LUMINESCENCE
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2015
·Vol. 30
·期 8
·1269-1273
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IF 1.518
Yinggui Zhu,Lili Zou,Qin Dong,Derong Jiang
Quenching effects of bergenin, based on the electrochemiluminescence (ECL) of the tris(2,2′-bipyridyl)-ruthenium(II) (Ru(bpy) 3 2+ )/tri-n-propylamine (TPrA) system in aqueous solution, is been described. The quenching behavior can be observed with a 100-fold excess of bergenin over Ru(bpy) 3 2+ . In the presence of 0.1 m TPrA, the Stern–Volmer constant ( K SV ) of the ECL quenching is as high as 1.16 × 10 4 M −1 for bergenin. The logarithmic plot of the inhibited ECL versus logarithmic plot of the concentration of bergenin was linear over the range 3.0 × 10 −6 –1.0 × 10 −4 mol/L. The corresponding limit of detection was 6.0 × 10 −7 mol/L for bergenin (S/N = 3). In the mechanism of quenching it is believed that the competition of the active free radicals between Ru(bpy) 3 2+ /TPrA and bergenin was the key factor for the ECL inhibition of the system. Photoluminescence, cyclic voltammetry, coupled with bulk electrolysis, supports the supposition mechanism of the Ru(bpy) 3 2+ /TPrA–bergenin system. Copyright © 2015 John Wiley & Sons, Ltd.
研究领域:
分析化学
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药学
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高影响因子
MATERIALS CHEMISTRY AND PHYSICS
·
2021
·
IF 4.094
Wudong Liu,Jie Zhang,Xiangbiao Yin,Xinyi He,Xinpeng Wang,Yuezhou Wei
Through a simple hydrothermal reaction , LEuH-Cl (where LEuH and Cl denote layered europium hydroxide and a chlorine ion, respectively) was synthesized. Its structure and properties were similar to those of layered double hydroxides (LDHs). The material was composed of europium hydroxide host layers with a positive charge and a guest interlayer with chlorine ions. The hydrotalcite-like structure gives it excellent anion exchange abilities, and the host shows an intense photoluminescence (PL), mainly through 5 D 0 → 7 F J (J = 0,1,2,3, and 4). MnO 4 − or Cr 2 O 7 2− can be directly adsorbed by LEuH-Cl in an aqueous solution due to the large number of exchangeable chlorine ions, thereby resulting in a static quenching effect (SQE) and forming an inner filter effect (IFE) system, which leads to the direct quenching of the PL intensity. Based on this characteristic, the concentration of these two substances in an aqueous solution can be detected quickly and simply. Based on the experimental results, LEuH-Cl exhibited high selectivity and sensitivity toward MnO 4 − and Cr 2 O 7 2− in an aqueous solution. The detection limits of MnO 4 − and Cr 2 O 7 2− were calculated to be 3.43 and 1.19 μM, respectively. This proved the feasibility of using the material for the direct detection of multiple substances. The quenching caused by the anion exchange of layered rare-earth hydroxides (LRHs) was further explored.
研究领域:
材料科学
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环境科学
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Journal of Materials Chemistry B
·
2019
·Vol. 8
·期 16
·3542-3549
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IF 5.047
Mohamed Ibrahim Halawa,Fengxia Wu,Muhammad Nadeem Zafar,Islam M. Mostafa,Abubakar Abdussalam,Shuang Han,Guobao Xu
In this work, a glutathione (GSH) sensing nano-platform using lucigenin as a fluorescent probe in the presence of MnO2 nanosheets was reported for the first time. Unlike the earlier fluorescent detection systems based on MnO2 nanosheets, which depend on Förster resonance energy transfer (FRET) or the dynamic quenching effect (DQE), the mechanism of the quenching process of MnO2 nanosheets on lucigenin fluorescence was attributed mainly to a static quenching effect (SQE) with a minor contribution of the inner filter effect (IFE). A double exponential fluorescence decay of lucigenin was obtained in various MnO2 nanosheet concentrations as a result of their SQE and IFE. Based on this phenomenon and taking advantage of the redox reaction between GSH and MnO2 nanosheets, we have developed a switch-on sensitive fluorescent method for GSH via the recovery of the MnO2 nanosheet-quenched fluorescence of lucigenin. A good linearity range of 1.0–150.0 μM with a low limit of detection (S/N = 3) of 180.0 nM was achieved, revealing the higher sensitivity for GSH determination in comparison with the previously reported MnO2 nanosheet-based turn-on fluorescent methods. The developed fluorescent nano-platform exhibits excellent selectivity with successful application for GSH detection in human serum plasma, indicating its good practicability for GSH sensing in biological and clinical applications.
