JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
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2020
·
IF 3.306
Haochi Liu,Jie Ding,Ligang Chen,Lan Ding
A novel approach was proposed to prepare carbon dots (CDs) by acid carbonization and hydrothermal treatment of pork rib bones from food waste. The synthesized animal waste biomass CDs have the merits of eco-friendly, superior fluorescence properties and biocompatibility. The fluorescence of animal waste biomass CDs could be quenched efficiently by dithizone due to the coordination effect. With the addition of dimethoate, the dithizone ligands at CDs are replaced by hydrolysates, and hence the fluorescence is recovered. Thus, a sensing platform was constructed based on the coordination-originated fluorescence of animal waste biomass CDs which can sensitively and selectively detect dimethoate due to a simple displacement mechanism. Upon optimal conditions, the detection limit of dimethoate is 0.064 μM. The linear ranges were obtained in a range of 0.15 μM–5.0 μM. The method is rapid, convenient and environmentally acceptable that can directly detect dimethoate in water samples with recoveries of 93 %–105 %, and the relative standard deviations (RSDs) were 2 %–6 %, respectively. This simple strategy can be used to develop the fluorescence recovery sensors for chemical detection.
研究领域:
分析化学
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环境科学
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食品科学
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产品关联
DOI
高影响因子
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
·
2023
·
IF 4.7
Yuanzhao Wu,Tianyi Chen,Yumei Xia,Jiawen Wang,Anli Wang,Binjie Wang,Jiye Wang,Weixuan Yao
Methidathion is a highly effective organophosphorus pesticide and is extensively utilized for the control of insects in agricultural production. However, there is little information on the adverse effects and underlying mechanisms of methidathion on aquatic organisms . In this work, embryonic zebrafish were exposed to methidathion at concentrations of 4, 10, and 25 mg/L for 96 h, and morphological changes and activities of antioxidant indicators alterations were detected. In addition, the locomotor behavioral abilities of zebrafish exposed to methidathion were also measured. To further explore the mechanism of the toxic effects of methidathion, gene expression levels associated with cardiac development, cell apoptosis, and the immune system were tested through qPCR assays. The findings revealed that methidathion exposure could induce a decrease in survival rate, hatchability, length of body, and increase in abnormality of zebrafish, as well as cardiac developmental toxicity . The LC 50 value of methidathion in zebrafish embryos was determined to be about 30.72 mg/L at 96 hpf. Additionally, methidathion exposure triggered oxidative stress in zebrafish by increasing SOD activity, ROS, and MDA content. Acridine orange (AO) staining indicated that methidathion exposure led to apoptosis, which was mainly distributed in the pericardial region. Furthermore, significant impairments of locomotor activity in zebrafish larvae were induced by methidathion exposure. Lastly, the expression of pro-inflammatory factors including IFN-γ, IL-6, IL-8, CXCL-clc, TLR4 , and MYD88 significantly up-regulated in exposed zebrafish. Taken together, the results in this work illustrated that methidathion caused developmental toxicity, cardiotoxicity, and immunotoxicity in embryogenetic zebrafish.
研究领域:
环境科学
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毒理学
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水生生物学
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DOI
PubMed
高影响因子
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
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2025
·
IF 4.6
Jia Wei,Yi Zhang,Wangui Peng,Weihong Huang,Yunfei Cao,Wenming Yang,Wanzhen Xu
Pesticide residues in food pose significant risks to human health, necessitating accurate monitoring methods. To address this, a lattice distortion strategy-based highly sensitive photoelectrochemical (PEC) sensor was developed for profenofos (PFF) detection. Substitution of Bi 3 + with Co 2+ in the Bi 2 MoO 6 lattice induced enhanced lattice distortions and oxygen vacancies, reducing the bandgap and dramatically improving visible-light absorption and charge transfer efficiency. These modifications synergistically boosted PEC performance, with 4 % Co-doped Bi 2 MoO 6 achieving optimal results, including a reduced narrowed bandgap (2.28 eV) and a significantly enhanced photocurrent density compared to pristine Bi 2 MoO 6 . The sensor exhibited a broad linear detection range (0.5 mg L −1 to 0.01 ng L −1 ) and an ultralow detection limit of 3.3 pg L −1 , demonstrating excellent sensitivity and selectivity in real food samples. This work presents an innovative efficient, non-toxic, and eco-friendly tool for pesticide residue detection, paving new avenues for food safety monitoring and public health protection.
