Droplet
·
2024
·Vol. 3
·期 2
·e118
·
IF 0
Chuchen Yue,Qingwen Dai,Xiaolong Yang,Carsten Gachot,Wei Huang,Xiaolei Wang
Preventing the accretion of droplets on surfaces is vital and slippery liquid-infused porous surfaces (SLIPS) have promising application prospects, such as surface self-cleaning and droplet transportation. In this work, controllable self-transport of bouncing droplets on ultraslippery surfaces with wedge-shaped grooves is reported. The impact behaviors of droplets on SLIPS under various impact velocities and diameters are explored, which can be classified as hover, total bounce, partial bounce, Worthington jet, and crush. SLIPS with wedge-shaped grooves were designed to transport accreted droplets. An energy and transport model is established to explain the impact and self-transport mechanism, where the Laplace pressure and moving resistance between droplets play a key role. Finally, SLIPS with branched wedge-shaped grooves were designed for droplet self-transport and demonstrated advantages. This work provides a general reference for spontaneous motion control of sessile droplets, droplets with initial impacting velocity, or even liquid films.
研究领域:
表面工程
·
流体力学
·
材料科学
✓ 已验证
DOI
MATERIALS & DESIGN
·
2025
·
IF 7.9
Yu Ma,Bin Zhao,Guozhen Yan,Ting Zhou,Zhihua Xu,Zhihan Niu,Zhenghong Xu,Tongtong Zhang,Feng Shi
Nucleic acid dyes play important roles in the quantification and detection of nucleic acids by binding to nucleic acids. However, traditional nucleic acid dyes pose great environmental and economic challenges due to their high price, high toxicity, long dyeing time, low sensitivity and insufficient stability. To overcome these problems, we developed a new nucleic acid dye based on carbon dots, which were generated through hydrothermal synthesis with liquorice components as precursors and a system containing ethylenediamine. This new type of carbon dot can effectively replace traditional dyes and can be used to efficiently visualize DNA, RNA and plasmids via agarose gel electrophoresis. Then, we studied the interaction mechanism between carbon dots and nucleic acids by UV–visible spectroscopy, Fourier transform infrared spectroscopy and circular dichroism spectroscopy. The interaction between the carbon dots and nucleic acids mainly occurred through groove binding and was accompanied by a slight electrostatic interaction. Carbon dots-based nucleic acid dyes, with their low cost, simple synthesis process and high stability, have opened a new path for the field of nucleic acid detection. Its research and development not only promote the frontier progress of biological science and medicine but also introduces innovative strategies and tools for scientific research and clinical practice.
研究领域:
生物化学
·
分子生物学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
·
2015
·
IF 2.96
Yan-Qing Wang,Hong-Mei Zhang
Bisphenol A and its analogues have carcinogenic potentials and toxicities. However, there are lacks of studies elucidating gene toxic interactions of bisphenols with DNA. In this work, the binding modes of five bisphenol compounds with calf thymus DNA were characterized. The multi-spectroscopic experimental results indicated that the fluorescence quenching of bisphenols by calf thymus DNA point to groove binding. The ultraviolet visible and circular dichroism spectral data displayed that bisphenols partly induced conformational changes of calf thymus DNA. In addition, the binding constants of bisphenol A, diphenolic acid, bisphenol AF, bisphenol AP, bisphenol fluorine with calf thymus DNA obtained from fluorescence emission spectra were 1.09 × 10 4 , 3.65 × 10 4 , 4.46 × 10 4 , 1.69 × 10 4 , 4.49 × 10 4 L mol −1 at 298.15 K, which indicated that the multi-noncovalent binding forces were involved in the binding processes. In silico investigations indicated that DNA has the preferable binding sites binding with bisphenols by minor groove binding and electrons transfer from DNA bases to bisphenols occurred. In addition, the structural differences of these five bisphenols partly affected the binding ability of them with DNA.