研究领域:
分析化学
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生物医学工程
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纳米技术
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高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2022
·
IF 4.831
Brian Musikavanhu,Yujie Zhang,Dongwei Zhu,Zhaoli Xue,Rui Yuan,Shengjun Wang,Long Zhao
A thiophene substituted naphthyl hydrazone derivative NHT was synthesized using a one-step route for the detection of trivalent chromium (Cr 3+ ). UV–visible absorption and emission spectra, density functional theory calculations as well as 1 H NMR titration confirmed that the probe underwent a turn-off response via the chelation enhanced fluorescence quenching effect upon exposure to Cr 3+ and the NHT -Cr 3+ complex was formed at a 1:1 binding stoichiometry. NHT exhibited a fast response rate of 2.3 min in buffer solution and a relatively low limit of detection of 41 nM. In addition, the Schiff base chemosensor exhibited excellent selectivity with high affinity towards Cr 3+ in the presence of other competing cations. Bioimaging of the probe in PC3 cells further demonstrated the potential real life application of the probe in detecting Cr 3+ .
研究领域:
分析化学
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生物医学
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高影响因子
JOURNAL OF FLUORESCENCE
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2022
·Vol. 32
·期 6
·2343-2350
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IF 2.525
Liu Tao,Zhang Shuai,Fan Xiaoyu,Yang Dou,Wang Min,Shao Xiaodong,Wang Shuhao,Yue Qiaoli
Carbon dots (CDs) were used to develop a sensitive sensing technique for detecting Cr(VI). CDs were made using a hydrothermal technique from citric acid and glutamic acid. These prepared CDs emitted blue fluorescence under excitation of 350 nm (λ em = 420 nm), and the fluorescence quantum yield was 48.41%. Transmission electron microscope was used to examine the morphology of the CDs, which had an average size of 2.21 ± 0.39 nm. The elementary composition and bonding structure of the CDs were conducted by XPS and FT-IR spectrum. Cr(VI) quenched the fluorescence of CDs through a static quenching effect and an inner filter effect, allowing Cr(VI) to be detected quantitatively. This approach was used to detect Cr(VI) in two samples of water, with the findings demonstrating that it is reliable and accurate. The fluorescence intensity change was linearly related to the concentration of Cr(VI) in the range from 0.5 to 400 μM, with the detection limit being 0.10 μM. This approach has the virtues of wide detection range, low cost and fast response. The strategy has a great application prospect for detecting Cr(VI) in practical samples.
研究领域:
分析化学
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环境科学
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高影响因子
FOOD AND AGRICULTURAL IMMUNOLOGY
·
2023
·
IF 3
Jiannan Chen,Xiuhua Xia,Peizhen Li,Hang Yu,Yunfei Xie,Yahui Guo,Weirong Yao,He Qian,Yuliang Cheng
As a type of environmentally deleterious compound, 4-nitrophenol (4-NP) has become a global concern due to its extreme toxicity to aquatic organisms and humans. Herein, we used naturally available crayfish shells as precursors to prepare a new type of carbon dots (CDs) by the hydrothermal method. The as-synthesized CDs exhibited strong blue fluorescence emission which can be sensitively quenched by 4-NP through the static quenching effect because of the formation of a ground state complex between CDs and 4-NP. Accordingly, a facile and rapid fluorescence sensor was developed to detect 4-NP from 0 μM to 50 μM with a limit of detection (LOD) of 0.16 μM. Furthermore, the proposed sensor was successfully applied for the detection of 4-NP in fresh crayfish meat and aquatic water samples.
