JOURNAL OF HAZARDOUS MATERIALS
·
2018
·
IF 6.434
Yue Meng,Xiaofeng Zhang,Guoxiang Pan,Shengjie Xia,Zheming Ni
A novel hybrid layered material–Schiff Base-Zinc Complexes intercalated ZnCr-LDHs-supported ZnO–was synthesized by one-step coprecipitation method and characterized by XRD, UV–vis DRS, SEM, TEM, BET, ICP-AES and XPS analysis. The influences of the three Zn components (intercalated between the layers, supported on the surface, distributed in the host layers of the layered material) on the crystallinity and the photocatalytic activity of ZnO/ZnCr-SalenZn-LDHs for Rhodamine B (RhB) degradation were studied in detail by orthogonal design. The results showed that the percentage of the three components has a great effect on the structure and photocatalytic performance of ZnO/ZnCr-SalenZn-LDHs. The SalenZn intercalated between the layers and the Zn distributed in the layers of the layered material were the main influencing factors, and the ZnO supported on the surface of the layered material was the secondary influencing factor. The optimum initial molar ratios were SalenZn:Cr = 0.5, Zn:Cr = 3, and ZnO:Cr = 0.75, respectively, and the photocatalytic degradation efficiency of RhB reached 96.9%. In addition, a possible mechanism of photocatalysis was discussed from the perspectives of photogenerated reactive species and photoinduced carries transfer. While, the regeneration of the best photocatalytic material was also investigated in detail.
研究领域:
材料科学
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环境科学
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产品关联
DOI
PubMed
高影响因子
Polymers
·
2021
·Vol. 13
·期 12
·1986
·
IF 4.329
Xuhan Ding,Guang Xu,Dengfei Wang,Zhenmin Luo,Tao Wang
The application of polymer colloids is a promising approach for bauxite residue dust pollution control. However, due to the existence of synergistic aging, the efficiency of colloid dynamic viscosity to predict the dust control performance of bauxite residue is unclear. Previous studies were also rarely performed under synergistic aging conditions. Thus, this paper investigates the relationship between colloids’ viscosity and dust control performance under synergistic aging modes. Results illustrated that the binary colloid achieved better dust control performance than unitary colloid for their higher viscosity and penetration resistance. For both unitary and binary colloid, higher viscosity results in better crust strength. A logarithmic relationship was found for viscosity and dust erosion resistance under unitary aging. However, Only the dynamic viscosity of colloids in solid-liquid two-phase conditions, rather than dissolved in deionized water, can effectively predict the dust control performance under synergistic aging conditions.Keywords:predictor;dust control performance;synergistic aging;orthogonal design;dynamic viscosity;penetration resistance
研究领域:
环境科学
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材料科学
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产品关联
DOI
PubMed
高影响因子
INTEGRATED FERROELECTRICS
·
2017
·
IF 0.457
Wei Hong,Jielin Wang,Qingshan Li,Heng Zhang,Guangzhong Xing
In this paper, the researcher first designed molecular structure of water-soluble polyurethane phase change material. Then, by taking HDI, PEG, chain extender (DMPA, BDO, EDA), catalyst (DBTDL) and neutralizing agent (TEA) as the main raw material, the author prepared waterborne polyurethane phase change material (WPUPC), which is available for wet spinning. The orthogonal design determined the optimal ratio of raw materials, namely, DMPA content is 7 wt%, R equals 6, emulsifying temperature is 30°C, the reaction temperature is 60°C and the reaction time is 180 min. What's more, WPUPCM was characterized utilizing FTIR, DSC-TG and TG-FTIR. A series of tests indicated that this experiment successfully prepared WPUPCM, which has the following advantages: reversible phase change process, high thermal stability, excellent thermal cycling stability, safety and environmental protection. It is foreseeable that this material has broad application prospects in the field of functional textiles.
研究领域:
材料科学
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纺织工程
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化学工程
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产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2015
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IF 3.391
Cunshan Zhou,Jiali Hu,Haile Ma,Abu ElGasim A. Yagoub,Xiaojie Yu,John Owusu,Haiyan Ma,Xiaopei Qin
Protamex catalyzed corn gluten meal (CGM) hydrolysis peptides (CHP) were prepared. Orthogonal design L 16 (4 5 ) was used to optimize processing variables of CGM concentration, CGM heat pretreatment (121 °C) time, and enzymolysis pH, temperature, and time. Degree of hydrolysis (DH), undigested residue ratio, molecular weight (MW) distribution and DPPH radical inhibition were selected as analysis indicators. Optimum variables were CGM concentration of 18%, heat pretreatment time of 40 min, and enzymolysis pH, temperature and time of 7.5, 55 °C and 24 h, respectively. Verification test showed that CHP IC 50 for scavenging hydroxyl radical was the best and then followed by reducing power. Oligopeptides improved after hydrolysis at the expense of di- and tripeptides, suggesting formation of soluble aggregates from low MW peptides. The increase in the DH, oligopeptides, Alanyl-Tyrosine, and antioxidant free amino acids coincided with the improvement in the antioxidant activity of CHP.
