DYES AND PIGMENTS
·
2021
·
IF 4.889
Yingying Zhang,Yanliang Zhao,Bo Song,Chaobo Huang
Acidic pH is an important physiological parameter in environment and biological systems. Thus, designing a probe ( Hcy-F ) with good characters to monitor acidic pH is really important. Herein, a small molecular water-soluble probe is designed based on indole with high selectivity and sensitivity for detection the acidic pH in aqueous solution and living cells. When pH variation of aqueous is detected by probe, an obvious ratiometric and good linear response behavior are found in UV–vis absorption spectrum (R 2 = 0.9973, A 434 nm / A 371 nm = 6.9929–4.2231 pH) and fluorescence emission spectrum (R 2 = 0.9987, I 571 nm / I 514 nm = 7.2935–2.981 pH), which further proved the feasibility of Hcy-F to monitor the change of acidic pH in aqueous, respectively. Furthermore, Hcy-F is successfully applied for monitoring pH variation in living cells in dual channels (green and red) with higher cell survival rate, indicating the probe has great potential for pH imaging in biological applications .
研究领域:
分析化学
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生物化学
·
细胞生物学
✓ 已验证
产品关联
DOI
高影响因子
Journal of Inorganic and Organometallic Polymers and Materials
·
2019
·Vol. 29
·期 6
·2124-2132
·
IF 1.637
Wang Zirui,Wang Xinyu,Li Jingfang,Li Weizuo,Li Guangming
In this work, a facile and fast luminescence sensing platform for the ratiometric detection of hydrogen sulfide (H 2 S/HS − ) has been constructed by encapsulating the Eu 3+ /β-diketone chromophore into the host framework of MIL-140 (Eu 3+ /TFA@MIL-140C, TFA = 1,1,1-Trifluoro-2,4-pentanedione). It is well known that the energy transfer from the host framework or/and TFA to the Eu 3+ ions can be disturbed easily by some metal ions, such as Cu 2+ ions. Therefore, the ratiometric sensor was constituted with the Eu 3+ /β-diketone moiety as the response signal and the host framework moiety as the reference signal. Furthermore, on the basis of the hard–soft acid–base theory, the Cu 2+ ions could be rapidly caught by HS − , profiting from the low solubility of CuS, realizing the real-time detection by luminescence color change. This sensor shows remarkable property on the detection of H 2 S (HS − in water solution) with low limit of detection (LOD = 7.43 μM) and short response time (< 0.5 min). The good linearity between luminescent intensity and concentration makes the luminescent ratio meter feasible.
研究领域:
材料科学
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分析化学
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环境科学
✓ 已验证
DOI
高影响因子
OPTICS LETTERS
·
2022
·Vol. 47
·期 23
·6293-6296
·
IF 3.56
Chongyang Cai,Leipeng Li,Pei Li,Tao Li,Dengfeng Peng,Yanmin Yang,Yanmin Yang
Mechanoluminescent materials have attracted considerable attention over the past two decades, owing to the ability to convert external mechanical stimuli into useful photons. Here we present a new, to the best of our knowledge, type of mechanoluminescent material, i.e., MgF2:Tb3+. In addition to the demonstration of traditional applications, such as stress sensing, we show the possibility of ratiometric thermometry using this mechanoluminescent material. Under stimulation of an external force, rather than the conventional photoexcitation, the luminescence ratio of 5D3→7F6 to 5D4→7F5 emission lines of Tb3+ is confirmed to be a good indicator of temperature. Our work not only expands the family of mechanoluminescent materials, but also provides a new and energy-saving route for temperature sensing.
