RSC Advances
·
2014
·Vol. 4
·期 54
·28699-28706
·
IF 3.708
Xiao-kun OuYang,Ru-Na Jin,Le-Ping Yang,Yang-Guang Wang,Li-Ye Yang
Two porous bioadsorbents were successfully prepared from the partial enzymatic hydrolysis of bamboo and subsequent chemical modification with succinic anhydride. We investigated the abilities of the partially enzymatically hydrolyzed bamboo (PEB) and the porous succinylated bamboo (PSB) to adsorb Cd(II) from a solution containing sodium chloride and an amino acid. The partial enzymatic hydrolysis created many pores within the raw bamboo, and both the porous structure and the post-succinylation carboxyl group content were important for high adsorption capacity. The presence of sodium chloride and the amino acid markedly decreased the adsorption capacities of the bioadsorbents. The experimental data could be described perfectly with the Langmuir adsorption isotherm model and pseudo second-order kinetics model. Even in solutions containing sodium chloride and arginine, the maximum Cd(II) adsorption capacities at 303 K were 38.18 and 120.34 mg g−1 for PEB and PSB, respectively.
研究领域:
环境科学
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材料科学
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生物技术
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DOI
高影响因子
COLLOID AND POLYMER SCIENCE
·
2021
·Vol. 299
·期 11
·1833-1841
·
IF 1.931
Haq Fazal,Yu Haojie,Wang Li,Teng Lison,Mehmood Sahid,Haroon Muhammad,Bilal-Ul-Amin,Uddin Md Alim,Fahad Shah,Shen Di
Phenol is the toxicant present in cigarette smoke that causes pulmonary diseases, eyes infection, and even various kinds of cancer. So, in this research, an attempt was done to prepare a suitable absorbent to remove phenol from cigarette smoke. A novel bio-based adsorbent succinylated carboxymethyl starch (S-CMS) was prepared by reacting carboxymethyl starch (CMS) with succinic anhydride (SA) in the presenting of N, N -dimethylformamide (DMF) solvent and pyridine. The structure of the S-CMS was confirmed by spectroscopic techniques including proton nuclear magnetic resonance and Fourier transform infrared. The S-CMS crystallinity and thermal properties were checked by x-ray diffraction and thermogravimetric analysis. The results showed a decrease in thermal properties and crystallinity for S-CMS. The S-CMS were tested as adsorbents for the removal of phenol. The adsorption efficiencies of CMS, S-CMS1, S-CMS2, and S-CMS3 towards phenol were shown to be 0.297 g/g, 0.321 g/g, 0.322 g/g, and 0.324 g/g, respectively. Graphical abstract
研究领域:
环境科学
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材料科学
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化学工程
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DOI
高影响因子
JOURNAL OF POLYMERS AND THE ENVIRONMENT
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2021
·Vol. 29
·期 8
·2676-2685
·
IF 3.667
Haq Fazal,Yu Haojie,Wang Yang,Wang Li,Mehmood Sahid,Haroon Muhammad,Bilal-Ul-Amin,Fahad Shah,Uddin Md. Alim,Shen Di
Succinylated starches (SS) were prepared by the reaction of normal starch (NS) and porous starch (PS) with succinic anhydride (SA) in the presence of DMF solvent and base pyridine, respectively. The proton nuclear magnetic resonance and Fourier transform infrared were used to confirm the successful synthesis of the SS (SS1, SS2, SS3 and SS4, respectively). The X-ray diffractometer XPert PRO (Cu Kα, λ = 1.54 Å) was used to study the crystallinity of NS, PS and SS. The XRD analysis showed that the SS exhibited amorphous nature after succinylation. Thermogravimetric analysis and differential thermal analysis of NS, PS and SS showed that succinylation decreased the thermal stability. The morphology of the NS, PS and SS was studied by SEM. These SS were used as adsorbents for phenol removal. The adsorption efficiencies for phenol by NS, SS1, SS2, SS3 and SS4 were found to be 0.084 g/g, 0.165 g/g, 0.173 g/g, 0.183 g/g and 0.189 g/g, respectively.
