ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2017
·Vol. 24
·期 30
·23872-23879
·
IF 2.741
Li Dan,Bi Ran,Chen Hongxing,Mu Lei,Zhang Lina,Chen Qin,Xie Haibo,Luo Yongju,Xie Lingtian
Risk assessing newly synthesized chemicals prior to their applications is extremely important, if we want to ensure substitution of risky chemicals with more benign ones. During the past two decades, many analogs of bisphenol A (BPA) have been manufactured, while their toxicity remains less studied. The aim of this study was to compare the acute toxicity of a synthesized lignin-derived BPA (LD-BP) with that of BPA in representative aquatic organisms including two algal species ( Chlorella pyrenoidosa and Scenedesmus obliquus ), a cladoceran species ( Daphnia magna ), and the Japanese medaka ( Oryzias latipes ). The results revealed that the two algal species showed different responses to the two chemicals. For C. pyrenoidosa , both BPA and LD-BP stimulated growth within 48 h of exposure, except for the 50 mg L −1 of LD-BP treatment. After 96 and 144 h of exposures, BPA stimulated the growth of C. pyrenoidosa at low-exposure concentrations but inhibited its growth at high concentrations, while LD-BP caused a concentration-dependent response in C. pyrenoidosa . S. obliquus exhibited a monotonic concentration-response curve for both BPA and LD-BP exposures. For both D. magna and O. latipes , concentration-responses were monotonic with 96 h–LC 50 of BPA and LD-BP of 11.7 and 5.0 mg L −1 and 9.4 and 4.1 mg L −1 , respectively. Our results demonstrate that LD-BP is more toxic than BPA in the representative aquatic organisms, and it can pose higher ecological risk to the aquatic ecosystem than BPA.
研究领域:
环境科学
·
毒理学
✓ 已验证
DOI
PubMed
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
·
2021
·
IF 7.963
Bowen Xiao,Rongyan Yang,Pengyu Chen,Jing Yang,Binbin Sun,Kunkun Wang,Tong Zhang,Lingyan Zhu
Silver nanoparticles (AgNPs) released into the environment are subject to environmental transformation processes before accumulating in aquatic organisms and transferring along the food chain. Lack of understanding on how environmental transformation affects trophic transfer of AgNPs hinders accurate prediction of the environmental risks of these widely present nanomaterials . Here we discover that pristine AgNPs as well as their sulfidation products (Ag 2 S-NPs) and dissolution products (Ag + ) tend to be accumulated in Daphnia magna and subsequently transferred to zebrafish. In D . magna , Ag + exhibits the highest bioaccumulation potential whereas Ag 2 S-NPs show the lowest bioaccumulation. Surprisingly, the biomagnification factor of Ag + along the D . magna -zebrafish food chain appears to be significantly lower relative to AgNPs and Ag 2 S-NPs, likely due to the limited release of Ag from D . magna to zebrafish during digestion. Moreover, AgNPs and their transformation products mainly accumulate in the internal organs, particularly intestine, of zebrafish. Adsorption of AgNPs on the surface of the intestinal cell membrane mitigates depuration of AgNPs and, at least in part, leads to the larger biomagnification factor of AgNPs, relative to their transformation products. This research highlights the necessity of considering environmental transformation processes of nanomaterials in assessing their bioavailability and risk.
研究领域:
环境科学
·
生态学
·
毒理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ECOTOXICOLOGY
·
2024
·
IF 2.4
Yang Liu,Liu Kexin,Shi Lina,Chen Ming,Liu Junyan,Dai Shiniu,Xi Yilong,Wen Xinli
N-(1,3-dimethylbutyl)-N’-phenyl-p-phenylenediamine (6PPD) and Zn 2+ , extensively used in the tire manufacturing process, are frequently detected in freshwater environments. However, the intergenerational effects of isolated 6PPD exposure and joint 6PPD and Zn 2+ exposure at concentrations approximating environmental levels remain unknown. This study assessed the chronic toxicity and intergenerational effects of 6PPD (0.02–20 μg/L) and a mixture of 6PPD and Zn 2+ (5 μg/L) over three generations in Daphnia magna bioassays. In the F0 generation, a dose-dependent decline in total offspring number was observed with 6PPD exposure alone, while co-exposure with Zn 2+ exacerbated the reproductive toxicity of 6PPD. Across three generations, low-dose (0.02 µg/L) 6PPD alone and combined with Zn 2+ induced a cumulative degenerative maternal effect. Conversely, high-dose (20 µg/L) 6PPD, both independently and in combination with Zn 2+ , exhibited an adaptive maternal effect. Notably, the grandmaternal effect emerged exclusively in the co-exposure group treated with 20 μg/L 6PPD and 5 μg/L Zn 2+ , with no such effect in the group exposed to 20 μg/L 6PPD alone, suggesting that Zn 2+ may enhance the potential toxicity of 6PPD. Overall, this study provides novel insight into the intergenerational impacts of environmentally relevant levels of 6PPD alone and in combination with a heavy metal, elucidating the environmental risks posed by tire-derived chemicals through their synergistic effects on transgenerational toxicity.