研究领域:
材料科学
·
光学
✓ 已验证
DOI
PubMed
高影响因子
MICROPOROUS AND MESOPOROUS MATERIALS
·
2022
·
IF 5.876
Ning Wu,Hao Guo,Liping Peng,Yuan Chen,Lei Sun,Yinsheng Liu,Xiaoqing Wei,Wu Yang
Creatinine (Cre) measurement in biological fluids is an increasingly important clinical measure for evaluating renal insufficiency, thyroid dysfunction, and muscle injury. Therefore, a simple, fast, and reliable Cre analysis method is of great significance to human health. Herein, a novel ratiometric fluorescence sensor, Ag-Eu-MOF-808-EDTA, was synthesized by introducing ethylenediaminetetraacetic acid (EDTA), Ag + , and Eu 3+ into the framework of MOF-808 through three steps of post-synthesis modification, and was used to detect Cre in PBS buffer of pH 7.2 at 35 °C with a “turn-on” ratio response in the presence of various interfering ions and several biomolecules. In this strategy, the characteristic emission of Eu 3+ at 551 nm can be turned on due to coordination between Cre and Ag + , while emission at 613 nm is independent of Cre, which produces a significant ratio response change throughout the cycle. Experimental results showed that the ratio fluorescence sensor displayed a wide linear range for Cre from 0.5 to 350 μM with a low detection limit of 0.42 μM. Finally, a good recovery rate (96.7–102.9%) and appropriate relative standard deviation (RSD <2.39%, n = 3) were obtained during the determination of creatinine in real urine and serum. This work provides additional insights into the detection of creatinine in clinical blood samples.
研究领域:
分析化学
·
生物医学
✓ 已验证
产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2018
·
IF 5.667
Fanyong Yan,Zhangjun Bai,Yuan Chen,Fanlin Zu,Xing Li,Jinxia Xu,Liang Chen
A novel FRET ratiometric fluorescent probe (CMH-GA-CDs) was designed for the detection of Cu 2+ in aqueous solution. The CMH-GA-CDs were prepared through grafting 7-diethylaminocoumarin-3-carbohydrazide (HCM) on the surface of glyoxylic acid-modified carbon dots (GA-CDs) by amidation reaction. In the absence of Cu 2+ , a FRET pair from the CDs to CMH units was established, in which the CMH-GA-CDs exhibited dual emission bands centered at 400 nm (CDs) and 458 nm(CMH), respectively, under optimal excitation wavelength of CDs (λ ex = 340 nm). Upon addition of 30 μM Cu 2+ to CMH-GA-CDs solution, Cu 2+ coordinated with the heteroatoms N and O, which caused the inhibition of FRET process and the change of fluorescence intensity ratio I 458 /I 400 from 1.95 to 0.91. The ratio of I 458 /I 400 exhibited a good linear relationship with the concentration of Cu 2+ in the range of 0–10 μM and the limit of detection was as low as 0.21 μM. Furthermore, The CMH-GA-CDs were used for the detection of Cu 2+ in tap water and lake water with satisfactory recovery ratio between 91% and 104%, demonstrating the promising applicability for detecting Cu 2+ in water samples.
研究领域:
分析化学
·
材料科学
·
环境科学
✓ 已验证
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2021
·
IF 7.46
Yinghua Guo,Xinru Wang,Yan Feng,Xiao Luo,Xiangming Meng,Xuhong Qian,Youjun Yang
Autophagy is a physiological process governing proteostasis and implicated in many diseases. Enhanced ROS levels was known to be associated with lysosomal autophagy and therefore a lyso-specific ROS probe could find applications in autophagy related studies. Following the probe-design principle of bridging-group modification, we previously developed a ROS probe capable of detect a broader range of reactive species than the existing probes. Additional merits of the probe include ratiometry-capability, minimal probe-product spectral crosstalk, resistance toward autoxidation at lysosomal acidity, and structural simplicity. It is the aim of this manuscript to render this probe lyso-specificity and examine its potentials to monitor autophagy-related ROS generation in HeLa cells treated by H 2 O 2 or 6-OHDA.
