Journal of Materials Chemistry B
·
2022
·Vol. 10
·期 6
·915-926
·
IF 7.571
Liwei Zhang,Yajie Zhang,Fanshu Ma,Xingzhu Liu,Yangzhong Liu,Yi Cao,Renjun Pei
Hydrogel-based wound dressings with tissue adhesion abilities are widely used for wound closure. However, currently developed hydrogel adhesives are still poor at continuing to seal wounds while bleeding is ongoing. Herein, we demonstrate an antibacterial and hemostatic hydrogel adhesive with low-swelling properties and toughness for wound healing. The hydrogel was composed of Pluronic F127 diacrylate, quaternized chitosan diacrylate, silk fibroin, and tannic acid, and it was not only able to maintain good tissue adhesion abilities in a moist environment but it also showed guaranteed tissue adhesion and mechanical strength after absorbing water due to its low-swelling and toughness properties. Furthermore, in vitro and in vivo tests demonstrated that the hydrogel also had antibacterial, antioxidant, and hemostatic properties, which could promote tissue regeneration. All these findings demonstrate that this hydrogel with multifunctional properties is a promising material for clinical wound healing applications.
研究领域:
生物医学工程
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材料科学
·
组织工程
✓ 已验证
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Xinyu Qian,Yuqian Guo,Yumeng Zhao,Leilei Hou,Yun Cheng,Linghua Chen,Shuo Yang,Hongjie Zhang
The swelling performance of the biological macromolecules of cellulose in aqueous N -methyl-morpholine-N-oxide (NMMO) solution is a critical factor in improving cellulose dissolution efficiency during lyocell process. We focused on the diffusion behavior of NMMO solvent during cellulose swelling and dissolution process using a novel centrifugation method, clarifying the relationship between NMMO retention value, fiber structural properties, and dissolution efficiency. An effective quantitative index for evaluating the swelling performances of cellulose is NMMO-retention, which was defined by investigating the removal of aqueous NMMO solution from swollen cellulose fibers using centrifugal method. Based on the variation of NMMO-retention and centrifugal force at 500 and 3000 g , the removal process was divided into three stages: rapid removal stage (0–500 g), slow removal stage (500–3000 g), and residual removal stage (3000–5000 g). In addition, the relationship between fiber structural properties (fiber length, width, fine content, and specific surface area) and swelling-dissolution performance was established. The results indicate that the NMMO-retention of cellulose is a comprehensive reflection of the fiber structural characteristics, and it shows an obvious negative correlation with the dissolution time of cellulose. The cellulose that shows the highest NMMO-retention (729.5 %) after swelling has the shortest dissolution time (20 min) during subsequent dissolution.
研究领域:
材料科学
·
生物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2022
·
IF 9.136
Hongli Zhang,Yiling Zheng,Hongwei Zhou,Shilin Zhu,Jie Yang
Two-dimensional (2D) nanomaterial-based membranes display attractive properties in molecular separation and transport, which holds their great promise for a host of applications. However, notorious swelling problem of 2D membranes result in unsatisfactory molecular/ions sieving performance, and the enhancement of structural stability for 2D membranes in aqueous solution is still challenging. Herein, we demonstrate how to efficiently stabilize the Ti 3 C 2 T x MXene laminar architecture by the insertion of flexible and hydrophilic carboxylated cellulose nanofibers (CNFs). The importing of CNFs not only acted as a bridge to combine the adjacent 2D Ti 3 C 2 T x sheets and enhance mechanical strength, but also assumed the role of pillar to fix the interlayer distance effectively and improve the anti-swelling properties of Ti 3 C 2 T x membrane. Moreover, the intercalation of nanocelluloses into the interlayer of delaminated Ti 3 C 2 T x is able to distinctly increase the interlayer spacing and create more open gaps for fast and selective molecular transport. When applied in antibiotics separative filtration process, the resultant membrane exhibits outperformed anti-swelling properties in water environment up to 76 h and simultaneously possesses satisfactorily high selectivity of antibiotics (∼99.0 % for azithromycin) with unprecedentedly high pure water permeance (∼26.0 L m −2 h −1 bar −1 ). Such 2D membranes can be easily fabricated by a facile and patternable vacuum-assisted filtration and nanocellulose induced self-assembly strategy, which holds great potential for their scalability that are applicable to many applications such as seawater desalination, industrial wastewater treatment and remediation of aquatic environment.
