ANALYTICA CHIMICA ACTA
·
2025
·
IF 6
Li Chen,Yibo Yan,Changbao Hong,Xiangting Wei,Jianhua Xiong,Chuixiu Huang,Xiantao Shen
Background Simultaneous determination of different natures of analytes is of great significance for saving sample volumes and simplifying analytical procedures. However, sample preparation for the simultaneous extraction of polar and non-polar analytes represents a challenge in sample preparation. Inspired by the successive liquid-phase microextraction (sLPME) method for acidic and basic analytes that we previously developed, we first proposed an efficient successive electromembrane extraction (sEME) system by adjusting the acidity of the donor solution and using binary organic solvents for extraction of polar and non-polar targets from biological samples in this work. Results We performed a detailed optimization of the sEME system. Here, carnitine (C0) and acylcarnitines were selected as model analytes since the demand increased especially in metabolomics studies. The combination of 2-nonanone and 2-nitrophenylpentyl ether (NPPE) was selected as supported liquid membranes (SLMs), and trichloroacetic acid (TCA) 100 % (v/v) was added to donor solution to adjust the acidity of the donor solution after the first sEME process (sEME-1). The recoveries of the targets in blood and urine were 47%–119% and 54%–118%, respectively. Moreover, the sEME systems were evaluated by liquid chromatography tandem mass spectrometry (LC-MS/MS) from biological samples. The limit of detection (LOD) and limit of quantitation (LOQ) of analytes were 0.03–1.33 ng mL −1 and 0.09–4.42 ng mL −1 , respectively. Significance sEME enabled the extraction of polar and non-polar analytes from the same sample under optimal extraction conditions for all target analytes, which provided ideas for efficient sEME of exogenous and endogenous analytes from biological samples for forensic, clinical, and epidemiological studies.
研究领域:
分析化学
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生物医学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2024
·
IF 8.4
Xiaoli Wu,Xingya Huang,Yongzheng Wang,Jingjing Chen,Ye Wan,Jianhua Liu,Wenpeng Li,Jingtao Wang
Two-dimensional (2D) lamellar membranes are favored over other membrane materials. However, the molecule transport behaviors in confined 2D nanochannels remain ambiguous, specifically the role of interlayer spacing which determines the confined effect. Herein, vertically-aligned nanochannel membranes with adjusted interlayer spacing (0.6 nm, 2.1 nm, and 3.9 nm) were fabricated by vermiculite lamellar membranes. These robust and long-range 2D nanochannels maintain stable molecule configuration state throughout the transport process, providing ideal platforms for investigating molecule transport behaviors. We demonstrate that molecules with weak molecule-molecule interactions (mainly nonpolar molecules) continuously collide with each other in the nanochannels. The extremely confined nanochannels (0.6 nm) restrict the random molecule collision and permit the oriented flow along transport direction, thus offering the highest transport efficiency. In contrast, molecules in wider nanochannels (3.9 nm) collide randomly, impairing the velocity of molecules or even compelling some of them to move to the adverse flow direction. This consumes cohesive energy and leads to lower permeance. The transport rate of benzene reaches over 130 L m -2 h -1 bar -1 nm -1 for 0.6 nm-nanochannel membrane, which is 8 times higher than that of 3.9 nm-nanochannel membrane. Compared to nonpolar molecules, the strong molecule-molecule and molecule-channel interactions for polar molecules would weaken this collision effect, thus the difference of transport rate is relatively small with nanochannel size.
研究领域:
材料科学
·
化学工程
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产品关联
DOI
高影响因子
CLAYS AND CLAY MINERALS
·
2020
·Vol. 67
·期 6
·461-470
·
IF 1.507
Zhao Shun-Ping,Guo Yu,Zhu Miao-Miao,Wang Jie,Feng Xiao-Liang,Qiao Qiao,Xu Heng
The construction of organic-inorganic hybrid ferroelectric materials with larger, high-polarity guest molecules intercalated in kaolinite (K) faces difficulties in terms of synthesis and uncertainty of structure-property relationships. The purpose of the present study was to optimize the synthesis method and to determine the mechanism of ferroelectric behavior of kaolinite intercalated with p -aminobenzamide (PABA), with an eye to improving the design of intercalation methods and better utilization of clay-based ferroelectric materials. The K-PABA intercalation compound (chemical formula Al 2 Si 2 O 5 (OH) 4 ∙(PABA) 0.7 ) was synthesized in an autoclave and then characterized using X-ray diffraction (XRD), infrared spectroscopy (IR), thermogravimetric analysis (TGA), and scanning electron microscopy (SEM). The experimental results showed that PABA expanded the kaolinite interlayer from 7.2 Å to 14.5 Å, and the orientation of the PABA molecule was ~70° from the plane of the kaolinite layers. The amino group of the PABA molecule was close to the Si sheet. The presence of intermolecular hydrogen bonds between kaolinite and PABA and among PABA molecules caused macro polarization of K-PABA and dipole inversion under the external electric field, resulting in K-PABA ferroelectricity. Simulation calculations using the Cambridge Sequential Total Energy Package ( CASTEP ) and the ferroelectricity test revealed the optimized intercalation model and possible ferroelectric mechanism.