研究领域:
生物化学
·
毒理学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Materials Chemistry A
·
2024
·
IF 10.7
Huanlin Lyu,Suihan Cui,Chao Huang,Qingdong Ruan,Xiaolin Zhang,Junmin Xu,Fangyu Xiong,Dan Li,Paul K. Chu
Aqueous zinc-ion batteries (ZIBs) are desirable energy storage devices because of their low cost, safety, abundant Zn reserve, and environmental friendliness. However, Zn dendrite growth remains the main reason limiting the life span of ZIBs. Herein, a quick, simple, and scalable hydrochloric acid (HCl) treatment is designed to suppress the formation of Zn dendrites on Zn metal anodes. Scanning electron microscopy and atomic force microscopy reveal that the initial surface structure of the Zn metal anode determines the subsequent plating/stripping behavior. By soaking the Zn foil in HCl for 5 s (HCl-5 Zn), microgrooves are formed on the surface, but longer immersion destroys the special structure. This special microgroove structure homogenizes the electric field on the surface of the Zn plate, giving rise to more uniform Zn deposition. Compared to the pristine and over-processed Zn electrodes, HCl-5 Zn shows less Zn nucleation and smaller plating overpotentials resulting in suppression of Zn dendrites. Furthermore, HCl-5 Zn tends to deposit on the (002) plane of Zn to improve the cycling stability of the cell compared to the (001) plane of Zn. The symmetrical cell composed of the HCl-5 Zn anode exhibits small voltage hysteresis and excellent cycling stability. The cycling characteristics and low voltage polarization are improved, as demonstrated by the assembled symmetrical and full batteries comprising the K0.5V2O5@CC cathode. Moreover, the strategy is suitable for flexible batteries with hydrogel as the electrolyte. The results reveal a simple strategy to minimize dendrite formation and provide insights into the commercial development of ZIBs.
研究领域:
材料科学
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MOLECULAR LIQUIDS
·
2021
·
IF 6.165
Dan Zhang,Junhui Pan,Deming Gong,Guowen Zhang
Indole-3-butyric acid (IBA) is a broad-spectrum efficient plant growth regulator. It has been widely used in crop production, but may have a potential security risk due to its residual accumulation in agricultural products. Herein, the binding mode between IBA and calf thymus DNA (ctDNA) and influence of IBA on the structure of ctDNA were explored by using spectroscopic methods, viscosity measurement, melting temperature studies coupled with computational approaches. Fluorescence titration results indicated that ctDNA induced IBA fluorescence quenching in a static manner. The measured thermodynamic parameters demonstrated that the structure of IBA-ctDNA complex was primarily stabilized by hydrogen bonds and van der Waals forces. Fluorescence experiments, viscosity analyses and circular dichroism (CD) measurements confirmed that IBA interacted with ctDNA in terms of groove mode with no significant conformational change of ctDNA. Furthermore, molecular docking showed that IBA was preferentially bound to the minor groove of ctDNA rich in A-T bases. Molecular dynamics simulation further revealed IBA and DNA forming a stable complex and IBA could slightly increase the flexibility of ctDNA base pairs. In addition, IBA did not cause significant damage to the structure of DNA. These findings may supply conducive insights into the toxicity mechanisms of IBA at the molecular level.
研究领域:
生物化学
·
分子生物学
·
毒理学
✓ 已验证
DOI
高影响因子
LUMINESCENCE
·
2020
·Vol. 36
·期 1
·35-44
·
IF 1.855
Hui Guo,Jiawen Xie,Tancong Liao,Xun Tuo
Donepezil (DNP) is one of approved drugs to treat Alzheimer's disease (AD). However, the potential effect of DNP on DNA is still unclear. Therefore, the interaction of DNP with calf thymus DNA (DNA) was studied in vitro using spectroscopic and molecular docking methods. Steady-state and transient fluorescence experiments showed that there was a clear binding interaction between DNP and DNA, resulting from DNP fluorescence being quenched using DNA. DNP and DNA have one binding site between them, and the binding constant (K b ) was 0.78 × 10 4 L·mol −1 at 298 K. In this binding process, hydrophobic force was the main interaction force, because enthalpy change (ΔH) and entropy change (ΔS) of DNP–DNA were 67.92 kJ·mol −1 and 302.96 J·mol −1 ·K −1 , respectively. DNP bound to DNA in a groove-binding mode, which was verified using a competition displacement study and other typical spectroscopic methods. Fourier transform infrared (FTIR) spectrum results showed that DNP interacted with guanine (G) and cytosine (C) bases of DNA. The molecular docking results further supported the results of spectroscopic experiments, and suggested that both Pi-Sigma force and Pi-Alkyl force were the major hydrophobic force functioning between DNP and DNA.