研究领域:
环境科学
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分析化学
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高影响因子
NEW JOURNAL OF CHEMISTRY
·
2020
·Vol. 44
·期 16
·6635-6642
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IF 3.288
Mingyu Tang,Guojuan Ren,Fang Chai
This article reports a one-pot hydrothermal strategy for preparing fluorescence carbon dots with magnetic properties (Fe3O4-CDs). Ammonium ferric citrate (AFC) and urea served as the iron and nitrogen sources and both as carbon sources were put into the reaction solvent diethylenetriamine (DETA), which acted as a reductant and nitrogen provider in the process of the synthesis of Fe3O4-CDs. Further, a sensitive and rapid method based on the Fe3O4-CDs was utilized for the detection of Hg2+, simultaneously accompanied with a magnetic removal process. Good linearity was obtained in the range from 2.0 to 200.0 nM with a detection limit of 12.6 nM. The fluorescence quenching mechanism was proved to be caused by an inner-filter effect (IFE) and static quenching effect (SQE). More, this platform was successfully applied for the analysis of Hg2+ in a real sample with satisfying recovery results, thus demonstrating its utility as a convenient monitoring strategy.
研究领域:
分析化学
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环境科学
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材料科学
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高影响因子
JOURNAL OF INORGANIC BIOCHEMISTRY
·
2018
·
IF 3.063
Min Wang,Xiaofang Fei,Shaowu Lv,Ye Sheng,Haifeng Zou,Yanhua Song,Fei Yan,Qianlong Zhu,Keyan Zheng
In this study, we designed and synthesized two novel fluorescent magnetic nanoparticles . Fe 3 O 4 @SiO 2 -NH-GSH-CdTe (FSGC) (GSH = glutathione) nanoparticles were synthesized using amino-functionalized Fe 3 O 4 @SiO 2 nanoparticles and GSH-stabilized CdTe quantum dots (CdTe QDs), while flexible Fe 3 O 4 @SiO 2 -NH-GSH-CdTe-NH-NH 2 (FSGCN) nanoparticles were synthesized using the FSGC precursor and 1,6-hexamethylenediamine. These two kinds of nanoprobes exhibited excellent magnetic and fluorescent properties. By comparing the fluorescence quenching effect of folic acid (FA) on FSGC and FSGCN, we found that the quenching effect of FA on FSGC was acute and the process was too fast to determine the FA content. However, the quenching effect of FA on flexible FSGCN was mild and hence it could be used as a nanoprobe to determine FA concentration. At physiological pH, the fluorescence quenching effect of FA on the FSGCN nanoprobes was fitted according to the Stern–Volmer equation with a linear response in the concentration range of 0.14 to 4.20 μg mL −1 with a detection limit of 15.1 × 10 −9 g mL −1 (S/N = 3) under optimized experimental conditions. The proposed flexible nanoprobe was successfully used to determine the content of FA in folic acid tablets. Recovery was found to be in the range of 92.7%–105.6% with a relative standard deviation of 1.12%–3.84%. Owing to their good stability, environment-friendly characteristics, high selectivity, and good optical properties and biocompatibility, these nanoprobes have potential for usage in practical applications.
研究领域:
生物医学工程
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分析化学
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2022
·
IF 4.831
Wenchao Jia,Xiangying Jin,Yuhua Wu,Danping Xie,Wenhua Yin,Bo Zhao,Zhonghui Huang,Lijun Liu,Yanyan Yang,Tonghui Cao,Xidan Feng,Sheng Chang
Here, we report a novel aptasensor based on decahedral silver nanoparticles (Ag 10 NPs) enhanced fluorescence polarization (FP) for detecting PCB-77. Using aptamer modified Ag 10 NPs hybridized with DNA sequence labeled fluorescent group as an analytical probe, polychlorinated biphenyls (PCB-77) could be detected with high sensitivity and selectivity. The linear range of determination was 0.02 ng/L to 390 ng/L and the limit of detection was 5 pg/L. In addition, through the optimization of the experiment condition and signal probe DNA (pDNA), we found that the maximum FP signal could be generated when the distance between fluorescein and the surface of Ag 10 NPs was 3 nm. When the aptamer was immobilized on the surface of Ag 10 NPs could be strengthened the anti-interference performance of aptamer nanoprobe and further improved the detection ability. At the same time, we also compared the detection performance of the traditional FP signal enhancer streptavidin (SA) analysis system. The fluorescence polarization aptasensor could detect PCB-77 samples efficiently in complex environmental water, which shows a good application prospect.