研究领域:
化学工程
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环境科学
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DOI
高影响因子
Food Chemistry-X
·
2025
·
IF 8.2
Junliang Chen,Xia Ding,Weiwei Cao,Xinyu Wei,Xin Jin,Qing Chang,Yiming Li,Linlin Li,Wenchao Liu,Tongxiang Yang,Xu Duan,Guangyue Ren
Ultrasound could facilitate the succinylation of protein and improve the function of succinylated protein. However, the effects of ultrasound-assisted succinylation on the physicochemical property and gelation characteristics of PPI were scarely reported. Therefore, this research studied the effect of succinylation with different ultrasonic power on the physicochemical properties and gelation characteristics of succinylated pea protein isolate (PPI). Results displayed that the succinylation degree of PPI increased with the increasing ultrasonic power. The succinylated PPI treated with 318 W/cm 2 of ultrasound power had the lowest turbidity (0.247), and had the smallest particle size (171.3 nm). Excessive ultrasonic power led to the conversion of random coils in succinylated PPI into α-helix structures. Moreover, ultrasound reduced the crystallinity of succinylated PPI. The gel strength of succinylated PPI decreased with the increasing ultrasonic power. The gel strength (65.66 g∙mm) of SPPI treated with ultrasonic power of 636 W/cm 2 was 20.89 % lower than that of SPPI without ultrasonic treatment. Succinylation promoted bound water content in PPI. The content of bound water in the SPPI gel at 636–1273 W/cm 2 ranged from 96.95 % to 98.52 %, which was 2.1 %–3.7 % higher than that in the SPPI without ultrasound treatment. As the ultrasonic power increased, the storage modulus (G′) and loss modulus (G″) of the SPPI gel decreased. Compared to SPPI without ultrasound treatment, the mass loss rate of ultrasonic-treated SPPI at the second stage was significantly reduced by 57.4 %–63.3 %, indicating that ultrasound treatment enhanced the thermal stability of SPPI. This study could offer more evidences for the modification of PPI and develop succinylated PPI gel-based products.
研究领域:
食品科学
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超声学
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蛋白质改性
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材料科学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2024
·
IF 5.7
Xiaoyi Cheng,Wenkang Li,Ruiqi Peng,Yan Chen,Sixian Mu,Lifan Cui,Zhengqin Liu,Huan Wang,Jing Xu,Lianzhou Jiang
The objective of this work was to investigate the effect of succinylation treatment on the physicochemical properties of black bean proteins (BBPI), and the relationship mechanism between BBPI structure and gel properties was further analyzed. The results demonstrated that the covalent formation of higher-molecular-weight complexes with BBPI could be achieved by succinic anhydride (SA). With the addition of SA at 10% (v/v), the acylation of proteins amounted to 92.53 ± 1.10%, at which point there was a minimized particle size of the system (300.90 ± 9.57 nm). Meanwhile, the protein structure was stretched with an irregular curl content of 34.30% and the greatest processable flexibility (0.381 ± 0.004). The dense three-dimensional mesh structure of the hydrogel as revealed by scanning electron microscopy was the fundamental prerequisite for the ability to resist external extrusion. The thermally induced hydrogels of acylated proteins with 10% (v/v) addition of SA showed excellent gel elastic behavior (1.44 ± 0.002 nm) and support capacity. Correlation analysis showed that the hydrogel strength and stability of hydrogels were closely related to the changes in protein conformation. This study provides theoretical guidance for the discovery of flexible proteins and their application in hydrogels.
研究领域:
食品科学
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生物化学
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DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2021
·
IF 7.514
Yao Hu,Chao Qiu,David Julian McClements,Yang Qin,Jie Long,Aiquan Jiao,Xiaojing Li,Jinpeng Wang,Zhengyu Jin
Curcumin is commonly used as a nutraceutical in functional food and beverage formulations because of various biological activities. Typically, curcumin is encapsulated in edible nanoparticles or microparticles to improve its water-dispersibility, chemical stability, and bioavailability. In this study, a succinic acid-modified cyclodextrin (SACD) was fabricated and applied as a carrier for curcumin. Curcumin-loaded SACD (Cur-SACD) with a molar ratio of 1:1 and an encapsulation efficiency > 80% was formed spontaneously basing on hydrogen bonding between the aromatic ring of the curcumin and the hydrophobic cavity of the SACD. Cur-SACD exhibited excellent stability against long-time storage, UV-irradiation, and pasteurization, as well as against physiological conditions including body temperature, physiological salt concentrations, stomach and intestinal pH. This study suggests that Cur-SACD systems may be suitable for increasing the water-dispersibility, stability, and bioavailability of hydrophobic compounds intended for oral administration, such as those used in the food, supplement, and pharmaceutical industries.
