MACROMOLECULES
·
2015
·
IF 5.8
Zefeng Song,Ke Wang,Chengqiang Gao,Shuang Wang,Wangqing Zhang
A new multi-stimuli-responsive homopolymer of poly[N-[2-(diethylamino)ethyl]acrylamide] (PDEAEAM), which combines the thermoresponsive and pH/CO2-responsive moieties of the diethylamino and acrylamide groups, was proposed and synthesized by RAFT polymerization. Well-defined PDEAEAM was synthesized by solution RAFT polymerization as indicated by the linear increase in the polymer molecular weight with the monomer conversion and the narrow molecular weight distribution. The appending diethylamino group in the polymer backbone was found to be crucial to determine the thermoresponse of PDEAEAM in water. The parameters including the polymerization degree, the polymer concentration, the deuterated solvent, the terminal attached on the polymer backbone, the additives of salt and urea, and pH and bubbling CO2 affecting the thermoresponse of PDEAEAM in aqueous solution at the lower critical solution temperature (LCST) were investigated. The temperature-variable 1H NMR analysis suggests that the dehydration of PDEAEAM at temperature above LCST is ascribed to the weakened hydrogen bonding between the CONHCH2 and/or (CH2N(CH2CH3)2) moieties with the solvent of water. The proposed multi-stimuli-responsive homopolymer of PDEAEAM has two advantages of (1) the convenient and controllable RAFT synthesis and (2) the pH/CO2 tunable LCST at ∼36 °C being very close to body temperature.
研究领域:
高分子化学
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材料科学
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产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Yilei Fang,Mengyu Tang,Xu Wu,Jiajie Zhang,Qian Guan,Yinzhou Luo,Xin Yu,Ranwen Ou
Trace amount of Cr(VI) in water still threatens human health and ecology. Several reported amine-based adsorbents can remove trace Cr(VI) in acidic solutions of pH 2–5, but perform badly at neutral and alkaline conditions, which is insufficient for treating natural waters. Also, the chemical eluate leads to secondary pollution. Here, the amine-rich thermo-responsive poly(dimethylaminoethyl methacrylate) (pDMAEMA) was selected based on its high pK a value and introduced into MOFs to produce pDMAEMA-DUT-5 for effective removal of trace Cr(VI) from natural waters. The composite with a polymer loading of 23.4 wt% achieved the highest adsorption capacity of 182.2 mg g −1 under an optimized condition, that is, at pH 3 and 25 °C. Besides, this material effectively reduced trace Cr(VI) content in natural waters from 100 to 1 μg L −1 by one filtration in a column. Its high selectivity was verified and further confirmed by the strong adsorption energy of Cr(VI) and −N(CH 3 ) 2 . Furthermore, the composite could be fully regenerated in 45 °C water within 10 min, concentrating Cr(VI) for 270 folds in one adsorption–desorption cycle and maintaining over 99 % performance after five cycles. It demonstrated excellent removal efficiency, high selectivity, and thermal regeneration stability. This work presents a simple strategy to design highly selective and reusable ion adsorbents for effective and sustainable removal or recovery of toxic and precious ions, while its thermal regeneration function largely simplifies further treatments.
