APPLIED CATALYSIS A-GENERAL
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2025
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IF 4.8
Xiao Du,Tengfei Li,Lumei Wang,Dezhang Ren,Wenhui He,Zhibao Huo
In this paper, an alkali-free route for the conversion of chitin and shrimp shell to acetic acid (AA) using aluminum salts in aqueous media was reported for the first time. The proposed method demonstrated several advantages, including simplicity, effectiveness, and superior environmental and economic benefits compared to previous approaches. Notably, it achieved a significant breakthrough in the yields of AA derived from chitin and shrimp shells. Under the optimal conditions, the yield of AA reached the maximum value of 81.4 %. Combined with theoretical calculation and characterization, a possible transformation mechanism was proposed, and it was proved that the presence of aluminum salts would change the main reaction pathway and participate in the preparation of AA in the form of polymers. This study provided a novel idea for the resource utilization of chitin and waste shell materials into valuable chemicals and also for the treatment of environmental pollution.
研究领域:
生物化学
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环境科学
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材料科学
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产品关联
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2020
·
IF 3.232
Shibing Chen,Shengjie Jiang,Hongyu Guo,Fafu Yang
Previously reported fluorescent sensors for Th 4+ experienced emission quenching or generated false positive signal upon aggregate formation in aqueous media. Herein, a simple and novel thorium sensor ( CDB-BA ) based on cyanodistyrene structure was designed and synthesized, which integrated the highly emitting characteristic of AIE effect and off-on response of PET modulation for the first time to construct the “turn-on” fluorescent probe for Th 4+ . Besides excellent selectivity, CDB-BA exhibited remarkable fluorescent enhancement which was linearly related to the concentration of Th 4+ in the range of 0.25–8 μM. The detection limit was attained 0.074 μM, which was lower than that of most previously reported sensors. The mechanism of tris-chelate complex of CDB-BA with Th 4+ was confirmed by mass spectra, IR spectra and DFT calculation. The excellent Th 4+ sensing ability of CDB-BA was successfully applied to detecting Th 4+ on TLC plates, in real water samples and living-cell imaging. This work suggested that the combination of AIE and PET photophysical mechanism could offer the merits of minimized background and enhanced signal fidelity to develop novel “turn-on” fluorescent probe in complicated aqueous environment and biological research.
研究领域:
化学
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生物医学
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DOI
PubMed
高影响因子
RSC Advances
·
2019
·Vol. 9
·期 29
·16701-16712
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IF 3.049
Xiaofeng Li,Maohua Ma,Xuan Xin,Yuqian Tang,Guanglei Zhao,Xinglong Xiao
Gastrodin, a bioactive compound extracted from the plant source of Gastrodia elata Blume, has a wide range of therapeutic effects on central nervous system (CNS) diseases, but suffers from poor brain permeability and short half-life in plasma. In this study, fatty acid esters of gastrodin were successfully synthesized by a whole cell-based biocatalytic method. Aspergillus oryzae cells showed different catalytic activities in the organic solvent systems tested. Tetrahydrofuran was confirmed as the most suitable pure organic solvent, with the highest substrate conversion of 98.0%. Addition of ionic liquids (ILs) into pyridine dramatically accelerated the reaction with conversion increased from 5.9% to 84.2%, and also changed the selectivity of the cells, mainly due to the use of IL-containing systems altering cell permeability and contact of the enzymes with solvent molecules possessing different polarities. The ester products were characterized by 13C-NMR and ESI-MS as gastrodin monoester and diester.
