Chemosensors
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2020
·Vol. 8
·期 1
·10
·
IF 3.108
Tian-Tian Wang,Kun Guo,Xue-Mei Hu,Jian Liang,Xing-De Li,Zhi-Feng Zhang,Jing Xie
In this work, a label-free colorimetric assay was developed for the determination of urine glucose using smartphone ambient-light sensor (ALS). Using horseradish peroxidase—hydrogen peroxide—3,3′,5,5′-tetramethylbenzidine (HRP-H2O2-TMB) colored system, quantitative H2O2was added to samples to-be-determined for deepest color. The presence of glucose oxidase in urine led to the formation of H2O2and the reduction of TMBred. As a result of this, the color of the urine faded and the solution changed from deep blue to light blue. We measured the illuminance of the transmitted light by a smartphone ambient light sensor, and thereby color changes were used to calculate the content of urine glucose. After method validation, this colorimetric assay was practically applied for the determination of urine samples from diabetic patients. Good linearity was obtained in the range of 0.039–10.000 mg/mL (R2= 0.998), and a limit of detection was 0.005 mg/mL. Our method was had high accuracy, sensitivity, simplicity, rapidity, and visualization, providing a new sensor to be potentially applicable for point-of-care detection of urine glucose.Keywords:urine glucose;smartphone;ambient light sensor;point-of-care detection
研究领域:
生物化学
·
医学诊断
✓ 已验证
产品关联
DOI
高影响因子
Light-Science & Applications
·
2024
·Vol. 13
·期 1
·1-15
·
IF 20.6
Lv Xulong,Liang Yanjie,Zhang Yi,Chen Dongxun,Shan Xihui,Wang Xiao-Jun
Extensive research has been conducted on visible-light and longer-wavelength infrared-light storage phosphors, which are utilized as promising rewritable memory media for optical information storage applications in dark environments. However, storage phosphors emitting in the deep ultraviolet spectral region (200–300 nm) are relatively lacking. Here, we report an appealing deep-trap ultraviolet storage phosphor, ScBO 3 :Bi 3+ , which exhibits an ultra-narrowband light emission centered at 299 nm with a full width at half maximum (FWHM) of 0.21 eV and excellent X-ray energy storage capabilities. When persistently stimulated by longer-wavelength white/NIR light or heated at elevated temperatures, ScBO 3 :Bi 3+ phosphor exhibits intense and long-lasting ultraviolet luminescence due to the interplay between defect levels and external stimulus, while the natural decay in the dark at room temperature is extremely weak after X-ray irradiation. The impact of the spectral distribution and illuminance of ambient light and ambient temperature on ultraviolet light emission has been studied by comprehensive experimental and theoretical investigations, which elucidate that both O vacancy and Sc interstitial serve as deep electron traps for enhanced and prolonged ultraviolet luminescence upon continuous optical or thermal stimulation. Based on the unique spectral features and trap distribution in ScBO 3 :Bi 3+ phosphor, controllable optical information read-out is demonstrated via external light or heat manipulation, highlighting the great potential of ScBO 3 :Bi 3+ phosphor for advanced optical storage application in bright environments.
研究领域:
材料科学
·
光学工程
·
物理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2022
·
IF 10.383
Shuo Zhu,Binge Deng,Fugang Liu,Jin Li,Li Lin,Jian Ye
Surface-enhanced Raman scattering (SERS) nanoprobes have attracted particular interests in the field of bioimaging owing to their high sensitivity and specificity of the fingerprint spectrum. However, the limited signal-to-background ratio (SBR) in SERS imaging and the requirement to perform imaging in a dark environment have largely hindered its biomedical application. To circumvent this, we have developed a type of bio-orthogonal nanoprobes for SERS imaging with an ultrahigh SBR and ambient light anti-interference ability. The core–shell nanoprobes exhibit strongly enhanced Raman signals and depress the background from photoluminescence of metallic nanoparticles by off-resonance excitation and from the Raman scattering and auto-fluorescence of tissues by near-infrared laser excitation. Such nanoprobes have achieved an SBR of over 100 in SERS bioimaging, 5 times higher than the traditional on-resonant nanoprobes, and their bio-orthogonal signal in the Raman-silent region renders the anti-interference capability under ambient light. The development of these SERS probes opens up a new era for the future applications of Raman imaging in clinical medicine.
