ACS Applied Materials & Interfaces
·
2021
·
IF 9.229
Qilin Wang,Zhao Liu,Chen Tang,Huan Sun,Lin Zhu,Zhuangzhuang Liu,Ke Li,Jia Yang,Gang Qin,Gengzhi Sun,Qiang Chen
The weak adhesion between two hydrogel layers may lead to the delamination of bilayer hydrogels or low force transfer efficiency during deformation. Here, tough interfacial adhesive bilayer hydrogels with rapid shape deformation and recovery were prepared by simple attachment-heating of two gel layers. The bilayer hydrogels, composed of a shape memory gel (S-gel) and an elastic gel (E-gel), exhibited extremely tough interfacial adhesion between two layers (Γ ∼ 2200 J/m2). The shape deformation and shape recovery of the bilayer hydrogels, tuned by “heating–stretching” mode and “stretching–heating–stretching” mode, were rapid (<5 s) and no delamination between two gel layers was detected during shape deformation. Based on the fast shape deformation and recovery, the bilayer hydrogels could mimic the flower and hand, and a gel gripper could be fabricated to catch the object in the hot water. This work provides a simple method to prepare tough adhesive bilayer hydrogels with controlled shape deformation.
研究领域:
材料科学
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聚合物化学
·
软体机器人
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产品关联
DOI
PubMed
高影响因子
MACROMOLECULAR BIOSCIENCE
·
2025
·
IF 4.1
Xiaoyu Liu,Jiayi Jiang,Hailei Liu,Fei Liu,Huarong Shao,Shaojuan Chen,Shaohua Wu
An integrated strategy that combines innovative electrospinning technique with traditional hot-stretching post-treatment is designed and implemented to generate high-molecular-weight poly(l-lactic-acid) (hmwPLLA, Mw = 2 80 000 Da) electrospun nanofiber-constructed yarns (ENCYs). The internal fiber diameter within the hmwPLLA ENCYs is found to increase gradually with the increase of hmwPLLA solution concentration. The hmwPLLA ENCY generated from a concentration of 10% (w v −1 ) is demonstrated with uniform morphology with an average fiber diameter of 737.7 ± 72.2 nm and an average yarn diameter of 454.9 ± 3.5 µm. Compared with the unstretched hmwPLLA ENCY, increasing the hot-stretching temperature can significantly enhance the fiber orientation and crystallinity. Moreover, the mechanical properties of stretched ENCYs are obviously enhanced compared with the unstretched control. The fiber orientation and crystallinity of stretched ENCYs are also found to be significantly improved with the increase of hot stretching rate, further resulting in the obvious increase of breaking strength and Young's modulus. Importantly, the braided textiles made from stretched hmwPLLA ENCYs exhibited great biocompatibility by effectively guiding the cell alignment and supporting the cell adhesion and proliferation. In summary, the high performance hmwPLLA ENCYs show great potential for the future design and development of advanced biomedical textiles.
研究领域:
材料科学
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生物医学工程
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纺织科学
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产品关联
DOI
PubMed
高影响因子
Journal of Materials Chemistry B
·
2021
·Vol. 9
·期 29
·5861-5868
·
IF 6.331
Chen Yuan,Shue Jin,Jiawei Wei,Jinhui Huang,Chang Liu,Xiaoyu Lei,Yi Zuo,Jidong Li,Yubao Li
The deformation shrinkage of a poly(lactide-co-glycolide) (PLGA) fibrous material seriously affects its biomedical application. To demonstrate the underlying shrinking mechanism and to find a method to prevent the shrinkage of an electrospun PLGA membrane, we investigated the shrinking behavior of PLGA electrospun membranes under various test conditions and discussed the underlying shrinking mechanism. The results indicated that the shrinkage of the electrospun PLGA membrane was mainly regulated by the glass transition of its polymer fiber; the temperature and liquid environment were found to be the two main factors leading to the shrinkage of the electrospun PLGA membrane through affecting its glass transition. Then a heat stretching (HS) technique was proposed by us to stabilize the electrospun PLGA membrane. After HS treatment, the glass transition temperature (Tg) of the electrospun PLGA membrane could increase from 48.38 °C to 54.55 °C. Our results indicated that the HS-treated membranes could maintain a high area percentage of 90.89 ± 2.27% and 84.78 ± 3.36% after immersion respectively in PBS and blood at 37 °C for 2 hours. Further experiments confirmed that the HS technique could also stabilize the dimensional structure of the electrospun PDLLA membrane in PBS and blood at 37 °C. This study provides an effective strategy for preventing the shrinkage of electrospun polyester biomaterials in a physiological environment that may benefit both the material structural stability and the in vivo biological performance.
