Applied Sciences-Basel
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2018
·Vol. 8
·期 12
·2530
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IF 1.689
Nan Fang Nie,Xin Xing Zhang,Chu Shan Fang,Qiu Yan Zhu,Jiao Yang Lu,Fu Rui Zhang,Qing Feng Yao,Wei Tao Huang,Xue Zhi Ding,Li Qiu Xia
Game theory—the scientific study of interactive, rational decision making—describes the interaction of two or more players from macroscopic organisms to microscopic cellular and subcellular levels. Life based on molecules is the highest and most complex expression of molecular interactions. However, using simple molecules to expand game theory for molecular decision-making remains challenging. Herein, we demonstrate a proof-of-concept molecular game-theoretical system (molecular prisoner’s dilemma) that relies on formation of the thymine–Hg2+–thymine hairpin structure specifically induced by Hg2+and fluorescence quenching and molecular adsorption capacities of cobalt oxyhydroxide (CoOOH) nanosheets, resulting in fluorescence intensity and distribution change of polythymine oligonucleotide 33-repeat thymines (T33). The “bait” molecule, T33, interacted with two molecular players, CoOOH and Hg2+, in different states (absence = silence and presence = betrayal), regarded as strategies. We created conflicts (sharing or self-interest) of fluorescence distribution of T33, quantifiable in a 2 × 2 payoff matrix. In addition, the molecular game-theoretical-system based on T33 and CoOOH was used for sensing Hg2+over the range of 20 to 600 nM with the detection limit of 7.94 nM (3σ) and for determination of Hg2+in pond water. Inspired by the proof-of-concept for molecular game theory, various molecular decision-making systems could be developed, which would help promote molecular information processing and generating novel molecular intelligent decision systems for environmental monitoring and molecular diagnosis and therapy.Keywords:cobalt oxyhydroxide nanosheets;fluorescent sensing;game theory;Hg2+;thymine–Hg2+–thymine
研究领域:
分子生物学
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环境科学
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纳米技术
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DOI
高影响因子
Analytical Methods
·
2021
·Vol. 14
·期 3
·278-285
·
IF 2.896
Ting Zhou,Meijuan Li,Na Li,Yulin Dong,Dan Liu,Xiaosong Hu,Zhizhong Xie,Deyu Qu,Xi Li,Chaocan Zhang
An ultrasensitive and specific-selection electrochemical sensor was constructed for Hg2+ detection based on Au nanoparticles and molybdenum selenide (Au NPs@MoSe2) as well as the thymine–Hg2+–thymine (T–Hg2+–T) coordination. Herein, Au NPs@MoSe2 not only could improve the sensitivity due to the large surface area and good electrical conductivity but also offered more sites to immobilize thiol-labeled T-rich hairpin DNA probes (P-1), which has a specific recognition for Hg2+ and methylene blue-labeled T-rich DNA probes (MB-P). When Hg2+ and MB-P exist, P-1 and MB-P can form a stable T–Hg2+–T complex. Then, methylene blue can be close to the electrode and detectable via differential pulse voltammetry (DPV). Benefiting from the specific recognition of T–Hg2+–T and the merits of Au NPs and MoSe2, the fabricated biosensor presented an ultrasensitive and highly selective performance. The DPV responses had a positive linear relationship with Hg2+ concentrations over ten orders of magnitude from 1.0 × 10−16 to 1.0 × 10−7 mol L−1. The detection limit was down to 1.1 × 10−17 mol L−1. Moreover, the developed sensor exhibited a promising application for trace Hg2+determination in water samples.
研究领域:
分析化学
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环境科学
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纳米技术
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电化学
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DOI
PubMed
高影响因子
Journal of the Taiwan Institute of Chemical Engineers
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2017
·
IF 4.217
Hao Luo,Shengxiao Zhang,Xiaoyan Li,Xia Liu,Qiang Xu,Junshen Liu,Zhenhua Wang
Tannic acid (TA) film covered magnetic microspheres (Fe 3 O 4 @TA–Fe 3+ ) was synthesized and applied for removal of Pb 2+ and Hg 2+ from aqueous solution. The resulted Fe 3 O 4 @TA–Fe 3+ was characterized with thermo-gravimetric analysis, vibrating sample magnetometer, transmission electron microscope, and Fourier transform infrared spectra. The adsorption of pollutants was pH dependent because the complexation of TA with Fe 3+ was disassembled at low pH. The composites showed high maximum adsorption capacity for Pb 2+ up to 1115.3 mg/g and Hg 2+ to 279.4 mg/g. Furthermore, the Fe 3 O 4 @TA–Fe 3+ composites could be easily separated from the solution by a magnet after adsorption because of the excellent superparamagnetic property. Thermodynamics study indicated that the adsorption of Pb 2+ and Hg 2+ on Fe 3 O 4 @TA–Fe 3+ sorbents was spontaneous, chaotic degree decreasing and endothermic process. The present results warrant the promising application of magnetic Fe 3 O 4 @TA–Fe 3+ composites for removal of Pb 2+ and Hg 2+ from contaminated water, and this study is the first application of TA film in environmental remediation.
