Effects of sertraline hydrochloride with As(III) or Cd on rhizosphere micro-environment and root endophytes in rice
This study investigated the effects of the antidepressant sertraline hydrochloride (Ser-HCI) on rice physiology when combined with arsenic (III) and cadmium. Hydroponic experiments revealed that combined lower concentrations (0.2 and 0.6 mg L -1 ) of Ser-HCl and As (III) or Cd increased rice biomass and reduced pH and low molecular weight organic acids. The fluorescence intensity was enhanced with Ser-HCl and As-only treatments, with a significant difference ( p < 0.05) in the dissolved organic matter index. There was a decrease in endophyte-specific operational taxonomic units, with proteobacteria dominating the rice root endophytes. The addition of Ser-HCl resulted in a 535% increase in the Verrucomicrobiota , which was positively correlated with malic acid and negatively correlated with pH. Functional annotation highlighted alterations in carbohydrate metabolism pathways. This study provides insights into the interactive effects of Ser-HCl on rice when combined with As (III) and Cd, addressing gaps in our understanding of the impact of antidepressants on plant systems.
危险品化学品经营许可证（带存储）