研究领域:
材料科学
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环境科学
·
化学工程
✓ 已验证
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2019
·
IF 4.784
Xiaotong Xiang,Guoqi Chen,Kai Chen,Xiancai Jiang,Linxi Hou
Facile preparation of super tough hydrogels with low temperature tolerance and anti-swelling property is still a challenging task for researchers. Meanwhile, the vast majority of tough hydrogels were obtained though chemical crosslinking and complicated synthesis or processing method accompanying a large number of harmful chemical reagents. Herein, the super tough chitosan/poly(vinyl alcohol) (CS/PVA) hydrogels (the maximum compressive strength of 18.97 MPa at a strain of 80% and the maximum tensile strength of 4.02 MPa at a strain of 406.4%) were successfully prepared via a simple post-treatment method. CS/PVA hydrogels were firstly prepared by freezing-thawing process and then soaking in saturated sodium chloride aqueous solution. The resultant hydrogels possess excellent swelling resistance and low temperature tolerance. This work shows that the post-treatment of immersing in saline solution is a feasible way to prepare super tough hydrogels with low temperature tolerance and anti-swelling property. This also would enlarge the application areas of CS.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
RSC Advances
·
2024
·Vol. 14
·期 5
·2993-2999
·
IF 3.9
Bin Li,Haiying Liu,Mengjing Zhou,Aolin Wu,Wenrui Hao,YaJun Jiang,Zhigang Hu
Deep eutectic solvents (DES) were prepared using urea (U) and acrylamide (AM) as hydrogen bond donors (HBD) and choline chloride (ChCl) as hydrogen bond acceptor (HBA), and polyethylene glycol (PEG) was selected as a filler and uniformly dispersed in DES to prepare PEG/P(U-AM-ChCl) composite hydrogels by light polymerization. The composite hydrogels were characterized by scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR). The effects of the content of PEG on the swelling properties, mechanical properties and fatigue resistance of the composite hydrogels were investigated. The results showed that the compressive strength and fatigue strength of the composite hydrogels were gradually enhanced with the increase of the PEG content in the composite hydrogels, in which the maximum compressive strength of the hydrogels with 1 wt% PEG added was increased by 1.86 times. The composite hydrogel had excellent swelling properties, and the equilibrium swelling degree of the hydrogel with 1 wt% PEG added reached 10.15. Meanwhile, the PEG/P(U-AM-ChCl) composite hydrogel had excellent self-healing properties, and the self-healing rate of the composite hydrogel with a PFG content of 1 wt% could reach 91.93% after 48 hours of healing. This study provides a convenient and efficient method to prepare composite hydrogels with superior swelling properties and self-healing properties.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2019
·
IF 7.015
Shuhao Wang,Kaifeng Gu,Jian Wang,Yong Zhou,Congjie Gao
Preparation of novel swelling resistance membrane by interpenetrating an immiscible flexible polyisobutylene (PIB) polymer into a rigid polyamide (PA) network by interfacial polymerization. Due to the force interlocking of flexible PIB, polyamide network has high strength and excellent resistance to methanol. The PA layer was characterized by mechanical strength , attenuated total reflection fourier transforms infrared spectroscopy (ATR-FTIR), small angle X-ray scattering (SAXS), contact angle, field emission scanning electron microscope (FE-SEM) and atomic force microscope (AFM). RO membrane performances were evaluated based on small molecule alcohol (methanol and ethanol) solution of Safranin O. The results show that the flexible PIB interpenetrates well in the rigid polyamide network and improves mechanical strength and swelling resistance. With an increasing concentration of PIB from 0% to 0.30% in the organic phase during the fabrication, the mechanical strength of the PA layer becomes 2.8 times that of the original, and the rejection of Safranin O increased from 95.43% to 99.43%, and the permeability coefficient ( B s ) decreased from 5.22 to 0.47.
