JOURNAL OF MOLECULAR LIQUIDS
·
2024
·
IF 5.3
Yong Cao,Qianfeng Chen,Qing He,Gaojin Zhou,Ali Ahmad,Shun Yao
Considering the controversial safety and risk solutions of ionic liquids (ILs), more essential basic researches are required as their applied fields become broader and applied scale grows larger. Under this background, the permeation behaviors of six common imidazole ILs on porcine gastric and enteric membranes together with the feasibility of their removal by adsorption with montmorillonite were investigated in vitro. Through the single-factor investigation of different cations, anions and ionic liquid concentrations, the current results show that the IL of 1-ethyl-3-methylimidazolium bromide ([Emim]Br) has the strongest permeation capacity on the gastric membrane during the tests. The cumulative permeation amount of Q n can reach 0.72 mg/cm 2 , and the cumulative permeation percentage alsoreaches 95.77 %; the whole permeation process conforms to the Hixcon-Crowell model. As comparison, the maximum cumulative penetration percentage of [Emim]Br on enteric member was determined as 89.11 %, and related models was also compared. In order to remove the potential IL in digestive tract, montmorillonite was screened out from those popularily used antidotes in clinic and the adsorption of [Emim]Br in gastric fluid by montmorillonite has been proved more consistent with the second-order kinetics and Langmuir model. The results of molecular simulation, infrared spectrum (IR), X-ray diffraction (XRD) and thermogravimetric (TG) characterization exhibit that [Emim]Br has been successfully adsorbed into the interlayer of montmorillonite. As a whole, the study provided a scientific and effective way to diminish the hidden danger of ionic liquid entering the blood through the digestive system.
研究领域:
药理学
·
毒理学
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING SCIENCE
·
2021
·
IF 4.311
Qiang Huang,Xinxin Li,Pengpeng Zhang,Shichao Zhang,Yahua Liu,Peng Cui,Jin Ran
Transition metal dichalcogenide (TMD) derived stratiform membranes exhibit sub-nanometer scale interlayer distances and exceptional anti-swelling property in water environments but they are frustrated in ion rejections. Herein, the in-plane regulating concept to improve ion exclusion of TMD laminates was proposed. We demonstrate this concept using flexible and hydrophilic polyvinyl alcohol (PVA) polymers as the intercalators to implant TMDs. The resulting TMD/PVA membranes show obviously decreasing ion permeation. Taking the TaS 2 /PVA membrane as an example, its monovalent, divalent and trivalent ion transport rates reduce by 87, 131 and 168 times respectively compared with the pristine TaS 2 membrane. Additionally, the ion permeation behaviors of TMD/PVA membranes reveal long-term and cyclic stability. For the practical desalination process under the forward osmosis mode, the TaS 2 /PVA membrane shows an extraordinarily high water flux of 3.9 L m −2 h −1 together with a promising NaCl rejection of 98.7%, which is superior to the existing two dimensional membranes.
研究领域:
材料科学
·
环境工程
✓ 已验证
产品关联
DOI
高影响因子
ACS Omega
·
2025
·
IF 4.3
Yunlong Chen,Jinliang Li,Liman Liu,Yi Li
Coal seam mining generates significant dust, posing serious threats to the safety of mining and the well-being of miners. This study suggests a delayed cross-linking approach to convert the dust suppressant into a gel within the coal seam, introduces a controllable slow-release ionic cross-linking dust suppressant, investigates its seepage behavior, and evaluates its dust suppression effectiveness in a coal seam. The experimental results show that the dust suppressant exhibits low viscosity and high fluidity during injection into the coal seam, facilitating effective infiltration into the seam. By managing the release rate of Ca2+ in the slow-release system, the gelation time of the dust suppressant within the coal seam can be controlled efficiently. While reducing the viscosity, increasing injection pressure promotes material seepage in the coal seam. The optimized injection pressure for the dust suppressant is 7 MPa, and its seepage behavior in the coal seam postinjection resembles that of water. The dust suppressant cross-links and reacts to form a macromolecular mesh structure in tiny internal pores and on the coal seam surface, enhancing the water retention and toughness of the coal seam. These combined mechanisms effectively reduce dust production during coal seam mining, achieving a source reduction of dust production.
研究领域:
采矿工程
·
环境科学
✓ 已验证
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2017
·
IF 4.529
Ruyan Hou,Mengmeng Tong,Wanjun Gao,Lei Wang,Tianxi Yang,Lili He
To investigate the degradation and penetration behaviors of the organophosphate insecticide dimethoate applied on spinach leaves, in situ SERS and LC-MS methods were used to detect dimethoate residue on&in spinach leaves picked on different days after treatment (DAT). The SERS and LC-MS methods determined that the dimethoate degradation rate followed first-order kinetics, with a half-life of 3.56 or 4.13 days, depending on the respective method. The correlation coefficient of quantification value of these two methods was 0.9562. With the SERS method, we detected most of the penetrated dimethoate in the depth of 60–110 μm. With the LC-MS method, we detected dimethoate up to 0.17 ng in leaves and that the dimethoate on:in ratio of spinach leaves ranged from 562.25 on 0 DAT to 5.23 on 14 DAT. The combination of these two methods facilitated a better understanding of the behavior and biological fate of pesticides in a complex biological system.
