INDUSTRIAL CROPS AND PRODUCTS
·
2018
·
IF 3.849
He Yan,Zi Xiong,Na Xie,Shanzhi Liu,Lianlian Zhang,Fang Xu,Wenhui Guo,Juntao Feng
Clausena lansium ( Lour.) Skeels is an attractive shrub or small tree, a member of the Rutaceae family. The seeds, leaves and roots of this plant have been used as herbal medicines for a long time. In this study, seven amides were isolated from the seeds of Clausena lansium . The antifungal assay indicated that lansiumamide B ( 4 ) and lansiumamide C ( 2 ) displayed the highest antifungal activity against Sclerotinia sclerotiorum with EC 50 values of 4.95 and 13.24 μg/mL, which were both lower than that of carbendazim (EC 50 = 0.64 μg/mL). The structure-activity relationships of these amides were investigated using assays to measure their in vitro antifungal activities against Sclerotinia sclerotiorum . The effect of the most potent compound lansiumamide B on morphology and physiology of S. sclerotiorum were also evaluated. Lansiumamide B caused cell rupture and mycelial abnormalities of S. sclerotiorum , and its curative efficacy (75.17%) against S. sclerotiorum infection was better than that of carbendazim (56.57%). This study demonstrated that amides isolated from C. lansium possessed the potential to be exploited as botanical fungicides for commercial application or can be used as templates for designing new fungicides with novel action modes.
研究领域:
植物化学
·
真菌学
·
药理学
✓ 已验证
DOI
高影响因子
MOLECULES
·
2017
·Vol. 22
·期 5
·735
·
IF 2.861
Ya-Qin Wen,Jinzhen Zhang,Yi Li,Lanzhen Chen,Wen Zhao,Jinhui Zhou,Yue Jin
The phenolic and proline content were determined in honey samples of different floral origins (rapeseed, sunflower, buckwheat andCodonopsis) from five different regions of China. The phenolic and proline profile of these samples were used to construct a statistical model to distinguish honeys from different floral origins. Significant differences were identified among the studied honey samples from multivariate chemometric methods. The proline content varied among the four types of honeys, with the values decreasing in the order: buckwheat >Codonopsis> sunflower > rapeseed. Rapeseed honeys contained a high level of benzoic acid, while rutin,p-coumaric acid,p-hydroxybenzoic acid were present at relatively high levels in buckwheat honeys. Principal component analysis (PCA) revealed that rapeseed honey could be distinguished from the other three unifloral honeys, and benzoic acid, proline and kaempferol could serve as potential floral markers. Using 18 phenolic compounds and proline the honey samples were satisfactorily classified according to floral origin at 94% correct prediction by linear discriminant analysis (LDA). The results indicated that phenolic compounds and proline were useful for the identification of the floral origin of the four type honeys.Keywords:botanical origin;phenolic compounds;proline;chemometrics;unifloral honeys
研究领域:
食品科学
·
化学计量学
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分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
NATURAL PRODUCT RESEARCH
·
2019
·
IF 1.999
Haibo Wu,Tingting Liu,Yuxuan Lian,Wenshu Wang
Two new eremophilenolides, ligushicins A (1) and B (2), and two known compounds including β-sitosterol and ursolic acid were isolated from Ligulariopsis shichuana. The structures of new compounds were established on the basis of 1D and 2D NMR data and HRESIMS data interpretation. The absolute configuration of new compounds was assigned by ECD spectroscopy, and that of ligushicins A (1) was confirmed by X-ray diffraction analysis. The antifungal and antifeedant activities of new compounds were evaluated against four plant pathogenic fungi and third-instar larvae of Plutella xylostella, respectively. Ligushicins A (1) and B (2) exhibited potent antifungal activity against Botrytis cinerea and Fusarium oxysporum with minimum inhibitory concentration (MIC) values ranging from 50 to 100 mg/L, while they also exhibited weak antifeedant activities.