研究领域:
环境科学
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材料科学
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产品关联
DOI
高影响因子
CHEMICAL PHYSICS LETTERS
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2025
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IF 3.1
Yingying Kou,Zhuang Wu,Chenling Yan,Jinggang Wang,Fan Liu,Donghai Yuan
Development of a new sensor for the simple detection of Hg 2+ , which improves on the shortcomings of conventional mercury detection.The size of the nanogold(AuNPs) particles was controlled by controlling the amount of sodium citrate and gold salt. AuNPs was also functionalized by arginine and melamine. The functionalized nanogold was sensitive and selective for Hg 2+ . It is also useful in real water samples. The 32 nm nanogold modification had the lowest limit of detection (LOD). The melamine-functionalized 32 nm AuNPs had a LOD of 4.17 μmol/L, which was better than the arginine-functionalized 32 nm AuNPs with a LOD of 5 μmol/L.
研究领域:
分析化学
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环境科学
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产品关联
DOI
高影响因子
JOURNAL OF HETEROCYCLIC CHEMISTRY
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2024
·
IF 2
Ling Li,Yinuo Yao,Xiaowan Wang,Yaoqi Yu,Tailong Ji,Han Li,Yi Li,Yuanyuan Liu
A highly selective fluorescent sensor Por-RBO for determination of Hg 2+ was designed and synthesized with Rhodamine B and Tetraphenylporphyrin. The sensor can determine the Hg 2+ of a solution within the pH 5.0–8.0, free from interference of other metal ions. When detected in buffer solution, the fluorescence was the strongest when five times the concentration of Hg 2+ ion was added. Calculated by fluorescence titration method, the detection limit of sensor Por-RBO for Hg 2+ ion was as low as 0.12 μmol/L. The geometries of Por-RBO and Por-RBO -Hg 2+ were optimized at the B3LYP/6-31G** level by density functional theory. The charge distribution, orbital interactions, and bonding characteristics were analyzed and compared in detail to discuss the recognition mechanism and structure–fluorescence property relationships. The results of cell fluorescence imaging and CCK-8 experiments indicate that the sensor Por-RBO exhibits lower cytotoxicity. Por-RBO can be used for fluorescence distribution imaging of Hg 2+ in living cells.
研究领域:
分析化学
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生物医学工程
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环境科学
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DOI
高影响因子
MATERIALS CHEMISTRY AND PHYSICS
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2022
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IF 4.778
Jiao He,Congwei Li,Xinjian Cheng
Three chitosan-BODIPY probes were prepared in this work. The water solubility of original chitosan has been improved. Water soluble fluorescent probes were obtained. They also exhibited good sensing ability to Hg 2+ /Hg + ions. Firstly, through the amidation reaction, arginine, cysteine, and tryptophan were grafted respectively onto chitosan chains. And then chitosan-BODIPY probes were produced by means of Schiff base formation reaction. By this way, the high structural regularity of chitosan polymer chains was changed with introducing amino acids and fluorescent groups. It also endowed fluorescence sensing ability. They could recognize Hg 2+ /Hg + ions with the interaction of C N groups. It could selectively recognize Hg 2+ /Hg + in aqueous solution, the detection limits reached 0.747μM/0.783 μM. Moreover, by the introduction of hydrophilic groups, the contact angle of modified chitosan film was improved as well. It realized performance transformation from the hydrophobic to hydrophilic. The viscoelasticity , thermal, rheological properties and fluorescence properties of the hydrogels were investigated. C N groups not only acted as a binding site to coordinate with heavy metals, but also could enhance the water solubility of the fluorescent chitosan.
