Bioactive Materials
·
2023
·
IF 18.9
Bowen Zheng,Peng Zhang,Qijun Lv,Tao Wu,Yadong Liu,Junjie Tang,Yanping Ma,Lili Cheng,Langtao Xu,Yizhen Wang,Yifan Xue,Jie Liu,Jie Ren
Image-guided thermal ablation (TA), which is less invasive, has been widely applied for treating various kinds of tumors. However, TA still poses the potential risk of thermal damage to sensitive tissue nearby. Therefore, an adjunctive thermoprotective hydrodissection technique with constant injection of 5% glucose (5% Glu) has currently been adopted for clinical application, but this may be hazardous to humans. In this study, a multifunctional hyaluronic acid-based hydrogel (HA-Dc) was developed for hydrodissection. Compared with 5% Glu (the most clinically used solution) and the previously reported F127 hydrogel, the HA-Dc hydrogel was studied in vitro in a porcine liver model and in vivo in a rabbit model and showed good injectability and better tissue retention, stability, and thermoprotective properties throughout the TA procedure. Furthermore, in the preclinical evaluation in a Macaca fascicularis (M. fascicularis) model, HA-Dc showed excellent performance in terms of stricter neuroprotection compared with 5% Glu. In addition, the HA-Dc hydrogel with good biocompatibility and controllable degradation behavior in vivo could be a promising platform for thermal protection during clinical TA procedures.
研究领域:
医学工程
·
生物材料学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CERAMICS INTERNATIONAL
·
2025
·
IF 5.6
Hanqi Qian,Yue Yao,Qingyuan Cao,Tao Liu,Nan Li,Yudong Huang,Regina Maratovna Islamova,Bo Jiang
Developing coating materials, which are thermally insulating and high-strength support in extreme environments, is a hot spot for the thermal protection of aerospace. However, the lack of stable ceramic construction after prolonged thermal attack creates a risk of mechanical performance degradation. Herein, a silicon-based porous thermal protection composite was proposed by enveloping an innovative silicone resin on melamine frame. The thermostability of silicone resin was significantly improved by just 2 wt% addition of a multifunctional silane monomer, due to the incorporated diphenylamine and its derived quinonimine structure. Meanwhile, the uniform distribution of ammonium polyphosphate (APP) in the system effectively filled defects and cracks during pyrolysis. These facilitated the formation of an ordered porous polymer-derived ceramic framework under high temperature, thus significantly enhancing the material's mechanical strength (1200 °C, 3.39 MPa) and thermal insulation. Notably, even when subjected to prolonged high-temperature flame impact, the 3 mm-thick quinonimine-incorporated coating maintained its intact structure and preserved a backside temperature 77 °C lower than that of traditional silicone/melamine coating. This work provides a strategy for developing thermal protection composites that exhibit machinability, high strength, and superior thermal insulation performance in extreme environments.
研究领域:
材料科学
·
航空航天工程
✓ 已验证
产品关联
DOI
高影响因子
Food & Function
·
2018
·Vol. 10
·期 1
·355-365
·
IF 3.289
Kai Chen,Lei Lei,Yong Qian,Dongjie Yang,Xueqing Qiu
Herein, oil-in-water high internal phase emulsions (HIPEs) were stabilized by lignin from different technical resources with the assistance of alkyl polyglycoside (APG) using an ultrasonic cavitation method. The results showed that the amphiphilicity of lignin determined the formation of HIPEs. Microscopic and rheological characterization indicated that the molecular weight and concentration of lignin, the APG dosage and the oil/water ratio had important influences on the microstructure and stability of the HIPEs. In addition, nutraceutical β-carotene could be encapsulated in the oil phase of the HIPEs, which exhibited outstanding protection against photo- and thermal-oxidative degradation of β-carotene. After storage for 30 days under room temperature/light or storage for 7 days under 55 °C/dark conditions, the retention of β-carotene in the HIPEs was 87% to 95%, which is significantly higher than that of β-carotene dispersed in bulk oil. In vitro digestion experiments indicated that the digestibility of the HIPEs also markedly improved. The largest release of free fatty acids was 80%. The bio-accessibility of β-carotene in these lignin-based HIPEs also reached 60%.