研究领域:
生物化学
·
药物研究
·
分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Chenbo Yuan,Liwen Yin,Peng Du,Yu Yu,Kaifu Zhang,Xiaodi Ren,Xiaowen Zhan,Shan Gao
The application of zinc (Zn) metal in aqueous Zn metal batteries (ZMBs) has been hindered by the susceptibility of Zn anodes to dendritic electrodeposition due to its inhomogeneous surface structures. Herein, we design uniform microgroove patterns on practically accessible Zn foil anodes using a simple and scalable acid etching strategy. The unique surface structure guides homogeneous Zn deposition, accelerates interfacial reaction kinetics, and inhibits electrolyte corrosion. The resulting Zn anodes afford an excellent plating/stripping stability of 2920 h at an ultralow overpotential of 19.5 mV under 1 mA cm −2 /1 mAh cm −2 cycling, with both the cycle life and overpotential ranking among the best records reported thus far. Moreover, the synergetic mechanisms for morphology-induced enhancement were rigorously elucidated. The present strategy contributes a reliable performance baseline for future studies, and can be readily combined with other emerging tactics such as surface coating to accelerate further performance upgrades towards practical ZMBs.
研究领域:
材料科学
·
电化学
·
能源存储
✓ 已验证
产品关联
DOI
高影响因子
Scientific Reports
·
2021
·Vol. 11
·期 1
·1-8
·
IF 4.38
Chang Chao,Han Zhaoyang,He Xiaoyu,Wang Zongyu,Ji Yulong
As the electronic technology becomes increasingly integrated and miniaturized, thermal management has become a major challenge for electronic device applications. A heat pipe is a highly efficient two-phase heat transfer device. Due to its simple structure, high thermal conductivity and good temperature uniformity, it has been used in many different industrial fields. A novel aluminum flat heat pipe, with micro-grooves, has in the present work been designed and fabricated by using a 3D printing technology. Aluminum powder was used as a raw material, which was selectively melted and solidified to form the shape of the heat pipe. The sintered aluminum powder increased the roughness of the inner surface of the heat pipe, and the designed micro-grooves further enhanced the capillary forces induced by the wick structure. The wettability, for the working fluid (acetone), was excellent and the capillary forces were sufficient for the working fluid to flow back in the pipe. The effects of working fluid filling ratio, on the heat transfer performance of the heat pipe, was also investigated. It was shown that a filling ratio of 10% gave the best heat transfer performance with the lowest thermal resistance. The 3D-printed flat heat pipe was, therefore, also tested for the thermal management of a LED. The temperature of the LED could be kept within 40 °C and its service life became prolonged.
研究领域:
电子工程
·
材料科学
·
热能工程
✓ 已验证
DOI
高影响因子
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
·
2024
·
IF 3.1
Lin Yuan,Qiuyun Wang,Hailong Yu,Peng Lang,Han Li,Xun Gao,Jingquan Lin
The highly sensitive detection of heavy metal elements in aqueous solution has been achieved by the combination of circular grooves and nanoparticle-enhanced laser-induced breakdown spectroscopy. The effects of Ag nanoparticles (Ag NPs) and circular grooves on the spectral emission of Cu, Pb and Cr have been investigated. The results show that both Ag NPs and circular grooves can enhance the spectral emission of heavy metal elements, and the circular grooves can improve the spectral reproducibility. The prepared micro/nanostructures can suppress the coffee ring effect and improve the absorption efficiency of light. The average relative standard deviation of the spectral emission can be diminished. By establishing calibration curves for Cu, Pb, and Cr elements, the limits of detection (LODs) for Cu, Pb and Cr elements have been obtained. The results show that by employing Ag NPs and circular grooves the lowest LOD of 0.10 μg mL−1 can be achieved. This improved spectral performance (spectral intensity, stability and detection sensitivity) originates mainly from the collective oscillation of free electrons of Ag NPs excited by the incident laser pulse, which confines the electromagnetic energy with a strongly enhanced electric field. The enhancement in electric field intensity of Ag NPs is calculated and the seed electron is proved to be predominantly excited through a multiphoton photoemission process under the experimental conditions. The results provide an efficient pathway for improving the detection sensitivity of heavy metals in aqueous solution.