研究领域:
生物化学
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材料科学
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环境科学
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DOI
高影响因子
MOLECULES
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2023
·Vol. 29
·期 1
·1
·
IF 4.6
Chunyuan Tian,Feiyan Tang,Wei Guo,Minggang Wei,Li Wang,Xuming Zhuang,Feng Luan
The excessive concentration of heavy-metal mercury ions (Hg2+) in the environment seriously affects the ecological environment and even threatens human health. Therefore, it is necessary to develop rapid and low-cost determination methods to achieve trace detection of Hg2+. In this paper, an Electrochemiluminescence (ECL) sensing platform using a functionalized rare-earth material (cerium oxide, CeO2) as the luminescent unit and an aptamer as a capture unit was designed and constructed. Using the specific asymmetric matching between Hg2+and thymine (T) base pairs in the deoxyribonucleic acid (DNA) single strand, the “T−Hg−T” structure was formed to change the ECL signal, leading to a direct and sensitive response to Hg2+. The results show a good linear relationship between the concentration and the response signal within the range of 10 pM–100 µM for Hg2+, with a detection limit as low as 0.35 pM. In addition, the ECL probe exhibits a stable ECL performance and excellent specificity for identifying target Hg2+. It was then successfully used for spiked recovery tests of actual samples in the environment. The analytical method solves the problem of poor Hg2+recognition specificity, provides a new idea for the efficient and low-cost detection of heavy-metal pollutant Hg2+in the environment, and broadens the prospects for the development and application of rare-earth materials.Keywords:CeO2;electrochemiluminescence;mercury ions;aptamer;environment
研究领域:
分析化学
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环境科学
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DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
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2024
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IF 8.1
Xiaoxia Ye,Zhihong Zheng,Jinwei Zhu,Jie Chen,Jianfei Zhou,Bi Shi
Adsorptive removal of mercury ion from wastewater has become a hot topic due to the toxicity and persistence; acquiring adsorbent materials with high-capacity, rapid-kinetic, super-selective while low-cost features are highly demanded. Herein, based on the full functionality of collagen fiber (CF) from the leather waste, we proposed an innovative synthetic approach through exploiting amino-functionalized ZIF-7 (ZIF-7-NH 2 ) as functional groups to facilely in-situ incorporate with CF, affording low-cost but effective adsorbent materials of CF/ZIF-7-NH 2 composite maximizing both functions of CF and ZIF-7-NH 2 in the Hg(II) capture. Remarkably, it exhibits an ultra-high capacity as high as 909.09 mg g - 1 , fast kinetics that could remove 99.01 % of 200 mg·L -1 within 20 min, and significant selectivity of S Hg/M ( K d Hg / K d M ) as large as 522–1017 over Mg 2+ , K + , Ca 2+ , Cd 2+ , and Mn 2+ . We understand such an impressive adsorption is contributed by the synergistic action between functional groups including on the CF and ZIF-7-NH 2 . This study offers an effective method for removing heavy metal ions, achieving efficient removal of Hg(II) ions for pollution control, and promoting the reuse of waste CF to reduce waste accumulation in various aspects.
研究领域:
环境科学
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材料科学
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生物学
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产品关联
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2024
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IF 4.3
Brian Musikavanhu,Tingting Pan,Quanhong Ma,Yongdi Liang,Zhaoli Xue,Lei Feng,Long Zhao
Fluorescent chemosensors are often preferred for tracking toxic ions because of their non-destructive measurement and ease of use in environmental real samples and biosystems. Exploring high selectivity, great sensitivity, and biocompatible fluorophores with facile, accessible and dual-responsive features is currently highly demanding. A coumarin-based naphthol hydrazone Schiff base chemosensor, NaChro , is designed and synthesized in a two-step process to detect toxic metal ions with strong emission. Fluorescence spectra analysis demonstrates that the probe binds to Hg 2+ and Pb 2+ ions with a 1:1 and a 2:1 stoichiometry, respectively, with high sensitivity, short response time and minimal interference from other metal ions. The observed reversible turn-on reaction was attributed to the inhibition of C = N isomerization and excited-state intramolecular proton transfer (ESIPT) processes once the ions were introduced. The practical applications of NaChro are successfully addressed in paper strips, various water samples, HeLa cells and Zebrafish, demonstrating that the probe can detect and track Hg 2+ and Pb 2+ ions in environmental samples and biosystems.