研究领域:
材料科学
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无机化学
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产品关联
DOI
高影响因子
Frontiers in Materials
·
2021
·
IF 3.515
Cheng Yuchuan,Zhao Zihui,Wang Hui,Hua Letian,Sun Aihua,Wang Jun,Li Zhixiang,Guo Jianjun,Xu Gaojie
Electrorheological (ER) fluids are a type of smart material with adjustable rheological properties. Generally, the high yield stress (>100 kPa) requires high electric field strength (>4 kV/mm). Herein, the TiO2 nanoparticles were synthesized via the sol–gel method. Interestingly, the ER fluid-based TiO2 nanoparticles give superior high yield stress of 144.0 kPa at only 2.5 kV/mm. By exploring the characteristic structure and dielectric property of TiO2 nanoparticles and ER fluid, the surface polar molecules on samples were assumed to play a crucial role for their giant electrorheological effect, while interfacial polarization was assumed to be dominated and induces large yield stress at the low electric field, which gives the advantage in low power consumption, sufficient shear stress, low leaking current, and security.
研究领域:
材料科学
·
物理学
✓ 已验证
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2022
·
IF 10.383
Xia Chen,Jihuai Wu,Guodong Li,Yitian Du,Qi Chen,Chunyan Deng,Yuan Xu,Sijia Zhu,Fangfang Cai,Juanmei Liu,Yuelin Wei,Yunfang Huang
The rapid development of perovskite solar cells (PSCs) makes it one of the most competitive photovoltaic devices in the field of new energy. However, the suboptimal performance and poor stability caused by numerous defects are still the main factors limiting the development of PSCs. Herein, a polarized molecule additive of 4-(aminomethyl) benzonitrile hydrochloride (AMBNCl) is introduced into perovskite. Owing to its special polar electron density distribution, −C≡N group, −NH3+ terminal, and Cl– ions, the modification of AMBNCl can improve the quality of perovskite crystal growth, passivate the defects of Pb2+, adjust the energy level array between the perovskite layer and hole-transport layer, and alleviate the carrier nonradiative recombination. As a result, the AMBNCl-modified device achieves a champion efficiency of 23.52%. The unpacked device still maintained 91.2% of its original efficiency after storing in an air environment (RH ∼40%, 25 °C) for 50 days.
研究领域:
材料科学
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能源科学
·
光伏技术
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES
·
2020
·
IF 0.992
Shiyun Tang,Yuanxing Duan,Feng Chang,Wei Jiang,Fengmei Zhang,Zhihua Liu,Yuting Yang,Chunbo Liu,Yingzhuang Chen
The porous layer open-tube (PLOT) columns, which were characterized by their considerable specific surface area and high permeability, have attracted a growing attention from researchers in liquid chromatography. In this work, a hydrophilic PLOT column rich in carboxylic acid functional groups was successfully synthesized in capillary with an inner diameter of 200 µm by thermally initiated aqueous two-phase polymerization. Methacrylic acid (MAA) areas monomers that responsible for the introduction of polar functional groups, and poly(ethylene glycol) diacrylate (PEGDA) are as cross-linker. The optimized PLOT column has a uniform, moderately thick porous layer, which is tightly bonded to the inner wall without any detachment. The hollow structure gives the PLOT column good permeability, which facilitates fast mass transfer. The systematical evaluations of the resulting PLOT columns were performed by using polar analytes including nucleosides, bases, amides, phenols and carboxylic acids. Those results demonstrated excellent separation performance for the small polar molecules. Compared to the poly(PEGDA) PLOT column, the hydrophilic retention of analytes on poly(PEGDA-co-MAA) porous layer open-tube column is significantly improved by the introduction of carboxylic acids. Furthermore, with modified nucleosides and chlorophenols being disease markers and the persistent pollutant of wide concern, respectively, the separation was optimized and the linear range of the quantitative analysis was examined for both targets. which indicates the potential application of such PLOT column for analysis of real samples.