研究领域:
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Mingzhao Guo,Shaoqing Bai,Yujun Wang,Guangsheng Luo
A novel micronozzle array with grooves was specially designed for high-throughput microdroplet generation and high-efficiency mixing of heterogeneous systems without surfactants. The microgrooves, with a width of 25 μm between micropores, could significantly prevent the dispersed phase from spreading on the membrane surface and reduce the microdroplet size and polydispersity at sufficiently high fluxes of the dispersed phase. Through different oil–water systems, the effects of flow conditions, system physical properties, and flow patterns on droplet size were investigated in the micronozzle array device. Under the jetting flow pattern, the n-hexane, dichloromethane , and ethyl acetate droplets could obtain average diameters of 35 μm, 31 μm, and 24 μm, respectively, and the coefficient of variation was between 20% and 40%. The dripping and jetting flow regions were demarcated to fully understand the transition of the flow pattern. Furthermore, a droplet size prediction model was established based on force equilibrium. The micronozzle array proposed in this work has great potential for future practical applications.
研究领域:
微流控技术
·
化学工程
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2014
·
IF 2.129
Jinhua Zhu,Lanlan Chen,Yingying Dong,Jiazhong Li,Xiuhua Liu
In this work, the interaction of 5-Hydroxymethyl-2-furfural (5-HMF) with calf thymus DNA (ctDNA) under simulated physiological conditions (Tris–HCl buffer of pH 7.40), was explored by UV absorption spectroscopy, fluorescence spectroscopy and molecular modeling method, using ethidium bromide (EB) as a fluorescence probe of DNA. The fluorescence quenching mechanism of EB–ctDNA by 5-HMF was confirmed to be a static quenching, which derived from the formation of a new complex. The binding constants of 5-HMF with DNA in the presence of EB were calculated to be 2.17 × 10 3 , 4.24 × 10 3 and 6.95 × 10 3 L mol −1 at 300, 305 and 310 K, respectively. The calculated thermodynamic parameters, enthalpy change Δ H and entropy change Δ S , suggested that both hydrophobic interactions and hydrogen bonds played a predominant role in the binding of 5-HMF to DNA. According to the UV absorption spectroscopy and melting temperature ( T m ) curve results, the binding mode of 5-HMF with DNA was indicative of a non-intercalative binding, which was supposed to be a groove binding. The molecular modeling results showed that 5-HMF could bind into the hydrophobic region of ctDNA and supported the conclusions obtained from the above experiments.
研究领域:
生物化学
·
分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
·
2018
·
IF 3.974
Jiao Yang Lu,Qiu Yan Zhu,Xin Xing Zhang,Fu Rui Zhang,Wei Tao Huang,Xue Zhi Ding,Li Qiu Xia,Hong Qun Luo,Nian Bing Li
Due to rapid change in information technology, many consumer electronics become electronic waste which is the fastest-growing pollution problems worldwide. In fact, many discarded electronics with prefabricated micro/nanostructures may provide a good basis to fulfill special needs of other fields, such as tissue engineering, biosensors , and energy. Herein, to take waste optical discs as an example, we demonstrate that discarded electronics can be directly repurposed as highly anisotropic platforms for in vitro investigation of cell behaviors, such as cell adhesion, cell alignment, and cell-cell interactions. The PC12 cells cultured on biocompatible DVD polycarbonate layers with flat and grooved morphology show a distinct cell morphology, indicating the topographical cue of nanogrooves plays a key role in guidance of neurites growth. By further monitoring cell morphology and alignment of PC12 cells cultured on the DVD nanogrooves at different differentiation times, we find that cell contact interaction with nanotopographies is dynamically adjustable with differentiation time from initial disorder to final order. This study adds a new dimension to not only solving the problems of supply of materials and fabrication of nanopatterns in neural tissue engineering, but may also offering a new promising way of waste minimization or reuse for environmental protection.
研究领域:
生物医学工程
·
组织工程
·
环境科学
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）