JOURNAL OF CHEMICAL THERMODYNAMICS
·
2023
·
IF 2.6
Pengshuai Zhang,Jixiu Deng,Xiaoyu Jiang,Liang Xu,Yu Huang,Han Sun,Mi Gao,Xianghan Wang,Yulong Gao,Kangning Fan,Lu Zhang,Shuoye Yang
In the present study, solubility of daminozide was determined in twelve neat solvents (N,N-Dimethylformamide (DMF), 2-methoxyethanol, N-Methyl-2-pyrrolidone (NMP), 2-ethoxyethanol, Acetonitrile (MeCN), 2-propoxyethanol, methanol, ethanol, n -propanol, i -propanol, n -pentanol, 2-butoxyethanol) by using the gravimetrical method under the pressure of 0.1 MPa and temperature from 283.15 to 323.15 K. The maximum solubility value (10 2 x 1 ) of daminozide was found in NMP at 323.15 K (10.04), while the minimum solubility value (10 2 x 1 ) of daminozide was found in n -pentanol at 283.15 K (0.0149). At the temperature of 298.15 K, the order of the experimental solubility values (100 x 1 ) of daminozide in twelve neat solvents was: NMP (5.523) > DMF (3.294) > methanol (1.395) > 2-methoxyethanol (0.7839) > ethanol (0.5515) > 2-ethoxyethanol (0.3816) > n -propanol (0.2175) > i -propanol (0.1099) > 2-propoxyethanol (0.1083) > 2-butoxyethanol (0.0632) > MeCN (0.0386) > n -pentanol (0.0344). Five models including van't Hoff model, Buchowski-Ksiazczak λh model, NRTL model, UNIQUAC model and Jouyban model were employed to correlate and analyze the experimental solubility of daminozide. Based on the principle of similar compatibility, the miscibility of daminozide in the selected solvents was discussed with the help of Hansen solubility parameters ( HSPs ). Finally, the apparent thermodynamic properties were investigated and results indicated that the dissolution mechanism of daminozide in all selected solvents was an entropy-driven and endothermic process.
研究领域:
化学
·
药学
✓ 已验证
产品关联
DOI
高影响因子
BIORESOURCE TECHNOLOGY
·
2014
·
IF 5.039
Yantao Wang,Ligang Wei,Kunlan Li,Yingchong Ma,Ningning Ma,Shan Ding,Linlin Wang,Deyang Zhao,Bing Yan,Wenying Wan,Qian Zhang,Xin Wang,Junmei Wang,Hui Li
Lignin dissolution in dialkylimidazolium-based ionic liquid (IL)–water mixtures (40 wt%–100 wt% IL content) at 60 °C was investigated. The IL content and type are found to considerably affect lignin solubility. For the IL–water mixtures except 1-butyl-3-methylimidazolium tetrafluoroborate ([C 4 C 1 im]BF 4 ), the maximum lignin solubility can be achieved at 70 wt% IL content. Lignin solubility in IL–water mixtures with different cations follows the order 1-butyl-3-methylimidazolium ([C 4 C 1 im] + ) > 1-hexyl-3-methylimidazolium ([C 6 C 1 im] + ) > 1-ethyl-3-methylimidazolium ([C 2 C 1 im] + ) > 1-octyl-3-methylimidazolium ([C 8 C 1 im] + ) > 1-butyl-3-ethylimidazolium ([C 4 C 2 im] + ) > 1-butyl-3-propylimidazolium ([C 4 C 3 im] + ). For IL mixtures with different anions, lignin solubility decreases in the following order: methanesulfonate (MeSO 3 − ) > acetate (MeCO 2 − ) > bromide (Br − ) > dibutylphosphate (DBP − ). Evaluation using the theory of Hansen solubility parameter (HSP) is consistent with the experimental results, suggesting that HSP can aid in finding the appropriate range of IL content for IL–water mixtures. However, HSP cannot be used to evaluate the effect of IL type on lignin solubility.
研究领域:
化学工程
·
材料科学
✓ 已验证
DOI
PubMed
高影响因子
AAPS PHARMSCITECH
·
2018
·Vol. 19
·期 5
·2288-2300
·
IF 2.666
Hu Beibei,Sun Wei,Yang Baixue,Li Heran,Zhou Liuchenzi,Li Sanming
Solvents, accounting the majority of the organogel system, have a tremendous impact on the characteristics of gels. To date, there is a large variety of organogel systems; relatively few have been investigated in the field of structure-solvent correlation. Here, a series of solvent parameters were applied to explore the role of solvent effect on network forming and gel property, intending to build the connection between the precise solvent parameter and gel property. Among the solvent parameters, Kamlet–Taft Parameters and Hansen solubility parameters can distinguish specific types of intermolecular interactions, which could correlate solvent parameter with the gel property. From an analysis of the morphologies obtained from POM and SEM, the gelator structure has an impact on its self-assembly. For possible conformations, the gelators were investigated through XRD. The investigation of solvent-property relationship will provide a theoretical basis for controllable drug delivery implants.
研究领域:
材料科学
·
药物递送
·
化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
·
2018
·
IF 0.824
Meng-Fei LAN,Ning AN,Ying ZHAO,Wei CAO,Heng LI,Lan ZHAO,Yong-Dong HUANG,Rong-Yue ZHANG
The macroporous microspheres were prepared through suspension polymerization based on a copolymer of glycidyl methacrylate and ethylene glycol dimethacrylate. The effect of porogen on the microspheres structure was evaluated in terms of pore size and surface area. Porogen contained dichloromethane ( δ = 9.7 (cal cm –3 ) 1/2 ) and N -octanol ( δ = 10.3 (cal cm –3 ) 1/2 ) which were correspond to a good and poor solvent, respectively. The solubility parameter of porogen was controlled in the range of 9.89–10.09 (cal cm –3 ) 1/2 . The pore size of microspheres increased with the increase of difference value of solubility parameter between the polymer and the porogen. On the contrary, the surface area of microspheres decreased. The anion exchange media was prepared through coupling poly(ethylene imine) in the microspheres and the proteins transport was determined by frontal analysis method. The macroporous microspheres with 257 nm pore size could still afford a high proteins capacity (45.1 mg mL –1 ). These macroporous supports showed great potential in rapid separation of proteins.
研究领域:
生物技术
·
材料科学
·
化学工程
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）