研究领域:
分析化学
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环境科学
·
纳米技术
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高影响因子
TALANTA
·
2017
·
IF 4.162
Weiheng Kong,Di Wu,Guoliang Li,Xuefeng Chen,Peiwei Gong,Zhiwei Sun,Guang Chen,Lian Xia,Jinmao You,Yongning Wu
A rapid, facile and ultrasensitive fluorescence sensing system based on nitrogen-doped carbon dots (N-doped CDs) for the detection of ascorbic acid (AA) was developed. The highly photoluminescent N-doped CDs with excellent solubility in water and good biocompatibility were prepared by a one-step hydrothermal synthesis and gave the fluorescence quantum yield of 47%. The addition of AA can intensively suppress the fluorescence of the N-doped CDs through the synergistic effect of the inner filter effect (IFE) and the static quenching effect (SQE). Benefited from the remarkable synergistic effect of IFE and SQE, a facile and ultrasensitive sensor was constructed successfully for AA sensing. The detection procedure was achieved within 2 min. The linear response range of AA was obtained from 10 −3 to 10 −8 M with a detection limit of 5 nM. This developed method enjoyed many merits including more simplicity, lost cost, high sensitivity, good selectivity, rapid response and excellent biocompatibility. Notably, the proposed fluorescent sensor exhibits excellent performance and applicability for AA determination in human serum and rat brain microdialysate, and may provide a fast yet facile route for AA detection in physiological and pathological fields.
研究领域:
分析化学
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生物医学
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PubMed
高影响因子
RSC Advances
·
2021
·Vol. 11
·期 37
·22960-22968
·
IF 3.361
Haixin Lu,Hanqiang Zhang,Yufei Li,Feng Gan
A novel fluorescent probe based on sulfur quantum dots (SQDs) was fabricated for sensitive and selective detection of tetracycline (TC) in milk samples. The blue emitting SQDs were synthesized via a top–down method with assistance of H2O2. The synthesized SQDs showed excellent monodispersity, water solubility and fluorescence stability, with a quantum yield (QY) of 6.30%. Furthermore, the blue fluorescence of the obtained SQDs could be effectively quenched in the presence of TC through the static quenching effect (SQE) and inner filter effect (IFE) between TC and SQDs. Under the optimum conditions, a rapid detection of TC could be accomplished within 1 min and a wide linear range could be obtained from 0.1 to 50.0 μM with a limit of detection (LOD) of 28.0 nM at a signal-to-noise ratio of 3. Finally, the SQD-based fluorescent probe was successfully applied for TC determination in milk samples with satisfactory recovery and good relative standard deviation (RSD). These results indicate that the SQD-based fluorescent probe shows great potential in practical analysis of TC in real samples with high rapidity, selectivity, and sensitivity.
研究领域:
分析化学
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食品科学
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PubMed
高影响因子
Analytical Methods
·
2024
·
IF 2.7
Huifeng Xu,Weihua Huang,Rui Pan,Ronglin Chen,Lili Wang,Yun Yu,Xihai Li,Xi Zhu
A stable dual-emission fluorescent system, R6G/Eu-MOF, was obtained by simple mixing Eu-MOF with fluorescent rhodamine 6G (R6G). This system not only achieved robust dual luminescence performance at 430 nm (Eu-MOF) and 555 nm (R6G) under single-wavelength excitation, but also endowed it significantly improved fluorescence stability. Orientin (OT), a bioactive traditional Chinese medicine (TCM) component, was found to efficiently quench the dual fluorescent emissions via the synergistic effect of dynamic quenching effect, photo-induced electron transfer and molecular interactions. Therefore, a rapid fluorescent assay for OT was developed based on the variations in fluorescence signals at 430 nm and 555 nm, as well as the alterations in the ratio between these two signals. This method can achieve highly sensitive determination of OT in the linear range of 1.1-220 µM, with a LOD of 0.26 µM at 430 nm and 0.16 µM at 555 nm (3σ/N). The R6G/Eu-MOF hybrid exhibits significantly lower detection limits and a broader linear range OT than either R6G or Eu-MOF alone. This work presents a simple strategy to improve the water stability of Eu-MOF, and also provides a rapid analysis of small molecule drug using a fluorescence approach based on dual-emission MOF hybrid system.
研究领域:
分析化学
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药物分析
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材料科学
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高影响因子
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