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International Journal of Electrochemical Science · 2023 ·Vol. 7 ·期 6 ·5172-5184 · IF 1.5

Reduction of Graphene Oxide Via Ascorbic Acid and Its Application for Simultaneous Detection of Dopamine And Ascorbic Acid

Xu Zhu,Qin Liu,Xiaohua Zhu,Chunlan Li,Maotian Xu,Yong Liang

A new approach to synthesize graphene was applied by reduction of graphene oxide using ascorbic acid. Chitosan/graphene modified electrode could be employed for simultaneous determination of dopamine and ascorbic acid. The modified electrode showed excellent electrocatalytic activity towards the oxidation of DA and AA. The calibration curves for DA and AA were obtained in the range of 0.3-1067.5μM and 0.6-1378.1μM, respectively. Detection limits were 0.1μM and 0.01μM for DA and AA, respectively. The present method was applied to the determination of AA and DA in human serum samples and the results were quite promising.

研究领域: 分析化学 · 电化学 · 生物传感器 · 纳米材料 · 临床检验 · 神经化学 · 药物分析
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