研究领域:
植物学
·
农药科学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
·
2016
·
IF 3.773
Chao Liu,Peng Quan,Liang Fang
The aim of this study was to investigate the influence of drug physicochemical properties on drug release behaviors and their relationship with skin permeation behaviors, which provided transdermal enhancement strategies for the design of transdermal drug delivery system . Six model drugs with different physicochemical properties were selected and hydroxyl pressure sensitive adhesive (PSA) was synthesized. Horizontal diffusion cell was used to evaluate drug release and skin permeation behaviors. The relationship between physicochemical properties and release behaviors was conducted with regression analysis. Release behavior of 0.25% drug loading was linear related with polar surface area, which represented the hydrogen bond . Release behavior of 2.0% drug loading was dependent on the polarizability and log P , which represented dipole-dipole interaction and lipophilicity , respectively. According to the results of Fourier transform infrared spectroscopy , it was inferred that hydrogen bond was limited in controlling release of drug due to the limited quantity of bonding site, thus dipole-dipole interaction and log P became dominate control factors. Combining the drug release study and drug skin permeation study, it was concluded that drugs with different physicochemical properties should be applied with different transdermal enhancement strategies, which was useful for the design of transdermal drug delivery system.
研究领域:
药剂学
·
药物递送系统
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COMPOSITES COMMUNICATIONS
·
2021
·
IF 6.617
Guohua Fan,Zhongyang Wang,Guodong Zhang,Yao Liu,Runhua Fan
Dielectric and magnetic properties of percolative nickel/yttrium iron garnet cermets were investigated. With nickel content increasing, microstructure evolution of the cermets exhibited characteristics of percolation , resulting in electrical conductivity increased dramatically and conduction mechanism changed from hopping to metallic behaviors. Negative permittivity and negative permeability were observed. Negative permittivity was caused by the plasmonic state of delocalized electrons. Negative permeability was attributed to magnetic resonance of ferromagnetic constituents and diamagnetic responses of eddy currents induced in interconnected nickel networks. The obtained double negative metacomposites enriched metamaterials and have great potential in electromagnetic shielding, cloaking, and attenuation applications.
研究领域:
材料科学
·
电磁学
✓ 已验证
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2021
·
IF 6.707
Kejun Shi,Shu Xiao,Qingdong Ruan,Hao Wu,Guohua Chen,Chilou Zhou,Saihua Jiang,Ke Xi,Mohan He,Paul K. Chu
A method for in situ deposition of multi-layered graphene (MLG) coatings is demonstrated to mitigate hydrogen embrittlement of the X70 pipe steel. Carbon is implanted into the nickel catalytic layer pre-deposited by electroplating on the surface of the pipe steel, followed by annealing to segregate and form MLG. The MLG coatings are investigated systematically with respect to the surface morphology, phase structure, hydrogen resistance, corrosion resistance, and molecular dynamics simulation. In the stacked MLG structure, the in situ grown graphene layers interpenetrate each other to boost the coating adhesion and hydrogen resistance. Diffusion and the solid solution formed between the Ni coating and substrate improve the adhesion strength after annealing. The diffusion coefficient and permeability are reduced by 123 times and 48 times, respectively. Slow strain rate tests demonstrate outstanding resistance against hydrogen embrittlement because the MLG coatings inhibit hydrogen evolution, extend the diffusion path, decrease the permeation area, and enhance hydrogen adsorption. Moreover, electrochemical tests indicate that the MLG coatings have better corrosion resistance. These results reveal a viable strategy to use graphene to protect commercial steels from hydrogen embrittlement.