研究领域:
植物化学
·
药理学
·
植物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2022
·
IF 9.221
Hang Yuan,Shaowei Han,Shengming Wang,Peipei Yang,Songwei Li,Hao-Yang Mi,Chuntai Liu,Changyu Shen
Nowadays, hydrogel-based sensors have drawn great attention owing to the growing demand for wearable devices . However, tailoring the property of the hydrogel sensor through a facile approach remains a great challenge. In this work, inspired by natural plants, a stretchable, adhesive and conductive hydrogel was prepared via the coordination between gallic acid (GA) and Zn 2+ and chemical cross-linking. The dynamic crosslinking provided greater structural integrity for the polyvinyl alcohol / polyacrylamide (PVA/PAM) double network, endowing the hydrogel with high mechanical performance (0.25 MPa at 910% tensile strain , and 1.21 MPa at 70% compressive strain). Meanwhile, the presence of GA enabled the hydrogel with excellent repeatable adhesive performance, which greatly solved the problem of signal loss caused by poor adhesion. Moreover, the addition of ZnCl 2 enhanced the ionic conductivity and gauge factor of the hydrogel. Besides, the conductive hydrogel exhibited successively stable changes of resistance signals under different external stimuli (5–500% strains and 80–200 mm/min rates) and superior durability (over 500 cycles). The hydrogel-based wearable sensors demonstrated excellent sensing performance in detecting various human motions. The multifunctional PVA/PAM/GA-Zn 2+ hydrogel has significant applications in soft robots and healthcare monitoring as the flexible strain sensor.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
·
2023
·Vol. 103
·期 15
·7631-7642
·
IF 4.1
Dongshuang Liang,Haosong Wen,Yaxuan Zhou,Taohong Wang,Guangqun Jia,Zongyan Cui,Adan Li
Background Honey aroma is one of its most important properties and it depends on the qualitative and quantitative composition of the volatile compounds. The volatile profile of honey could reveal its botanical origin to avoid a false characterization. Thus, it is of great significance to honey authentication. This study developed and validated a headspace solid-phase microextraction and gas chromatography–mass spectrometry (HS-SPME-GC–MS) method for simultaneous qualitative and quantitative analyses of 34 volatile components in honey. The developed method was applied to 86 honey samples from six different botanical origins, including linden honey, rape honey, jujube honey, vitex honey, lavender honey and acacia honey. Results The volatile fingerprints and quantitative results were simultaneously obtained by using the full scan and selected ion monitoring (SCAN+SIM) MS scanning mode. The limits of quantification (LOQs) and limits of detection (LODs) of 34 volatile compounds were in the ranges of 1–10 ng/g and 0.3–3 ng/g, respectively. And the spiked recoveries ranged between 70.6% and 126.2%, with the relative standard deviations (RSDs) not higher than 45.4%. A total of 98 volatile compounds were found with relative contents determined, and the 34 volatile compounds were determined with absolute concentrations. Based on the volatile fingerprints and the contents of volatile compounds, honey samples from six botanical origins were well classified by principal component analysis and orthogonal partial least-squares discrimination analysis. Conclusions The HS-SPME-GC–MS method was successfully applied to achieve the volatile fingerprints of six types of honey and to quantitatively analyze 34 volatile compounds with satisfying sensitivity and accuracy. Chemometrics analysis showed significant correlations between honey types and volatiles. These results reveal the characteristics of volatile compounds in six types of unifloral honey and provide some supports for honey authentication. © 2023 Society of Chemical Industry.
研究领域:
食品科学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INDUSTRIAL CROPS AND PRODUCTS
·
2015
·
IF 2.837
Li-Hong Tan,Dan Zhang,Gang Wang,Bao Yu,Sheng-Ping Zhao,Jian-Wei Wang,Ling Yao,Wei-Guo Cao
The aim of this study was to compare the flavonoids compositions, content and antioxidant activities of Hawk tea from six botanical origins for screening the most suitable botanical origins. The main flavonoids of Hawk teas from Litsea coreana Levl. var. lanuginose were identified, and six high contents of individual flavonoids (hyperin, isoquercitrin, quercitrin, astragalin, quercetin and kaempferol) were quantitative and comparative analysis. Moreover the potential antioxidant capacity of Hawk tea was measured by using in vitro antioxidant assays. The above experimental data were all used for the principal component analysis. The statistical results showed that the extracts from Machilus chuanchienensis S. Lee and L. coreana Levl. var. lanuginose appeared closely positioned in the positive regions, indicated the higher flavonoids and antioxidant activity compared with other species. Thus, they were temporarily considered as good sources of Hawk tea.