研究领域:
环境科学
·
毒理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
·
2021
·
IF 7.963
Hui Lin,Yinqiu Yuan,Xiaoman Jiang,Jian-Ping Zou,Xinghui Xia,Shenglian Luo
Microplastics (MPs) are the significant environmental factor for bioavailability of hydrophobic organic contaminants (HOCs) in aquatic environments. Nevertheless, the bioavailability of microplastic-associated HOCs remains unclear. In this research, the freely dissolved pyrene concentrations were kept stable with passive dosing devices, and the pyrene content in D. magna tissues as well as D. magna immobilization were analyzed to quantify bioavailability of pyrene (a representative HOC) associated with naturally-aged polystyrene (PS) MPs. Furthermore, the uptake mechanisms of pyrene associated with MPs of different sizes were explored by investigating the distribution of MPs in D. magna tissues with scanning electron microscopy. Especially, a new schematic model of bioavailability process was established. The results demonstrated that a part of pyrene associated with 0–1.5 μm MPs could directly cross cell membrane through endocytosis from intestine and exposure solutions to D. magna tissues except the 10–60 and 60–230 μm MPs. The bioavailability of microplastic-associated pyrene was ordered as 0–1.5 μm (20.0–21.6%) > 10–60 μm (10.7–13.8%) > 60–230 μm MPs (6.0–9.8%), which were essentially resulted from the difference in uptake mechanisms of pyrene associated with MPs of different sizes. This work suggests that the bioavailability of microplastic-associated HOCs should be considered when assessing water quality and environmental risk of HOCs in natural waters.
研究领域:
环境科学
·
毒理学
✓ 已验证
DOI
PubMed
高影响因子
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
·
2023
·
IF 4.7
Shaoquan Liu,Jianlu Zhang,Ruijiao Li,Chunyun Zhang,Lixin Wang,Hao Liang,Guangpeng Feng,Dongmei Xiong
Due to chemical and photochemical stability, triazophos has been frequently detected in rivers and oceans over the years with extensive use for pest control in agriculture , and it has become a worldwide ecological concern to the aquatic environment . Until now, fewer data are available regarding the potential long-term adverse effects of triazophos on aquatic invertebrates , which plays an essential role in aquatic food webs , as a key group for water ecosystems. In this experiment, the F 1 - and F 2 progenies of Daphnia magna were recovered when daphnias (F 0 ) exposure to triazophos at environmental-related concentrations (0.1 and 1.0 μg/L) for 21 d; and the indexes related to phenotypic traits, reproduction and gene expression were measured in tested animals. The results showed that heart rate and total number of neonates in exposed F 0 -daphnias were significantly lower than those of control group, and the detoxification genes ( HR96 and P-gp ) were up-regulated while genes related reproduction ( Vtg ) and molting ( Nvd and Shd ) were significantly down-regulated. The heart rate and individual size of F 1 -daphnias (<24 h) were significantly reduced in the treatment group. After 21-d recovery, the heart rate and expression of HR96 , P-gp, Vtg, Nvd and Shd were declined in F 1 -daphnias. There was no obvious difference of morphological traits and heart rate between treatment and control in F 2 -daphnias (<24 h). In summary, daphnias (F 0 ) exposure to triazophos with environmental dose could raise toxic effects on its offspring (F 1 ), which is mainly manifested by reduced heart rate, the accumulated number and individual size of offspring and decreased expression of genes related to molting and reproduction.
研究领域:
环境毒理学
·
水生生态学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
·
2023
·
IF 13.1
Oluwadamilola Pikuda,Eva Roubeau Dumont,Qiqing Chen,Jun-Ray Macairan,Stacey A. Robinson,Dimitrios Berk,Nathalie Tufenkji
We conducted a systematic review of 124 published articles that investigated the toxicity of microplastics and nanoplastics to Daphnia magna . This review summarizes studies assessing acute, chronic, and multigenerational impacts, as well as the effects observed via leached chemicals from plastics and the role of plastics as contaminant vectors. Overall, observed toxicity varies across different polymer types, and shapes. One of the most visible findings is that targeted research synthesis of the acute toxicity tests found more toxicity in smaller-sized particles. Most studies use spherical plastics that are commercially available, especially polystyrene, while the use of irregular-shaped and/or secondary plastics is still emerging. Also, there are still various confounding factors that make the comparison of the observed results difficult. Future studies should focus on irregular-shaped particles, and other polymer types, besides polystyrene. More research efforts are needed to understand the impacts of environmental factors and complex matrices.