研究领域:
生物医学工程
·
分子影像学
✓ 已验证
DOI
PubMed
高影响因子
RADIATION PHYSICS AND CHEMISTRY
·
2024
·
IF 2.8
Jin Dong Cho,Chang Heon Choi,Heerim Nam,Jung-in Kim
The aim of this study is to evaluate and compare the dose sensitivity and ambient light resistance of radiochromic plastic dosimeters (RPDs) incorporating mixed azo compound with those incorporating individual azo compounds. RPDs were fabricated using a mixture of polyurethane , leuco dye, initiator, and solvent. In this study, three azo compounds (tartrazine, sunset yellow , and allura red) were incorporated into RPDs either individually or in combination. Thus, we produced five dosimeter types: one original RPD (A) without azo compounds, three RPDs (B, C, D) with individual azo compounds, and one RPD (E) with mixed azo compounds. Initially, to compare dose response and sensitivity, one group of each sample was delivered to doses ranging from 0.2 Gy to 3 Gy with 6 MV photon beams at 600 cGy/min. To assess ambient light resistance, another group was exposed to light for varying durations. Following irradiation and light exposure, optical density (OD) was obtained using a cone-beam optical CT scanner for each group. Wavelength spectra for each sample were acquired using a spectrometer. This study encompassed analysis and comparison of dose response curves, sensitivity, and netOD-time graphs among samples. Additionally, the absorption wavelength spectra of the samples were compared with the light spectrum emitted by a light bulb. The dose response curves were represented by linear functions, with the slope indicating the sensitivity of each sample. The sensitivity for samples A-E were 0.0759, 0.0988, 0.0902, 0.0809, and 0.1013 ΔOD/Gy, respectively. Samples B-E demonstrated increases in sensitivity of 30.1%, 18.8%, 6.5%, and 33.4%, respectively, compared to sample A. Sample E, which incorporated mixed azo compounds, demonstrated the highest sensitivity and remarkable resistance to ambient light. The results suggested that all azo compounds influenced the sensitivity of the RPDs, and that mixed azo compounds does not reduce the sensitivity of the RPDs. The ambient light resistance was dictated by the overlap between the light bulb's wavelength and the azo dyes' absorption range, which for mixed azo compounds spanned widely from 300 nm to 600 nm. The mixed azo compounds, as opposed to a single azo compound , allowed for the absorption of a wider range of light wavelengths, leading to an increased resistance to ambient light. Our study demonstrated that the inclusion of azo compounds enhances the sensitivity of RPDs. Specifically, the use of mixed azo compounds provided the highest sensitivity and exhibited superior resistance to ambient light. This improved performance can be attributed to the broader absorption wavelength spectrum achievable with mixed azo compounds, enabling absorption across a wider range of light wavelengths. These findings highlight the potential utility of mixed azo compounds in the fabrication of RPDs, enhancing their function as highly sensitive and resistant dosimeters to ambient light.
研究领域:
医学物理
·
辐射测量学
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Huibo Wang,Sidi Liu,Zhibin Xu,Xiaoyu Weng,Changrui Liao,Jun He,Liwei Liu,Yiping Wang,Junle Qu,Hao Li,Jun Song,Jiaqing Guo
Harmful algal blooms (HABs) pose a significant threat to aquatic ecosystems. Conventional anti-algal methods are associated with low anti-algal efficiency, and absence of treatment of toxins released by algae. Therefore, it is essential to establish effective HAB prevention strategies. Artificial nanozymes have a great potential in combating HABs due to their unique catalytic properties. An ultra-small carbon dots nanozyme (VCN) with oxidase-like activity was synthesized in this study. VCN exerts its catalytic effect by catalyzing the production of reactive oxygen species (ROS) from oxygen. VCN was utilized to inactivate hazardous marine algae based on its catalytic properties. It was found that VCN could rapidly remove more than 90% of harmful algae ( Skeletonema costatum and Phaeocystis globosa ) in just 4 h under environmental visible light. To the best of our knowledge, the algae removal efficacy is greater than that of previous reports. Additionally, VCN could attenuate the toxicity of toxins released by algae to counteract secondary pollution caused by algal fragmentation, which is important for practical applications in water pollution caused by algae. Collectively, under applicable and mild conditions, the VCN-presented enzyme activity can efficiently reduce HABs caused harmful pollution.
研究领域:
环境科学
·
纳米技术
·
水生生态学
·
毒理学
✓ 已验证
产品关联
DOI
高影响因子
Information Processing in Agriculture
·
2022
·
IF 0
Xianbao Xu,Zhuangzhuang Bai,Tan Wang
Portable measurement of ammonia nitrogen in water is of great significance for water quality monitoring. It’s beneficial to reduce biological diseases and promote aquatic product safety. Traditional methods such as Nessler’s reagent method suffer from complex operation, time delays and toxic residues. To realize simple and pollution-free detection, this paper develops a low-cost portable device for ammonia nitrogen detection. A test paper was proposed to cooperate the device and offer a chromogenic reaction. The portable device reduces the impact of any ambient light, simplifies the operation, and provides human–computer interaction. The result obtained for the detection range of 0.4–10 mg/L (R 2 are 0.990 2 and 0.989 3 for the rang of 0.4–4.5 and 4.5–10 mg/L, respectively) with the detection limit of 0.36 mg/L, and the average recovery of aquaculture water is 100.98–137.75%. The results show that the portable device can provide a great potential for on-site detection ammonia nitrogen concentration.
研究领域:
环境科学
·
水质分析
·
分析化学
·
水产养殖
✓ 已验证
DOI
Nano Energy
·
2024
·
IF 16.8
Kaiyang Wang,Shuhui Ren,Yunfang Jia,Xiaobing Yan
Central and peripheral biological clocks are essential to regulate creatures’ circadian rhythms, mimicking the biological clock controlled neural and/or immunological responses are research hotspots in the emerging neuromorphic or brain-like systems. However, the current neuromorphic devices still depend on programmable frequency dividing and doubling machine clocks, the high system cost is a challenge to conduct sophisticated brain-like neuromorphic computing. Herein, a dual biological-clocks (including ambient light and endocrine) controllable fibrous synapse crossbar array is proposed. It is demonstrated and confirmed in this work, the Ag conductive filaments, which are critical in the conventional MXene synapses, can be successfully switched by differently biased MoS 2 /MXene heterojunction. The current and power of the unit fibrous synapse in positive/negative switching processes can reach as low as 460 pA/-170 pA and 330 pW/121 pW, respectively. Then, four kinds of logical calculations to the input light signals are accomplished by using the as-prepared fibrous synapse based logical gate. Meanwhile, the light and serotonin combined modulation on the synaptic currents are manifested and applied to simulate the immune-neural responses (memory and the memory exhausted) of T cells in the skin clock. More interestingly, two biological immune compensation mechanisms controlled by the central clock and peripheral clock, namely balanced and reset immune compensation, are also accomplished. This work may pave a new way for promoting the development of dual biological-clock regulated computations in neuromorphic systems.
研究领域:
类脑工程
·
生物钟
·
材料科学
·
神经科学
·
免疫学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）