研究领域:
材料科学
·
化学工程
·
膜技术
✓ 已验证
产品关联
DOI
高影响因子
CLAYS AND CLAY MINERALS
·
2021
·Vol. 69
·期 6
·759-771
·
IF 1.609
Yu Wei Hua,Liu Jia Hui,Wang Min,Li Na,Zhang Jun Rui,Huang Tian Hao,Zhou Chun Hui
Organo-montmorillonite (OMnt) has wide applications in paints, clay-polymer nanocomposites, biomaterials, etc. In most cases, the dispersibility and swellability of OMnt dictate the performance of OMnt in the target products. Previous studies have revealed that the properties can be improved when multiple organic species are co-introduced into the interlayer space of montmorillonite (Mnt). In the present study, single surfactant erucylamide (EA), dual-surfactants cetyltrimethyl ammonium bromide (CTAB) and octadecyltrimethyl ammonium chloride (OTAC), and ternary-surfactants EA, CTAB, and OTAC were co-introduced into Mnt by solution intercalation. The resulting OMnts were characterized by powder X-ray diffraction (XRD), Fourier-transform infrared (FTIR) spectroscopy, thermogravimetry-differential thermogravimetry (TG-DTG), water contact-angle tests, scanning electronic microscopy (SEM), laser particle-size analysis, and swelling indices. Mnt co-modified by ternary CTAB, OTAC, and EA led to a large d 001 value (4.20 nm), surface hydrophobicity with a contact angle of 95.6°, swellability (50 mL/g) with small average particle sizes (2.1−2.8 μm) in xylene, and >99% of the OMnt particles were kept as <5 μm in deionized water. The formation of EA-modified-Mnt was proposed according to hydrophobic affinity, hydrogen bonding, and van der Waals forces. The nanoplatelets of the CTA + , OTA + , and EA co-modified OMnts in xylene were assembled into a house-of-cards structure by face-to-edge and edge-to-edge associations. The electrostatic attractions, electrostatic and steric repulsions, and hydrophobic interactions were responsible for the good dispersibility of OMnt in xylene. The ternary surfactant co-modified OMnt with high dispersion and swellability will make OMnt better suited for real-world applications.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Yong Deng,Panpan Li,Yudong Lian,Zhaoguang Nie,Quan Ji,Xiaomei Ma
The rising energy and environmental crisis brought by extensive usage of disposable synthetic plastic packaging necessitates the pursuit of ecofriendly packaging materials. Herein, a novel type of biofilms from exopolysaccharide gellan gum (GG) were developed through successive sol-gel transition, hydroalcoholic pretreatment and ionic anchoring before air-drying. Universal electronic testing machine, gravimetry, contact angle meter and UV–visible spectrophotometer were employed to investigate the mechanics, swelling-resistance, surface hydrophobicity and barrier property. The results indicate hydroalcoholic pretreatment ameliorates the toughness of GG films, with the breakage elongation and tensile toughness reaching ~17 % and 9.44 MJ/m 3 . Metal-ion anchoring bestows swelling-resistance and surface hydrophobicity to GG films. The equilibrium swelling ratio after Fe 3+ -anchoring dropped to ~150 % in water, in stark contrast with the measurable swelling ratio of those unanchored beyond 2700 % which were followed by loss of dimensional integrity. The surface hydrophobicity is improved significantly with the water contact angle enlarged from 48° to 77° after Fe 3+ -anchoring. Metal-ion anchoring also improves the water vapor barrier performance, and notably Cu 2+ /Fe 3+ -anchoring endows UV light-shielding ability to GG films. The prominent performance along with the environmental friendliness of GG is conducive for future application in single-use packaging materials.
研究领域:
材料科学
·
环境科学
·
食品科学
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2020
·
IF 7.183
Yanqing Xu,Suyang Yu,Guibin Peng,Arcadio Sotto,Huimin Ruan,Jiangnan Shen,Congjie Gao
Organic solvent nanofiltration (OSN) membranes have gained increasing attention for their wide applications in organic phase system. However, the fabrication method rather than the swelling behavior receives more attention during the OSN testing. In this work, a thin-film composite membrane with an internal cross-linking network by reacting 4,4-bipyridine with brominated poly (2,6-dimethyl-1, 4-phenylene oxide) (BPPO) has been prepared for organic solvent nanofiltration (OSN). The bipyridine groups substituted on the polyphenylene oxide polymer backbone act as cross-linkers and cationic channels for remarkable chemical stability and high solvent permeability. The permeability of the cross-linked BPPO (CBPPO) thin-film membranes exhibited high related to the viscosity and solubility parameter of solvents. The stability of CBPPO membrane was studied via various organic solvent immersing experiments. The result demonstrated that the composite membrane swelling changed to an extent of no more than 2.01%. It can be attributed to the low conformational flexibility of polymer chains with a high crosslinking degree. The ethanol permeation and dye rejection were compared before and after soaking. The calculation of the MWCO and membrane potential of modified CBPPO membranes showed that the swelling behavior of the CBPPO composite membranes is mainly affected by the membrane charge densities rather than the pore size.