研究领域:
环境科学
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
·
2015
·Vol. 53
·期 21
·2469-2480
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IF 3.113
Yong Deng,Xi Wang,Qiulin Yuan,Mengxiang Zhu,Ying Ling,Haoyu Tang
A series of side-chain-functionalized α-helical polypeptides, i.e., poly(γ-4-(3-chloropropoxycarbonyl)benzyl- L -glutamate) (6) have been prepared from n-butylamine initiated ring-opening polymerization (ROP) of γ-4-(3-chloropropoxycarbonyl)benzyl- L -glutamic acid-based N -carboxyanhydride. Polypeptides bearing oligo-ethylene-glycol (OEG) groups or 1-butylimidazolium salts were prepared from 6 via copper-mediated [2+3] alkyne-azide 1,3-dipolar cycloaddition or nuleophilic substitution, respectively. CD and FTIR analysis revealed that the polymers adopt α-helical conformations both in solution and the solid state. Polymers bearing OEG (m = 3) side-chains showed reversible LCST-type phase transition behaviors in water while polymers bearing 1-butylimidazolium and I − counter-anions exhibited reversible UCST-type transitions in water. Variable-temperature UV-vis analysis revealed that the phase transition temperatures ( T pt s) were dependent on the main-chain length and polymeric concentration. © 2015 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2015 , 53 , 2469–2480
研究领域:
高分子化学
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生物材料
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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2022
·Vol. 23
·期 18
·10542
·
IF 6.208
Yuheng Qiu,Kaiqi Ding,Liwen Tang,Ziyu Qin,Mengting Li,Xueqiong Yin
The demand for rare earth metal increases rapidly in the modern high-tech industry and therefore the accumulation of rare earth metal ions from an aqueous environment becomes a significant concern worldwide. In this paper, a water-recyclable chitosan-based La3+-imprinted thermoresponsive hydrogel (CLIT) was prepared to accumulate La3+from solution. The CLIT was characterized by DSC, FITR, Raman spectroscopy, XPS, and SEM, which revealed obvious reversible thermosensitivity and imprinted sites of La3+ions. An adsorption capacity of 112.21 mg/g to La3+ions was achieved on CLIT under its optimum adsorption conditions (pH 5, 50 °C, 60 min). The adsorption could be well illustrated by second-order kinetics and Freundlich isotherm models. The La3+-adsorbed CLIT could be recycled only by rinsing with 10 °C cold water, with a desorption rate of 96.72%. After ten cycles of adsorption-desorption, CLIT retained good adsorption capability. In the solution containing six ions, the adsorption coefficients kLa3+/Mn+of CLIT were 2.04–3.51 times that of non-imprinted hydrogel, with kLa3+/Y3+, kLa3+/Gd3+, kLa3+/Al3+, kLa3+/Fe3+and kLa3+/Cu2+being 1.67, 2.04, 3.15, 2.72 and 4.84, respectively.Keywords:thermoresponsive hydrogel;La3+-imprinting;rare earth metal
研究领域:
材料科学
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环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
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2012
·
IF 1.289
Chun-Hui Du,Chun-Jin Wu,Li-Guang Wu
Amphiphilic copolymer Pluronic F127 was used as macromolecular additive to investigate the polymorphism and thermoresponsive properties of poly(vinylidene fluoride) (PVDF) membranes. Fourier transform infrared spectrometer (FTIR), X-ray diffraction (XRD), and scanning electron microscopy (SEM) were conducted to characterize the polymorphism and morphology of PVDF/F127 blend membranes. FTIR results indicated that F127 existed stably in the blend membranes, and lower F127 concentration in the cast solution was in favor of the formation of α-crystal phase, but higher F127 concentration could promote the formation of β- and γ-crystal phase in PVDF membranes. The results of XRD also confirmed these phenomena. With the increase of F127 in the cast solutions, a more sponge-like structure appeared at the bottom surface of the membranes as investigated by SEM. PVDF/F127 blend membranes also exhibited good thermoresponsive properties. The water flux of the membranes increased distinctly with the increase of the experimental temperature, decreased with the decrease of the temperature, and the increasing and decreasing curves were almost overlapped. Contact angle measurement and permeation experiment indicated that the blend membranes had good hydrophilicity and fouling resistance. © 2012 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
研究领域:
材料科学
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高分子化学
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膜技术
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产品关联
DOI
高影响因子
Polymer Chemistry
·
2013
·Vol. 4
·期 11
·3345-3356
·
IF 5.231
Jianxun Ding,Li Zhao,Di Li,Chunsheng Xiao,Xiuli Zhuang,Xuesi Chen
A series of thermo-responsive “hairy-rod” polypeptides was efficiently synthesized by grafting of azide-terminated (co)polymers of 2-(2-methoxyethoxy)ethyl methacrylate (MEO2MA) or 2-(2-(2-methoxyethoxy)ethoxy)ethyl methacrylate (MEO3MA) (i.e., N3-PMEOiMA) onto poly(γ-propargyl-L-glutamate) (PPLG) through a “click” reaction. The thermo-responsiveness and secondary structure of the resultant polypeptides (i.e. PLG-g-PMEOiMA) were shown to be dependent on the MEO2MA : MEO3MA ratio in PMEOiMA side chains. PLG40-g-P(MEO2MA18-co-MEO3MA9) (P2) and PLG40-g-P(MEO2MA7-co-MEO3MA18) (P4) with lower critical solution temperatures at 25.6 and 34.8 °C, and cloud points at 26.9 and 35.6 °C in physiological saline, respectively, were selected to self-assemble into micelles for doxorubicin (DOX) loading and release. In vitro DOX release from DOX-loaded micelles could be accelerated by a decrease of temperature and pH. Confocal laser scanning microscopy and flow cytometry confirmed the efficient internalization and intracellular DOX release of DOX-loaded micelles towards HeLa cells (a human cervical carcinoma cell line). In vitro methyl thiazolyl tetrazolium assays revealed that the polypeptides were cytocompatible, and DOX-loaded micelles showed efficient cellular proliferation inhibition. Hemolysis tests indicated that micelles were hemocompatible, and the encapsulation with polypeptides significantly reduced the hemolysis ratio of DOX. Therefore, the thermo-responsive polypeptide micelles, which are stable in physiological condition while releasing payloads in the acidic intracellular microenvironment, are promising for smart drug delivery.