研究领域:
食品科学
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生物化学
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DOI
PubMed
高影响因子
JOURNAL OF SEPARATION SCIENCE
·
2020
·Vol. 43
·期 7
·1356-1364
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IF 2.878
Liangqun Chen,Hongbing Liang,Jun Xing
In this work, N,N,N -tri(2-carboxyethyl)-3-(2-aminoethylamino)propyl-trimethoxysilane was prepared as a multidentate functional monomer. The 3D model of the monomer coordinating with Cu 2+ indicated that the monomer is able to provide five ligating atoms like ethylenediaminetetraacetic acid-Cu 2+ to complex with Cu 2+ . When Cu 2+ was used as a template ion, the synthesis conditions of Cu 2+ -imprinted polymers were optimized upon orthogonal design. It is interesting to find that Cu 2+ -imprinted polymer offers a selectivity coefficient of 192.2 when the molar ratio of Cu 2+ to monomer was exactly 1:1. That means there is no excess ligating atom in the ion-imprinted polymer and therefore, the nonspecific adsorption could be avoided. Benefiting from the excellent selectivity of Cu 2+ -imprinted polymer, even if the concentration of Zn 2+ was 25 times that of Cu 2+ , Cu 2+ -imprinted polymer still affords a high selectivity coefficient. Finally, the optimal synthesis conditions for Cu 2+ -imprinted polymer, except the pH, were adopted to prepare Ni 2+ -imprinted polymer, and Ni 2+ -imprinted polymer also offered satisfying selectivity to Ni 2+ . That implies this multidentate monomer is adaptable in ion imprinting and, the optimal synthesis conditions of Cu 2+ -imprinted polymer except pH are likely suitable for the imprinting of other ions besides Cu 2+ .
研究领域:
化学
·
材料科学
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DOI
PubMed
高影响因子
ENERGY & FUELS
·
2023
·
IF 5.3
Mao Chen,Leiting Shi,Zhongbin Ye,Shanshan Zhu,Xiao Wang,Xuwei Liang,Zheng Shu,Hong Chen
This paper discussed the selection of functional monomers and optimal synthesis conditions for hyperbranched copolymer named as HVR, a novel polymer flooding chemical, intended to enhance offshore heavy oil recovery. The potential application of HVR as a polymer for oil displacement was also evaluated. Through experiments and molecular simulations, functional monomers AOS and OP-10 for Bohai heavy oil were screened out due to their high viscosity reduction rates for oil, both above 90%. Moreover, the interaction energy calculation results suggested that AOS and OP-10 were more likely to spontaneously disperse asphaltene aggregation. Furthermore, the influence of various factors on the synthesis of HVR was discussed using orthogonal design, and optimal synthesis conditions were determined. The optimal conditions for HVR synthesis are as follows: polymerization concentration of 30 wt %, initiator dosage of 1 wt %, initiation temperature of 50 °C, and system pH of 7; the sum of OP-10 and AOS accounts for 29.9 wt %, with a molar ratio of 1:1; the total amount of AM and AA accounts for 79.9 wt %, with a mole ratio of 6.5:3.5; and 3.0 G PAMAM accounts for 0.2 wt %. Moreover, HVR demonstrated good mobility control capacity and improved the recovery of heavy oil significantly in core flooding tests. Injecting a slug of 0.3 PV of HVR led to the additional recovery of 21.96 and 16.04% for oil viscosities of 350 and 500 cP, respectively. Notably, HVR’s additional recovery was over 7% higher than that of conventional hydrophobically associating polymer. These findings highlight the potential of HVR as a novel polymer to enhance the heavy oil recovery.