研究领域:
环境科学
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生物化学
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分析化学
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产品关联
DOI
PubMed
高影响因子
Journal of Environmental Sciences
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2024
·
IF 5.9
Yongli Liu,Xiaoyan Su,Huanjia Liu,Guifen Zhu,Guobei Ge,Yuxin Wang,Penghui Zhou,Qingxiang Zhou
In present work, blue carbon dots (b-CDs) were derived from ammonium citrate and guanidine hydrochloride, and red carbon dots (r-CDs) were stemmed from malonate, ethylenediamine and meso‑tetra (4-carboxyphenyl) porphin based on facile hydrothermal method . Eco-friendly ratiometric fluorescence probe was innovatively constructed to effectively measure Hg 2+ utilizing b-CDs and r-CDs. The developed probe displayed two typical emission peaks at 450 nm from b-CDs and 650 nm from r-CDs under the excitation at 360 nm. Mercury ion has strong quenching effect on the fluorescence intensity at 450 nm due to the electron transfer process and the fluorescence change at 450 nm was used as the response signal, whereas the fluorescence intensity at 650 nm kept unchangeable which resulted from the chemical inertness between Hg 2+ and r-CDs, serving as the reference signal in the sensing system. Under optimal circumstances, this probe exhibited an excellent linearity between the fluorescence response values of ΔF 450 /F 650 and Hg 2+ concentrations over range of 0.01–10 µmol/L, and the limit of detection was down to 5.3 nmol/L. Furthermore, this probe was successfully employed for sensing Hg 2+ in practical environmental water samples with satisfied recoveries of 98.5%–105.0%. The constructed ratiometric fluorescent probe provided a rapid, environmental-friendly, reliable, and efficient platform for measuring trace Hg 2+ in environmental field.
研究领域:
分析化学
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环境科学
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产品关联
DOI
PubMed
高影响因子
ANALYTICAL SCIENCES
·
2024
·Vol. 40
·期 6
·1023-1030
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IF 1.8
Zhang Yuecheng,Sun Lingbo,Li Chengjia,Ma Jing,Zhang Shiyu,Wang QingQing,Ma Hongyan
Dopamine (DA) is a neuromodulatory molecule that plays critical roles in many biological processes. The dysfunctions of the DA system are closely associated with several nervous system diseases. Therefore, it is urgent to establish a simple and accurate method for DA analysis. In this study, an economic and accurate DA ratiometric sensor was established using dual-emission carbon dots (DE-CDs). DE-CDs were first synthesized by the one-step solvothermal method and two separate fluorescence emission peaks at 340 and 500 nm were observed under the excitation of 310 nm. In the presence of Hg 2+ , the fluorescence signal at 340 nm was significantly quenched, while the signal at 500 nm keeps stable. Upon adding DA, the quenched signal at 340 nm was significantly recovered, whereas the signal at 500 nm remains stable. Therefore, a novel ratiometric sensor for DA analysis was established. This method shows a good linear range from 500 nM to 100 μM, and the detection limit was calculated to be 80 nM. Moreover, this established method shows excellent specificity and could be applied in real sample analysis, showing great potential for application in clinical research. Graphical abstract
研究领域:
分析化学
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生物医学
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DOI
PubMed
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2019
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IF 3.571
Tang Gao,Xueyan Huang,Shuai Huang,Jie Dong,Kai Yuan,Xueping Feng,Tingting Liu,Kunqian Yu,Wenbin Zeng
Using Hg2+-induced umpolung reaction and aggregation induced emission (AIE), we have rationally developed a water-soluble fluorescent probe 2,2′-(((4-(4,5-bis(4-methoxyphenyl)-1-phenyl-1H-imidazol-2-yl)phenyl)methylene)bis(sulfanediyl))diethanol (MPIPBS) for Hg2+ detection. MPIPBS was found to have high selectivity and sensitivity toward Hg2+ detection. The mechanism of MPIPBS response to Hg2+ was verified by 1H NMR titration, HPLC, and HRMS spectroscopy. The detection limit was examined to be 1.45 nM, which is lower than most reported probes for Hg2+. Taking advantage of excellent optical properties of AIEgen, a paper based sensor for Hg2+ detection was fabricated by immobilizing the MPIPBS on Waterman test paper. Meanwhile, MPIPBS showed satisfactory analytical performance in real water and urine samples. Further, thanks to the high water solubility, cell membrane permeability and low cytotoxicity, MPIPBS was further used to detect Hg2+ both in living cells and zebrafish. We anticipate that the prepared probe was available to detect Hg2+ in environment and biosamples.
研究领域:
分析化学
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生物医学
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环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）