研究领域:
食品科学
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环境科学
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分析化学
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产品关联
DOI
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
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2019
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IF 3.571
Pingyue Wang,Huanhuan Li,Md Mehedi Hassan,Zhiming Guo,Zheng-Zhu Zhang,Quansheng Chen
In this study, a highly sensitive upconversion fluorescence (FL) biosensor was developed for the detection of organophosphorus pesticides (OPs) based on an acetylcholinesterase (AChE) modulated FL “off–on–off” strategy. The luminescence of synthesized UCNPs could be quenched strongly by Cu2+ due to an energy transfer effect. Upon addition of AChE and acetylthiocholine (ATCh), the enzymatic hydrolysate (thiocholine) could seize Cu2+ from UCNPs-Cu2+ mixture, resulting in the quenched FL triggered on. OPs could irreversibly impede the activity of AChE, which caused the formation of thiocholine to decrease, thus, reduced the recovery of FL. Under the optimum conditions, a linear detection range from 0.1 to 50 ng/mL was achieved for the representative OPs (diazinon) with LOD of 0.05 ng/mL. Furthermore, the ability of the biosensor to detect OPs was also confirmed in adulterated environmental and agricultural samples. In validation analysis, the proposed sensor showed satisfactory results (p > 0.05) with GC–MS.
研究领域:
生物传感技术
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食品安全检测
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分析化学
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产品关联
DOI
PubMed
高影响因子
NEW JOURNAL OF CHEMISTRY
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2025
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IF 2.5
Xinyi Feng,Yuqing Fu,Zhanqiu Tang,Hongyuan Tian,Zhenglong Wu,Weidong Qin
Dichlorvos and Cr(VI) are widespread environmental contaminants that pose significant risks to water quality, ecosystems, and human health. Therefore, the development of rapid, sensitive, and reliable detection methods for these pollutants is critically important. Although various techniques have been employed for the individual detection of these substances, achieving simultaneous and selective detection of both remains a considerable analytical challenge. In this study, iron-doped poly(amidoamine) carbon dots (PAMAM-Fe CDs) were synthesized, exhibiting multiple enzyme-mimetic activities, including peroxidase-, oxidase-, superoxide dismutase-, and catalase-like functions. Notably, dichlorvos and Cr(VI) were found to selectively influence the catalase-like and oxidase-like activities, respectively. Based on these findings, a dual-mode fluorescence and colorimetric sensing platform was developed, enabling rapid, sensitive, and selective detection of dichlorvos and Cr(VI), with detection limits of 1.69 × 10⁻⁵ µg/mL and 0.0418 µM, respectively. The applicability of this platform was validated through analysis of real-world samples, demonstrating satisfactory recovery rates and reproducibility. This work not only establishes a new approach for detecting dichlorvos and Cr(VI) for food safety and environmental monitoring but also provides new insights into designing multienzyme-active nanomaterials with significant practical potential.
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产品关联
DOI
高影响因子
FOOD CHEMISTRY
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2020
·
IF 6.306
Yao Chen,Yanyan Zhu,Yuhui Zhao,Jing Wang
An efficient and convenient detection method for organophosphorus pesticide (OP) residues is needed because of their high neurotoxicity and severe threat to food safety. OPs effectively reduce the production of thiocholine in the acetylcholinesterase/acetylthiocholine reaction by inhibiting the activity of acetylcholinesterase. Therefore, we developed a feasible and convenient fluorescent and colorimetric dual-response sensor based on the competitive complexation of Cu 2+ between graphitic carbon nitride nanosheets and thiocholine for the rapid detection of OPs with high sensitivity. Malathion was used as a model OP, and a linear range of 70–800 nM with a detection limit of 6.798 nM for a fluorescent signaling platform and 2.5–25 nM with a detection limit of 1.204 nM for a colorimetric probe were attained. The constructed probe was successfully applied to determine OP in actual samples of cabbages leaves and tap water. The results indicated that the dual-response probe was reliable and sensitive to actual samples.