研究领域:
石油工程
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化学工程
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材料科学
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产品关联
DOI
高影响因子
Materials
·
2025
·Vol. 18
·期 24
·5550
·
IF 3.2
Xianpeng Huang,Na Wei,Fengshuang Wang,Xiaoli Zhang
Cordierite diesel particulate filters (DPFs) were prepared using pure cordierite powder with organic binders, sodium silicate aids and pore formers by extrusion technique. The orthogonal test method was adopted to investigate the optimal value of the multi-objective and multi-factor problems. Based on results from statistical analysis, sintering temperature is the most important factor. The optimal parameters for balanced overall performance were determined as a 3 h holding time, 10 wt.% pore former, 12 wt.% sintering aid, and a sintering temperature of 1150 °C, representing a compromise among the individually optimal conditions for porosity, compressive strength, and thermal shock resistance identified by range analysis. The sodium silicate liquid increased and viscosity decreased with the increasing of temperature, which led to the formation of glass phases and the improvement of density. Therefore, with increasing sintering temperature, the porosity and coefficient of thermal expansion decreased. Both the mechanical properties and chemical stability of the prepared samples are strengthened. When the sintering temperature was 1150 °C, the prepared samples with high porosity (56.04%), compressive strength (5.88 MPa), bending strength (13.10 MPa), and low thermal expansion coefficient (CTE, 1.82 × 10 −6 /°C) showed the best comprehensive performance of thermal shock resistance and filtration efficiency. These results demonstrate great potential for DPF applications and provide a reference for the design of other honeycomb ceramics with optimum level of liquid phase.
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DOI
PubMed
高影响因子
BIOCATALYSIS AND BIOTRANSFORMATION
·
2022
·
IF 2.325
Mingxin Zhu,Shuyi Guo,Rongchen Mang,Hua Zhou
Sebacic esters have excellent lubricity, thermal stability, and biodegradability and therefore are widely used as aerospace lubricants, metal working oil, or engine oil. They are mainly produced by chemical synthesis which, however, may cause environmental pollution, its enzymatic synthesis represents a more environmentally friendly alternative. A few reports have described the synthesis of sebacic esters employing immobilised lipases, but these biocatalytic reactions were exclusively carried out in solvent-free systems and thus, could have been limited by slow reaction rates and high reaction temperatures due to poor enzyme dispersion, low substrate solubility, and high viscosity of the reaction mixture. The current study investigated the biosynthesis of dioctyl sebacate in toluene by Novozym 435, a commercial immobilised lipase. The reaction parameters were investigated using the single factor approach and an orthogonal array design. The optimal conditions obtained were as follows: 10 mL toluene, sebacic acid,1 mmol (202.25 mg); molar ratio of sebacic acid to 1-octanol, 1:3; Novozym 435, 0.03 g; 4 Å molecular sieves, 1.5 g; reaction temperature, 40 °C; reaction time, 30 h. A dioctyl sebacate conversion rate of 93% was achieved under these optimal conditions. In particular, the addition of molecular sieves to the reaction mixture markedly improved the product yield. The reaction temperature was low enough to make the operation easy and energy-efficient and therefore, well suited for large-scale production.
研究领域:
化学工程
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生物化学
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环境科学
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产品关联
DOI
高影响因子
Materials Chemistry Frontiers
·
2022
·Vol. 6
·期 9
·1137-1149
·
IF 8.683
Sheng Jie Yuan,Zhong Quan Peng,Min Zhi Rong,Ming Qiu Zhang
To enhance the intrinsic thermal conduction of liquid crystalline epoxy (LCE), a novel strategy based on interlocked polymer networks is proposed. Two cured versions of LCE respectively containing Schiff base bonds and Diels–Alder (DA) bonds are synthesized, and then well mixed in a co-solvent enabling topological reorganization of the single LCE networks via the reversible reactions of the built-in dynamic covalent bonds. The thermal conductivity of the interlocked LCE networks prepared according to the optimal formulation offered by orthogonal design is significantly increased in comparison with the parent single-LCE networks. Besides, although the thermal conductivity of the raw LCE employed in the current work is not that high and the mesogen monomer has the simplest structure, the interlocked networks are able to bring the liquid crystals into full play without changing the chemical structure of the mesogens, as characterized by the very high thermal conductivity per unit weight of liquid crystal. Further investigation of the underlying mechanism suggests that the synergy among the mesogens, the interlocked structure and the inter-component hydrogen bonds accounts for the promotion of heat transmission. Considering the easy access of the relevant chemicals and the simplicity of the materials preparation, the technology developed in the present work may have remarkable potential for future applications.