研究领域:
食品科学
·
材料科学
·
营养学
✓ 已验证
DOI
PubMed
高影响因子
Science Advances
·
2024
·Vol. 10
·期 49
·
IF 11.7
Xiaoxiang Li,Jingyi Zhang,Yizhe Liu,Yangzhe Xu,Yixuan Xie,Ting Hu,Benwei Fu,Chengyi Song,Wen Shang,Peng Tao,Tao Deng
Solar-thermal energy storage (STES) within solid-liquid phase change materials (PCMs) has emerged as an attractive solution to overcome intermittency of renewable energy. However, current storage systems usually suffer from slow charging rates, sacrificed storage capacity, and overheating tendency. Inspired by the thermoregulation behavior of Cyprinid fish, here, we present a quick-responsive, ultrafast, large-capacity, overheating-protective STES strategy. We fabricate a liquid-infused solar-absorbing foam charger that can rapidly advance the receding solid-liquid charging interface to efficiently store solar-thermal energy as latent heat and spontaneously float upward to cease the charging process upon overheating. This bioinspired dynamic charging is adaptable to a variety of PCMs, unlocking the potential for safe and efficient utilization of renewable thermal energy.
研究领域:
能源科学
·
材料科学
·
仿生学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COMPOSITES COMMUNICATIONS
·
2024
·
IF 6.5
Xinqiao Wang,Xinlei Jia,Baolu Shi,Donghui Guo,Ning Zhou,Baosheng Xu
Non-ablative thermal protection materials are subjected to localized high-density heat flux, facing extreme temperatures and uneven temperature distribution. Heat dredging is expected to enhance thermal protection efficiency and alleviate its resistance to temperature pressure. In this study, the function of in-plane (IP) heat leading is innovatively incorporated to increase the thermal-protection efficiency of carbon-bonded carbon fiber (CBCF) composites. The modified composite is prepared by a one-step integrated filter press process in which continuous flexible graphite paper (FGP) is used as the heat-leading layer. The typical micromorphology, mechanical response, thermal-insulation and heat-leading performance are determined. The CBCF/FGP composites with a 0.1 mm thick heat-leading layer exhibits a density of 0.22 g/cm 3 . The compressive strength increased by 160 % in the IP direction while remaining consistent in the through-the-thickness direction relative to that of the pure CBCFs. The thermal conductivity in the insulation and heat-leading directions at room temperature are 0.061 W/mK and 21.14 W/mK, respectively, indicating significant anisotropy with an approximately 350-fold difference. The incorporation of FGP effectively enhances the IP heat-leading capabilities of CBCF composites, potentially improving their thermal-insulation efficiency when combined with different matrix materials.
研究领域:
材料科学
·
热力学工程
✓ 已验证
产品关联
DOI
高影响因子
Nature Communications
·
2024
·Vol. 15
·期 1
·1-10
·
IF 14.7
Zou Kailun,Bai Peijia,Li Kanghua,Luo Fangyuan,Liang Jiajie,Lin Ling,Ma Rujun,Li Qi,Jiang Shenglin,Wang Qing,Zhang Guangzu
Thermal management emerges as a grand challenge of next-generation electronics. Efforts to develop compact, solid-state cooling devices have led to the exploration of the electrocaloric effect of ferroelectric polymers. Despite recent advances, the applications of electrocaloric polymers on electronics operating at elevated temperatures remain essentially unexplored. Here, we report that the ferroelectric polymer composite composed of highly-polarized barium strontium titanate nanofibers and electron-accepting [6,6] phenyl-C61-butyric acid methyl ester retains fast electrocaloric responses and stable cyclability at elevated temperatures. We demonstrate the effectiveness of electrocaloric cooling in a polymer composite for a pyroelectric energy harvesting device. The device utilizes a simulated central processing unit (CPU) as the heat source. Our results show that the device remains operational even when the CPU is overheated. Furthermore, we show that the composite functions simultaneously as a pyroelectric energy converter to harvest thermal energy from an overheated chip into electricity in the electrocaloric process. This work suggests a distinct approach for overheating protection and recycling waste heat of microelectronics.
