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Antibiotics-Basel · 2021 ·Vol. 10 ·期 6 ·681 · IF 4.639

South Africa’s Best BARK Medicines Prescribed at the Johannesburg Muthi Markets for Skin, Gut, and Lung Infections: MIC’s and Brine Shrimp Lethality

Gugulethu P. Khumalo,Nicholas J. Sadgrove,Sandy F. Van Vuuren,Ben-Erik Van Wyk

Indigenous trade of medicinal plants in South Africa is a multi-million-rand industry and is still highly relevant in terms of primary health care. The purpose of this study was to identify today’s most traded medicinal barks, traditionally and contemporaneously used for dermatological, gastrointestinal, and respiratory tract infections; then, to investigate the antimicrobial activity and toxicity of the respective extracts and interpret outcomes in light of pharmacokinetics. Thirty-one popularly traded medicinal barks were purchased from the Faraday and Kwa Mai-Mai markets in Johannesburg, South Africa. Information on the medicinal uses of bark-based medicines in modern commerce was recorded from randomly selected traders. The minimum inhibitory concentration (MIC) method was used for antimicrobial screening, and brine shrimp lethality was used to determine toxicity. New medicinal uses were recorded for 14 bark species. Plants demonstrating some broad-spectrum activities against tested bacteria includeElaeodendron transvaalense,Erythrina lysistemon,Garcinia livingstonei,Pterocelastrus rostratus,Rapanea melanophloeos,Schotia brachypetala,Sclerocarya birrea, andZiziphus mucronata. The lowest MIC value of 0.004 mg/mL was observed againstStaphylococcus epidermidisfor a dichloromethane bark extract ofE. lysistemon. The tested medicinal barks were shown to be non-toxic against theArtemia nauplii(brine shrimp) bioassay, except for a methanol extract fromTrichilia emetica(69.52% mortality). Bacterial inhibition of bark extracts with minimal associated toxicity is consistent with the safety and valuable use of medicinal barks for local muthi market customers. Antimicrobial outcomes against skin and gastrointestinal pathogens are feasible because mere contact-inhibition is required in vivo; however, MIC values against respiratory pathogens require further explaining from a pharmacokinetics or pharmacodynamics perspective, particularly for ingested rather than smoked therapies.Keywords:bark;antibacterial;traditional medicine;Zulu;brine shrimp lethality

研究领域: 药理学 · 微生物学 · 毒理学
✓ 已验证 DOI PubMed 高影响因子
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES · 2024 · IF 7.7

Exploring the versatility of biodegradable biomass aerogels: In-depth evaluation of Firmiana simplex bark microfibers depolymerized by deep eutectic solvent

Amjad Farooq,Haiwei Yang,Zhenhua Ding,Fan Bu,Mingming Guo,Wanlin Sun,Zongqian Wang,Mingwei Tian

In this study, we investigated the use of deep eutectic solvents (DESs) at different molar ratios and temperatures as a green and efficient approach for microfibers (MFs) extraction. Our approach entailed the utilization of Firmiana simplex bark (FSB) fibers, enabling the production of different dimensions of FSB microfibers (FSBMFs) by combining DES pretreatment and mechanical disintegration technique. The proposed practice demonstrates the simplicity and effectiveness of the method. The morphology of the prepared microfibers was studied using the Scanning electron microscopic (SEM) technique. Additionally, the results revealed that the chemical and mechanical treatments did not significantly alter the well-preserved cellulose structure of microfibers, and a crystallinity index of 56.6 % for FSB fibers and 63.8 % for FSBMFs was observed by X-ray diffraction (XRD) analysis. Furthermore, using the freeze-drying technique, FSBMFs in water solutions produced effective aerogels for air purification application. In comparison to commercial mask (CM), FSBMF aerogels' superior hierarchical cellular architectures allowed them to attain excellent filtration efficiencies of 94.48 % (PM 10 ) and 91.51 % (PM 2.5 ) as well as excellent degradation properties were analyzed. The findings show that FSBMFs can be extracted from Firmiana simplex bark, a natural cellulose-rich material, using DES for environmentally friendly aerogel preparation and applications.

