MOLECULES
·
2021
·Vol. 26
·期 7
·1925
·
IF 4.412
Xiao-Qiang Jiang,Shi-Quan Chen,Yan-Fei Liu,Xin-Guang Pan,Dan Chen,Shi-Fan Wang
Solvothermal synthesis of multiple dihydropyrimidinones at a time has been developed in inexpensive and green bio-based solvent lactic acid without any additional catalysts or additives. By this method, thirty new dihydropyrimidinone derivatives were synthesized in two batches and characterized. All of the compounds were screened by Eg5 motor protein ATPase assay, and the positive compounds were tested against the Caco-2 cell line, HeLa cell line, L929 cell line and T24 cell line in vitro. Among them, compound C9 exhibited the best inhibitory activity against motor protein ATPase with an IC50value of 30.25 μM and significant cytotoxic activity in the micromolar range against the cells above. The Lineweaver–Burk plot revealed that compound C9 was a mixed-type Eg5 inhibitor. A molecular modeling study using the Discovery Studio program was performed, where compound C9 exhibited good binding interaction with Eg5 motor protein ATPase, and this was consistent with the attained experimental results.
研究领域:
药物化学
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肿瘤学
·
合成化学
✓ 已验证
DOI
高影响因子
Journal of Materials Chemistry C
·
2015
·Vol. 3
·期 46
·12077-12082
·
IF 4.696
Chao Pang,Ling Gao,Anurag Chaturvedi,Ningzhong Bao,Kazumichi Yanagisawa,Liming Shen,Arunava Gupta
Magnetic spinel CdCr2S4 nanocrystals have been synthesized using a high-temperature solvothermal method. The synthesis process involves the reaction of excess 1-dodecanethiol (1-DDT) with CdCl2 and CrCl3·6H2O in 1-octadecene (ODE) solution carried out in a sealed titanium alloy autoclave. Nearly monodisperse spherical CdCr2S4 nanocrystals with an average size of 8.0 ± 1.5 nm are obtained. X-ray diffraction patterns confirm formation of the pure spinel phase without any impurities. Magnetic measurements indicate a Curie temperature (Tc) of ∼76 K for the synthesized CdCr2S4 nanocrystals, which are ferromagnetic at lower temperatures with a saturation magnetization value of 19 emu g−1 at 5 K. The magnetic entropy change ΔSm, evaluated from isothermal magnetic measurements, exhibits a maximum around 82 K, with a value of −ΔSm = 0.86 J kg−1 K−1 at Hmax = 5 T. ΔSm spans a broad temperature range, with a full width at half maximum of ∼88 K in the magnetic field range of 0–5 T, which is attractive for magnetic refrigeration applications in the liquid nitrogen temperature range.
研究领域:
材料科学
·
磁学
✓ 已验证
DOI
高影响因子
MATERIALS LETTERS
·
2015
·
IF 2.489
Jingzhong Zhao,Weiqiang Xing,Yang Li,Kathy Lu
Oxygen-deficient anatase TiO 2 sheets with dominant (001) facets are becoming a hot research topic due to their promising high activity in heterogeneous reactions . In this work, a series of (001) facets dominated TiO 2 with distributed oxygen vacancies and Ti 3+ was prepared by a simple hydrothermal method with the TiB 2 as a precursor. The as-prepared powders were characterized by X-ray diffraction (XRD), Scanning electron microscope (SEM), Transmission Electron Microscope (TEM), X-ray photoelectron spectroscopy (XPS) and UV–visible diffuse reflectance spectroscopy (UV–vis). The results show that the particle size of as-prepared TiO 2 increases and its band gap narrows with the hydrothermal temperature increasing from 140 °C to 180 °C. Besides, oxygen vacancies and Ti 3+ are generated during the TiB 2 hydrolysis, which leads to new absorption spectrum in the visible light region. Photocatalytic test shows that sample prepared at 180 °C presents the highest degradation efficiency.
研究领域:
材料科学
·
光催化
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纳米材料
·
表面化学
·
半导体材料
✓ 已验证
DOI
高影响因子
RSC Advances
·
2013
·Vol. 4
·期 2
·954-958
·
IF 2.562
Guihua Li,Xuzhong Cui,Cuiying Tan,Nan Lin
Uniform and polycrystalline tellurium nanoplates with a thickness of 100–300 nm can be rapidly synthesized by a simple solvothermal method in mixtures of water and ethanediamine at 180 °C with the assistance of glucose. By adjusting the concentration of glucose, tellurium microrods and nanoplates can be prepared. Based on the electron microscope observations, a possible mechanism involved the self-assembly process and dissolution–recrystallization mechanism is proposed for explaining the formation of polycrystalline tellurium nanoplates and their transformation into single crystalline nanorods. Furthermore, the Raman scattering measurement for the different morphologies is conducted, and the polycrystalline nanoplates present the stronger Raman scattering spectrum.