研究领域:
生态毒理学
·
环境科学
✓ 已验证
DOI
高影响因子
Frontiers in Environmental Science
·
2022
·
IF 5.411
Yu Bo,Lyu Kai,Li Jiajia,Yang Zhou,Sun Yunfei
Nitrite and ammonia are two of the most common toxic nitrogenous pollutants in aquatic ecosystem, which can pose a serious threat to the health of aquatic organisms. Cladocerans, as an important part of freshwater ecosystem, will inevitably be harmed by these pollutants. To evaluate the combined toxic effects of these nitrogenous pollutants on cladocerans, we simulated 15 combinations of five nitrite concentrations (0, 0.5, 2, 4, 8 mg L−1) and three ammonia concentrations (0, 0.1, 1 mg L−1) to study the changes of life history traits of Daphnia pulex exposed to these combinations for 21 days. Results showed that under the combined stress of nitrite and ammonia, the survival time of D. pulex was shortened, the time to first batch of eggs and time to first brood were delayed, the body size and tail spine length at maturation were reduced, and the total offspring and the number of broods were decreased. There were some synergistically negative effects between the two nitrogenous pollutants. The presence of ammonia reduced the tolerance of D. pulex to nitrite, and vice versa. These findings provided new insights into the combined toxic effects of nitrite and ammonia on the life history traits of cladocerans, and were of great significance for understanding the population dynamics of specific species in cladocerans community under the condition of compound nitrogenous pollutants.
研究领域:
生态毒理学
·
环境科学
✓ 已验证
DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2020
·
IF 9.038
Wei Lin,Ruifen Jiang,Xiaoying Xiao,Jiayi Wu,Songbo Wei,Yan Liu,Derek C.G. Muir,Gangfeng Ouyang
Nanoplastics (NPs) are emerging pollutants which can adsorb large amounts of hydrophobic organic compounds (HOCs) and be ingested by aquatic organisms. NPs interact with dissolved organic matter (DOM) and result in significant impacts on the bioaccumulation of HOCs in the actual environment. For the first time, the joint effects of two complex matrices on the bioaccumulation of polycyclic aromatic hydrocarbons (PAHs) to Daphnia magna ( D. magna ) were studied by modeling calculation. The complex matrices, nano-sized polystyrene (PS) and/or humic acid (HA), were under environmentally realistic concentrations. A biodynamic model was modified and the uptake fluxes from all exposure pathways were quantified using the experimental data. A flux estimation showed that the bioaccumulation amounts at equilibrium were mostly dependent on dermal uptake (≥99.3 % of the total). The PS matrix would retard the intestinal uptake process in D. magna , especially for the less hydrophobic PAHs; while the HA or the HA-PS matrix would facilitate the mass transfer of PAHs from the matrix to lipids in the gut. Moreover, the biota matrix accumulation factor (BMAF) were calculated to verify the biodynamic model. This work is helpful to clarify the bioaccumulation effects of PAHs in complex environmental systems.
研究领域:
环境科学
·
生态毒理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2018
·
IF 6.434
Wei Lin,Ruifen Jiang,Yaxin Xiong,Jiayi Wu,Jianqiao Xu,Juan Zheng,Fang Zhu,Gangfeng Ouyang
It has been reported that nanoplastics (NP) could cause serious toxicity and accumulative effects on aquatic organisms as well as interact with organic pollutants and influence potential hazards when exposed to biota. The current study aimed to quantitatively investigate the combined acute toxic effect of polychlorinated biphenyls (PCBs) and nano-sized polystyrene (PS) plastic on aquatic organisms based on analyte speciation. First, the combined acute toxicity of PCB-18 and 100 nm PS to Daphnia magna ( D. magna ) in water was evaluated. Then, speciation analysis of the exposure system was conducted by measuring the sorption coefficients ( logK NP ) of PCBs to nano-sized PS (ranging from 5.28 to 6.56), which demonstrated the PS could substantially decrease the free concentrations of PCBs. The results showed that a low concentration of the PS could decrease the toxicity to D. magna ., which might be originated from the decreased free concentration of PCB-18. However, when the PS concentration was high enough, an opposite effect was observed because the PS dominated the lethality instead of PCB-18. The current study is helpful to clarify the PCB occurrence in ecosystems and provide an in-depth understanding of the eco-toxicological effects of nanoscale plastics.
