MACROMOLECULAR RAPID COMMUNICATIONS
·
2015
·Vol. 36
·期 15
·1402-1408
·
IF 4.941
Rui Qi,Yong Jin,Xinfeng Cheng,Baozhu Fan,Tongbing Sun,Shaojun Peng,Hanping Li
A novel rod-containing block copolymer is constructed by supramacromolecular self-assembly of α-cyclodextrin and a triblock copolymer with methoxy polyethylene glycol as the flanking chains and the midterm block alternately connected by 2,2-dimethylolbutyric acid and isophorone diisocyanate. The assembled rod-containing block copolymer shows an exciting phenomenon of concentration- and pH-dependent morphological switching of well-defined nanostructures. In the solutions at pH 9.2, spherical micelles, rod-like micelles, and hydrogel are observed successively with an increase of the concentration. Notably, the rod-like micelles are composed of spherical segments due to the combination of the crystalline cores of the spherical micelles. In addition, 1D nanostructures with different curvatures from linear rod-like micelles (pH 9.2) to ring-shaped micelles (pH 7.5) can be obtained by controlling the pH values of the assembled systems.
研究领域:
高分子化学
·
材料科学
·
超分子化学
✓ 已验证
DOI
高影响因子
Advanced Sensor and Energy Materials
·
2022
·
IF 0
Wen-Xuan Fu,Ping Zhou,Wei-Liang Guo,Bin Su
As one of most advanced transduction techniques, electrochemiluminescence (ECL), such as that generated by tris(2,2′-bipyridyl)ruthenium (Ru(bpy) 3 2+ ), has been extensively used in chemical sensing and analysis, but the reaction mechanism has not been fully resolved. Aiming at gaining insightful mechanistic information on the coreactant system involving (Ru(bpy) 3 2+ ) and tri- n -propylamine (TPrA), herein we investigate the variation of thickness of ECL layer (TEL) with the concentration ratio of (Ru(bpy) 3 2+ ) to TPrA ( c Ru / c TPrA ) by ECL microscopy. Using carbon fiber as the working electrode, TEL was observed to grow with the increase of c Ru / c TPrA remarkably. In conjunction with finite element simulations, the extension of ECL layer was rationalized to be associated with the incremental contribution of so-called “catalytic route”. This route offers an additional channel of generating remote light emission in solution, apart from surface-confined emission produced by the “oxidative-reduction route”. Given the quantitative analysis of coreactant-type analytes is often based on the calibration curve, namely a graph generated by plotting the measured light intensity of a series of standard solutions against their concentrations, the contribution of “catalytic route” particularly at a low concentration of analyte (equivalent to a relatively large c Ru / c TPrA ) is favorable to the analytical sensitivity. Moreover, the presence and absence of this route will result in a nonlinear and linear calibration curve, respectively, for example in the detection of TPrA and pyruvate. The results highlight the microwire-based imaging approach can provide insightful mechanistic information and help unveil the concentration dependence of measured ECL intensity for precise quantitative analysis.
研究领域:
分析化学
·
电化学
·
生物传感
✓ 已验证
DOI
Frontiers of Environmental Science & Engineering
·
2025
·Vol. 19
·期 12
·1-11
·
IF 6.4
Zhu Ziyue,Zhan Yuehao,Hur Kyu,Dong Shengkun
Pesticides and DBPs coexist in tap waters at trace levels, demanding attention for long term health protection. To allocate resource for water contaminant control, regulated chemicals need to be prioritized. The current prioritization is primarily based on the toxicity additivity assumption that ranks toxicity-weighted concentration of chemicals. However, recent findings revealed that the nonadditive synergistic and antagonistic toxicological interactions are also prevalent in waters, potentially biasing previous prioritization rankings. To demonstrate a possible framework for improved prioritization, we identified the cytotoxic interactions, component contributions, and forcing compounds among six common toxic pesticides and DBPs based on the Chou-Talalay approach. In the “Malathion + DBPs” combination, the interaction type shifted from additivity to antagonism as the concentration increased, indicating concentration dependency. In the “Chlorothalonil + DBPs” combination, the strong antagonism led to a convergence of cytotoxicity value among the three mixtures. A comparison of cytotoxicity of “Deltamethrin + IAN/BAN” revealed that the interaction type affected the mixture-induced cytotoxicity. To unravel the cytotoxic interactions and forcing chemicals at both environmentally-relevant and bioaccumulation-attainable concentrations, we analyzed the componential contributions among “pesticides + DBPs” mixtures at LC 0.1 and LC 50 levels and identified the forcing cytotoxic compounds in each. At LC 0.1 , pesticides need to be prioritized in only two combinations out of nine; at LC 50 , DBPs should be prioritized only in “Chlorothalonil + DBPs” combinations. These results provide a framework for the prioritization among “pesticides + DBPs” in water and possibly other classes of contaminants.
研究领域:
环境毒理学
·
水处理化学
·
公共卫生
·
环境健康
·
分子毒理学
·
风险评估
·
污染物控制
✓ 已验证
DOI
高影响因子
Nanoscale Research Letters
·
2018
·Vol. 13
·期 1
·1-10
·
IF 3.125
Cao Hongyan,Guo Fenghao,Chen Zhiyong,Kong Xiang Zheng
Stimuli-responsive polymers have received growing attention in recent years owing to their wide applications in diverse fields. A novel stimuli-responsive polymer, based on oligo(ethylene glycol) diacrylate (OEGDA) and methacrylic acid (MAA), P(OEGDA-MAA), is prepared by precipitation polymerization and is shown to have a LCST-type VPTT (volume phase transition temperature) at 33 °C in water and a UCST-type VPTT at 43 °C in ethanol, all at concentration of 1 mg/mL. Both VPTTs are strongly concentration and pH dependent, providing an easy way to tune the phase transition temperature. The polymer is characterized with regard to its composition and its morphology in water and in ethanol at different concentration. The two transitions are studied and interpreted based on the results. This work provides a novel way for the preparation of a new type of stimuli-responsive polymer with great potential for different applications, particularly those in biomedical areas because PEG-based stimuli-responsive polymers are known to be nontoxic and non-immunogenic.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）