CAS / MDL: 67-48-1 7439-91-0
研究领域: 材料科学 · 环境科学
✓ 已验证 产品关联 DOI PubMed 高影响因子
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FITOTERAPIA · 2025 · IF 2.6

Study on chemical composition, anti-inflammatory activity and quality control of the branch bark of Morus alba L.

Wenyuan Li,Lin Chen,Minpeng Li,Kaiye Peng,Xuemei Lin,Yifan Feng,Yun Zou,Xia Wu

In this study, the chemical constituents of branch bark and root bark of Morus alba L. were first qualitatively analyzed by UPLC-Q/TOF-MS. A total of 40 compounds were identified, including 20 flavonoids, 3 stilbenes, 1 phenolic acid, 1 alkaloid, 5 arylbenzofurans and 10 Diels-Alder adducts. Of these, 19 compounds were specific to the root bark, 10 to the branch bark, and 11 were common to both. Total phenolic and flavonoid contents were determined, and anti-inflammatory activities were evaluated. Ethyl acetate extracts of both significantly inhibited NO secretion, with the root bark showing a stronger effect than the branch bark. Chemical components of branch bark were further separated, and the anti-inflammatory activities of these isolated compounds were investigated. Eight compounds were isolated from the ethyl acetate extract of the branch bark of Morus alba L. . These compounds were able to inhibit the release of inflammatory factors, including NO, IL-6, and IL-1β, in a concentration-dependent manner. Among them, compounds SZP-1, SZP-6 and SZP-8 exhibited superior in vitro anti-inflammatory activity, comparable to the positive drug meloxicam at high concentrations. In addition, the quality standard of the branch bark of Morus alba L. was established for the first time according to the 2020 edition of the Chinese Pharmacopoeia. This study provides valuable insights into the medicinal value of the branch bark of Morus alba L. and promotes the comprehensive utilization of mulberry branch resources.

CAS / MDL: 71125-38-7
研究领域: 药理学 · 植物化学 · 分析化学
✓ 已验证 产品关联 DOI PubMed 高影响因子
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INDUSTRIAL CROPS AND PRODUCTS · 2019 · IF 4.191

Effervescent salt and crown ether-assisted matrix solid-phase dispersion extraction of coumarins from Cortex fraxini

Yu-Han Hu,Qiu-Yan Wang,Li-Hong Ye,Juan Yang,Xin Dong,Hui Zheng,Jian Zhou,Jun Cao

A simple, rapid and environmentally friendly method named effervescence-assisted matrix solid-phase dispersion (EA-MSPD) was investigated for the extraction of four coumarins (esculin, esculetin, fraxin and fraxetin) from Crotex fraxini ( C. fraxini ). In this study, an effervescent tablet containing carbon dioxide sources (100 mg sodium bicarbonate and 200 mg sodium dihydrogenphosphate) and an adsorbent (25 mg benzo-15-crown-5) was prepared. The effervescent tablet was dissolved into an aqueous solution, and as a consequence of the effervescence reaction, carbon dioxide was generated, thus making the sample better a dispersion of the extraction solvent (100 mM sodium dodecyl sulfate). The variables that influenced the extraction efficiency included effervescent salts, extraction solvents and crown ether. These values were represented using ultra- high-performance liquid chromatography (UHPLC). Good linearity was exhibited by coefficients of determination all equal to 1, limits of detection ranging from 1.62 to 3.83 ng·mL −1 and limits of quantification ranging from 5.39 to 12.76 ng·mL −1 . The recoveries ranged from 91.37 to 100.29% with relative standard deviations of 0.57–4.58% under optimized conditions. In this work, the proposed EA-MSPD method was successfully applied to extract and identify four coumarins in C. fraxini . Compared with previously reported methods, the method examined herein was faster, greener and more sensitive.

