INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY
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2022
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IF 2.731
Feng Yizhi,Zhang Aijuan,Pan Jinju,Zuo Bojun,Liang Lin
The aim of this study was to investigate the dissipation and residues of fluopyram in melon under field conditions and to assess its safe use. A liquid chromatography tandem mass spectrometry (LC-MS/MS) with QuEChERS for analysis of fluopyram and its metabolite M25 was established. Under the experimental condition of adding different levels of analytes (0.02 ~ 2 mg kg−1), the average residue recovery of fluopyram and M25 in melon was 96%~105% with a relative standard deviation of 2%~8%. The limit of quantitation of fluopyram and M25 in melon was 0.02 mg kg−1. Field trial results showed that the half-life of fluopyram in melon was 4.5–6.2 days, and the degradation was relatively fast. The residual of M25 in melon was lower than the LOQ. The terminal residues of fluopyram in melon sample were in the range of <0.02 ~ 0.095 mg kg−1, which was lower than the maximum residue limit for melon in EU (0.4 mg kg−1) and South Korea (0.6 mg kg−1). Dietary risk assessment indicated that the long-term intake risk quotient (rqchronic) and short-term intake risk quotient (rqacute) of fluopyram in people from different age groups were 0.000079 ~ 0.000671 and 0.002978 ~ 0.025268, respectively, which were significantly lower than 1. Therefore, the residues of fluopyram in melons would not affect the health of the general population in China.
研究领域:
植物保护学
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食品安全
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分析化学
✓ 已验证
产品关联
DOI
高影响因子
ACS Agricultural Science & Technology
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2024
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IF 2.3
Li Man,Huayao Chen,Xiang Liao,Jinhao Zhao,Hongjun Zhou,Li Hao,Xinhua Zhou
The low utilization rate of pesticide leads to the pollution of soil and environment, which ultimately endangers human health. In this study, TiO2 nanoparticles were synthesized and loaded with fluopyram (Flu) on halloysite (Ha) via sol–gel methods which was named Flu@THa. Thermogravimetric analysis (TGA), Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM) were used to characterize the structure of all samples, and then the performances of zeta potential, fungistatic ability, antileaching behavior, and biosafety were tested. The results showed that anatase-phase TiO2 was synthesized on halloysite with a particle size of ∼10 nm. Under neutral conditions (pH 7), the cumulative rate of pesticide release from Flu@THa was three times higher than that under acidic and alkaline conditions in 24 h. Flu@THa was evenly distributed in the soil and slowed the loss of pesticides. In addition, Flu@THa can promote germination and growth of peanut seeds and had good biocompatibility with low toxicity to zebrafish. This study is expected to be able to provide implications for environmentally friendly nanopesticides.
研究领域:
环境科学
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农业科学
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材料科学
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产品关联
DOI
高影响因子
MOLECULES
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2021
·Vol. 26
·期 11
·3344
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IF 4.412
Shunyu Yao,Zixi Zhao,Wang Lu,Xin Dong,Jiye Hu,Xiaolu Liu
The chemical fungicide fludioxonil is widely used to control post-harvest fungal disease in cherries. This study was implemented to investigate the dissipation behaviours and residues of fludioxonil on cherries. A reliable and efficient analytical method was established. Cherry samples from four product areas were analyzed by QuEChERS and HPLC-MS/MS methods with acceptable linearity (R2> 0.99), accuracy (recoveries of 81–94%), and precision (relative standard deviation of 2.5–11.9%). The limits of quantification (LOQs) and limits of detection (LODs) of cherries were 0.01 mg/kg and 0.005 mg/kg. The dissipation of fludioxonil on cherries followed first order kinetics with half-lives of 33.7–44.7 days. The terminal residues of fludioxonil were all lower than 5.00 mg/kg, which is the MRL recommended by the European Commission. According to Chinese dietary patterns and terminal residue distributions, the risk quotient (RQs) of fludioxonil was 0.61%, revealing that the evaluated cherries exhibited an acceptably low dietary risk to consumers.Keywords:fludioxonil;cherry;HPLC-MS/MS;dissipation behaviour;residues;dietary risk assessment
研究领域:
食品科学
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农业化学
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毒理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2024
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IF 4.3
Kexiang Li,Hong Li,Qian Zhang,Dezhi Yang,Yaling Yang
In this work, a facile synthesis method for dopamine carbon dots-based Au nanoparticles (DA-CDs/AuNPs) by seed gold method was reported as the surface enhanced Raman scattering (SERS) booster. DA-CDs with rich in surface functional groups was synthesized using dopamine, citric acid and ethylenediamine as precursors by a facile hydrothermal method, and can be used as the capping agents and reducing agents for the synthesis of DA-CDs/AuNPs. Due to the electromagnetic “hot spots” effect, DA-CDs/AuNPs with core–shell structure exhibited strong SERS activity. Based on the specific interaction of DA-CDs/AuNPs and fenamidone, a detection method of fenamidone was established with a low detection limit of 0.05 μg/mL. Finally, the SERS sensor was successfully applied to the detection of fenamidone in fruit with recoveries between 90.6 % and 98.7 %. The method here proposed can be reliably applied for fenamidone detection on fruits.
研究领域:
材料科学
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分析化学
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纳米技术
✓ 已验证
DOI
高影响因子
Journal of Saudi Chemical Society
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2024
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IF 5.8
Yong Zhang,Mei Zhu,Kun Hu,Xing Liu,Yue Zou,Jixiang Chen
Fluopyram is a highly effective agricultural fungicide targeting succinate dehydrogenase (SDH). Twenty-six novel amide derivatives containing azetidine were designed and synthesized with fluopyram as the lead, and their biological activities were tested. The results showed that some compounds had obvious antifungal activities against Phomopsis sp., among them, the EC 50 value of compound C24 was 5.7 mg/L, which was significantly better than fluopyram (105.4 mg/L). The curative and protective activities of compound C24 on kiwi fruit infected with Phomopsis sp. were 42.2 and 52.9 %, which were better than that of fluopyram (30.4 and 35.6 %) at 200 mg/L. Moreover, compound C24 exhibited excellent inhibitory against SDH. The results of scanning electron microscopy (SEM) indicated that the mycelium of Phomopsis sp. collapsed or even ruptured after compound C24 treatment. Meanwhile, molecular docking showed that compound C24 was deeply embedded into the SDH binding pocket, and the binding model was stabilized by a cation–π interaction with Cys-40, Tyr-58 and an H-bond with Lys-455 and Asn-452. Compound C24 can provide a valuable idea to find new succinate dehydrogenase inhibitors.
研究领域:
农业化学
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药理学
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真菌学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）