Materials
·
2025
·Vol. 18
·期 5
·1131
·
IF 3.2
Tian Zhao
HKUST-1 (HKUST = Hong Kong University of Science and Technology) is one of the most recognized metal-organic frameworks (MOFs) based on copper and trimesate, extensively studied for a variety of applications, such as gas storage, separation, adsorption, electrocatalysis, drug delivery, sensor and photodegradation, etc. In this work, we introduce a novel nanofused HKUST-1, referred to as N-CuBTC (BTC = trimesate), which has been synthesized with the hydrothermal method at room temperature (typical synthesis temperature is from 80~120 °C). The resulting N-CuBTC features an irregular particle morphology, with numerous crystals clustering together and edges that have fused, creating a hierarchical pore structure. In contrast to the traditional micro-sized octahedral HKUST-1 (named as M-CuBTC), N-CuBTC displays a unique clumped morphology, where the HKUST-1 crystals are seamlessly integrated into a cohesive structure. This innovative formation significantly enhances mass transfer capabilities and porosity accessibility. Consequently, N-CuBTC demonstrates markedly improved catalytic performance in the cyanosilylation of aldehydes.
研究领域:
材料科学
·
催化化学
✓ 已验证
DOI
PubMed
高影响因子
SYNTHETIC COMMUNICATIONS
·
2013
·
IF 1.06
Xuerui Zhang,Guoping Yong,Wenlong She
The potassium metal can promote direct arylation of unactivated aromatic C-H bonds under an oxygen atmosphere. Interestingly, in situ demethoxylation, dechloridation, or decyanogenation from the corresponding coupling aromatic compounds mediated by potassium metal was also observed in the radical reaction systems.
Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications® for full spectral details.
研究领域:
有机化学
·
合成化学
✓ 已验证
产品关联
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2021
·
IF 4.098
Hongyu Guo,Jianrong Lin,Linlu Zheng,Fafu Yang
Although some reports on sensing ClO − had been presented, the ClO − sensor with high selectivity and sensitivity in aqueous media was still expected. Herein, an effective fluorescent sensor for ClO − in aqueous media was designed and synthesized by simple procedure based on cyanostilbene derivative ( TCS ). TCS exhibited strong fluorescence in aqueous media, which could be selectively quenched by ClO − among various species. The detection limit was as low as 3.2 × 10 −8 M. The sensing mechanism of the oxidation of sulfur in thiophene unit was confirmed by the FT-IR spectrum, fluorescence Job’s plot, 1 H NMR spectrum and MS spectrum. This sensor was successfully applied on detecting ClO − in real sample and living-cell imaging, suggesting its potential application for sensing ClO − in both vitro assay and vivo environment.
研究领域:
分析化学
·
生物医学
·
环境科学
✓ 已验证
DOI
PubMed
高影响因子
MACROMOLECULES
·
2015
·
IF 5.8
Jia-Li Chen,Li Yang,Qian Wang,Zhi-Qiang Jiang,Na Liu,Jun Yin,Yunsheng Ding,Zong-Quan Wu
Polymerization of phenyl isocyanide using achiral Pd(II) initiator with the presence of chiral l- or d-lactide (l-LA or d-LA) as additive was found to proceed in helix-sense-selective manner. The polymerization of achiral phenyl isocyanide, 4-isocyanobenzoyl-2-aminoisobutyric acid decyl ester (1) by this method produced optically active helical poly-1m(L), whose chirality was solely come from the helical conformation without containing of any other chiral atoms. The added chiral LA can be facilely recovered and reused in the helix-sense-selective polymerizations without significantly loss of its chiral induction, and the chiral economy of the polymerization is high. When enantiomerically pure phenyl isocyanide bearing an R- or S-alanine pendent with a long n-decyl chain (1r or 1s) were polymerized by this method, the polymerization was found to proceed in a highly enantiomer-selective manner with one of the enantiomers preferentially polymerized over the antipode by a factor of 3.6. Single-handed helical polyisocyanides can be achieved when the chirality of the monomer was appropriately matched with the added LA.
研究领域:
高分子化学
·
有机化学
✓ 已验证
DOI
高影响因子
GREEN CHEMISTRY
·
2025
·
IF 9.2
Yukun Zhang,Chong Chen,Changjiang Hu,Jianfeng Zhao,Jun Ma
Photoreduction conversion of soluble U(VI) to insoluble U(IV) is regarded as an ideal strategy for removing uranium from water. The Cyanide-based photocatalysts shows promises for efficient uranium removal but their green synthesis remain significant challenges. Herein, we develop a γ-irradiation-induced strategy for in-situ -CN generation via imidazole ring opening in ZIF-8 MOFs for uranium photoreduction, circumventing the use of toxic cyanide sources. In-situ transmission electron microscopy (TEM) and in-situ X-rays coupled diffraction infrared Fourier transform (DRIFT) reveal morphological evolution via imidazole ring cleavage and -CN formation kinetics during irradiation. Research indicated that -CN-functionalized ZIF-8 displayed superior uranium photoreduction activity through -CN-UO22+ complexation and promotion of photo-induced electron transfer. Impressively, the uranium extraction capacity reached a value of 1532.4 mg/g, higher than most existing MOF-type photocatalysts. In-situ DRIFT spectroscopy revealed the intermediates of the photoreduction uranium reaction and their adsorption mode with the catalyst, providing a comprehensive mechanistic explanation. This work provides a sustainable pathway for uranium photoreduction and guidance for the green design of MOF-type photocatalysts.
