npj Science of Food
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2025
·Vol. 9
·期 1
·1-10
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IF 7.8
Chen Lichun,Yao Feng,Xue Songwen,Yao Kuang,Huang Yun,Zhao Huimin,Shao Qiong
Sugar alcohols are natural sweeteners with various physiological functions, commonly used in low-calorie foods and pharmaceuticals. Current research primarily focuses on their sweetening properties and metabolic effects, often overlooking their interactions with cell membranes. This study built a giant phospholipid vesicle model to examine vesicle deformation in erythritol (Ery) and xylitol (Xyl) environments. The permeation of these sugar alcohols through real cell membranes was also investigated. Fluorescence microscopy and zeta potential measurements showed that osmotic stress from concentration gradients disrupted vesicle membrane structure. Ery and Xyl reduced ROS levels in HEK-293 cells and influenced membrane permeability. Notably, Xyl increased vesicle adsorption on the cell membrane at the same concentration. The findings indicate that sugar alcohols interact with membrane lipids through hydrogen bonds or other non-covalent interactions, modifying cell membrane structure and properties, thus providing a theoretical foundation for understanding their role in physiological environments.
研究领域:
生物物理学
·
细胞生物学
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DOI
PubMed
高影响因子
Matter
·
2025
·
IF 17.5
Xinghe Xu,Fu-Lin Gao,Lin Tian,Zhi-Yue Yang,Zhong-Zhen Yu,Jie Shang,Run-Wei Li,Xiaofeng Li
Flexible, self-powered thermoelectric temperature sensors with high reliability are increasingly recognized as essential components in tactile perception, wearable technologies, and medical monitoring. To fulfill the performance requirements of these applications—specifically, achieving high Seebeck coefficients and superior resolution—traditional fabrication strategies typically rely on intricate molecular engineering, microscale structural optimization, or macroscale topological design. However, these approaches often involve complex manufacturing processes and elevated production costs, constraining large-scale deployment. Here, we propose a simple multilayer assembly approach that harnesses a self-permeation effect to enable the facile and cost-effective fabrication of flexible thermoelectric sensors with significantly improved sensitivity and resolution. By inducing intensive p-n heterojunctions through self-permeation and leveraging phonon scattering at multilayer-structured interfaces, the obtained sensor exhibits an unprecedented sensitivity of 1,203.6 μV K −1 and an ultimate temperature difference detection capability of 0.001 K, showcasing great potential for applications in three-dimensional environmental monitoring and bionic robotic tactile sensing.
研究领域:
材料科学
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电子工程
·
传感技术
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DOI
高影响因子
INORGANIC CHEMISTRY
·
2024
·
IF 4.3
Jinlong Liu,Ziyu Luo,Jiayun Wu,Dong Qian,Weixiong Liao,Geoffrey I. N. Waterhouse,Xiangxiong Chen
The oxygen reduction reaction (ORR) plays a vital role in many next-generation electrochemical energy conversion and storage devices, motivating the search for low-cost ORR electrocatalysts possessing high activity and excellent durability. In this work, we demonstrate that iron–cobalt phosphide (FeCoP) nanoparticles encapsulated in a N-doped carbon framework (FeCoP@NC) represent a very promising catalyst for the ORR in alkaline media. The core–shell structured FeCoP@NC catalyst offered outstanding ORR activity with a half-wave potential (E1/2) of 0.86 V vs reversible hydrogen electrode (RHE) and excellent stability in a 0.1 M KOH electrolyte, outperforming commercial Pt/C and many recently reported noble-metal-free ORR electrocatalysts. The superiority of FeCoP@NC as an ORR electrocatalyst relative to Pt/C was further verified in prototype zinc-air batteries (ZABs), with the aqueous and flexible ZABs prepared using FeCoP@NC offering excellent stability, impressive open circuit voltages (1.56 and 1.44 V, respectively), and high maximum power densities (183.5 and 69.7 mW cm–2, respectively). Density functional theory calculations revealed that encapsulating FeCoP nanoparticles in N-doped carbon shells resulted in favorable electron penetration effects, which synergistically regulated the adsorption/desorption of ORR intermediates for optimal ORR performance while also boosting the electronic conductivity. Our findings offer valuable new insights for rational design of transition metal phosphide-based catalysts for the ORR and other electrochemical applications.