CAS / MDL: 17455-13-9
研究领域: 分析化学 · 药学
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Polymers · 2020 ·Vol. 12 ·期 1 ·107 · IF 3.426

Modification of Rigid Polyurethane Foams with the Addition of Nano-SiO2 or Lignocellulosic Biomass

Qinqin Zhang,Xiaoqi Lin,Weisheng Chen,Heng Zhang,Dezhi Han

Many achievements have been made on the research of composite polyurethane foams to improve their structure and mechanical properties, and the composite foams have been widely utilized in building insulation and furniture. In this work, rigid polyurethane foams (RPUFs) with the addition of different fillers (nano-SiO2, peanut shell, pine bark) were prepared through the one-step method. The effects of inorganic nano-SiO2and organic biomass on foam properties were evaluated by means of physical and chemical characterization. The characterization results indicate that the compressive strength values of prepared foams could fully meet the specification requirement for the building insulation materials. The inorganic and organic fillers have no effect on the hydrogen bonding states in composite RPUFs. Furthermore, compared to the biomass fillers, the addition of nano-SiO2greatly influenced the final residual content of the fabricated foam. All composite foams exhibit closed-cell structure with smaller cell size in comparison with the parent foam. The prepared composite foams have the potential for utilization in building insulation.Keywords:rigid polyurethane foam;peanut shell;pine bark;nano-SiO2;insulation materials

研究领域: 材料科学 · 化学工程
✓ 已验证 产品关联 DOI PubMed 高影响因子
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BIORESOURCE TECHNOLOGY · 2019 · IF 6.669

Zirconium based metal-organic framework in-situ assisted hydrothermal pretreatment and enzymatic hydrolysis of Platanus X acerifolia exfoliating bark for bioethanol production

Ibrahim Nasser Ahmed,Xiu-Li Yang,Amare Aregahegn Dubale,Rong Shao,Rong-Feng Guan,Xiangming Meng,Ming-Hua Xie

Metal-organic framework (MOF) assisted hydrothermal pretreatment and co-catalysis strategy based on UiO-66 MOF is developed for the first time. The Planetree exfoliating bark was pretreated with or without UiO-66 assisted hydrothermal method at a temperature ranging from 160 to 240 °C for 1–3 h residence. With the rise of pretreatment severity, the total reducing sugar (TRS) was increased till reached maximum, 180 mg g −1 , in the presence of UiO-66. The fitting models validate the optimal hydrothermal condition was at 180 °C and 1 h, which was characterized with high TRS and very low yield of furfural and HMF. The TRS from enzymatic hydrolysis reaches maximum, 391 mg g −1 , in the presence of MOF co-catalysis and the maximum ethanol yield achieved was 73%. Altered morphology, higher surface area and porosity are noticed after MOF assisted hydrothermal pretreatment. This study insights the MOFs’ application in lignocellulose biomass processing.

研究领域: 生物能源 · 材料科学 · 植物学
✓ 已验证 产品关联 DOI PubMed 高影响因子
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CHEMICAL ENGINEERING JOURNAL · 2022 · IF 16.744

Biorhythm paralleled release of pheromone by photothermal conversion for Long-term bark beetle control

Qianhao Pan,Jiaxing Fang,Shiming Zhang,Yonglin He,Yapei Wang

The spruce bark beetle Ips typographus , as the most notorious pest in Eurasia spruce forest ecosystem, mainly feed on phloem of spruce tree trunk. The concealment of their habit makes regulation of insect population a difficulty to cope with, contributing to spruce forest recession, destruction of environment balance and forest transformation from carbon sinks into carbon source. Based on the cross point between the biorhythm of the I. typographus and photothermal material, description herein was a novel sunlight-triggered biorhythm-paralleled photothermal sponge (BPPS) for continuous control of I. typographus . Three steps including preparation of sugar template based porous polyurethane (PU) sponge, polypyrrole (PPy) modification and pheromone filling were involved in material manufacturing. The attractant and repellant agents were employed into the PU separately to realize a comprehensive regulation on I. typographus behavior. Laboratory simulation and forest field experiments illustrated that both the rapid release within a short period and long-term effectiveness in 21 days were verified. Due to the advantages of designability, cost-effectiveness and environmental friendliness of our sustained-release sponge, this manufacturing strategy offers great promise for generating photothermal responsive sustained-release material, shedding light on long-term control of injurious trunk borers and environmental protection.

