FLUID PHASE EQUILIBRIA
·
2015
·
IF 2.2
Liying Cai,Tingping Xie,Suying Zhao,Huidong Zheng,Dan Wu
The solubility of d -camphor-10-sulfonic acid (D-CSA, CAS No. 3144-16-9) in seven solvents (ethyl acetate, methyl acetate , n -butyl acetate, isopropyl acetate, glacial acetic acid, acetic anhydride and propionic acid) was measured under atmospheric pressure. The solubility data were correlated by the modified Apelblat equation, the λh equation, the Wilson model and the UNIQUAC model, respectively. And the thermodynamic parameters of D-CSA, molar dissolution enthalpy and entropy, were determined by the Van’t Hoff equation to explain its dissolving behavior in each solvent.
研究领域:
化学工程
·
物理化学
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DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Miao-Miao Jia,Si-Yuan Yang,Ke-Ke Chen,Pan-Pan Zhang,Wei Shao,Zhen Chen,Zi-Meng Xu,Qing-Yun Wu,Yi Li,Ming Xue
Thin-film composite (TFC) reverse osmosis (RO) membranes, fabricated by interfacial polymerization, have achieved significant success in addressing the global water scarcity. Over the past three decades, the camphor sulfonic acid (CSA)/triethylamine (TEA) has been widely used in fabrication of TFC RO membranes. However, the mechanism of this unique formula remains elusive and contentious. In this work, for the first time, deciphering that introducing CSA/TEA into the aqueous phase has negligible impact on the selective polyamide (PA) layer but facilitate the aqueous solution impregnating of porous polysulfone (PSf) support. Specifically, the acidic CSA significantly hinders amine diffusion yet preserves the porosity of the PSf support during high-temperature curing. TEA is essential in modulating the pH changes and balancing the monomer diffusion rate that results from CSA. The COMSOL simulations have further elucidated that the presence of an aqueous solution within the porous support can mitigate the thermal expansion of the PSf, consequently inhibiting the shrinkage of surface pores. The TFC membrane demonstrated a substantial improvement in water permeance due to the preservation of its pore structure. The obtained TFC membrane demonstrated an exceptional NaCl rejection of 99.3 % and a high water flux of 76.8 L m –2 h −1 (2000 ppm NaCl, 15.5 bar), exceeding that of the state-of-the-art TFC RO membranes. Moreover, the RO membrane manifested with long-term stability and good fouling resistance. The mechanistic insights have important implications to more efficient membrane-based desalination and water reuse, thereby reducing energy consumption and minimizing environmental carbon footprint.
研究领域:
材料科学
·
环境工程
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产品关联
DOI
高影响因子
SENSORS
·
2014
·Vol. 14
·期 11
·21453-21465
·
IF 2.048
Zengyuan Pang,Jiapeng Fu,Pengfei Lv,Fenglin Huang,Qufu Wei
Camphor sulfonic acid (CSA)-doped polyamide 6/polyaniline (PA6/PANI) composite nanofibers were fabricated usingin situpolymerization of aniline under different CSA concentrations (0.02, 0.04, 0.06, 0.08 and 0.10 M) with electrospun PA6 nanofibers as templates. The structural, morphological and ammonia sensing properties of the prepared composite nanofibers were studied using scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR), four-point probe techniques, X-ray diffraction (XRD) and a home-made gas sensing test system. All the results indicated that the CSA concentration had a great influence on the sensing properties of CSA-doped PA6/PANI composite nanofibers. The composite nanofibers doped with 0.02 M CSA showed the best ammonia sensing properties, with a significant sensitivity toward ammonia (NH3) at room temperature, superior to that of the composite nanofibers doped with 0.04–0.10 mol/L CSA. It was found that for high concentrations of CSA, the number of PANI–H+reacted with NH3would not make up a high proportion of all PANI–H+within certain limits. As a result, within a certain range even though higher CSA-doped PA6/PANI nanofibers had better conductivity, their ammonia sensing performance would degrade.Keywords:polyaniline;camphor sulfonic acid;polyamide 6;ammonia;gas sensor
研究领域:
材料科学
·
化学工程
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产品关联
DOI
PubMed
高影响因子
DYES AND PIGMENTS
·
2022
·
IF 5.122
Feifei Lu,Peiyu Tan,Dengfeng Ren,Yuge Han
Poly (aniline) (PANI) is considered an ideal material for the modulation of infrared (IR) radiation due to its excellent electrochromic properties. However, the camphorsulfonic acid doping mechanism which results in emittance modulation is not clearly understood. With the goal of enhancing the IR emittance variation (Δε), a PANI film was synthesized by a chemical oxidation and spraying method, and the doping mechanism of CSA concentration effect on Δε was studied by combining Raman spectra, X-ray photoelectron spectra and density functional theory calculations. The results demonstrate that with increasing camphorsulfonic acid concentration, the effect of the doping concentration on the emittance of PANI/Au films can be divided into two stages: (1) the change in the emittance is mainly caused by the shortening of optical penetration depth either under the state of dopant free (non-doped) or a low CSA doping concentration; (2) the change in emittance is mainly caused by the increase in reflectivity of the PANI layer under the increased doping. Due to the joint action of the two factors, the emittance of the PANI film first increases and then decreases with increasing concentration of CSA, and the maximum Δε (0.45) is realized at 1 M. This paper clarifies the mechanism of PANI films with different CSA dopant concentrations and could provide a way to increase the emittance modulation range by adjusting the concentration of the dopants.
