ACS Applied Materials & Interfaces
·
2021
·
IF 9.229
Tingting Yan,Yihui Zou,Xiaohui Zhang,Daohao Li,Xiangxin Guo,Dongjiang Yang
The gel polymer electrolyte (GPE) is the key to assembling high-performance solid-state supercapacitors (SSCs). The commercial poly(vinyl alcohol) (PVA) GPE has developed a reputation due to low ionic conductivity endowed by its high crystallinity and poor water retention capacity. In this work, density functional theory (DFT) calculations first revealed that the high crystallinity of PVA can be greatly disrupted by forming hydrogen bonds with natural agarose macromolecules. The hydrogen bond interpenetrated three-dimensional agarose/PVA network offers high water retention and large amounts of channels for movement of Li+ on hydroxyl oxygen atoms. So, an optimized formation of the Li–O coordinate bond (gLi–O(r) = 8.78) and improved diffusion coefficient of Li+ (DLi+) (71 × 10–6 cm2 s–1) were obtained in the agarose/PVA model. When assembled into SSCs, agarose/PVA-GPE with 2 M LiOAc (AP-GPE) exhibits an outstanding specific capacitance (697.22 mF cm–2 at 5 mA cm–2). The high water retention of agarose and large amounts of −OH groups in the agarose macromolecular can generate H2O by dehydration reaction, reducing the flammability of PVA and greatly enhancing the safety of SSCs.
研究领域:
材料科学
·
电化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CARBOHYDRATE POLYMERS
·
2012
·
IF 3.628
Su Yixue,Chu Bin,Gao Yuan,Wu Chaoxi,Zhang Lingmin,Chen Peng,Wang Xiaoying,Tang Shunqing
In order to improve bioactivity of agarose, we modified agarose by carboxylation and grafting dopamine. Under alkaline condition, carboxylated agarose was prepared using 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO) oxidation system by oxidizing C 6 hydroxyl on d -galactose ring into carboxyl group, and the maximum value of the degree of carboxylation reached 30%. With the increase of the amount of oxidant, the molecular weight of the carboxylated agarose decreased to 4 kDa by gel permeation chromatography (GPC) measure. Carboxylated agarose reacted with dopamine through EDC condensation reaction to obtain agarose grafting dopamine (Ag-g-DA), and the grafting rate of dopamine was determined to be 9.3% by UV spectroscopy at 280 nm. The structures of these modified agaroses were determined by FT-IR and 13 C NMR. Both carboxylated agarose and Ag-g-DA showed no cytotoxicity and promoted cell-adhesiveness.
研究领域:
生物材料学
·
细胞生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2023
·
IF 4.1
Hao Chi,Sheng Tian,Xiu Li,Yuchu Chen,Qiumin Xu,Qixiao Wang,Wenwan Shi,Michael Adu-Frimpong,Shanshan Tong
In order to improve the separation process of affinity chromatography that has silica as the main carrier material, we sought to construct Lipid [email protected] 4B affinity chromatography model. We extracted the lipid rafts from U251 cells with a descaler method and sucrose density gradient centrifugation. Afterwards, it was discovered via immunofluorescence that the lipid rafts contain a large amount of tropomyosin-related kinase A (TrkA) protein. Also, agarose powder in the lyophilised state was pretreated, before the lipid rafts were coupled to the agarose gel in a coupling buffer of alkaline pH. CNBr-Sepharose 4B affinity gel packing was characterised using UV spectrophotometric, immunofluorescence and scanning electron microscopic techniques, wherein and the results showed that the lipid rafts were successfully coupled to the agarose gels. Three compounds were used to verify the specific sorption of Sepharose 4B and CNBr-Sepharose 4B, which showed no specific sorption on the materials. Of note, the prepared Lipid [email protected] 4B agarose gels packed with TrkA-rich target proteins could be successfully validated for the active drug gefitinib with high affinity sorption efficiency and eluted with good recovery and reproducibility. This study broadens the range of affinity chromatography carrier materials and provides a reference for research in active drug screening.