研究领域:
材料科学
·
电子工程
·
能源技术
✓ 已验证
DOI
高影响因子
Food & Function
·
2021
·Vol. 12
·期 16
·7469-7479
·
IF 5.396
Kai Chen,Shengrong Yuan,Dan Wang,Dongming Qi,Fengfeng Chen,Xueqing Qiu
Bacterial infections and multidrug resistance can seriously endanger the health and lives of humans, therefore the development of novel and efficient antibacterial strategies and drugs is urgently needed. Herein, a series of highly biocompatible lysine modified enzymatic hydrolysis lignins (EHL-Lys-x) were synthesized using the Mannich reaction. The sterilizing efficiency of EHL-Lys-2.0 against S. aureus and E. coli at 20 mg mL−1 is 93% and 50%, respectively, which is 26% higher than pure EHL. Quartz crystal microbalance with dissipation monitoring (QCM-D) and atomic force microscopy (AFM) analysis showed that the adsorption and adhesive force between EHL-Lys-x and bacteria increase with the increased amount of grafting of Lys on EHL owing to the increase of the electrostatic interaction between the EHL-Lys-x and bacteria, which results in an improvement in the antimicrobial activity of EHL-Lys-x. Subsequently, EHL-Lys-x combined with alkyl polyglucoside (APG) was used to stabilize the high internal phase emulsion containing curcumin (HIPEs-cur). The dispersed phase fraction of HIPE-cur is 87 vol%, which is the highest internal phase reported to date in the medical research area. The highest residual levels of curcumin in HIPEs are 60-fold, 3-fold and 5-fold compared to that in bulk oil after treatment with UV radiation, thermal emittance and after storage, respectively. The minimum inhibitory concentrations of HIPEs-cur against S. aureus and E. coli were found to be 1.56 and 6.25 mg mL−1, respectively, which are far higher than that of pure EHL-Lys-x. This strategy not only increases the chemical stability and bioavailability of curcumin, but also provides a novel method for the application of lignin in biomedical science.
研究领域:
生物医学
·
材料科学
·
药物开发
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CERAMICS INTERNATIONAL
·
2023
·
IF 5.2
Wenyan Huang,Yufeng Wang,Zhonghao Ning,Shengjian Mao,Zhichao Xue,Yeqi Zhu,Qianwen Tao,Siqi Lan,Rongqian Yao
Making lightweight SiC composite ceramics with good load-bearing and remarkable surficial antioxidant capacity for use in thermal protection system is challenging. In this contribution, an ingenious strategy is reported to produce SiC(Mo x , rGO) nanocomposite polymer-derived ceramics (PDCs) for the first time by reactively re-pyrolyzing flexible polymolybdenumcarbosilane-vinyltriethoxysilane-graphene oxide (PMVG)/rigid SiC(Mo x , rGO) p fillers blends. Highly cross-linked PMVG precursors connect up to five polycarbosilane (PCS) to optimize their formability. In-situ formed MoSi 2 and Mo 4.8 Si 3 C 0.6 , compatible with β-SiC/SiO x C y /C free (rGO) matrix, can effectively strengthen interface bonding, promote nailing cracks, and even hinder β-SiC grain growth. More interestingly, using in-situ SiC nanowires (SiC nws ) by Mo-containing catalyst to decorate samples is an efficient route to reinforce the ceramic network, and SiC nws /SiC(Mo 0.1 , rGO) nanocomposite PDCs display optimal Vickers hardness (5.19 GPa), enhanced fracture toughness (4.26 MPa·m 1/2 ), high compressive strength (151.73 MPa), and low linear shrinkage (4.75%). Such products remain stability/integrity under flame scouring, their surface is covered by a dense SiO 2 passivation layer with good self-healing capacity owing to unique non-destructive oxides of embedded MoSi 2 /Mo 4.8 Si 3 C 0.6 . This work can further provide a feasible way to overcome the critical fabrication process in lightweight porous PDCs with well-balanced high load-bearing and good thermal insulation integration for aerospace vehicle components.
研究领域:
材料科学
·
航空航天工程
✓ 已验证
产品关联
DOI
高影响因子
Case Studies in Thermal Engineering
·
2023
·
IF 6.8
Jiali Hu,Ying Qian,Tongjuan Liu,Tingxuan Wu,Guangyu Zhang,Wei Zhang
Benefiting from the advantages of light weight, porosity, high specific surface area and ultra-low thermal conductivity, silica aerogel (SiAG) has been regarded as ideal thermal insulation material. However, the low strength and fragility limited its application. In this paper, the needled nonwoven (NNW) composed of polyphenylene sulfide fibers and pre-oxidized fibers was applied as substrate for incorporating with silica aerogel (SiAG/NNW) to coordinate the heat preservation. Various characterizations were carried out to discuss thermal insulation property. The results showed that SiAG/NNW can last for 4min under butane flame with a certain impact force at about 1300 °C. According to TG analysis, the weight loss of the SiAG/NNW is 5% at 464 °C, which is much higher than individual NNW (327 °C) or SiAG (456 °C). Moreover, the carbon residue rate of the nonwoven was raised from 54.3% to 73.7% at 800 °C after SiAG incorporation. The fiber morphology can still be observed at the flame perforation of SiAG/NNW with low carbonization degree and no obvious decomposition to SiAG. Significantly, thermal protective performance (TPP) values of the SiAG/NNW can reach 1272 kW s/m 2 which is twice of the NNW. In conclusion, the prepared SiAG/NNW showed high temperature resistance and excellent thermal insulation, the results also provides a technical scheme for future development of thermal insulation materials at high temperature.