研究领域:
生物材料
·
药学
·
肿瘤学
✓ 已验证
产品关联
DOI
高影响因子
POLYMER
·
2016
·
IF 3.586
Yong Zuo,Zhenqian Jiao,Li Ma,Pengfei Song,Rongmin Wang,Yubing Xiong
In this study, novel thermo-responsive nanogels were facilely fabricated via ternary cross-linking copolymerization of ionic liquid (IL)-based monomers and cross-linker in methanol. To achieve the thermo-responsive performance of nanogels, monomers with hydroxyl or carboxyl group which can contribute to hydrogen (H)-bonding interaction is the key point of this strategy. The thermo-responsive behavior of poly(ionic liquid)s (PIL)-based nanogels were testified using dynamic light scattering (DLS), turbidimetric method, and differential scanning calorimetry (DSC) measurements. The results demonstrated that these novel nanogels presented reversible upper critical solution temperature (UCST) phase transition with the temperature changing. And their UCSTs could be tuned via the feed ratio of IL-based monomers and cross-linker. The nanogels were also measured using scanning electronic microscopy (SEM), thermo-gravimetric analyses (TGA) and Fourier transform infrared spectroscopy (FT-IR) techniques. In addition, a possible mechanism of thermo-responsive performance was suggested based on the above results. As a result, our findings provide an efficient and applicable platform for the fabrication of thermo-responsive polymeric nanomaterials .
研究领域:
材料科学
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化学工程
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产品关联
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2014
·
IF 2.538
Zhiping Du,Xiaofeng Sun,Xiumei Tai,Guoyong Wang,Xiaoying Liu
Thermosensitive poly(ethylene glycol) methyl ether methacrylate (POEGMA) was grafted on SiO 2 nanoparticles using activators generated by electron transfer atom transfer radical polymerization (AGET-ATRP) technique. The effects of the amount of ligand, catalyst, ascorbic acid and monomer, as well as the reaction temperature and time were systematically investigated and optimized to get a high grafting density. The structure of the hybrid materials was characterized by Fourier transform infrared (FTIR) spectroscopy, and the morphology was characterized by transmission electron microscopy (TEM) observations. Thermosensitive properties of SiO 2 -POEGMA particles were investigated at different grafting densities by turbidity measurements.
研究领域:
材料科学
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化学工程
✓ 已验证
产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2024
·
IF 8.5
Zhong Li,Huilin Zhou,Xuan Liu,Weifei Wang,Dongming Lan,Yonghua Wang
The limited availability of phospholipase A 1 (PLA 1 ) has posed significant challenges in enzymatic degumming. In this study, a novel PLA1 (UM2) was introduced to address this limitation, which had a unique thermo-responsive ability to switch phospholipase and lipase activities in response to temperature variations. Remarkably, UM2 displayed an unprecedented selectivity under optimized conditions, preferentially hydrolyzing phospholipids over triacylglycerols—a specificity superior to that of commercial PLA 1 . Moreover, UM2 demonstrated high efficiency in hydrolyzing phospholipids with a predilection for phosphatidylcholine (PC) and phosphatidylethanolamine (PE). A practical application of UM2 on crude flaxseed oil led to a dramatic reduction in phosphorus content, plummeting from an initial 384.06 mg/kg to 4.38 mg/kg. Broadening its industrial applicability, UM2 effectively performed enzymatic degumming for other distinct crude vegetable oils with a unique phospholipid composition. Collectively, these results highlighted the promising application of UM2 in the field of oil degumming.