研究领域:
材料科学
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生物医学工程
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产品关联
DOI
PubMed
高影响因子
POLYMER ENGINEERING AND SCIENCE
·
2024
·Vol. 64
·期 6
·2854-2867
·
IF 3.2
Feng Zhang,Xuefeng Pan,Fengtao Li,Jiajia Xu,Xuelian He
Using a solution-mixing method, this research aimed to fabricate high-density polyethylene (HDPE)/ultra-high molecular weight polyethylene (UHMWPE) composite materials with uniform dispersion. By incorporating a small quantity of UHMWPE as a nucleating agent, additional contact points were introduced to enhance the crystallization rate of the HDPE matrix. Thermal stretching experiments were conducted on composite systems with varying UHMWPE contents and molecular weight additions at different temperatures. Elevating the stretching temperature was found to decrease the yield strain and yield strength, extend the stage of tensile plastic deformation, and diminish the overall mechanical properties of the composite material. Notably, stretching at temperatures ranging from 90 to 110°C accentuated the development of internal crystal orientation structures. Under low strain conditions, crystal slip was observed to be concentrated, with single crystals undergoing continuous stretching and breaking, resulting in a decrease in the long period. Conversely, at high strains, the induced formation of oriented lamellar structures was observed. Highlights Prepared HDPE/UHMWPE blends by UHMWPE with varying molecular weights. Analyzed the alterations in the HDPE/UHMWPE blends' internal crystal structure. Influence of UHMWPE addition, temperature on the evolution of crystal structure.
研究领域:
材料科学
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聚合物工程
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产品关联
DOI
高影响因子
ACS Omega
·
2024
·
IF 3.7
Wenning Qi,Liuyang Li,Ruolin Han,Yanbin Hou,Zheng Zhou,Guang-Xin Chen,Qifang Li
Using high-dielectric inorganic ceramics as fillers can effectively increase the dielectric constant of polymer-based composites. However, a high percentage of fillers will inevitably lead to a decrease in the mechanical toughness of the composite materials. By introducing high aspect ratio copper calcium titanate (CaCu3Ti4O12) nanowires (CCTO NWs) and graphene as fillers, the ternary poly(vinylidene fluoride) (PVDF)-based composites (CCTO NWs–graphene)/PVDF with a significant one-dimensional orientation structure were prepared by hot stretching. CCTO NWs and graphene are arranged in a directional manner to form a large number of microcapacitor structures, which significantly improves the dielectric constant of the composites. When the ratio of CCTO NWs and graphene is 0.2 and 0.02, the oriented composites have the highest dielectric constant, which is 19.3% higher than the random composites, respectively. Numerical simulations reveal that the introduction of graphene and the construction of the one-dimensional oriented microstructure have a positive effect on improving the dielectric properties of the composites. This study provides a strategy to improve the dielectric properties of composite materials by structural design without changing the filler content, which has broad application prospects in the field of electronic devices.
研究领域:
材料科学
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电子工程
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产品关联
DOI
PubMed
高影响因子
Advanced Materials Technologies
·
2023
·Vol. 8
·期 11
·2202079
·
IF 6.8
Yu He,Chengwei Wan,Xin Yang,Yuting Wang,Jian Fang,Yuqing Liu
With the increasing demand of smart electronic textiles, fiber-shaped sensing devices have rapidly attracted growing interests, in which elastic fiber sensors can monitor a wider range of strains without compromising their flexibility and adaptability with conventional textiles. However, it is still a major challenge to prepare highly sensitive and durable sensing fibers with multifunction. Herein, using a thermally drawn process, highly stretchable elastomeric fibers that are composited with copper particle-mixed liquid metal electrodes to produce highly elastic piezoresistive strain sensor are fabricated. The composite liquid medal fiber sensor (LMFS) exhibits a strain at break up to 850% and a tensile stress of 6 MPa. When used as a tensile sensor, LMFS can detect large strain levels up to 400%. As a pressure sensor, LMFS can detect an object as light as 0.2 N. The composite fibers can be integrated into a fabric to monitor human motions and Morse code signals. In addition, the fibers can also be applied as an electric heater, the temperature quickly reaches 45 °C at 0.6 V in its original length and 29.3 °C at 0.6 A current with a 250% strain. This work exhibits excellent potential of multifunctional fiber devices in wearable sensing devices.
