The widespread adoption of polyurethane (PU) materials in adhesives and ultraviolet (UV)-resistant applications is limited by the challenge of balancing stretchability, recyclability, and self-healing capabilities, which requires an advanced molecular structural design. Here, we synthesize a castor-oil-based PU (COPUSD) that integrates disulfide bonds and multiple hydrogen bonds, drawing inspiration from the remarkable self-healing capabilities and stretchability of sea cucumbers. This biomimetic approach facilitates the development of a multifunctional PU material with excellent self-healing properties, tunable stretchability, and recyclable processing characteristics. The resulting PUs are employed as adhesion and anti-UV radiation materials and exhibit excellent adhesion properties. The transmittance of the PU is close to 0% in the range of 200–400 nm, indicating a strong blocking ability against UV. This study presents a pioneering approach for developing versatile and scalable PU materials that combine adjustable self-healing capabilities and efficient recyclability for adhesive and UV-resistant applications.
The symptomatic management of hemorrhagic shock complicated by open fractures is a great challenge, because it is also complicated by complex wound bleeding, bacterial infection, and bone defects. Inspired by the water absorption and cross-sectional microstructure of sea cucumbers, in this study, a new sea cucumber-like aerogel (GCG) is proposed. Its aligned porous structure and composition can stop bleeding rapidly and effectively with a blood clotting index of 3.73 ± 1.8%. More importantly, the data of in vivo hemostasis test in an amputating rat tail hemostatic model (15.69 ± 2.45 s, 26.95 ± 8.43 mg) and liver puncture bleeding model (23.77 ± 2.68 s, 36.22 ± 16.92 mg) also indicate the excellent hemostatic performance of GCG. In addition, GCG also shows a significant inhibitory effect on S. aureus and E. coli , which can prevent the occurrence of postoperative osteomyelitis. Not only that, after filling in the bone defect, it is shown that this GCG aerogel completely degrades eight weeks after surgery and induces new bone ingrowth, achieving functional regeneration after hemostasis of an open fracture defect. Generally, because of its combination of hemostatic, antibacterial, and osteogenic activities, this new aerogel is a promising option for open fractures treatment.
危险品化学品经营许可证（带存储）