研究领域:
材料科学
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纳米技术
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无机化学
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凝聚态物理
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光谱学
✓ 已验证
DOI
高影响因子
RESEARCH ON CHEMICAL INTERMEDIATES
·
2022
·Vol. 48
·期 10
·4105-4118
·
IF 3.134
Tang Wanjun,Liu Yunyi,Ding Shuang,Zhao Dongmei,Li Tingcheng,Xie Guangyong
MoV 2 O 8 micro-cuboids were environment-friendly prepared via a facile one-step solvothermal route followed by thermal treatment with vanadium pentoxide and ammonium molybdate as raw materials without using harmful solvents or surfactants. Characterization by XRD, FTIR, XPS, SEM and TEM showed that MoV 2 O 8 formed a layered structure by the stacking of nanosheets and assumed a micro-cuboid shape with a thickness of 150∓30 nm, a width of 350∓110 nm and a length of 680∓18 nm. For the first time, the catalytic properties of MoV 2 O 8 micro-cuboids were investigated for the gas-phase ammoxidation of p -chlorotoluene (PCT) to p -chlorobenzonitrile (PCBN). The as-prepared catalyst exhibited high activity and selectivity in the ammoxidation of PCT to PCBN, with a near 100% conversion and 83.6% yield.
Graphical abstract
研究领域:
材料化学
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催化化学
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纳米材料
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绿色合成
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有机反应工程
✓ 已验证
DOI
高影响因子
JOURNAL OF SOLID STATE ELECTROCHEMISTRY
·
2023
·Vol. 29
·期 1
·51-59
·
IF 2.5
Zhang Wenkui,Bao Jian,Lu Chengwei,Zhou Xiaozheng,Xia Xinhui,Zhang Jun,He Xinping,Gan Yongping,Huang Hui,Wang Chen,Wan Wangjun,Fang Ruyi,Xia Yang
TiNb 2 O 7 (TNO) has been regarded as a promising anode material for high-power lithium–ion batteries due to its high theoretical capacity and work voltage (387.6 mA h g −1 , 1.6 V vs. Li + /Li). Herein, a series of microspherical TNO anode materials are synthesized by a facile solvothermal method, and the effect of solvothermal time on the microstructure and electrochemical performance is investigated. Specifically, when the solvothermal time is 12 h, the TNO microsphere (TNO-12) exhibits higher specific surface area and more reasonable pore size distribution. As a result, TNO-12 anode delivers a high reversible discharge capacity of 299.87 mA h g −1 with a superior initial coulombic efficiency above 98.5%, excellent cycling capacity retention of 80.15% after 100 cycles at 0.5 C (150 mA g −1 ), and good rate performance at 0.1–2 C. Most importantly, the full cell constructed with TNO anode and commercial oxide cathode (LiNi 0.6 Mn 0.4 O 2 /LiMn 2 O 4 with a mass ratio of 85: 15) exhibits excellent cycling stability at high current densities (79.14% after 100 cycles at 0.5 C). This study optimizes the synthesis process for high-performance microspherical TNOs, providing new insights for the next generation of commercial anodes.
研究领域:
材料科学
·
电化学
·
纳米技术
·
储能
✓ 已验证
DOI
高影响因子
JOURNAL OF ELECTRONIC MATERIALS
·
2024
·Vol. 53
·期 5
·2656-2665
·
IF 2.2
Xiong Shanxin,Zhang Yukun,Zhang Wei,Yang Nana,Lv Fengyan,Guo Jingru,Cui Xin,Fang Ke,Chen Min,Wang Chenxu,Hua Chunxia,Zhang Runlan,Chu Jia,Xu Jianwei
Covalent organic frameworks (COFs) with reversible redox units and a conjugated molecular skeleton possess novel photoelectrochemical properties. In this work, tris(4-aminophenyl)amine and 4,4-biphenyldiformaldehyde were chosen to synthesize TABP-COF electrochromic film with triphenylamine (TPA) active unit by a solvothermal method in a Teflon-lined reactor. The growth process and reaction time optimization of the TABP-COF were studied. TABP-COF shows a self-assembly growth process from an array of nanosheets to nanospheres. Owing to the redox characteristics of TPA, the TABP-COF film exhibits reversible electrochromic behavior. With a solvothermal reaction time of 72 h, the TABP-COF-3 film exhibits the best electrochromic properties, including contrast of 0.483 and response time of 7.3 s/13.6 s. Considering the abundance of redox-active units that can be chosen, COF materials with different redox units and color changes can be designed for a variety of applications in the field of electrochromic materials.
研究领域:
材料科学
·
电化学
·
纳米技术
·
有机化学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）