研究领域:
分析化学
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食品安全
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环境科学
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产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
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2021
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IF 7.46
Jun-feng Qi,Duo Tan,Xue-juan Wang,Hui-ting Ma,Ying-chun Wan,Ao Hu,Lin-hai Li,Bin Xiao,Bin Lu
Biosensors using acetylcholinesterase (AChE) as the recognition element detect both toxicity (AChE inhibition activity) and concentration of organophosphorus pesticides (OPs). However, real application of these biosensors remains a challenge due to their low selectivity and low resistance to sample matrix, interferences and hash analytical conditions. In this study, a novel dual-recognized strategy was established by using molecularly imprinted polymer (MIP) and AChE selective to different moieties of acephate (AP) as affinity molecules simultaneously. Using AP as the model OP, MIP highly selective to certain moieties but not phosphorus of AP was prepared on the surface of microplate by self-polymerization of dopamine. The MIP enriched AP from samples selectively. Then AChE selective to phosphorus of AP quantified the levels of AP captured by MIP. AP captured by MIP still inhibited the activity of AChE because the affinity of AP to AChE was higher than to MIP. By incorporating selective sample pretreatment with AChE inhibition assay in one sensor, the biosensor identified AP from other OPs, carbamates pesticides and interferences commonly found in food and environmental samples. When vegetables with high matrix effect on AChE inhibition assay were analyzed, selective sample pretreatment ensured the biosensor to detect AP more accurately and selectively than classical AChE inhibition assay. The results of the biosensor had no statistical difference compared with those of HPLC-MS/MS. The dual-recognized strategy may provide a new solution to detect target enzyme inhibitors in complicated samples using enzyme-based biosensors selectively and accurately.
研究领域:
生物传感技术
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分析化学
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产品关联
DOI
高影响因子
ELECTROANALYSIS
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2021
·Vol. 33
·期 9
·2048-2052
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IF 3.223
Lei Liu,Jiawei Guo,Longhua Ding
An electrochemical sensor based on raffia derived porous carbon (RPC) and polyaniline (PANI) composite functional glass carbon electrode (GCE) was constructed for imidacloprid (IMI) determination. PANI nanowire arrays were deposited on RPC surface uniformly without aggregations. The electrochemical response of IMI at RPC@PANI/GCE is about four times than that at bare GCE, indicating high electrocatalytic activity of RPC@PANI towards IMI reduction. The prepared sensor also offers a wide linear range of 0.1–70 μg mL −1 for IMI determination with a limit of detection (LOD) of 0.03 μg mL −1 . In addition, it offers high recoveries with testing real samples.
研究领域:
材料科学
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分析化学
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产品关联
DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
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2023
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IF 13.6
Guoxin Wu,Chuanqi Zhang,Chang Liu,Xiangzi Li,Yuanyuan Cai,Meifang Wang,Deqiang Chu,Liyun Liu,Tian Meng,Zhiming Chen
Organothiophosphate pesticides (OPPs) are the most common water contaminants, significantly endangering human health and bringing serious public safety issues. Thus, developing effective technologies for the removal or trace detection of OPPs from water is urgent. Herein, a novel graphene-based silica-coated core–shell tubular magnetic nanocomposite (Ni@SiO 2 -G) was fabricated for the first time and used for the efficient magnetic solid-phase extraction (MSPE) of the OPPs chlorpyrifos , diazinon , and fenitrothion from environmental water. The experimental factors affecting extraction efficiency such as adsorbent dosage, extraction time, desorption solvent, desorption mode, desorption time, and adsorbent type were evaluated. The synthesized Ni@SiO 2 -G nanocomposites showed a higher preconcentration capacity than the Ni nanotubes , Ni@SiO 2 nanotubes, and graphene. Under the optimized conditions, 5 mg of tubular nano-adsorbent displayed good linearity within the range of 0.1–1 μg·mL –1 , low limits of detection (0.04–0.25 pg·mL –1 ), low limits of quantification (0.132–0.834 pg·mL −1 ), good reusability (n = 5; relative standard deviations between 1.46% and 9.65%), low dosage (5 mg), and low real detection concentration (< 3.0 ng·mL −1 ). Moreover, the possible interaction mechanism was investigated by density functional theory calculation. Results showed that Ni@SiO 2 -G was a potential magnetic material for the preconcentration and extraction of formed OPPs at ultra-trace levels from environmental water.