研究领域:
材料科学
·
工程学
✓ 已验证
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Longhui Luo,Dongmei Chen,Xiufang Yan,Chao Kang,Wei Tian,Qian Liu,Xiaoying Yang,Tingting Chen,Youhua Long
Triazole pesticides are widely used to control pathogenic fungi in agricultural production, but the irrational use of these pesticides will have many negative effects on human health and ecological environment. In this study, we constructed a relatively complete visual monitoring system for triazole pesticides based on surface-enhanced Raman spectroscopy (SERS). Silver nanoparticles (Ag@ICNPs) modified with iodide and calcium ions showed stronger SERS enhanced ability and better reproducibility, and the characteristic peaks of eight different triazole pesticides were captured simultaneously. Principal component analysis (PCA) and support vector machine (SVM) were used to identify these pesticides. The developed method has strong quantitative analysis ability, excellent detection sensitivity and wide detection range, and has been successfully applied to the determination of pesticide residues in fruits and vegetables. In addition, dynamic SERS imaging technology combined with multivariate curve resolution-alternating least squares (MCR-ALS) to visually monitor the penetration behavior of triazole pesticides could remove the influence of interfering substances, thus obtaining an accurate distribution map of pesticides, which promoted the quantification of pesticide penetration process. The diffusion ability of different systemic pesticides into fruits and vegetables was revealed. Electrochemical (EC) assisted SERS of triazole pesticides showed that potential-induced molecular reorientation of pesticide molecules on the electrode surface was induced by the polarization of active substrate, which significantly improved the SERS signal of pesticides. Overall, this systematic pesticide monitoring study not only provides an effective innovative scheme for controlling the detection of hazardous substances in agricultural products, but also brings significant prospects for food safety guarantee.
研究领域:
食品安全
·
分析化学
·
农业科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2020
·
IF 4.65
Yunpeng Qu,Yulin Wu,Jiada Wu,Kai Sun,Runhua Fan
Metacomposites with simultaneous epsilon-negative and mu-negative property have drawn tremendous attentions due to their promising applications in electromagnetic field. Herein, Ni/CaCu 3 Ti 4 O 12 (Ni/CCTO) metacomposites were prepared by low-temperature pressureless sintering method. It was observed that Ni chains were gradually interconnecting to each other with increasing Ni content, and a percolation behavior was observed. Epsilon-negative property was obtained above percolation threshold attributing to the synergistic effect of induced electric dipole and low-frequency plasma oscillation in Ni networks, which was explained by the superposition of Drude and Lorentz model. Mu-negative property was observed above ∼34 MHz and ∼120 MHz for 60 wt% and 70 wt% Ni/CCTO composites respectively, which may originate from the combined effects of diamagnetic response, domain wall motion and gyromagnetic spin rotation. Hence, simultaneous epsilon-negative and mu-negative property at radio-frequency region was realized in Ni/CCTO metacomposites. Besides, the composites presented hopping conduction behavior, and then changed into metal-like conduction behavior with increasing Ni content. The impedance response of Ni/CCTO composites clarified the correlation between epsilon-negative and inductive character. This work could broaden the scope of metacomposites and pave its way to potential applications of electromagnetic shielding, novel antenna, and high- k capacitors.
研究领域:
材料科学
·
电磁学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2023
·
IF 6.1
Lichun Chen,Songwen Xue,Binhao Dai,Yifei Wang,Huimin Zhao
Molecular permeation through phospholipid membranes is a fundamental biological process for small molecules. Sucrose is one of the most widely used sweeteners and a key factor in the pathogenesis of obesity and diabetes, yet a detailed understanding of its mechanism involved in permeability into phospholipid membranes is still lacking. Here, using giant unimolecular vesicles (GUVs) reconstituting membrane properties, we compared the osmotic behavior of sucrose in GUVs and HepG2 cells to explore the effect of sucrose on membrane stability in the absence of protein enhancers. The results suggested that the particle size and potential of GUVs and the cellular membrane potential changed significantly with increasing the sucrose concentration (p < 0.05). In microscopic images of cells containing GUVs and sucrose, the fluorescence intensity of vesicles was 537 ± 17.69 after 15 min, and the value was significantly higher than that of microscopic images of cells without sucrose addition (p < 0.05). These changes suggested that the permeability of the phospholipid membrane became larger under a sucrose environment. This study provides a theoretical basis for better insight on the role of sucrose in the physiological environment.
研究领域:
生物物理学
·
细胞生物学
·
分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
·
2023
·Vol. 107
·期 1
·475-487
·
IF 3.9
Ling He,Ling Pan,Wei Zhou,Maolin Chen,Qinzhao Zhang,Wenqian Pan,Peng Xiao,Yang Li
The interaction and infiltration behavior between typical calcium–ferrum–alumina–silicate (CFAS) and Yb 4 Hf 3 O 12 ceramics at 1300, 1400, and 1500°C for different duration times were investigated. At 1300°C, the CFAS melt first crystallized and then generated massive anorthite with high-melting point, reducing the wettability of CFAS melt and physically blocking CFAS penetration paths. As the temperature increased to 1400°C and 1500°C, the wettability of the molten CFAS correspondingly increases. A continuous reaction layer, composed of apatite, fluorite, and garnet, was formed over Yb 4 Hf 3 O 12 ceramic due to the penetration of CFAS melt. Furthermore, the infiltration rate of CFAS decreases with increasing corrosion time because of the barrier effect primarily derived from the as-mentioned continuous reaction layer.
研究领域:
材料科学
·
陶瓷材料
·
高温材料
·
无机化学
·
表面化学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）