研究领域:
植物化学
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食品科学
·
药用植物学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2024
·
IF 5.7
Ming Yang,Jiatong Zhang,Zhentao Sun,Di Sun
The development of efficient, biobased polyurethane controlled-release fertilizers from sustainable and eco-friendly biomaterials has received increased research attention, owing to concerns regarding global food security and environmental sustainability. Most previous studies focused on replacing petroleum-based polyols with biopolyols; however, the other main raw material, isocyanate, remained a petrochemical product. Herein, all-natural, plant-derived polyurethane-coated urea was successfully developed using castor oil and biobased isocyanate, and the performance of the coating shell before and after modification was compared. The results showed that the incorporation of a low dose of lauric acid copper into the coating material simultaneously enhanced the hydrophobicity and elasticity of the all-biobased polyurethane membrane, which prolonged the nitrogen release longevity from 3 to 112 days. In addition, the modified membrane showed excellent biodegradability in a soil environment. The novel all-biobased polyurethane coating material and modification technique provide insight for developing sustainable and eco-friendly controlled-release fertilizers.
研究领域:
材料科学
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环境科学
·
农业科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2023
·
IF 9.5
Tianhang Shan,Xin Ma,Hui Li,Chuntai Liu,Changyu Shen,Peipei Yang,Songwei Li,Zhenxing Wang,Zhong Liu,Hongguang Sun
It is critical for resource sustainability and environmental security to develop simple and dependable seawater uranium (VI) (U(VI)) enrichment technology. Membrane materials show excellent performance in the field of adsorption due to their pore structure and recyclability. In this study, a functional coating primarily composed of plant-derived tannic acid (TA) and polyethyleneimine was easily decorated on polyvinylidene fluoride (PVDF) microporous membranes for highly efficient uranium extraction via filtration. The synergistic effect of amino group from PEI and polyphenol structure plays an important role to achieve high adsorption capacity and rapid adsorption kinetics toward U(VI). Furthermore, the higher the molecular weight of PEI , the greater the modified membrane's adsorption capacity to U(VI). The membrane adorned with the optimized functional coating demonstrates outstanding removal rates (91%) and adsorption capacity (164.1 mg g −1 at C 0 = 99.55 mg L −1 ) under extremely high permeate flux (11324.54 L m −2 h −1 ) due to its high adsorption capacity and quick adsorption kinetics . Moreover, the functional coating also possesses excellent reusability, antifouling performance, high flux recovery rate (FRR) (∼ 98%) and low flux decay rate (FDR) (<5%) after ten cycles. Particularly, the membrane's U(VI) adsorption capability in natural seawater can increase to 6.86 mg g −1 . Considering the facile and mild modification process, as well as the green and low costing materials, the plant-derived hybrid coatings have a great application prospect in the field of seawater U(VI) extraction.
研究领域:
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
Science Advances
·
2025
·Vol. 11
·期 12
·
IF 12.5
Xueyan Chen,Meirong Song,Lei Tian,Xinxin Shan,Changsi Mao,Minghui Chen,Jiaqi Zhao,Abdul Sami,Haoqiang Yin,Usman Ali,Jiawei Shi,Hehuan Li,Yuqian Zhang,Jinghua Zhang,Shunxi Wang,Chun-Lin Shi,Yanhui Chen,Xiang-Dang Du,Kui Zhu,Liuji Wu
Multidrug-resistant (MDR) bacteria pose a major threat to public health, and additional sources of antibacterial candidates are urgently needed. Noncanonical peptides (NCPs), derived from noncanonical small open reading frames, represent small biological molecules with important roles in biology. However, the antibacterial activity of NCPs remains largely unknown. Here, we discovered a plant-derived noncanonical antibacterial peptide (NCBP1) against both Gram-positive and Gram-negative bacteria. NCBP1 is composed of 11 amino acid residues with cationic surface potential and favorable safety and stability. Mechanistic studies revealed that NCBP1 displayed antibacterial activity by targeting phosphatidylglycerol and cardiolipin in bacterial membrane, resulting in membrane damage and dysfunction. Notably, NCBP1 showed promising efficacy in mice. Furthermore, NCBP1 effectively inhibited the growth of plant fungal pathogens and enhanced disease resistance in maize. Our results demonstrate the unexplored antimicrobial potential of plant-derived NCPs and provide an accessible source for the discovery of antimicrobial substances against MDR bacterial and fungal pathogens.