研究领域:
环境科学
·
核化学
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材料化学
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光催化
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放射化学
✓ 已验证
产品关联
DOI
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2022
·Vol. 32
·期 16
·2111043
·
IF 19.924
Yifan Wang,Preeyaporn Poldorn,Yutthana Wongnongwa,Siriporn Jungsuttiwong,Chong Chen,Le Yu,Zhuyi Wang,Liyi Shi,Yin Zhao,Shuai Yuan
Organic cathode materials are plagued by their low cycle stability and poor electronic conductivity, even though they have attracted increasing attention in the context of lithium-ion batteries (LIBs). Herein, a coordination polymer cobalt-hexaazatriphenylene hexacarbonitrile (Co(HAT-CN)) is prepared via a facile solvothermal method, which is composed of the redox-active HAT-CN linker and the Co(II) ion center. The fabricated material shows excellent structural stability and high conductivity. Moreover, graphene oxide (GO) is introduced as a substrate, and in-situ loading of Co(HAT-CN) on its surface shows enhanced cycling stability. For Co(HAT-CN)/GO, a high specific capacity of 204 mAh g –1 can be retained even after 200 cycles at a current density of 40 mA g –1 in a voltage window of 1.2–3.9 V. Ex situ and in situ analyses are applied to probe the reversibility of the pyrazine redox-active center during the cycling process and the lithium storage process. Density functional theory calculations reveal that the high conductivity of Co(HAT-CN) should be ascribed to the narrow LUMO-HOMO gap (0.61 eV), and strong binding of lithiated molecules.
研究领域:
材料科学
·
能源存储
✓ 已验证
产品关联
DOI
高影响因子
DRUG METABOLISM AND DISPOSITION
·
2024
·Vol. 52
·期 7
·597-605
·
IF 4.4
Ting Wu,Lu Li,Wenhong Zhou,Guofang Bi,Xiaowen Jiang,Manlan Guo,Xiao Yang,Jianhong Fang,Jianxin Pang,Shicheng Fan,Huichang Bi
Pregnane X receptor (PXR) is essential in the regulation of liver homeostasis, and the gut microbiota is closely linked to liver physiologic and pathologic status. We previously found that activation of PXR significantly promotes liver enlargement through interaction with yes-associated protein (YAP). However, whether gut microbiota contributes to PXR-induced hepatomegaly and the involved mechanisms remain unclear. In this study, C57BL/6 mice were administered the mouse-specific agonist pregnenolone 16α-carbonitrile (PCN) for 5 days. Depletion of gut microbiota was achieved using broad-spectrum antibiotics (ABX) and fecal microbiota transplantation (FMT) was performed to restore the gut microbia. The composition of gut microbiota was analyzed by 16S rRNA sequencing, while the expression of PXR, YAP, and their downstream target genes and proteins were assessed. The results indicated that PCN treatment altered the composition and abundance of specific bacterial taxa. Furthermore, depletion of gut microbiota using ABX significantly attenuated PCN-induced hepatomegaly. FMT experiments further demonstrated that the fecal microbiota from PCN-treated mice could induce liver enlargement. Mechanistic studies revealed that ABX treatment impeded the PXR and YAP activation induced by PCN, as evidenced by decreased expression of PXR, YAP, and their downstream targets. Moreover, alterations in PXR and YAP activation were likely contributing to hepatomegaly in recipient mice following FMT from PCN-treated mice. Collectively, the current study demonstrated that gut microbiota is involved in PCN-induced hepatomegaly via regulating PXR and YAP activation, providing potential novel insights into the involvement of gut microbiota in PXR-mediated hepatomegaly.
研究领域:
药理学
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微生物学
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肝脏病学
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分子生物学
✓ 已验证
DOI
PubMed
高影响因子
Nature Communications
·
2023
·Vol. 14
·期 1
·1-13
·
IF 16.6
Luo Huihui,Tian Shuainan,Liang Hongliang,Wang He,Gao Shuang,Dai Wen
The cleavage and functionalization of C–S bonds have become a rapidly growing field for the design or discovery of new transformations. However, it is usually difficult to achieve in a direct and selective fashion due to the intrinsic inertness and catalyst-poisonous character. Herein, for the first time, we report a novel and efficient protocol that enables direct oxidative cleavage and cyanation of organosulfur compounds by heterogeneous nonprecious-metal Co-N-C catalyst comprising graphene encapsulated Co nanoparticles and Co-Nx sites using oxygen as environmentally benign oxidant and ammonia as nitrogen source. A wide variety of thiols, sulfides, sulfoxides, sulfones, sulfonamides, and sulfonyl chlorides are viable in this reaction, enabling access to diverse nitriles under cyanide-free conditions. Moreover, modifying the reaction conditions also allows for the cleavage and amidation of organosulfur compounds to deliver amides. This protocol features excellent functional group tolerance, facile scalability, cost-effective and recyclable catalyst, and broad substrate scope. Characterization and mechanistic studies reveal that the remarkable effectiveness of the synergistic catalysis of Co nanoparticles and Co-Nx sites is crucial for achieving outstanding catalytic performance.
研究领域:
催化
·
有机化学
·
材料科学
·
环境化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）