研究领域: 昆虫学 · 环境科学 · 材料科学
✓ 已验证 产品关联 DOI 高影响因子
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CHEMICAL ENGINEERING SCIENCE · 2022 · IF 4.889

Valorization of bark to natural lubrication additives via fractionation based on chemical product engineering concept

Danyang Cao,Jie Zhang,Yuxiang Nie,Shanshan Wang,Xin Feng,Jiahua Zhu,Xiaohua Lu,Liwen Mu

In this work, the natural lubricating components from Cork bark (CB) and Populus bark (PB) were obtained by catalytic reduction fractionation and liquid–liquid extraction. GC–MS, 2D-NMR, and GPC some techniques were used to characterize the chemical composition of the CB and PB extract. The main components of CB and PB are suberin-derived aliphatic and alkaloid, respectively. CB and PB extract have been demonstrated as efficient organic lubricating additives to reduce wear rate and stabilize friction coefficient of paraffin lubricant. Interestingly, the addition of CB or PB extract in paraffin shows better lubrication performance as compared with commercial lubricants. In addition, XPS results show that some compounds such as suberin-derived aliphatic and alkaloid from bark could enhance lubricating oil film to reduce friction and wear. Overall, this work will replace the conventional petroleum based lubricating additives and open a new application venue for bark to improve product value.

CAS / MDL: 142-82-5 67-56-1 67-66-3
研究领域: 化学工程 · 材料科学
✓ 已验证 产品关联 DOI 高影响因子
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SEPARATION AND PURIFICATION TECHNOLOGY · 2025 · IF 9

A scalable surface nanoarchitectonics approach for melaleuca bark-derived biochar: Rapid PFOA removal and superior supercapacitor performance

Manman Xu,Shiqi Fu,Rui Chen,Charlotte S.Q. Christensen,Cankun Chen,Yuqi Fan,Yuhan Cai,Anqi Wang,Jonathan W.C Wong

Based on the principles of sustainable development, the porous carbon material with a hierarchical structure derived from Melaleuca bark was developed and applied in environmental pollution control and energy storage. The Melaleuca bark-derived porous carbon material (MBC x ) is prepared using a scalable surface modification strategy that is a one-step carbonization and activation process. MBC 1 displays a hierarchically micro/mesopore structure with an impressive specific surface area (1956.72 m 2 g −1 ) and a substantial pore volume (1.04 cm 3 g −1 ). It retains the fibrous tubular structure of the precursor while forming interconnected mesoporous structures. As absorbent, the maximum adsorption capacity for perfluorooctanoic acid (PFOA) of MBC 1 is 1702.12 mg/g. MBC 1 shows excellent stability and reusability, with high selectivity and removal rates for PFOA in actual fluorine-containing wastewater. MBC 1 tends to adsorb fluorine atoms compounds with a high degree of fluorination and a greater number of fluorine atoms, suggesting the dominant contribution of hydrophobic interactions. However, polyfluorinated PFAS, in which hydrogen atoms replace fluorine in the perfluorinated structure, generally exhibit reduced adsorption. For energy storage, MBC 1 exhibits efficient charge transfer and ion diffusion properties, making it suitable as an electrode material for supercapacitors. The button-type symmetric supercapacitor based on MBC 1 shows excellent electrochemical performance, with a specific capacitance reaching 230.6F g −1 at a current density of 0.5 A g −1 . This powerful surface engineering strategy offers a promising solution to environmental challenges, while contributing to the advancement of clean energy technologies.

研究领域: 环境科学 · 材料科学 · 能源技术
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Polymers · 2022 ·Vol. 14 ·期 19 ·4127 · IF 4.967

Chemical and Enzymatic Fiber Modification to Enhance the Mechanical Properties of CMC Composite Films

Xiaobao Li,Zhengjie Tang,Zhenbing Sun,John Simonsen,Zhinan Luo,Xiaoping Li,Jeffery J. Morrell