研究领域:
生物化学
·
药学
·
生物技术
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2023
·
IF 7.7
Chen Shao,Jian Zhang,Yuqing Liu,Yuting Jiang,Yanping Jia,Guomin Li,Zhong Sun
The presence of antibiotics such as Tetracycline (TC) in the water environment poses new challenges to traditional water treatment technologies . Simple and clean electrocatalytic technology has been widely used in the degradation of antibiotic-based wastewater. In this study, agarose (AG) was loaded onto ITO using an impregnation method, and Pd was deposited onto the AG/ITO electrode by electrodeposition , the Pd/AG/ITO composite electrode was prepared. The electrode was then observed and analyzed using SEM , XRD , FT-IR, and XPS . The optimal conditions for the electrocatalytic reaction were explored as follows: PdCl 2 concentration of 0.20 mmol/L, PdCl 2 deposition current of 3 mA, deposition time of 10 min, and degradation current of 8 mA. Under these optimal working conditions, the Pd/AG/ITO composite electrode achieved a degradation efficiency of 85.21% within 120 min. Through five replications, the degradation efficiency of the electrodes decreased by less than 3.50%, which indicated its good reusability and stability. Based on the generation of active substances during degradation and the analysis of LC-MS, potential degradation products , and degradation pathways were deduced, and it was proposed that the degradation of TC was completed by a synchronous redox reaction co-led by·OH and H*. Toxicity analysis of TC and its degradation products was performed using ECOSAR software. This study will promise to provide an effective method of degrading TC wastewater.
研究领域:
环境科学
·
化学工程
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
Polymers
·
2021
·Vol. 13
·期 22
·4028
·
IF 4.329
Chi Gong,Zhiyuan Kong,Xiaohong Wang
In three-dimensional (3D) bioprinting, the accuracy, stability, and mechanical properties of the formed structure are very important to the overall composition and internal structure of the complex organ. In traditional 3D bioprinting, low-temperature gelatinization of gelatin is often used to construct complex tissues and organs. However, the hydrosol relies too much on the concentration of gelatin and has limited formation accuracy and stability. In this study, we take advantage of the physical crosslinking of agarose at 35–40 °C to replace the single pregelatinization effect of gelatin in 3D bioprinting, and printing composite gelatin/alginate/agarose hydrogels at two temperatures, i.e., 10 °C and 24 °C, respectively. After in-depth research, we find that the structures manufactured by the pregelatinization method of agarose are significantly more accurate, more stable, and harder than those pregelatined by gelatin. We believe that this research holds the potential to be widely used in the future organ manufacturing fields with high structural accuracy and stability.Keywords:3D bioprinting;agarose;pregelatinization;organ manufacturing
研究领域:
生物工程
·
再生医学
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF FOOD ENGINEERING
·
2019
·
IF 3.625
Qijun Wang,Yifei Li,Da-Wen Sun,Zhiwei Zhu
This work aimed at evaluating the effects of high-voltage electric field (HVEF) produced by an improved electrode system on the freezing behaviors and selected properties of agarose gel. The freezing of the agarose gel was realized by a Peltier cooler coupled with an improved electrode system. The electrode system was integrated with a dielectric spacer having high permittivity to avoid partial discharges. Results showed that HVEF combined with a low freezing rate significantly reduced the supercooling degree, enhanced the average freezing rate in particular the nucleation rate, and higher internal electric field intensity showed a better microstructure with smaller ice crystals in frozen samples. Under the highest applied voltage of 9 kV ( E i n = 1.09 E+05 V/m) tested in this study, a 100% supercooling release was achieved. Maximum reductions of 78.83%, 25.79% and 28.75% were observed for the nucleation time, tempering time and total freezing time, respectively, while the phase transition time was prolonged by 14.86% as compared with the control ( p < 0.05). Some reinforcement was detected in the gel strength by increasing internal electric field intensity, but not significant enough to prevent the structural damage and syneresis caused by freezing and thawing. This study suggested that HVEF-assisted freezing was able to reduce the size of ice crystals formed in semi-solid model foods, and the integration of a dielectric spacer with high permittivity to the electrode could be used as a potential method to solve the electrical discharge problem.