研究领域:
药理学
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生物催化
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神经科学
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产品关联
DOI
PubMed
高影响因子
BIOCATALYSIS AND BIOTRANSFORMATION
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2025
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IF 1.9
Shenhan Xie,Yanyang Sun,Xu Yan,Yu Han,Chunyu Wang,Fengxi Li,Lei Wang,Zhi Wang
An efficient and environmental method was employed to synthesize multi-substituted 2H-pyran from methyl coumalate and β-keto esters or diketones. Porcine pancreas lipase (PPL) can catalyze this transformation in high yields (74–96%) in aqueous medium (H2O: DMSO = 2:1) under mild conditions (60 °C). The reported strategy exhibits high functional group compatibility and broad substrate scope. In addition, it provides access to a variety of tetra-substituted 2H-pyrans which are considered privileged scaffolds with diverse biological activities.
研究领域:
有机化学
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生物催化
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药物化学
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DOI
高影响因子
Journal of Materials Chemistry B
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2019
·Vol. 7
·期 30
·4620-4629
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IF 5.047
Lingjie Hou,Fan Li,Jinchang Guo,Xiaoying Zhang,Xiangyu Kong,Xinyan Tracy Cui,Chuan Dong,Yu Wang,Shaomin Shuang
A novel probe, 3-benzyl-2-(N-ethylcarbazole-3-vinyl)-benzothiazolium bromide (L), was synthesized and utilized for the specific detection of cyanide ions in neutral aqueous solution (HEPES buffer, pH 7.4). This probe displays a fast response through visible colorimetric and fluorogenic changes toward CN−, allowing for ratiometric sensing of cyanide in aqueous media. The ratiometric response is due to the breaking of the extensive π-conjugation and the intramolecular charge transfer (ICT) by the nucleophilic conjugation addition of cyanide to L, which is ascertained by NMR and ESI-MS analysis as well as density functional theory (DFT) calculations. The detection limit of CN− (3.39 × 10−7 M) is well below the limit recommended in the World Health Organization (WHO) guidelines for drinking water. Moreover, fluorescence co-localization studies demonstrate that L is a specific mitochondria-targeting fluorescent probe. As far as we are aware, compound L is the first mitochondria-targeting probe for cyanide detection and can be used for sensing CN− in living cells with dual channel ratiometric fluorescence imaging.
研究领域:
分析化学
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生物成像
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毒理学
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DOI
PubMed
高影响因子
MACROMOLECULAR CHEMISTRY AND PHYSICS
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2015
·Vol. 216
·期 6
·671-677
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IF 2.616
Yuecheng Qian,Xiaojun Huang,Zhikang Xu
A green route is reported for functionalizing polyphosphazene via the thiol-ene click reaction in an aqueous medium. Poly[bis(allylamino)phosphazene] is used as the precursor polymer, which is easily dissolved in water containing 5% (v/v) phosphoric acid, but barely dissolved in other acidic aqueous solutions with the same pH value. Three thiol reagents, namely, 3-mercapto-1,2-propanediol, 2-mercaptoethoxy ethanol, and l -cysteine, are then reacted with the precursor in the phosphoric acid aqueous solutions. 1 H and 31 P NMR analyses confirm that the allyl polyphosphazene can be quantitatively modified by the mercaptans without hydrolysis degradation during the synthesis and purification processes. Moreover, these polyphosphazenes exhibit higher regioselectivity than those functionalized in organic solvents. This method provides a facile route for the green synthesis of functional polyphosphazenes without organic solvents.
