Nanomaterials
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2019
·Vol. 9
·期 3
·355
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IF 4.034
Luqiang Huang,Changji Wu,Lijuan Xie,Xue Yuan,Xinyu Wei,Qun Huang,Youqiang Chen,Yudong Lu
Nanocellulose is an abundant green resource that, owing to the larger surface area, length, and diameter of the fibers, can be used as a framework for loading Ag nanoparticles and serve as substrate for surface enhancement Raman scattering (SERS). These properties would cause the hydroxyl groups on the surface to adsorb the Ag ions and reduce them to Ag seed to form a load fulcrum. This paper presents a convenient and environmentally friendly method for the fabrication of silver-nanocellulose composites (NCF-Ag). A commonly used pesticide, carbendazim (CBZ), was used as a SERS probe to evaluate the properties of NCF-Ag. The results showed that NCF-Ag possesses good homogeneity, reproducibility, and stability. Additionally, CBZ was found to have a low limit of detection (LOD), i.e., 1.0 × 10−8M, which indicates the possibility for trace analysis. Furthermore, it presents good linearity withR2= 0.98 at 1007 and 1270 cm−1in the range from 10−4~10−7M CBZ.Keywords:nanocellulose;surface enhancement Raman scattering (SERS);carbendazim;Ag nanoparticle
研究领域:
材料科学
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环境科学
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分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2019
·
IF 2.931
Lantian Su,Song Wang,Lumei Wang,Zhiyu Yan,Haoyang Yi,Dongwei Zhang,Guoqing Shen,Yun Ma
This paper proposes a fluorescent aptasensor for the detection of carbendazim (CBZ) in aqueous solution using CBZ-specific aptamer as sensing probe, gold nanoparticles (AuNPs) and Rhodamine B (RhoB) as indicator, respectively. In the absence of CBZ, CBZ aptamer could wrap AuNPs and maintained it dispersed in NaCl solution basically. Contrarily, the aptamer could specifically combine with CBZ and form a stable aptamer-CBZ complex, leaving AuNPs exposed to be aggregated by NaCl solution. The dispersed AuNPs could efficiently quench the fluorescence of RhoB, but those aggregated AuNPs have poor capability to impair the fluorescent indicator . Thus, the concentration of CBZ could be detected quantitatively through the distinction of the fluorescence intensity . This convenient fluorescent assay for CBZ had a wide linear range from 2.33 to 800 nM and a 2.33 nM limit of detection (LOD). Furthermore, it had high selectivity over pesticides, antibiotics, metal ions and other disrupting chemicals. As for application, the method could determine CBZ in water samples with recoveries in the range of 96.3–111.2%. This fluorescent aptasensor possessed great potential application for CBZ detection in actual aquatic environment.
研究领域:
分析化学
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环境科学
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纳米技术
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DOI
PubMed
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2025
·
IF 4
Zixing Wang,Yuxin Fan,Hong Chen,Xiang Chen,Dexuan Cai,Xihao Tang,Shengrun Zheng,Jun Fan,Songliang Cai,Weiguang Zhang
The development of novel chiral stationary phases (CSPs) based on spherical covalent organic frameworks (SCOFs) holds great importance in the field of chiral chromatographic separation. Herein, SCOF-1∼SCOF-4 were synthesized using 1,3,5-tris(4-aminophenyl)benzene (TAPB) as the connecting node and 2,5-dihydroxyterephthalaldehyde (DHTA) with 2,5-dimethoxyterephthalaldehyde (DMTA) as linkers, while controlling the ratio of two linkers. Subsequently, SCOF-3 containing phenolic hydroxyl groups was post-modified by 10-camphorsulfonyl chloride, yielding a derivative SCOF-5 with camphorsulfonyl groups. Besides, a vinyl-functionalized SCOF-6 was synthesized via the reaction of TAPB with 2,5-divinylterephthalaldehyde (DVTA). These SCOFs were then utilized as matrices to coat with the chiral selector cellulose-tris (3,5-dimethylphenylcarbamate) (CDMPC), resulting in the fabrication of six SCOFs@CDMPC CSPs. Their applications in high-performance liquid chromatography (HPLC) for chiral separations were systematically investigated. The results demonstrated that the chiral resolution performances of these CSPs varied depending on the SCOF matrices with different side chains, primarily due to their distinct zeta potentials. As the zeta potentials of the SCOFs matrices increased, the chiral separation capabilities of SCOFs@CDMPC CSPs improved sequentially. Notably, the SCOF-6@CDMPC CSP, prepared from SCOF-6 with the highest zeta potential, exhibited superior chiral separation performance, achieving efficient resolution of chiral compounds including metalaxyl, triticonazole, trans -stilbene oxide and 1-(1-naphthyl)ethanol with highest resolution up to 10.14. This work not only validates the potential of SCOFs as matrices for fabrication of new CSPs but also reveals that the zeta potential of SCOFs matrices is a critical factor influencing their chiral separation performances. These findings provide new insights for the design of advanced SCOFs-based CSPs.
研究领域:
化学
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材料科学
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分析化学
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产品关联
DOI
PubMed
高影响因子
TOXICOLOGY IN VITRO
·
2023
·
IF 3.2
Jing Nie,Jiabei Zhou,Yi Shen,Ruimiao Lin,Haihong Hu,Kui Zeng,Huichang Bi,Min Huang,Lushan Yu,Su Zeng,Jing Miao
The widespread use of triazole fungicides in agricultural production poses a potential risk to human health. This study investigates the interaction of five triazole fungicides, i.e., tebuconazole, triticonazole, hexaconazole, penconazole, and uniconazole with human renal transporters, including OAT1, OAT3, OCT2, OCTN1, OCTN2, MATE1, MATE2-K, MRP2, MDR1, and BCRP, using transgenic cell models. For uptake transporters, triticonazole was the substrate of OAT1 and OAT3 and the inhibitor of OCT2. Tebuconazole and penconazole inhibited OCTN2 (100 μM), while tebuconazole, triticonazole, hexaconazole, penconazole, and uniconazole inhibited MATE1 (100 μM). Tebuconazole and hexaconazole inhibited MATE2-K (100 μM). All five triazole fungicides were not substrates or strong inhibitors of MRP2, MDR1, and BCRP efflux transporters. Penconazole inhibited OCT2 with IC 50 = 1.12 μM. Penconazole and uniconazole inhibited MATE1 with IC 50 = 0.94 μM and 0.87 μM. Tebuconazole and hexaconazole inhibited MATE2-K with IC 50 = 0.96 μM and 1.04 μM, indicating that triazole fungicides may inhibit renal drug transporter activity at low concentrations. Triticonazole was transported by OAT1 and OAT3, and the K m values of triticonazole were 5.81 ± 1.75 and 47.35 ± 14.27, respectively. Tebuconazole and uniconazole were transported by OAT3, and the K m values of tebuconazole and uniconazole were 30.28 ± 7.18 and 87.61 ± 31.70, respectively, which may induce nephrotoxicity.
研究领域:
药理学
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毒理学
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分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
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