研究领域:
食品科学
·
生物物理学
·
冷冻技术
✓ 已验证
产品关联
DOI
高影响因子
BIOTECHNOLOGY AND BIOPROCESS ENGINEERING
·
2017
·Vol. 22
·期 1
·76-82
·
IF 1.16
Gu Jia-Li,Tong Hong-Fei,Sun Lai-Yu
Macroporous magnetic agarose particles (MMAPs) were prepared with calcium carbonate as the porogent by the water-in-oil suspension thermal regeneration method. MMAPs with good sphericity and appropriate particle size were obtained. The physical properties of the beads were determined and it was found that the water content (92.1%), porosity (94.4%) and mean pore diameter (120.1 nm) of the MMAPs were higher than those for the normal magnetic particles, indicating successful generation of macropores after calcium carbonate addition. Compared with normal magnetic particles, the mass transfer of biomolecules in MMAPs was remarkably enhanced. Finally, MMAPs were modified with 5-amino-benzimidazol (ABI) ligand and the adsorption capacity of IgG reached 153 mg/mL, higher than that of the normal magnetic particles (126 mg/mL). Moreover, adsorption behavior of MMAPs to IgG was little changed after twenty-five recycled use. Hence, MMAPs prepared herein showed great potential for bioseparation.
研究领域:
生物化学
·
材料科学
·
生物工程
✓ 已验证
产品关联
DOI
高影响因子
RARE METALS
·
2019
·Vol. 39
·期 4
·375-382
·
IF 1.785
Yazdan Ali,Wang Ji-Zhe,Hu Bing-Kun,Xie Wen-Sheng,Zhao Ling-Yun,Nan Ce-Wen,Li Liang-Liang
Abstract Hydrogels are cross-linked polymers suitable for various applications, but the thermal conductivities of hydrogel-based composites have not been thoroughly investigated. In this study, agarose hydrogel-based composites with various boron nitride (BN) fillers were synthesized and their thermal conductivities were systematically investigated. With the increase in the agarose content from 1.5 wt% to 3.0 wt%, the thermal conductivity of the composite decreased. The composites with BN micropowder had larger thermal conductivities than those of the composites with BN nanopowder at the same filler loading, as the BN micropowder provided better thermal conduction pathways in the hydrogel matrix than those provided by the nanopowder. The maximum thermal conductivity of 2.69 W·m −1 ·K −1 was achieved when 15 wt% microscale BN fillers were added into 1.5 wt% agarose hydrogel, which was 3.5 times larger than that of the pure agarose hydrogel. Additionally, a theoretical model was used to calculate the thermal conductivities of the BN/agarose hydrogel composites; a good agreement was achieved between the experimental and fitting ones. This study demonstrated that the thermal conductivities of hydrogel-based materials can be efficiently and significantly enhanced using BN fillers. Graphic Abstract
研究领域:
材料科学
·
热传导研究
✓ 已验证
DOI
高影响因子
Gels
·
2024
·Vol. 10
·期 4
·266
·
IF 5
Yuxiang Du,Pengjie Jiang,Xin Yang,Rui Fu,Lipeng Liu,Changqing Miao,Yaxiong Wang,Huazheng Sai
Aerogel fibers, characterized by their ultra-low density and ultra-low thermal conductivity, are an ideal candidate for personal thermal management as they hold the potential to effectively reduce the energy consumption of room heating and significantly contribute to energy conservation. However, most aerogel fibers have weak mechanical properties or require complex manufacturing processes. In this study, simple continuous silk fibroin–agarose composite aerogel fibers (SCAFs) were prepared by mixing agarose with silk fibroin through wet spinning and rapid gelation, followed by solvent replacement and supercritical carbon dioxide treatment. Among them, the rapid gelation of the SCAFs was achieved using agarose physical methods with heat-reversible gel properties, simplifying the preparation process. Hydrophobic silk fibroin–agarose composite aerogel fibers (HSCAFs) were prepared using a simple chemical vapor deposition (CVD) method. After CVD, the HSCAFs’ gel skeletons were uniformly coated with a silica layer containing methyl groups, endowing them with outstanding radial elasticity. Moreover, the HSCAFs exhibited low density (≤0.153 g/cm3), a large specific surface area (≥254.0 m2/g), high porosity (91.1–94.7%), and excellent hydrophobicity (a water contact angle of 136.8°). More importantly, they showed excellent thermal insulation performance in low-temperature (−60 °C) or high-temperature (140 °C) environments. The designed HSCAFs may provide a new approach for the preparation of high-performance aerogel fibers for personal thermal management.