研究领域:
材料化学
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绿色化学
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产品关联
DOI
高影响因子
TALANTA
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2019
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IF 4.916
Shengnan Wang,Xu Chu,Xiaoyan Xiang,Yan Cao
This study focused on the fluorescence antenna-sensitizing effect of graphene quantum dots (GQDs) in a case on the detection of terbium ions. A simple one-step chemical oxidation method was applied for the preparation of GQDs starting from the regular multilayer graphene oxide (GO) via the refluxing in a concentrated mixture of strong acids. The as-prepared GQDs were further evaluated as a fluorescent sensitizer to the terbium ion. An expanded in-deep mechanism study on the fluorescence phenomena during the interaction of the as-prepared GQDs and REEs was made. The highly selective antenna effect of GQDs on one of REEs’ aqueous media, which was terbium (III), was identified. The excited terbium ion emitted its long-living fluorescence based on its own characteristic line-typed f-f transition, contrasting to a undetectable fluorescence in a very poor quantum yield in its aqueous solution induced by water collisions. This study, in the first place, identified the significant sensitization effect of the as-prepared GQDs on the terbium ion in a high selectivity in aqueous media. The detectable linear range and the detection limit of the terbium ion was 0–30 × 10 −6 mol L −1 (R 2 = 0.9960) of 0.3 × 10 −6 mol L −1 , respectively. The excitation wavelength and the optimal fluorescence wavelength were 230 nm 546 nm, respectively. Further material characterizations, involving XPS, FTIR, Raman and the Zeta potential , verified the important participation of carboxyl function groups on the as-prepared GQDs.
研究领域:
材料科学
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分析化学
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产品关联
DOI
PubMed
高影响因子
POLYMER INTERNATIONAL
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2011
·Vol. 60
·期 10
·1455-1460
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IF 2.056
Xiuling Ma,Zhen Chen,Riyao Chen,Xi Zheng,Xiao Chen,Ruifang Lan
The objective of this study was to identify a kind of molecular imprinting polymer (MIP) which was suitable for recognizing naringin (NG) in aqueous medium. Based on two crosslinkers (hexamethylene diisocyanate and epichlorohydrin) and two polymerization methods (solution polymerization and emulsion polymerization), four non-covalent naringin-β-cyclodextrine (NG-β-CD) imprinted polymers were prepared by using β-CD as a functional monomer and NG as a template molecule. The binding property and selectivity were evaluated by equilibrium binding experiments. These demonstrated that all the sites in the MIPs show good selective binding ability for NG from naringin dihydrochalcone, a structurally similar molecule. Of the four MIPs, rod-like 3# MIP which was prepared by emulsion polymerization using hexamethylene diisocyanate as crosslinker exhibited the highest selectivity, its imprinting factor α being 1.53. Scatchard analysis of 3# MIP suggests that there are two classes of binding sites during the MIP's recognition of NG. Additionally, the 3# MIP could be used at least five times without any loss in sorption capacity. Copyright © 2011 Society of Chemical Industry
研究领域:
化学
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材料科学
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产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
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2018
·
IF 6.735
Ce-Ce Hu,Qiang Gao,Shu Liu,Li-Li Chang,Kai-Sheng Xia,Bo Han,Cheng-Gang Zhou
Recognition, quantification, and selective removal of target heavy metal ion with a single material are of great practical importance, while there still remains a formidable challenge of accomplishing these multiple tasks in pure aqueous media. Herein, we utilized crosslinked poly(ionic liquid) as support of organic probe to devise a new class of multifunctional material for addressing this issue while simultaneously providing some additional benefits. To illustrate this strategy, an imidazolium-type crosslinked poly(ionic liquid) anchored with rhodamine derivative, P(RhBHSA–BVD), was designed and applied for qualitative/quantitative analysis and selective removal of Cu 2+ . In significant contrast from previously reported organic probe/support composites that were typically hydrophobic and usually required use of organic solvent to disperse them before use, the P(RhBHSA–BVD) was highly hydrophilic and readily dispersed in pure water. Moreover, due to the positively charged nature of polymeric backbone, the P(RhBHSA–BVD) had a potential advantage of avoiding non-receptor binding. Observation with naked eye confirmed the highly selective and sensitive response of P(RhBHSA–BVD) to Cu 2+ , and accordingly a convenient colorimetric sensing method for detection of Cu 2+ was successfully established. Furthermore, it was demonstrated that the P(RhBHSA–BVD) could selectively remove Cu 2+ from multi-ions solution with high efficiency and excellent reusability.