研究领域:
细胞生物学
·
生物化学
·
医学研究
✓ 已验证
DOI
高影响因子
Journal of Environmental Sciences
·
2024
·
IF 5.9
Yongli Liu,Xiaoyan Su,Huanjia Liu,Guifen Zhu,Guobei Ge,Yuxin Wang,Penghui Zhou,Qingxiang Zhou
In present work, blue carbon dots (b-CDs) were derived from ammonium citrate and guanidine hydrochloride, and red carbon dots (r-CDs) were stemmed from malonate, ethylenediamine and meso‑tetra (4-carboxyphenyl) porphin based on facile hydrothermal method . Eco-friendly ratiometric fluorescence probe was innovatively constructed to effectively measure Hg 2+ utilizing b-CDs and r-CDs. The developed probe displayed two typical emission peaks at 450 nm from b-CDs and 650 nm from r-CDs under the excitation at 360 nm. Mercury ion has strong quenching effect on the fluorescence intensity at 450 nm due to the electron transfer process and the fluorescence change at 450 nm was used as the response signal, whereas the fluorescence intensity at 650 nm kept unchangeable which resulted from the chemical inertness between Hg 2+ and r-CDs, serving as the reference signal in the sensing system. Under optimal circumstances, this probe exhibited an excellent linearity between the fluorescence response values of ΔF 450 /F 650 and Hg 2+ concentrations over range of 0.01–10 µmol/L, and the limit of detection was down to 5.3 nmol/L. Furthermore, this probe was successfully employed for sensing Hg 2+ in practical environmental water samples with satisfied recoveries of 98.5%–105.0%. The constructed ratiometric fluorescent probe provided a rapid, environmental-friendly, reliable, and efficient platform for measuring trace Hg 2+ in environmental field.
研究领域:
分析化学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2024
·
IF 5.8
Zhou Yuan,Le Han,Yuchi Zhang,Lufang He,Peng Liu,Yan Xu
Self-assembled inorganic metal halide perovskite composites with high emitting efficiency, tunable multimode emission and stimuli-responsive luminescence demonstrated great potential in diversified luminescence applications. Here, a novel CsPbBr 3 /EuWO 4 (OH) composite was successfully prepared through the surface adsorption of Pb 2+ ions on hydroxylated EuWO 4 (OH) microsheets and subsequent nucleation of CsPbBr 3 peroviskite quantum dots (PQDs) by the anti-solvent crystallization in CsBr containing N,N-dimethylformamide (DMF) solution. Due to the distinct fluorescent thermochromic switching properties of temperature-insensitive Eu 3+ and sensitive CsPbBr 3 PQDs emitting centers, the resultant CsPbBr 3 /EuWO 4 (OH) composite exhibits excellent ratiometric temperature sensing performance. The CsPbBr 3 /EuWO 4 (OH) thermometer based on the fluorescence intensity ratio (FIR) technique originating from emissions of Eu 3+ to CsPbBr 3 PQDs was then explored with a high temperature sensitivity (S r ) of 5.8 % ℃ −1 at 54 ℃. In addition, a high-security-level information encryption scheme was proposed by utilizing the excitation-wavelength-dependent switchable fluorescence of CsPbBr 3 /EuWO 4 (OH) composite. This study provides a simple and feasible strategy for assembling dual-emission CsPbBr 3 /EuWO 4 (OH) composite, showing potential applications in optical ratiometric thermometry and information encryption fields.