研究领域:
材料科学
·
膜技术
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
QUIMICA NOVA
·
2022
·Vol. 45
·期 2
·145-151
·
IF 1.145
Sun Fei,Feng Chao,Wang Yang,Yang Xue,Zhao Hong
The fluorescent microspheres are prepared by the swelling-evaporation method. The optimal swelling conditions are obtained by researching related factors, such as types and dosages of swelling agent, dosages of fluorescent substance, swelling time and swelling temperature. Considering that the structure of microspheres can influence the swelling properties, the paper mainly focuses on the effect of molecular weight and surface carboxyl group content of polystyrene microspheres on swelling properties. When the molecular weight of microspheres is 75276 g mol-1, the density of carboxyl group on their surface is 6.94×10-4 mol g-1, and the doping amount of europium complex reaches the maximum of 24.9 mg g-1 with the strongest fluorescence intensity. Meanwhile, the as-prepared fluorescent microspheres have high monodispersity, uniform particles size and high thermal stability (the decomposition temperature is 385oC), which sets up the good foundation for biomolecule detection. So, this work provides a significant experience for the preparation of fluorescent microspheres.
研究领域:
材料科学
·
生物医学
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2022
·
IF 8.025
Zhijie Zhao,Xuzhe Qin,Lilong Cao,Junjie Li,Yuping Wei
Existing anti-swelling hydrogels with poor mechanical strength restrict their underwater human monitoring as wearable electronic sensing equipment. Herein, a nonswelling double network (DN) hydrogel with strong self-recoverability (97.22%) was developed by adding chitosan (CS) to poly(acrylic acid-2-methoxyethyl acrylate)-Fe 3+ [P(AA-MEA)-Fe] network. Owing to the introduction of CS, the hydrogel displayed excellent nonswelling properties under aqueous solutions (pH = 1, 4 and 7), physiological saline, seawater, dodecane, n-hexane and chloroform. Besides, CS improved mechanical properties of hydrogel through non-covalent network (large stretchability of 1199%, tensile strength of 0.462 MPa and toughness of 2.01 MJ/m 3 ). Surprisingly, the hydrogel still reached the extensibility (1072%) and tensile stress (0.467 MPa) even after immersing in water for 7 days. Fabricating hydrogel as flexible strain sensor, periodic real-time signals of human movements (e.g., joint actions and electronic skin touching) were accurately monitored under the water and seawater. The nonswelling P(AA-MEA)-CS-Fe hydrogel shows huge potential in underwater sensing.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2023
·
IF 9.5
Yongqi Yang,Chunyang Lv,Chang Tan,Jingfang Li,Xin Wang
Recent years have witnessed the development of flexible electronic materials. Flexible electronic devices based on hydrogels are promising but face the limitations of having no resistance to swelling and a lack of functional integration. Herein, we fabricated a hydrogel using a solvent replacement strategy and explored it as a flexible electronic material. This hydrogel was obtained by polymerizing 2-hydroxyethyl methacrylate (HEMA) in ethylene glycol and then immersing it in water. The synergistic effect of hydrogen bonding and hydrophobic interactions endows this hydrogel with anti-swelling properties in water, and it also exhibits enhanced mechanical properties and outstanding self-bonding properties. Moreover, the modulus of the hydrogel is tissue-adaptable. These properties allowed the hydrogel to be simply assembled with a liquid metal (LM) to create a series of structurally complex and functionally integrated flexible sensors. The hydrogel was used to assemble resistive and capacitive sensors to sense one-, two-, and three-dimensional strains and finger touches by employing specific structural designs. In addition, a multifunctional flexible sensor integrating strain sensing, temperature sensing, and conductance sensing was assembled via simple multilayer stacking to enable the simultaneous monitoring of underwater motion, water temperature, and water quality. This work demonstrates a simple strategy for assembling functionally integrated flexible electronics, which should open opportunities in next-generation electronic skins and hydrogel machines for various applications, especially underwater applications.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）