研究领域:
环境科学
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生态毒理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF ENVIRONMENTAL MANAGEMENT
·
2023
·
IF 8.7
Lin Hou,Xiaowei Jin,Na Liu,Ying Luo,Jianhua Liao,Changsheng Guo,Jian Xu
Triadimefon is ubiquitous in various environmental media. Although toxicity of triadimefon to individual of aquatic organisms has been confirmed, its effect on organisms at population level remain poorly understood. In this study the long-term effect of triadimefon on individual and population of Daphnia magna were studied using multi-generational experiments and matrix model. Development and reproduction of three generations of F1 and F2 were significantly inhibited with the triadimefon concentration of 0.1 mg/L ( p < 0.01). Toxicity of triadimefon to the offspring was stronger than to the parent ( p < 0.05). When triadimefon concentration was higher than 0.1 mg/L, both population number and intrinsic rate of increase showed a decreasing trend with the increasing exposure concentration. Age structure of the population also tended to decline. Toxicity threshold derived on population-level was between mortality-based LC 50 and reproduction-based NOEC of Daphnia magna , and also between acute toxicity and chronic toxicity derived from species sensitivity distribution (SSD). The risk of population level derived from risk quotient was low for most areas, and the results derived from probability risk showed that the expected loss of intrinsic rate of increase of population was 0.0039 without considering other factors. Compared to the individual-level, the ecological risks at the population level were closer to the actual situation of the ecosystem response to the chemical pollution.
研究领域:
环境科学
·
毒理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
International Journal of Environmental Research and Public Health
·
2022
·Vol. 19
·期 15
·9382
·
IF 4.614
Wenxin Liu,Hong Zhang,Jiaqi Ding,Wanyu He,Lin Zhu,Jianfeng Feng
Organophosphate esters (OPEs) are widely used as an additive in flame retardants, plasticizers, lubricants, consumer chemicals, and foaming agents. They can accumulate in aquatic organisms from water (waterborne exposure) and food (dietary exposure). However, the bioaccumulation characteristics and relative importance of different exposure routes to the bioaccumulation of OPEs are relatively poorly understood. In this study,Daphnia magnawere exposed to fo typical OPEs (tris(2-chloroethyl) phosphate (TCEP), tris(1,3-dichloro-2-propyl) phosphate (TDCIPP), tris(2-butoxyethyl) phosphate (TBOEP), and triphenyl phosphate (TPHP)), and their toxicokinetics under waterborne and dietary exposure routes were analyzed. For the waterborne exposure route, the bioconcentration factors (BCFs) increased in the order of TBOEP, TCEP, TDCPP, and TPHP, which were consistent with their uptake rate constants. TPHP might have the most substantial accumulation potential while TBOEP may have the smallest potential. In dietary exposure, the depuration rate constants of four OPEs were different from those in the waterborne experiment, which may indicate other depuration mechanisms in two exposure routes. The biomagnification factors (BMFs) of fur OPEs were all below 1, suggesting trophic dilution in the transfer of four OPEs fromScenedesmus obliquustoD. magna. Except for TBOEP, the contributions of dietary exposure were generally lower than waterborne exposure inD. magnaunder two exposure concentrations. This study provides information on the bioaccumulation and contribution of OPEs inD. magnavia different exposure routes and highlights the importance of considering different exposure routes in assessing the risk of OPEs.
研究领域:
环境科学
·
生态毒理学
✓ 已验证
DOI
高影响因子
ENVIRONMENTAL POLLUTION
·
2015
·
IF 4.143
Xinghao Wang,Ruijuan Qu,Jiaoqin Liu,Zhongbo Wei,Liansheng Wang,Shaogui Yang,Qingguo Huang,Zunyao Wang
Experiments were conducted to investigate the effect of four different carbon nanotubes single- and multi-walled carbon nanotubes (SWCNTs and MWCNTs) and hydroxylated and carboxylated multi-walled carbon nanotubes (OH-MWCNTs and COOH-MWCNTs) on Cd toxicity to the aquatic organism Daphnia magna . The acute toxicity results indicated that all CNTs could enhance the toxicity of Cd to D. magna . Furthermore, the filtrate toxicity and adsorption tests showed that the toxicity-increasing effect of SWCNTs and MWCNTs in the overall system was mainly caused by catalysts impurities from the pristine CNTs, whereas the greater adsorption of Cd onto OH-MWCNTs (30.52 mg/g) and COOH-MWCNTs (24.93 mg/g) was the key factor contributing to the enhanced toxicity. This result raised a concern that the metal catalyst impurities, adsorption capacities, and accumulation of waterborne CNTs were responsible for the toxicity of Cd to aquatic organism.
研究领域:
环境科学
·
毒理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）