研究领域:
材料科学
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可穿戴设备
·
传感器技术
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产品关联
DOI
高影响因子
JOURNAL OF POLYMER SCIENCE
·
2024
·
IF 3.9
Kun Li,Shaojuan Chen,Shaohua Wu
An approach that combines a modified electrospinning method with thermal stretching post-treatment is designed to fabricate poly(l-lactide-co-ε-caprolactone) (PLCL) electrospun nanofiber yarns (ENYs). The nanofiber diameter in the PLCL ENYs is found to present an increasing trend with the increasing of polymeric concentration. When the PLCL concentration reaches 13% (w/v), the as-generated ENYs show bead-free and uniform nanofibrous structure. Then, a thermally stretching technique is applied to process the primarily-obtained PLCL ENYs. When the stretching temperature is set as 60 °C, the thermally-stretched PLCL ENYs present superior fiber orientation and notably enhanced crystallinity, thus resulting in dramatically increased mechanical properties. Finally, the thermally stretched PLCL ENYs are further processed into braided fabrics, and their mechanical properties are found to possess an obviously increased trend with the increasing of ENY numbers, demonstrating the adjustment feasibility of the mechanical properties of ENY-based textiles by controlling the ENY numbers. Importantly, the in vitro cell studies demonstrate that the ENY-based braided textiles significantly support the adhesion and proliferation of human dermal fibroblasts (HDFs). In all, the present study provides an easily-handling strategy to fabricate high performance PLCL ENYs, which shows promising future for the generation of advanced biomedical textiles. Graphical
研究领域:
生物材料学
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组织工程学
·
医学材料
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产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2022
·
IF 8.025
Wenchao Yang,Ting Wu,Yueling Chen,Qingyi Huang,Jinqing Ao,Mei Ming,Xiaoyan Gao,Zhengqiu Li,Baoshu Chen
A highly oriented poly( l -lactic acid) (PLLA), with a blood vessel-like biomimetic structure, was fabricated using solid-phase hot drawing technology and homo-epitaxial crystallization to improve the mechanical properties and biocompatibility of PLLA. Long chain branched PLLA (LCB-PLLA) was prepared through a two-step ring-opening reaction, and a consequent draw as high as 1000 % was achieved during the hot drawing. The modulus and tensile strength were found to have increased through the formation of oriented shish-kebab like crystals along the drawing direction during processing. Furthermore, PLLA nano-lamellae were formed on the surface of the oriented plates via the introduction of homo-epitaxial crystallization. The high degree of orientation and epitaxial crystallization substantially enhanced the biocompatibility of the PLLA by prolonging clotting time, decreasing the rate of hemolysis, and increasing the cell growth and reproduction of the osteoblasts.
研究领域:
材料科学
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生物材料工程
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生物医学工程
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产品关联
DOI
PubMed
高影响因子
Biofabrication
·
2021
·Vol. 13
·期 4
·045018
·
IF 10.02
Shaohua Wu,Jiao Liu,Jiangyu Cai,Jinzhong Zhao,Bin Duan,Shaojuan Chen
Fiber constructed yarns are the elementary building blocks for the generation of implantable biotextiles, and there are always needs for designing and developing new types of yarns to improve the properties of biotextile implants. In the present study, we aim to develop novel nanofiber yarns (NYs) by combining nanostructure that more closely mimic the extracellular matrix fibrils of native tissues with biodegradability, strong mechanical properties and great textile processibility. A novel electrospinning system which integrates yarn formation with hot drawing process was developed to fabricate poly(L-lactic acid) (PLLA) NYs. Compared to the PLLA NYs without hot drawing, the thermally drawn PLLA NYs presented superbly-orientated fibrous structure and notably enhanced crystallinity. Importantly, they possessed admirable mechanical performances, which matched and even exceeded the commercial PLLA microfiber yarns (MYs). The thermally drawn PLLA NYs were also demonstrated to notably promote the adhesion, alignment, proliferation, and tenogenic differentiation of human adipose derived mesenchymal stem cells (hADMSCs) compared to the PLLA NYs without hot drawing. The thermally drawn PLLA NYs were further processed into various nanofibrous tissue scaffolds with defined structures and adjustable mechanical and biological properties using textile braiding and weaving technologies, demonstrating the feasibility and versatility of thermally drawn PLLA NYs for textile-forming utilization. The hADMSCs cultured on PLLA NY-based textiles presented enhanced attachment and proliferation capacities than those cultured on PLLA MY-based textiles. This work presents a facile technique to manufacture high performance PLLA NYs, which opens up opportunities to generate advanced nanostructured biotextiles for surgical implant applications.