研究领域:
材料科学
·
光学
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DOI
高影响因子
PLoS One
·
2021
·Vol. 16
·期 9
·e0255504
·
IF 3.24
Jing Zhang,Zhou-Tao Pei,Ya-Ni Zhao,Meng Zhang,Li-Ling Zhang,Wen-Qiang Wang,Jing-Ya Wu,Ran Yu,Li-Wei Sun
Benzophenone (BPs) and 4-Methylbenzylidene Camphor are used as ultraviolet (UV) filters to protect the skin and hair in personal care products. The discharging of the three chemicals may endanger the receiving water ecosystem. In the present study, the mutagenicity of BP-6, BP-8, and 4-Methylbenzylidene Camphor was tested using the Salmonella typhimurium reverse mutation test (Ames test) in the system with and without rat liver microsomal preparations (S9). Four S . typhimurium strains, TA97, TA98, TA100, and TA102 were employed in the Ames tests. The mutagenicity was detected from all three chemicals. The addition of S9 increased the mutation ratios of three chemicals to four strains, except BP-6 to TA100 strain and 4-MBC to TA97 and TA98 strain. In the mixed experiment, all positive effects were detected in the absence of S9. However, the results all became negative in the presence of S9. For the mixture of BP-6 and 4-MBC, positive results were detected on four tester strains except for the TA100 strain. For the mixture of BP-6, BP-8, and 4-MBC, positive results were detected on four strains. The mixture test results showed antagonism in mutagenicity for the mixture of BP-6 and 4-MBC to TA98 and TA100 strains and the mixture of BP-6, BP-8, and 4-MBC to TA100 and TA102 strains.
研究领域:
环境科学
·
毒理学
·
生物学
✓ 已验证
DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2018
·
IF 6.042
Jiapei Yang,Yin Yu,Datong Wu,Yongxin Tao,Linhong Deng,Yong Kong
Polypyrrole (PPy) was synthesized by a galvanostatic method using (1S)-(+)-10-camphorsulfonic acid ((+)-CSA) as the dopant, and the produced PPy was further overoxidized in a solution of (+)-CSA. A chiral microenvironment was successfully formed in the overoxidized PPy (OPPy) as a result of the synergistic effects of overoxidation and (+)-CSA, resulting in a twisted helical architecture of the OPPy chains. The formation of optically active OPPy was confirmed from aspects of its morphology (SEM and AFM) and circular-dichroism (CD) spectra. Finally, an electrochemical chirality sensor was fabricated on the basis of the resultant OPPy, which exhibited excellent biomolecular homochirality in the discrimination of tryptophan (Trp) enantiomers.