研究领域:
微生物学
·
植物学
·
药理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
BIOORGANIC CHEMISTRY
·
2025
·
IF 4.7
Huijun Qiang,Junjun Wang,Zhiyuan Ma,Shaowu Pan,Ruili Wang,Meifang Zhu
Regarding the global increase in dental caries, the development of high-quality resin-based materials is essential. However, it is still a challenge to alleviate the polymerization shrinkage of methacrylate monomers. Herein, we constructed the first- and second-generation betulin-based multimethacrylate dendritic monomers (D 1 , D 2 , and D 3 ) via the esterification reaction, which were differed primarily in the number and position of the terminal methacrylate groups. These photo-polymerizable dendritic monomers were introduced as the partial (10 wt%) and total (50 wt%) replacements of bisphenol A glycidyl dimethacrylate (Bis-GMA) in dental restorative resins. Notably, the D 1 4B5T resin, composed of 10 wt% D 1 , exhibited a significantly lower shrinkage (8.02 ± 0.28 %; 17 % reduction) and improved flexural strength and modulus (87.4 ± 0.8 MPa, 1.9 ± 0.1 GPa) than the commercial resin (9.66 ± 0.29 %; 82.1 ± 0.5 MPa; 1.6 ± 0.1 GPa), due to its well-balanced crosslink density and structure properties. Molecular dynamics simulation of these two resins provided mechanistic insights to how the monomer structure affecting the resin shrinkage. The optimal D 1 4B5T resin also possessed better fluidity, cell viability, and acceptable polymerization conversion compared to the commercial control. This study provides new insights into the synthesis of plant-derived polymerizable dendrimers and the creation of high-performance dental resins, endowing them promising for biomedical fields such as teeth restorations.
研究领域:
材料科学
·
口腔医学
·
高分子化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
·
2024
·Vol. 25
·期 14
·7559
·
IF 4.9
Balázs Kürtösi,Adrienn Kazsoki,Romána Zelkó
This systematic review offers a comprehensive analysis of plant-derived extracellular vesicles (PDEVs) as emerging drug delivery systems, focusing on original research articles published between 2016 and 2024 that exclusively examine the use of PDEVs for drug delivery. After a rigorous search across multiple databases, 20 relevant studies out of 805 initial results were selected for analysis. This review systematically summarizes the critical data on PDEV components, isolation methods, and drug-loading techniques. It highlights the potential of PDEVs to significantly enhance drug safety and efficacy, reduce dosage and toxicity, and align drug development with sustainable and environmentally friendly biotechnological processes. This review also emphasizes the advantages of PDEVs over mammalian-derived vesicles, such as cost-effectiveness, higher yield, and reduced immunogenicity. Additionally, it explores the synergistic potential between encapsulated drugs and bioactive compounds naturally present in PDEVs. This study acknowledges the challenges in standardizing isolation and formulation methods for clinical use. Overall, this review provides valuable insights into the current state and future directions of PDEV-based drug delivery systems, highlighting their promising role in advancing pharmaceutical research and development.
研究领域:
药学
·
生物技术
✓ 已验证
DOI
高影响因子
Foods
·
2024
·Vol. 13
·期 12
·1879
·
IF 4.7
Huizhi Jiang,Zhen Li,Shiqing Zhong,Zhijiang Zeng
Triadica cochinchinensishoney (TCH) is collected from the nectar of the medicinal plantT. cochinchinensisand is considered the most important honey variety in southern China. TCH has significant potential medicinal properties and commercial value. However, reliable markers for application in the authentication of TCH have not yet been established. Herein, a comprehensive characterization of the botanical origin and composition of TCH was conducted by determining the palynological characteristics and basic physicochemical parameters. Liquid chromatography tandem-mass spectrometry (LC-MS/MS) was used to investigate the flavonoid profile composition of TCH,T. cochinchinensisnectar (TCN) and 11 other common varieties of Chinese commercial honey. (−)-Gallocatechin gallate (GCG) was identified as a reliable flavonoid marker for TCH, which was uniquely shared with TCN but absent in the other 11 honey types. Furthermore, the authentication method was validated, and an accurate quantification of GCG in TCH and TCN was conducted. Overall, GCG can be applied as a characteristic marker to identify the botanical origin of TCH.
研究领域:
食品科学
·
植物化学
·
分析化学
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）