研究领域:
食品科学
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药学科学
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营养保健品
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产品关联
DOI
PubMed
高影响因子
FOOD HYDROCOLLOIDS
·
2025
·
IF 12.4
Bin Ma,Haobo Jin,Qi Zeng,Yongguo Jin
Succinylation has attracted extensive research attention in regulating protein functional properties. As the second most abundant protein in egg white, the foaming and gelling properties of ovotransferrin (OVT) are crucial for its applications in the food industry. However, current research on the effects of succinylation on these properties of OVT remains limited. Herein, OVT was subjected to succinylation by different levels of succinic anhydride, with characterization conducted on native OVT (NOVT) and modified OVT (OVTA). Additionally, the effects of different degrees (OVTA1, OVTA2, and OVTA3) of succinylation on foaming ability and stability of OVT were evaluated. Concurrently, the regulatory mechanisms underlying succinylation-mediated modulation of OVT’s thermal aggregation behavior and thermal stability were investigated via visual observation, microstructural analysis, and microrheological measurements. The results showed that succinylation significantly improved the foaming ability and stability of OVT (for half-life, OVTA1 was 2.3-fold that of NOVT), and effectively enhanced the thermal stability of OVT (For melting temperature, OVTA3 was 32.6°C higher than NOVT), thereby inhibiting heat-induced aggregation. This study provides a theoretical foundation for elucidating the regulatory mechanisms of succinylation on OVT functional properties, offering important guidance for expanding OVT applications in food and related fields.
研究领域:
食品科学
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蛋白质化学
·
分子修饰
·
功能食品
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生物物理化学
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产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2021
·
IF 7.514
Fei-Yue Xu,Qing-Hui Wen,Rui Wang,Jian Li,Bo-Ru Chen,Xin-An Zeng
The objective of this study was to investigate the feasibility of pulse electric field (PEF) as a pretreatment for whey protein isolate (WPI) before its succinylation. The degree of succinylation (DS) of WPI increased from 88.31% for native WPI to 93.45% for PEF-pretreated WPI (PWPI, initial pH 10.0) for the same succinic anhydride (SA) to WPI ratio (1:1). Fourier transform infrared spectroscopy and scanning electron microscopy analysis proved the successful succinylation of WPI. For PWPIs, the surface hydrophobicity, exposed sulphydryl, and total sulphydryl decreased, which indicates the occurrence of changes in protein structures with more hydrophilic groups and better protein dispersion. Moreover, PEF may expose more amino acid residues binding sites that are present inside the protein, which is more suitable for succinylation. Therefore, the PEF pretreatment of proteins can improve their efficient use that is expected to play a critical role in succinylation industry.
研究领域:
食品科学
·
生物化学
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产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2019
·
IF 4.784
Tianming Yao,Yadi Wen,Zekun Xu,Mengting Ma,Peng Li,Charles Brennan,Zhongquan Sui,Harold Corke
The impact of starch granule size on 2-octenyl-1-succinic anhydride (OSA) modification remains unclear. To investigate changes of structural, physicochemical, digestibility and emulsifying properties due to OSA modification, five small granule starches (from wheat, rice, oat, quinoa and amaranth) were selected and compared with a standard large granule starch (waxy maize). OSA starches were prepared in 3% (volume by weight) OSA reagent with continuous stirring for 6 h under constant pH of 8.5. The hypothesis was that property changes induced by OSA treatment can be more efficiently achieved in small granule starches (< 10 μm diameter). Small granule OSA starches generally had greater emulsion stability, swelling power and digestibility after gelatinization than waxy maize OSA starch, likely due to the unique physical properties and specific molecular structures of small granule starches, i.e. low sedimentation coefficient, low DP of amylopectin and highly branched amylopectin with short chain length. Granule sizes of OSA starches significantly impact on swelling power, amylose leaching, digestibility and emulsifying capacity, but to different extents depending on botanical origin.