Carboxymethyl cellulose (CMC) is a cellulose derivative that can be obtained from wood, bamboo, rattan, straw, and other cellulosic materials. CMC can be used to produce biofilms for many purposes, but the properties of these resulting films make them unsuitable for some applications. The effects of three kinds of plant fiber addition on CMC film properties was investigated using CMC derived from eucalyptus bark cellulose. Tensile strength (TS) and elongation at break (EB) of CMC/sodium alginate/glycerol composite films were 26.2 MPa and 7.35%, respectively. Tensile strength of CMC composite films substantially increased, reaching an optimum at 0.50 g of fiber. The enhancement due to industrial hemp hurd fiber on CMC composite films was more obvious. Pretreatment with hydrogen peroxide (H2O2) and glacial acetic acid (CH3COOH) produced films with a TS of 35.9 MPa and an EB of 1.61%. TS values with pectinase pretreated fiber films was 41.3 MPa and EB was 1.76%. TS of films pretreated with pectinase and hemicellulase was 45.2 MPa and EB was 4.18%. Chemical and enzymatic treatment both improved fiber crystallinity, but film tensile strength was improved to a greater extent by enzymatic treatment. Surface roughness and pyrolysis residue of the film increased after fiber addition, but Fourier transform infrared spectroscopy (FTIR), opacity, and water vapor transmission coefficients were largely unchanged. Adding fiber improved tensile strength of CMC/sodium alginate/glycerol composite films and broadened the application range of CMC composite films without adversely affecting film performance.Keywords:eucalyptus bark;Yunnan pine wood;bamboo culms;industrial hemp hurd;FTIR;XRD;TG;mechanical properties

研究领域: 材料科学 · 生物化学
✓ 已验证 产品关联 DOI PubMed 高影响因子
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INDUSTRIAL CROPS AND PRODUCTS · 2023 · IF 5.9

Fully biodegradable, hydrophobic, enhanced barrier starch bio-composites with sandwich structure by simulating wood

Chuanwei Zhang,Pengfei Zhang,Yanhui Li,S. Nair Sandeep,Jianyong Li,Maocheng Ji,Sixian Peng,Ning Yan,Fangyi Li

Through a single-sided cavity free-form foaming process, composites with open cell structures similar to wood cells were obtained by using corn starch , pulp fiber , and sisal fibers, which was used as the middle layer of the sandwiched composites. Afterwards, more hydrophobic lignin-containing nanocellulose fibrils from pine bark were coated on the surfaces of the open cell composites by high-pressure gun spraying, simulating the bark of wood to impart barrier property to the final product. The water barrier, mechanical property, apparent density, heat insulation, and biodegradability of the sandwich structured bio-composites were characterized. Experimental results indicated that the water contact angle on the surface of the bio-composite was as high as 92°. The apparent density of the bio-composite was very low, at 0.107 g/cm 3 . The tensile strength of the bio-composites reached 5.3 MPa. After conducting biodegradability tests in soil for 60 days, the bio-composites lost 87 % of its mass.

研究领域: 材料科学 · 生物学
✓ 已验证 DOI 高影响因子
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ACS Applied Materials & Interfaces · 2021 · IF 9.229

Moisture-Wicking and Solar-Heated Coaxial Fibers with a Bark-like Appearance for Fabric Comfort Management

Jinhao Xu,Xuanxuan Du,Binjie Xin,Chiwai Kan,Yaqian Xiao,Zhuoming Chen,Mengjuan Zhou,Qingshuai Yan

Maintaining the human body’s comfort is a predominant requirement of functional textiles, but there are still considerable drawbacks to design an intelligent textile with proper moisture absorption and evaporation properties. Herein, we develop moisture-wicking and solar-heated coaxial fibers with a bark-like appearance for fabric comfort management. The cortex layer of coaxial fibers can absorb moisture via the synergistic effect of the hierarchical roughness and the hydrophilic polymeric matrix. The core layer containing zirconium carbide nanoparticles can assimilate energy from the body and sunlight, which raises the surface temperature of the material and accelerates moisture evaporation. The resulting coaxial fiber-based membrane exhibits an excellent droplet diffusion radius of 2.73 cm, an excellent wicking height of 6.97 cm, and a high surface temperature of 61.7 °C which is radiated by simulated sunlight. Moreover, the designed fabric also exhibits a significant UV protection factor of 2000. Overall, the successful synthesis of such fascinating fibrous membranes enables the rapid removal of sweat from the human body textile, providing a suitable and comfortable microenvironment for the human body.

研究领域: 材料科学 · 纺织工程 · 功能纺织品设计
✓ 已验证 产品关联 DOI PubMed 高影响因子
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