研究领域:
材料科学
·
生物医学工程
·
组织工程
·
纳米技术
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产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2021
·
IF 9.229
Qian Wang,Qian Zhang,Guangyu Wang,Yuanrui Wang,Xiuyan Ren,Guanghui Gao
Hydrogel strain sensors have attracted tremendous attention in medical monitoring, flexible wearable devices, and human–machine interfaces. However, traditional hydrogels exhibit isotropic sensing performance based on their isotropic structure. Therefore, it is challenging to fabricate a hydrogel with an anisotropic structure similar to human tissues for achieving anisotropic sensing characteristics. Herein, we proposed a simple and effective method for preparing anisotropic poly(vinyl alcohol) (PVA) conductive hydrogels, which demonstrated anisotropic mechanical properties and anisotropic ion conductivity. The anisotropic hydrogel was successfully constructed through first thermal stretching and then directional freezing. The mechanical strength of hydrogels along the parallel stretching direction (stress of 1596 kPa and toughness of 3.69 MJ/m3) was higher than that of the hydrogels along the vertical stretching direction (stress of 883.1 kPa and toughness of 1.96 MJ/m3). Moreover, the hydrogel showed anisotropic conductivity on the advantage of the different ion channels. The prepared hydrogel sensor exhibited anisotropic sensing for multidirectional stress in the strain range from 0.5 to 100%. The gauge factors (GF) parallel to the stretching direction were greater than the GF vertical to the stretching direction. The anisotropic hydrogel sensors are expected to have broad application prospects in flexible wearable devices and medical monitoring.
研究领域:
材料科学
·
生物材料
·
生物医学工程
·
可穿戴技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
EUROPEAN POLYMER JOURNAL
·
2025
·
IF 6.3
Kun Li,Mohashin Kabir,Mahbubur Rahman,Shaojuan Chen
The development of advanced electrospun nanofiber yarns (ENYs) featuring highly aligned structures has garnered considerable attention, as these ENYs serve as fundamental building blocks for biomedical textile fabrication. In this work, we successfully fabricated highly aligned chitosan (CS)/poly(L-lactide-co-ε-caprolactone) (PLCL) ENYs through an innovative combination of electrospinning and thermal stretching techniques. Four CS/PLCL compositions were subjected to thermal stretching at 60 °C to generate 4 times stretching range, resulting in markedly improved fiber alignment and morphological characteristics. Mechanical characterization revealed an interesting trade-off: while Young’s modulus decreased post-stretching, elongation at break increased substantially, indicating enhanced material flexibility. Degradation studies demonstrated composition-dependent behavior, with higher CS content accelerating biodegradation rates. Notably, surface wettability was effectively tuned, as evidenced by water contact angle measurements decreasing dramatically from 130° to 69° with increasing CS content. Most importantly, the 1 % CS/PLCL formulation emerged as particularly promising, demonstrating exceptional antibacterial performance (86.2 % inhibition against E. coli ) coupled with outstanding human dermal fibroblast adhesion and proliferation. Comprehensive evaluation revealed that these highly aligned nanofibers, especially the 1 % CS/PLCL variant, achieved an optimal combination of structural properties (morphology and crystallinity), degradation kinetics, antibacterial efficacy, and biocompatibility.
研究领域:
材料科学
·
纳米技术
·
生物医学工程
·
高分子科学
·
静电纺丝技术
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）