway and purine metabolism. A unique effect, a decrease in glucose-6-phosphate (G6P) that promoted more NADPH production, was observed in the CBZ + PRO group. These results demonstrated that exposure to CBZ + PRO caused more serious lipid metabolism disorder in the liver than exposure to a single fungicide, which could provide some new insight for the toxic effects after fungicides joint exposure.
研究领域:
毒理学
·
药理学
·
代谢组学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
·
2021
·
IF 3.963
Yanan Sun,Haiping Shi,Chenxin Mao,Jianyan Wu,Chuanqing Zhang
The occurrence of bakanae disease of rice caused by the fungus Fusarium fujikuroi in Zhejiang Province has become increasingly aggravated in recent years, concomitant with the development of resistance to the widely applied fungicides , prochloraz and phenamacril. In this study, the activity of a novel succinate dehydrogenase inhibitor (SDHI) fungicide, penflufen, against different fungi was evaluated in addition to the potential of penflufen in controlling F. fujikuroi infections. Penflufen exhibited good bioactivity against F. fujikuroi , but weak activity against Fusarium spp. and other investigated plant-pathogenic fungi including Colletotrichum spp. In addition to inhibiting mycelial growth , penflufen effectively inhibited F. fujikuroi conidium production. For germination, penflufen could effectively inhibit that of small conidia, but only delay the germination of large conidia. In addition, the sensitivity to penflufen among 100 F. fujikuroi isolates that were collected in areas that were never exposed to SDHIs was determined based on mycelium growth. Sensitivities surprisingly exhibited bimodal distributions, indicating the presence of natural resistance. Cross-resistance was not observed between penflufen in F. fujikuroi and two fungicides that have been extensively applied in field including prochloraz (a DMI) and phenamacril (a 2-cyanoacrylate fungicide), nor with the three SDHIs, fluopyram, benzovindiflupyr, and pydiflumetofen. Additional analysis identified five different point mutations in SDH-A (i.e., at residues 46, 225, 283, 430, and 586) of naturally resistant isolates. These results inform the potential application of the new SDHI fungicide penflufen for managing crop diseases and understanding possible resistance mechanisms among pathogens .
研究领域:
植物病理学
·
真菌学
·
农药科学
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF PHYTOPATHOLOGY
·
2019
·Vol. 167
·期 10
·553-557
·
IF 1.097
Xiaoyu Liang,Yun Peng,Yanchao Liu,Meng Wang,Ye Yang,Yu Zhang
The rubber tree ( Hevea brasiliensis ) is the only resource for commercial natural rubber production and thus has economic importance in Southeast Asia. A spot disease on the leaves of a rubber tree was first discovered in 2017 in Hainan, China. In this study, the fungal isolate MA1 from the infected tissues was determined to be a pathogen of the spot disease by satisfying Koch's postulates. The isolate MA1 was identified as Bipolaris bicolor based on the morphological characteristics and multigene phylogenetic analysis. Among fungicides, prochloraz, iprodione and pyraclostrobin significantly inhibited hyphal growth of B. bicolor under in vitro conditions. This study constitutes the first report on the association of B. bicolor with leaf spot disease of rubber trees worldwide.
研究领域:
植物病理学
·
真菌学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）