研究领域:
材料科学
·
分析化学
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生物医学工程
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产品关联
DOI
PubMed
高影响因子
MOLECULES
·
2012
·Vol. 17
·期 10
·12049-12060
·
IF 2.386
Zhi Long Liu,Ligang Zhou,Shu Shan Du
The aim of this research was to determine the chemical composition and insecticidal activity of the essential oil ofCurcuma wenyujinY.H. Chen et C. Ling rhizomes against the booklouseLiposcelisbostrychophilaBadonnel and to isolate any insecticidal constituents from the essential oil. The essential oil ofC. wenyujinrhizomes was obtained by hydrodistillation and analyzed by GC-MS. A total of 43 components of the essential oil were identified and the principal compounds in the essential oil were 1,8-cineole (15.26%), camphor (10.12%), germacrone (6.86%), β-elemene (6.33%), curzerene (6.70%), and β-elemenone (5.23%). followed by curzerenone (4.52%), curdione (4.45%) and linalool (4.43%). Based on bioactivity-guided fractionation, the two main active constituents were isolated from the essential oil and identified as 1,8-cineole and camphor. The essential oil ofC. wenyujinrhizomes exhibited contact toxicity againstL. bostrychophilawith an LD50value of 208.85 µg/cm2. Camphor (LD50= 207.26 µg/cm2) exhibited stronger contact toxicity than 1,8-cineole (LD50= 1048.75 µg/cm2) against booklouse. The essential oil ofC. wenyujin(LC50= 2.76 mg/L air) also possessed fumigant toxicity againstL. bostrychophila, while the two constituents, camphor and 1,8-cineole had LC50values of 1.03 mg/L air and 1.13 mg/L air, respectively. The results indicate that the essential oil ofC. wenyujinrhizomes and its constituent compounds have potential for development as natural insecticides or fumigants for control of insects in stored grains.Keywords:Liposcelisbostrychophila;Curcuma wenyujin;contact toxicity;fumigant;essential oil composition;1,8-cineole;camphor
研究领域:
植物学
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昆虫学
·
天然产物化学
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产品关联
DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
·
2017
·
IF 3.387
Li Jiang,Junaid Ali Syed,Yangzhi Gao,Qiuxiang Zhang,Junfeng Zhao,Hongbin Lu,Xiangkang Meng
Conductive polymer coating doped with large molecular organic acid is an alternative method used to protect stainless steel (SS) bipolar plates in proton exchange membrane fuel cells (PEMFCs). However, it is difficult to select the proper doping acid, which improves the corrosion resistance of the coating without affecting its conductivity. In this study, large spatial molecular group camphorsulfonic acid (CSA) doped polypyrrole (PPY) conductive coating was prepared by galvanostatic electropolymerization on 304SS. The electrochemical properties of the coating were evaluated in 0.1 M H 2 SO 4 solution in order to simulate the PEMFC service environment. The results indicate that the coating increased the corrosion potential and shifted E corr towards more positive value, particularly the j corr value of PPY-CSA coated 304SS was dropped from 97.3 to 0.00187 μA cm −2 . The long-term immersion tests (660 h) show that the PPY-CSA coating exhibits better corrosion resistance in comparison with the small acid (SO 4 2− ) doped PPY-SO 4 2− or PPY/PPY-SO 4 2− coatings. Moreover, the PPY-CSA coating presents low contact resistance and maintains strong corrosion resistance during the prolonged exposure time due to barrier effect and anodic protection.
研究领域:
材料科学
·
电化学
·
能源工程
✓ 已验证
DOI
高影响因子
Foods
·
2023
·Vol. 12
·期 2
·293
·
IF 5.2
Pengbo Wang,Dongman Wan,Ting Peng,Yujing Yang,Xuefang Wen,Xianghui Yan,Jiaheng Xia,Qingwen Zhu,Ping Yu,Deming Gong,Zheling Zeng
Cinnamomum camphoraseed kernel oil (CCSKO) is one of the important natural medium chain triglycerides (MCT) resources, with more than 95.00% of medium chain fatty acids found in the world, and has various physiological effects. However, CCSKO has not been generally recognized as a safe oil or new food resource yet. The acute oral toxicity test and a standard battery of genotoxicity tests (mammalian erythrocyte micronucleus test, Ames test, and in vitro mammalian cell TK gene mutation test) of CCSKO as a new edible plant oil were used in the study. The results of the acute oral toxicity test showed that CCSKO was preliminary non-toxic, with an LD50value higher than 21.5 g/kg body weight. In the mammalian erythrocyte micronucleus test, there was no concentration-response relationship between the dose of CCSKO and micronucleus value in polychromatic erythrocytes compared to the negative control group. No genotoxicity was observed in the Ames test in the presence or absence of S9 at 5000 μg/mL. In vitro mammalian cell TK gene mutation test showed that CCSKO did not induce in vitro mammalian cell TK gene mutation in the presence or absence of S9 at 5000 μg/mL. These results indicated that CCSKO is a non-toxic natural medium-chain oil.Keywords:Cinnamomum camphoraseed kernel oil;acute oral toxicity;genotoxicity assessment;medium chain oil;safety assessment