研究领域:
环境科学
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材料科学
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分析化学
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产品关联
DOI
PubMed
高影响因子
ELECTROANALYSIS
·
2020
·Vol. 32
·期 8
·1834-1842
·
IF 2.544
Huaying Hu,Bo Wang,Yiru Li,Pengchang Wang,Lianqiao Yang
In this paper, novel and stable acetylcholinesterase (AChE) sensor with patterned structure for detecting organophosphorus pesticides (OPs) based on titanium dioxide sol-gel carrier was proposed and prepared. Biosensor was assembled by dropping titanium oxide, chitosan (CS) and enzyme to the surface of the glass carbon step by step. The concentration range of the sensor detection for dichlorvos (DDVP) is 1.13 nM to 22.6 μM, and the limit of detection (LOD) is 0.23 nM. It can also detect dichlorvos in cabbage juice samples accurately. The preparation of biosensor adopted a patterned novel structure for the first time, which opens a new way for the structure optimization of organophosphorus pesticide sensor.
研究领域:
生物传感技术
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环境科学
·
食品安全检测
✓ 已验证
产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
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2025
·
IF 5.1
Zhaoxiang Zhong,Bochi Pan,Yi Xing,Hanlin Xu,Min Zhang,Lei Ding,Faliang Cheng
The extensive global application of chlorpyrifos (CPF) has led to significant environmental accumulation through aquatic systems, presenting substantial risks to ecological integrity and public health. This urgency necessitates advanced detection methodologies with enhanced sensitivity and operational efficiency to ensure environmental safety. Here, we developed a novel photoelectrochemical aptamer sensor utilizing a MIL-101(Cr)&Bi 2 S 3 heterostructure composite. This architecture synergistically integrates the broad-spectrum photon absorption capability of Bi 2 S 3 with the hierarchical porosity and structural stability of MIL-101(Cr), achieving remarkable enhancement in both electron-hole separation efficiency and interfacial charge transfer. The sensing platform was further optimized through aptamer functionalization, which confers precise molecular recognition capabilities while maintaining optimal charge transfer dynamics at the electrode interface. Systematic evaluation demonstrated exceptional analytical performance: a linear detection range spanning four orders of magnitude (0.05–10 μg/mL), ultralow detection limit of 0.022 ng/mL (S/N = 3). The developed methodology provides a versatile framework for adapting to other organophosphorus pesticide detection requirements through modular aptamer replacement.
研究领域:
环境科学
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分析化学
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材料科学
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传感器技术
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纳米技术
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产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Jie Tang,Tingting Cai,Zexi Chen,Na Li,Jintong Liu,Hong Yang
The pervasive application of organophosphorus pesticides (OPs) in agriculture led to a persistent accumulation and causing environmental pollution and safety problems. In response, this study presented a Cu(II)-blocked aggregation-induced emission (AIE)-based metal organic framework (MOF) nanosystem for sensing diazinon. Based on the inhibition capability of diazinon on glutathione peroxidases, the oxidation and consumption of glutathione (GSH) was restricted. Owing to redox reaction between Cu(II) and abundant GSH relived by diazinon, the aggregation-induced emission luminogens (AIEgens) sealed in MOF could be released in aqueous solution and reassembled into emissive aggregates with significantly enhanced signals. The phase transformed-AIE fluorescence recovery provided sensitive diazinon detection method with a detection limit of 0.14 ng mL −1 , which was also reliable in food samples and bioaccumulation monitoring in rice. Thus, this work introduced a highly sensitive AIE-MOF-based fluorescence sensing approach for analyzing diazinon in crops, which was of significant importance for food safety and environmental monitoring.
研究领域:
分析化学
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环境科学
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食品科学
·
纳米技术
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农药检测
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）