研究领域:
分析化学
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色谱技术
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产品关联
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
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2024
·
IF 5.8
Xuejiao Wang,Tianzhi Jiang,Renguang Ye,Youjie Hua,Bingpeng Li,Guoqing Liu,Zhiqiang Long,Buqing Zhang,Gongxun Bai,Junjie Zhang,Shiqing Xu
The self-assembly mechanism of porous materials has always been a hot topic and a challenging issue in research. What factors induce the self-assembly process, and how is the temperature sensing performance related to it? Innovatively, in this paper, Gd 2 O 2 S:Er 3+ /Yb 3+ phosphors with different morphologies were synthesized, and elucidated the formation mechanism of flower-like structures through relevant theorems, formulas, and experiments, proposing that polar molecules and dipole-dipole interactions guide the synergistic effect of van der Waals forces and hydrogen bonding, which ultimately induces the self-assembly of spherical structures into flower-like ones. In addition, four representative intermediates were selected to investigate their luminescence and temperature sensing properties. The results show that the flower-like sample can respond more effectively to changes in ambient temperature because of its rich pore structures, and thus exhibit better temperature sensing performance. In-depth research on the self-assembly mechanism of materials helps to predict and regulate their properties, and the unique characteristics of flower-like sample provide new ideas for material selection in the field of high-precision temperature measurement.
研究领域:
材料科学
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光学
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纳米技术
·
温度传感
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产品关联
DOI
高影响因子
INORGANIC CHEMISTRY
·
2020
·
IF 4.825
Xue-Mei Zhao,Dong Li,Hai-Xia Zhao,Yan-Ping Ren,La-Sheng Long,Lan-Sun Zheng
Polar crystal structures have attracted more and more attention, due to their unique characteristics, such as ferroelectricity, piezoelectricity, and nonlinear optical property, etc. However, the construction of polar materials is always accidental, and finding an effective synthesis strategy to construct polar materials remains a challenge. Herein, inorganic–organic hybrid compounds of [C7H14N][FeCl4] (1) ([C7H14N] = quinuclidinium cation) and [C7H14N][GeCl3] (2) were prepared, respectively, to verify the beneficial effect of polar anions on the construction of polar crystals. Compound 1 crystallized in the Pbca space group, while 2 belongs to the P43 space group at room temperature. Investigation into the structure of 2 reveals that the polarity of 2 derives from the triangular pyramid structure of [GeX3]− with lone pair electrons. Meanwhile, 2 undergoes a phase transition from the P43 space group to the center Pm3m at 385 K, leading to the optic–electric switching property. Thus, the present work exhibits the advantage of [GeX3]− as the inorganic constituent component in the hybrid polar materials and provides an effective approach for the construction of a polar molecule-based crystal with a switchable property.
研究领域:
材料科学
·
晶体学
·
电光学
·
无机化学
·
有机化学
✓ 已验证
DOI
PubMed
高影响因子
ELECTROPHORESIS
·
2018
·Vol. 40
·期 4
·521-529
·
IF 2.569
Feng Chang,Yunfang Yue,Zihui Yang,Si Huang,Zhihua Liu,Kunmiao Wang,Yan Peng,Yingzhuang Chen,Ming Ma,Bo Chen
The easy shrinkage and swelling of polymer monolithic column when exposed to mobile phase with different polarity is a problem that cannot be ignored. To overcome this drawback, a convenient aqueous two-phase polymerization approach was used to prepare poly (polyethylene glycol diacrylate, PEGDA) monolithic porous layer open tubular (mono-PLOT) columns (150 μm). The poly(PEGDA) mono-PLOT column with homogeneous polymer porous layer was synthesized successfully. A maximum plate number of 41,500 plates per meter for allyl thiourea was obtained under a velocity of 1.8 mm/s. Several kinds of polar molecule were separated on the proposed mono-PLOT column and a typical hydrophilic interaction retention mechanism was observed. High speed separation of benzoic acids was also carried out, baseline separation of five benzoic acids was successfully achieved within 5 min with a 70 cm mono-PLOT column at 50°C. Furthermore, the resulting PLOT column was also successfully applied to separate standard analytes of three DNA oxidative damage products and RNA-modified nucleosides and four chlorophenols. At last, the column could separate alcohols, alkanes, and aromatic isomers via GC. It had more than 20,000 plates per meter for butanol – higher than commercial coatings open tubular columns.
研究领域:
分析化学
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色谱学
·
高分子科学
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气相色谱
·
亲水作用色谱
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）