研究领域:
毒理学
·
食品科学
·
药理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
International Journal of Nanomedicine
·
2023
·
IF 8
Yixuan Wang,Sisi Cao,Kaiyue Yu,Fengdie Yang,Xiuming Yu,Yuanhao Zhai,Chuanbin Wu,Yuehong Xu
Background: Topical application of tacrolimus (FK506) was effective in treating atopic dermatitis (AD); however, the therapeutic efficiency is hampered by its poor penetration into the skin and local side effects of transient irritation symptoms with a burning sensation, a feeling of warmth or heat. Menthol and camphor have been widely used in topical compound formulations for adjunctive pharmacotherapy for antipruritics and analgesics owing to their cool nature, and both present skin penetration enhancing effects. Moreover, they can form a liquid eutectic oil to solubilize hydrophobic drugs.Purpose: Taking advantages of menthol/camphor eutectic (MCE), this work aims to integrate FK506 into MCE to construct a microemulsion system, i.e., FK506 MCE ME, which simultaneously enhances the percutaneous delivery and treatment efficacy, while reduces the side effects of FK506.Methods: The formulation of FK506 MCE ME was optimized and characterized. Different formulations containing FK506 were topically administered to treat 1–chloro–2, 4–dinitrobenzene (DNCB)-induced murine AD.Results: MCE solubilized FK506. FK506 in MCE ME penetrated skin in vitro more than in the commercial ointment, and MCE predominantly exerted the enhancing effects in MCE ME. FK506 MCE ME or FK506 MCE ME gel had greater effects on clinical symptoms, histological analysis, and IgE than did commercial FK506. The anti-pruritic and down-regulation of substance P effects of MCE ME vehicle mitigated the side effects of FK506 application.Conclusion: MCE ME presented the excellent properties of simultaneously enhancing the percutaneous delivery and treatment efficacy, while reducing the side effects of FK506 for AD. Therefore, MCE ME is a promising nanoscale system for FK506 to effectively treating AD with low irritation and high medication adherence.Chemical compounds studied in this article: Tacrolimus (PubChem CID: 445643); menthol (PubChem CID: 1254); camphor (PubChem CID: 2537)
研究领域:
药剂学
·
皮肤科
·
纳米技术
·
药物递送系统
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2024
·
IF 5.7
Li Zhang,Yizhong Huang,Xinying Duan,Hongyan Si,Hai Luo,Shangxing Chen,Liheng Liu,Haohua He,Zongde Wang,Shengliang Liao
Rice sheath blight, caused by the fungus Rhizoctonia solani, poses a significant threat to rice cultivation globally. This study aimed to investigate the potential mechanisms of action of camphor derivatives against R. solani. Compound 4o exhibited superior fungicidal activities in vitro (EC50 = 6.16 mg/L), and in vivo curative effects (77.5%) at 500 mg/L were significantly (P < 0.01) higher than the positive control validamycin·bacillus (66.1%). Additionally, compound 4o exhibited low cytotoxicity and acute oral toxicity for adult worker honeybees of Apis mellifera L. Mechanistically, compound 4o disrupted mycelial morphology and microstructure, increased cell membrane permeability, and inhibited both PDH and SDH enzyme activities. Molecular docking and molecular dynamics analyses indicated a tight interaction of compound 4o with PDH and SDH active sites. In summary, compound 4o exhibited substantial antifungal efficacy against R. solani, serving as a promising lead compound for further optimization of antifungal agents.
研究领域:
植物病理学
·
植物化学
·
分子生物学
✓ 已验证
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2017
·
IF 7.504
Serge Ostrovidov,Majid Ebrahimi,Hojae Bae,Hung Kim Nguyen,Sahar Salehi,Sang Bok Kim,Akichika Kumatani,Tomokazu Matsue,Xuetao Shi,Ken Nakajima,Shizu Hidema,Makoto Osanai,Ali Khademhosseini
In this study, composite gelatin–polyaniline (PANI) nanofibers doped with camphorsulfonic acid (CSA) were fabricated by electrospinning and used as substrates to culture C2C12 myoblast cells. We observed enhanced myotube formation on composite gelatin–PANI nanofibers compared to gelatin nanofibers, concomitantly with enhanced myotube maturation. Thus, in myotubes, intracellular organization, colocalization of the dihydropyridine receptor (DHPR) and ryanodine receptor (RyR), expression of genes correlated to the excitation–contraction (E–C) coupling apparatus, calcium transients, and myotube contractibility were increased. Such composite material scaffolds combining topographical and electrically conductive cues may be useful to direct skeletal muscle cell organization and to improve cellular maturation, functionality, and tissue formation.
研究领域:
生物材料
·
组织工程
·
肌肉生理学
·
生物医学工程
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）