研究领域:
食品科学
·
生物化学
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DOI
高影响因子
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
·
2020
·
IF 2.734
Qinfu Zhao,Yufei Wang,Wei Zhang,Ying Wang,Siling Wang
Oral delivery of nanocarriers is exceedingly limited owing to the two speed-limited processes of epithelial absorption and mucus permeation, which demands totally opposite surface characters of nanoparticles . In order to address this contradiction, we proposed a reasonable idea about functionalizing the surface of mesoporous silica with positively charged amino groups and hydrophilic succinylated casein (SCN) polymer. Mesoporous silica nanoparticles doped with quantum dots (QMSN) with an average particle size at 160 nm were employed as the nanocarriers. Paclitaxel (PTX) with poor solubility and permeability was loaded in the nanoplatforms in a non-crystalline state to realize a relatively high drug loading efficacy of 11.9% and controlled release property. The coated SCN can hinder the premature release in gastric environment, and be specifically detachable in intestine to accelerate PTX release under the existence of trypsin, promote the mucus permeation and result in exposure of amino groups after degradation to realize efficient transepithelial transport. Compared with amino modified QMSN, QMSN-SCN showed increased intestinal uptake in vivo . Toxicity studies showed the both QMSN and QMSN-SCN had the excellent biosecurity for in vivo application. In summary, successive and easy functionalization of amino groups and SCN polymers on the surface of QMSN provide a promising strategy to conquer the multiple gastrointestinal barriers.
研究领域:
药剂学
·
生物医学工程
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产品关联
DOI
高影响因子
STARCH-STARKE
·
2018
·
IF 2.173
Sarkodie Bismark,Zhang Xun,Zhu Zhifeng,Frimpong Charles,Badoe William,Asinyo Benjamin,Howard K. Ebenezer
In this study, amphiphilic starch prepared by phosphorylation and octenylsuccinylation is surveyed to identify its effect on the adhesion of starch to cotton/polyester blend fibers at different temperature. Acid-thinned cornstarch (ATS) is phosphorylated and octenylsuccinylated with pentasodium triphosphate and 2-octenylsuccinic anhydride, respectively, to improve upon adhesion to cotton/polyester blend fibers. Two series of amphiphilic starch samples with different levels of the substitution (DS) are derived for determining desirable level of starch modification in sizing. Amphiphilic starch paste shows strong adhesion to cotton/polyester blend fibers than ATS paste. It is found that the modification reduces the crystallinity, changed the morphology, improves moisture regain, alleviates the adverse influence of starch retrogradation, and improves adhesion to fibers and desizing efficiency. The adhesion of amphiphilic starch paste to cotton/polyester blend fibers at 60 °C is statistically higher than adhesion of ATS at 95 °C. The amphiphilic starch with a total DS of 0.06 shows the highest potential use for strong cotton/polyester blend warp sizing due to its good sizing properties.
研究领域:
材料科学
·
纺织工程
·
有机化学
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产品关联
DOI
高影响因子
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
·
2018
·
IF 2.297
Yunfei Wang,Jin Ren,Yonghua Liu,Rong Liu,Liangliang Wang,Qinglan Yuan,Jianming He,Yamin Nie,Jing Xu,Jingmou Yu
In this study, novel folic acid modified succinylated gelatin (FA-SG) micelles were prepared and used as drug carrier in folate-receptor (FR) targeted antitumor therapy. FA-SG copolymer was synthesized and characterized by 1 H NMR and fluorescence spectroscopy. Doxorubicin-loaded FA-SG (DOX-FA-SG) micelles were prepared by a dialysis method. The shape of DOX-FA-SG micelles was almost spherical by transmission electron microscopy analysis. The mean diameter of DOX-FA-SG micelles was 277 nm , and the DOX-loading content was 12.4%. In vitro drug release of DOX-loaded micelles showed sustained release behavior for 168 h. DOX-FA-SG demonstrated significantly greater cellular uptake and cytotoxicity against FR-positive MCF-7 cells than the non-targeted DOX-loaded micelles. Importantly, DOX-FA-SG micelles exhibited higher antitumor activity in MCF-7 tumor-bearing mice than doxorubicin hydrochloride (DOX⋅HCl) and DOX-loaded micelles without FA modification. Taken together, FA-SG micelles could be an effective carrier for targeted drug delivery .
研究领域:
药剂学
·
药物递送系统
·
癌症研究
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）