研究领域:
材料科学
·
电化学
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PubMed
高影响因子
FOOD CHEMISTRY
·
2025
·
IF 9.8
Qifu Yang,Yuying Zhang,Xuhui Huang,Aihua Deng,Ruisong Wang,Wensi Xu,Lei Qin
Balancing flavor and health in Marinated Crayfish (MC) requires precise salt addition. This study deciphered how salt (0–4 %) shapes flavor via integrated metabolic and volatile profiling. Multivariate statistics identified 15 key non-volatile and 11 pivotal volatile metabolites. Mechanistically, salt modulates flavor through salting-out and osmotic effects, alongside lipid oxidation changes. At lower levels (0–1 %), salt retained endogenous free amino acids and nucleotides, though the product tasted bland due to insufficient saltiness. Conversely, higher salt (3–4 %) enhanced saltiness but reduced endogenous compounds and impeded key exogenous volatiles, including β-pinene, limonene, sabinene, 4-carene, copanene and p-cymene. Critically, increased salt shifted lipid oxidation pathways, elevating 2-decanone, p-menth-1-en-9-al, and limonene oxide, while suppressing decanal and 1-octen-3-ol. Collectively, NaCl imparts saltiness but depletes characteristic flavor compounds. Therefore, 2 % salt is identified as the optimal target for MC, balancing saltiness with flavor complexity and providing a practical guideline for future optimization.
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高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2022
·Vol. 57
·期 2
·1019-1035
·
IF 4.682
Wang Zhen,Tao Jie,Shen Yizhou,Liu Senyun
Composite film heater is becoming the focus of research in the deicing field, owing to its advantages of high electro-thermal efficiency and lightweight. In this work, a new composite film heater with ultralow conductive filler was designed and prepared by mixing insoluble ethyl vinyl acetate (EVA) and soluble polyvinylidene fluoride (PVDF) in dimethylformamide (DMF). It is common sense that many insoluble EVA fillers degrade mechanical properties due to the macro-interface defect. The molecular dynamic simulation indicated that interfacial blending regions were formed more easily between molten EVA and soluble PVDF on account of the similar solubility parameter and stronger adsorption energy between Vinyl acetate segmer and PVDF segmer. The semi-compatible system was favorable to eliminate the macro-interface defect between EVA and PVDF partially. The film heater showed better tensile strength, flexibility, and bending durability after heat treatment of 80 °C. Moreover, the film heater had an outstanding heating effect, fast electro-thermal response time, low-energy consumption, and excellent thermal cycling stability. It achieved the steady-state temperature of 117.4 °C and the heating rate of 1.348 °C/s when the ratio of PVDF to EVA was 1:1 and the amount of CNT was only 10% at 28 V. The optimal ratio of CNT and EVA could construct a double reticular structure, consists macroscopic and microscopic conductive network at the same time, thereby reducing the content of conductive filler significantly. Furthermore, the deicing experiment manifested that the icicle fell after 29 s at 28 V, much shorter than without loading current. The integrated CNT@EVA/PVDF composite film heater contributes to a better understanding of the low percolation effect and the distribution mechanism between molten EVA and soluble PVDF, which could conduce to the development of novel electro-thermal deicing film in future.
研究领域:
材料科学
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能源工程
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DOI
高影响因子
ANALYTICA CHIMICA ACTA
·
2025
·
IF 6
Linan Sun,Yafei Lou,Siyu Chen,Hongyue Weng,Jiahao Li,Zhihui Lin,Junfei Tian,Rong Cao
Background While paper-based colorimetric assays have seen significant progress in recent years, persistent challenges including the coffee-ring effect and infiltration effect continue to affect the color uniformity of detection results, leading to decreased sensitivity and accuracy of the detection. Recent advancements in suppressing these two effects mainly depend on chemical modification of cellulose fibers or application of specific functional coatings. However, the former's complex procedures impede large-scale implementation, while the latter's non-cellulosic additives risk unpredictable interactions with analytes or interference in colorimetric reactions. Result Herein, we propose a “like cures like” strategy by modifying cellulose-based paper substrates with nanocellulose materials, that is, cellulose nanofibers (CNFs) and cellulose nanocrystals (CNCs). This approach aims to suppress the capillary flow of the liquid sample and prevent penetration of chromogenic products within the paper substrate. Systematic characterization of the modified paper substrates focused on key aspects including fluid transport capacity and chromogenic performance of the resulting sensors. The optimized modified substrates were tested for detecting Ni 2+ using dimethylglyoxime and Fe 2+ using bathophenanthroline. The distribution of their colorimetric products in the paper substrates demonstrated effective suppression of both the coffee-ring and infiltration effects. Compared to untreated counterparts, the CNCs-treated paper sensors exhibited enhanced detection accuracy and sensitivity. The linear correlation coefficients were 0.99 for Ni 2+ and Fe 2+ detection, with limits of detection of 0.4520 ppm for Ni 2+ and 0.1564 ppm for Fe 2+ , respectively. Significance This study presents a novel strategy for constructing paper-based colorimetric sensors by in situ formation of micro-nano composite structures via nanocellulose modification. By leveraging the shared cellulose origin between the substrate and the modifier, this approach eliminates the need for foreign additives and enhances the colorimetric performance through improved uniformity and signal intensity. Consequently, this method enhances the accuracy and sensitivity of paper-based colorimetric detection while avoiding potential interferences from non-cellulosic additives.
研究领域:
分析化学
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材料科学
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纳米技术
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生物传感器
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表面化学
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PubMed
高影响因子
危险品化学品经营许可证（带存储）