研究领域:
材料科学
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高分子化学
·
热工程
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DOI
高影响因子
Pharmaceutics
·
2021
·Vol. 13
·期 3
·303
·
IF 6.321
Jia Wen,Xiuge Gao,Qian Zhang,Benazir Sahito,Hongbin Si,Gonghe Li,Qi Ding,Wenda Wu,Eugenie Nepovimova,Shanxiang Jiang,Liping Wang,Kamil Kuca,Dawei Guo
Tilmicosin (TMS) is widely used to treat bacterial infections in veterinary medicine, but the clinical effect is limited by its poor solubility, bitterness, gastric instability, and intestinal efflux transport. Nanostructured lipid carriers (NLCs) are nowadays considered to be a promising vector of therapeutic drugs for oral administration. In this study, an orthogonal experimental design was applied for optimizing TMS-loaded NLCs (TMS-NLCs). The ratios of emulsifier to mixed lipids, stearic acid to oleic acid, drugs to mixed lipids, and cold water to hot emulsion were selected as the independent variables, while the hydrodynamic diameter (HD), drug loading (DL), and entrapment efficiency (EE) were the chosen responses. The optimized TMS-NLCs had a small HD, high DL, and EE of 276.85 ± 2.62 nm, 9.14 ± 0.04%, and 92.92 ± 0.42%, respectively. In addition, a low polydispersity index (0.231 ± 0.001) and high negative zeta potential (−31.10 ± 0.00 mV) indicated the excellent stability, which was further demonstrated by uniformly dispersed spherical nanoparticles under transmission electron microscopy. TMS-NLCs exhibited a slow and sustained release behavior in both simulated gastric juice and intestinal fluid. Furthermore, MDCK-chAbcg2/Abcb1 cell monolayers were successfully established to evaluate their absorption efficiency and potential mechanism. The results of biodirectional transport showed that TMS-NLCs could enhance the cellular uptake and inhibit the efflux function of drug transporters against TMS in MDCK-chAbcg2/Abcb1 cells. Moreover, the data revealed that TMS-NLCs could enter the cells mainly via the caveolae/lipid raft-mediated endocytosis and partially via macropinocytosis. Furthermore, TMS-NLCs showed the same antibacterial activity as free TMS. Taken together, the optimized NLCs were the promising oral delivery carrier for overcoming oral administration obstacle of TMS.Keywords:tilmicosin;nanostructured lipid carriers;orthogonal design;intestinal absorption;MDCK-chAbcg2/Abcb1 cell monolayer
研究领域:
药学
·
兽医学
·
纳米技术
·
药物递送系统
·
药代动力学
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产品关联
DOI
PubMed
高影响因子
AAPS PHARMSCITECH
·
2017
·Vol. 19
·期 2
·541-550
·
IF 2.451
Liu Daichun,Galvanin Federico,Yu Ying
The purpose of this study was to prepare ginkgolide B (GB) lyophilized powder for injection with excellent appearance and stable quality through a formulation screening and by optimizing the freeze-drying process. Cremophor EL as a solubilizer, PEG 400 as a latent solvent, and mannitol as an excipient were mixed to increase the solubility of GB in water to more than 18 times (about from 2.5 × 10 −4 mol/L (0.106 mg/mL) to 1.914 mg/mL). Formulation screening was conducted by orthogonal design where the content of GB in the solution before lyophilization (using external standard method of HPLC) and reconstitution time after lyophilization were the two evaluation indexes. The optimized formulations were GB in an amount of 2 mg/mL, Cremophor EL in an amount of 16% ( v / v ), PEG 400 in an amount of 9% ( v / v ), mannitol in an amount of 8% ( w / v ), and the solution pH of 6.5. Through four single-factor experiments (GB adding order, preparation temperature of GB solution, adding amount, and adsorption time of activated carbon), the preparation process of GB solution was confirmed. The glass transition temperature of maximally GB freeze-concentrated solution was − 17.6°C through the electric resistance method. GB lyophilized powder began to collapse at − 14.0°C, and the fully collapsed temperature was − 13.0°C, which were determined by freeze-drying microscope. When the collapse temperature was determined, the primary drying temperature was obtained. Thereby, the freeze-drying curve of GB lyophilized powder was initially identified. The freeze-drying process was optimized by orthogonal design, the qualified product appearance and residual moisture content were the two evaluation indexes. The optimized process parameters and process were (1) shelf temperature, decreased from room temperature to − 45.0°C, at 0.5°C/min in 2 h; (2) shelf temperature increased from − 45.0 to − 25.0°C, at 0.1°C/min, maintained for 3 h, and the chamber pressure was held at 10 Pa; (3) shelf temperature was increased from − 25.0 to − 15.0°C at 0.1 °C/min, maintained for 4 h, and the chamber pressure was held at 10 Pa; and (4) shelf temperature was increased from − 15.0 to 20.0°C at 1.0 °C/min, maintained for 4 h, and the chamber pressure was raised up to 80 Pa. In these lyophilization process conditions, the products complied with relevant provisions of the lyophilized powders for injection. Meanwhile, the reproducibility was satisfactory. Post-freezing annealing had no significantly beneficial effects on shortening the freeze-drying cycle and improving the quality of GB lyophilized powder.
研究领域:
药学
·
药剂学
·
药物传递系统
·
制药技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）