研究领域:
材料科学
·
光学
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL SCIENCES
·
2024
·Vol. 40
·期 6
·1023-1030
·
IF 1.8
Zhang Yuecheng,Sun Lingbo,Li Chengjia,Ma Jing,Zhang Shiyu,Wang QingQing,Ma Hongyan
Dopamine (DA) is a neuromodulatory molecule that plays critical roles in many biological processes. The dysfunctions of the DA system are closely associated with several nervous system diseases. Therefore, it is urgent to establish a simple and accurate method for DA analysis. In this study, an economic and accurate DA ratiometric sensor was established using dual-emission carbon dots (DE-CDs). DE-CDs were first synthesized by the one-step solvothermal method and two separate fluorescence emission peaks at 340 and 500 nm were observed under the excitation of 310 nm. In the presence of Hg 2+ , the fluorescence signal at 340 nm was significantly quenched, while the signal at 500 nm keeps stable. Upon adding DA, the quenched signal at 340 nm was significantly recovered, whereas the signal at 500 nm remains stable. Therefore, a novel ratiometric sensor for DA analysis was established. This method shows a good linear range from 500 nM to 100 μM, and the detection limit was calculated to be 80 nM. Moreover, this established method shows excellent specificity and could be applied in real sample analysis, showing great potential for application in clinical research. Graphical abstract
研究领域:
分析化学
·
生物医学
✓ 已验证
DOI
PubMed
高影响因子
POLYHEDRON
·
2020
·
IF 2.343
Yin-Jing Shen,Kun Zhang
In this paper, we design and synthesize an N -linked disalicylaldehyde H 2 Q j1 based on the economical substrates, and it is composed of two identical salicylaldehyde moieties with the intramolecular ESIPT character. During the process of sensing heavy metal ions, it is found that the ESIPT state of H 2 Q j1 can be rapidly (60 s) destroyed by Fe(III) and Cu(II), resulting in the turn-off fluormetric and colorimetric responses. Serial fluorescence and absorption titration experiments reveal that the H 2 Q j1 -Fe(III) and H 2 Q j1 -Cu(II) sensing systems are ratiometric and their corresponding coordination modes are 1:1 and 2:1. Especially, their LOD values are as low as 0.40 μΜ and 0.21 μΜ which are comparable to reported examples. Moreover, we also develop a convenient technique to detect Fe(III) and Cu(II) using paper-based sensing devices together with smartphone-based RGB analysis method which will rapidly provide the precise determination results, even in the tap water sample. Therefore, this bifunctional disalicylaldehyde H 2 Q j1 is taken as a useable platform to monitor Fe(III) and Cu(II) and offers some valuable lights for further optical probes.
研究领域:
分析化学
·
光学传感
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF LUMINESCENCE
·
2019
·
IF 2.961
Lu Liu,Dongyang Tang,Li Xu,Fahim Khan,Isam Ud Din,Zhao Wang,Pengfei Li,Hanyang Li,Enming Zhao,Yang Zhang
Various concentrations of Ho 3+ and Nd 3+ codoped NaYF 4 nanorods were successfully synthesized. On the basis of the upconversion spectra under 808 nm excitation, the luminescence mechanisms were discussed in detail. The ratio of red to green intensity evidently increases with increasing the Nd 3+ content due to the stronger interactions between Ho 3+ and Nd 3+ , which enhance the red emission and suppress the green one. In addition, we found that the red emission is more sensitive to the ambient temperature as compared to the green one, thus validating the thermal sensing by applying the ratiometric method by using these two emission bands. Relatively high sensing sensitivity of 0.9% was obtained, evidencing the great potential of the presented optical thermometer.
研究领域:
材料科学
·
光学
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
Nanoscale
·
2019
·Vol. 11
·期 17
·8458-8463
·
IF 6.97
Haifang Liu,Yuanqiang Sun,Zhaohui Li,Jie Yang,Aaron Albert Aryee,Lingbo Qu,Dan Du,Yuehe Lin
Formaldehyde (FA) is involved in many biological processes and is closely connected with many diseases including Alzheimer's disease and cancer. Therefore, methods for sensitive and selective detection of FA in living cells are highly demanded. As a new class of carbon nanomaterials, carbon dots (CDs) have attracted great attention owing to their robust photostability, good biocompatibility and environmental friendliness. In this manuscript, the first lysosome-targeted CDs for ratiometric fluorescence detection of FA were efficiently prepared from dexamethasone and 1,2,4,5-tetraaminobenzene through the microwave-assisted hydrothermal method. These CDs show highly selective and sensitive sensing ability towards FA with fast response and great changes of ratio values. The CDs exhibit robust photostability and good biocompatibility and were successfully employed in ratiometric fluorescence bioimaging of FA fluctuations in lysosomes of living cells, which demonstrates their great practicability in FA-related bioanalysis and biological studies.
研究领域:
生物化学
·
纳米医学
·
分析化学
✓ 已验证
DOI
PubMed
高影响因子
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