研究领域:
生物化学
·
食品科学
✓ 已验证
DOI
PubMed
高影响因子
ACS Applied Polymer Materials
·
2025
·
IF 4.7
Penghui Wang,Yingying Yang,Yudong Yin,Hua Zhang,Tianqi Shi,Wenjie Zhang,Huiyun Liao,Shuang Li,Xiaoyan Tan,Zheng Yao,Bo Chi
Hydrogel microspheres have attracted extensive attention as the key carriers for drug delivery and cell culture. The traditional microspheres are limited in their application in the regenerative medicine fields due to their closed surface structure and biological inertness. To this end, this study used polylactic acid and selenocysteine modified hyaluronic acid through microfluidic technology and a microsphere surface modification strategy to prepare a hydrogel porous microsphere with reactive oxygen species (ROS) responsive properties and achieved effective removal of ROS through Se–Se rupture. It was then incorporated into a glycopeptide hydrogel, cross-linked by polyglutamic acid and hyaluronic acid, incorporating poloxamer. The glycopeptide hydrogels/microspheres with temperature response characteristics were prepared to reconstruct the dynamic microenvironment required for the repair and regeneration of damaged tissues. The interaction between dynamic and static bonds in the hydrogel system gives the microsphere composite hydrogel excellent injectability, mechanical strength, structural stability, organizational adaptability, and biocompatibility. It can be used as a tissue implant material in the field of tissue regeneration and cell microenvironment reconstruction with a broad application potential.
研究领域:
生物材料学
·
再生医学
✓ 已验证
产品关联
DOI
高影响因子
Materials Chemistry Frontiers
·
2018
·Vol. 2
·期 12
·2212-2219
·
IF 0
Yuting Zhu,Sidi Liu,Xiaoli Shi,Dong Han,Feng Liang
Conductive polymers with stimuli-responsive properties have significant potential for technological applications such as in electrical and biomedical devices, as well as stretchable electronics. In this study, we use the amphiphilic configuration property of α cyclodextrin (αCD) to demonstrate a facile strategy for the preparation of flexible polyaniline (PANI)-containing conductive hydrogel networks based on preorganized αCD-containing N-isopropylacrylamide (αCD-PNIPAM) hydrogels. These materials exhibit high conductivity (0.64 S m−1), excellent thermoresponsive and self-healing properties. The resulting hybrid hydrogels also contain homogeneous, interconnected macropores and exhibit perfect integration between the host phase (αCD-PNIPAM) and the PANI phase, which results in improved mechanical properties and remarkable stability.
研究领域:
材料科学
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生物医学工程
✓ 已验证
产品关联
DOI
JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
·
2018
·Vol. 56
·期 14
·1520-1527
·
IF 2.588
Chunying Wang,Yunhui Li,Yuqin Ma,Ying Gao,Dewen Dong,Jianyong Fang,Ning Zhang
Hydrogen bonding is widely present and plays a significant role in material science and supramolecular chemistry. This work reports a straightforward strategy for the preparation of polymeric nanoparticles from neutral poly(2-oxazoline)s (POx) and tannic acid (TA) driven by their intermolecular hydrogen bonding. Dynamic light scattering (DLS) and scanning electron microscope (SEM) measurements showed that POx bearing different substituents, that is, methyl, ethyl and n -propyl in the 2-position all could assemble with TA into stable nanoparticles in water or ethanol. The diameter of the assembled nanoparticles could be manipulated by varying parameters such as molecular weight of POx, concentration and ratio of POx, and TA. Interestingly, POx/TA nanoparticles exhibited upper critical solution temperature (UCST)-type thermoresponsive properties in ethanol or water depending on the molecular weight and substituent in the 2-position of POx. Increasing or decreasing the temperature at the transition point resulted in the reversible transformation between assembled nanoparticles and disassembled poly(2- n -propyl-2-oxazoline) (PnPrOx) and TA. In view of the tailored size of the stable nanoparticles and the biocompatibilities of POx and TA, the prepared thermoresponsive nanoparticles are promising candidates as carriers for medicine toward related biomedical applications. © 2018 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2018 , 56 , 1520–1527
研究领域:
材料科学
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超分子化学
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生物医学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）