研究领域:
材料科学
·
热能工程
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Nano Materials
·
2025
·
IF 5.5
Lu Lu,Jiayi Gu,Xing Wei,Zhenzhen Wei,Yan Zhao
Thermally stable separators, particularly those with a multifaceted and ultrawide range of thermal protection functions, are essential to the long-term safe operation of lithium-ion batteries (LIBs). In this work, we fabricate a sandwiched nanofibrous composite separator (PPPA) that integrates comprehensive thermal protection capacities of heat storage, shutdown, dimensional stability, and flame retardancy together, via a facile combination of coaxial-electrospinning polyacrylonitrile and poly(butylene succinate) nanofibrous membrane (PAN@PBS), spraying a mixture of poly(ethylene glycol) (PEG) and ammonium polyphosphate (APP), and folding techniques. The resultant PPPA separator is able to offer a fibrous network, high porosity, and superior electrolyte affinity. Meanwhile, the thermal protection of the PPPA separator starts with the phase-change heat storage of PEG at 60 °C. Then, the shutdown can be activated at 115 °C by the outer PBS melting of coaxial nanofibers, while the inner PAN maintains dimensional stability up to 250 °C. Further, self-extinguishing will occur in the event of fire due to the existence of APP. Moreover, PEG phase-change leakage of the composite separator can be overlooked due to the hydrogen bonds between PEG and APP and the entrapment of the upper and lower fibers. Furthermore, the PPPA separator demonstrates electrochemical performance that is on par with a commercial polyolefin separator, with higher ionic conductivity (2.49 mS cm–1) and lithium-ion transference number (0.32), as well as a cell discharge capacity retention of 92.4% after 100 cycles at 1 C. Therefore, given its excellent safety and satisfactory performance, PPPA composite separators are anticipated to be a potential separator for LIBs.
研究领域:
材料科学
·
能源技术
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
FOOD AND BIOPRODUCTS PROCESSING
·
2019
·
IF 3.324
Juan Han,Li Wang,Yun Wang,Yunfeng Cai,Yanli Mao,Liang Ni,Xueqiao Xie
The core–shell temperature-responsive Fe 3 O 4 @P(GMA- co -NIPAM)/IDA/Ni 2+ magnetic microspheres were prepared by distillation precipitation polymerization. The morphology, structure, and magnetic property of the magnetic microspheres were characterized by Fourier transform infrared spectroscopy (FT-IR), transmission electron microscopy (TEM), thermogravimetric analysis (TGA), X-ray diffraction (XRD) and vibrating sample magnetometry (VSM). The obtained microspheres show remarkable affinity to bromelain with the maximum adsorption capacity was 117 mg/g. The magnetic microspheres had the capability of thermal protection to the bromelain. UV–vis, FT-IR and circular dichroism (CD) spectra were determined to demonstrate that the process of adsorption and elution had no negative effect on the structure of bromelain. Finally, the microspheres were applied to purification of bromelain from the crude extract of pineapple peel with satisfactory results.
研究领域:
生物化学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2023
·
IF 5.2
Fei Zhong,Chunlin Chen,Daiyu Zhang,Rui Yang,Xusong Huang,Kai Yang,Haoqing Qin,Xulin Yang
Polyaniline (PANI), a polymer with a high nitrogen content, has been shown to have good flame retardant properties. Here, we significantly improved the self-carbon formation ability of PANI at high temperature by doping with phytic acid (PA). Meanwhile, a new organic-metal ion flame retardant (DPANI/PA@Cu) was obtained by introducing Cu 2+ with catalytic carbon formation property into PANI/PA using the complexation between transition metal ions and PA. Surprisingly, the introduction of metal ions was also able to trigger the formation of dendritic structure of PANI (DPANI), which is important for its dispersion in resin matrix and strengthening effect on the coating. The test results demonstrated that the composite coating with 5% content of DPANI/PA@Cu had the lowest back-side temperature (174.9 ℃), the highest expansion height (18.5 mm) and the lowest smoke density class (45.3%). In addition, the DPANI/PA@Cu 5% /EP composite coating retained the maximum amount of residual carbon (29.7%), which was mainly related to the synergistic catalytic effect of PA and Cu 2+ . Ultimately, the retained PANI residual carbon and CuO nanoparticles diffused in the char layer acted as interceptors for the external flame and heat.
研究领域:
材料科学
·
化学工程
·
高分子科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）