研究领域:
材料科学
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环境科学
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分析化学
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产品关联
DOI
高影响因子
RSC Advances
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2015
·Vol. 5
·期 117
·96905-96910
·
IF 3.84
Xueyi Sun,Yu Wang,Xiaofeng Zhang,Shihong Zhang,Zhao Zhang
The optical behavior of a simple intramolecular charge transfer (ICT) fluorescent probe, a coumarin-nitrobenzene conjugate (CNB), has been described to detect cyanide (CN−) selectively in buffered aqueous media. The cyanide addition on the electron-deficient alkene bridge interrupts the π-conjugation in CNB, which obstructs the ICT process and results in a color change from yellow to colorless and a significant fluorescence enhancement at 410 nm. Job's plot analysis revealed a 1 : 1 stoichiometry for the interaction between the probe and cyanide anion with a detection limit of 0.14 μM. The probe was also used for fabrication of test strips that could be used in practical and efficient CN− test kits.
研究领域:
分析化学
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环境科学
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产品关联
DOI
高影响因子
Journal of Materials Chemistry B
·
2013
·Vol. 1
·期 38
·5014-5020
·
IF 0
Wei Lu,Jinting Zhou,Keyuan Liu,Dan Chen,Liming Jiang,Zhiquan Shen
A new kind of hydrophilic copolymer poly(HEMA-co-VNP) was designed and synthesized by the radical copolymerization of 2-hydroxyethylmethacrylate (HEMA) and 2-{[2-(4-vinylbenzyloxy)naphthalen-1-yl]methyleneamino}-(S)-2-phenylethanol (VNP). The desired copolymer showed a highly selective red-shifted emission and a unique chiroptical response upon HSO4− binding in organic solution. UV-vis and 1H NMR spectroscopic studies revealed that the hydrogen bonding between the imine moiety in the VNP repeating units and HSO4− is crucial for the high selectivity of the receptor to this anion. As expected, the incorporation of HEMA into the polymer matrix endowed the copolymer excellent hydrophilicity, flexibility and good film-forming properties. Thus, high-quality film sensors could be easily fabricated on quartz plates through spin-casting techniques. The resultant polymeric films can recognize HSO4− ions among a series of common anions in aqueous solution with high selectivity and sensitivity. The promising new film probe for HSO4− has distinct characteristics such as a rapid response, enough stability in an aqueous media and practicality.
研究领域:
材料科学
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分析化学
✓ 已验证
产品关联
DOI
PubMed
SENSORS AND ACTUATORS B-CHEMICAL
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2018
·
IF 5.667
Xiaojie Ren,Huihui Tian,Liu Yang,Long He,Yani Geng,Xingjiang Liu,Xiangzhi Song
Cysteine (Cys), homocysteine (Hcy), and glutathione (GSH) are of great importance in many physiological and pathological processes. Due to their similar structure and reactivity of these three biothiols, it is a great challenge to simultaneously distinguish one from another. By virtue of two different fluorescence signals, nitrobenzofurazan ( NBD ) has been proved to be an effective sensing functional group as well as a green fluorophore precursor to construct fluorescent probes for simultaneous discrimination of Cys/Hcy and GSH. However, most of the reported NBD-based fluorescent probes suffered from a poor water-solubility, a slow response, double-wavelength excitation or two interfering fluorescence signals (narrow wavelength separation in λ max Em and/or big difference in Φ Fl ). In this study, we developed a fluorescent probe, MCQ-O-NBD , for simultaneous discrimination of Cys/Hcy and GSH using two matched fluorescent signals (well separated red and green fluorescence and comparable Φ Fl ), which could function in a pure aqueous media with a rapid response under a single-wavelength excitation. This probe exhibited high sensitivity and good selectivity as well as low detection limit, and had been successfully applied to visualize and differentiate Cys/Hcy and GSH in living cells.
研究领域:
生物化学
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医学检测
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荧光成像
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DOI
高影响因子
危险品化学品经营许可证（带存储）