研究领域:
材料科学
·
生物工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
STARCH-STARKE
·
2019
·
IF 1.795
Jia Shao,Zheng Zhang,Shixing Zhao,Sui Wang,Zhiyong Guo,Hongzhen Xie,Yufang Hu
As promising soft materials, various excellent properties of hydrogels have received widespread attention during recent years. Mechanical properties and self-healing performance are required characteristics for hydrogels in practical applications. An important challenge is to develop hydrogels exhibiting mechanical performance and self-recoverability through physical cross-linking. In this work, the authors report a hydrogel consisting of a fully physically linked poly (vinyl alcohol)/agarose (PVA/AG) dual-network, which is of high toughness and self-healing properties. The synthesis process of the PVA/AG hydrogel is convenient, with AG as the first network, and hydrogen bonding and crystal-associated PVA as the second network to form a dual physical crosslink. Due to this physical cross-linking, the PVA/AG hydrogel has good mechanical properties (tensile strength of 6.5 MPa to 14.6 MPa, ductility of 168% to 214%). The highest compressive strength of hydrogel is up to 3.66 MPa, which is almost 8 times that of pure PVA hydrogel. In addition, it has excellent self-healing properties without stimulation or healing agents. Compared to pure PVA hydrogel, PVA/AG hydrogels have higher thermal stability due to higher decomposition temperatures and lower degradation rates. In this study, the authors also initially explore the potential application of obtained hydrogel.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Xin Li,Kun Xu,Yiyang Bi,Dongjie He,Xin Wang,Ke Li,Qun Liu,Yu Zhang
A new HKUST-1@covalently crosslinked agarose aerogel (HKUST-1@CCAGA) was synthesized for the highly effective elimination of Methylene Blue (MB). Firstly, the covalently crosslinked agarose aerogel (CCAGA) was obtained by hydrothermal crosslinking reaction with epichlorohydrin (ECH) as crosslinker, which remained stabilized under hydrothermal and solvothermal conditions. Then, HKUST-1 was made to bind to CCAGA by in situ solvothermal assays, and the HKUST-1 loading rate reached 47.4 % based on thermogravimetric data and calculated using the cross over method. Meanwhile, the SEM exhibited the complete 3D honeycomb structure of CCAGA, and HKUST-1 particles uniformly distributed on its layers. Additionally, the specific surface area of HKUST-1@CCAGA can reached 648.59 m 2 ·g −1 . The HKUST-1@CCAGA composite was utilized for MB removal, achieving a high adsorption capacity of 424.30 mg·g −1 at pH 8. The adsorption of MB was also maintained at 80 % after 5 cycles of the experiment. The composite aerogel exhibits good recyclability and has excellent adsorption capacity.
研究领域:
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2025
·
IF 5.4
Xin Li,Xinxin Liu,Dongjie He,Xin Wang,Nuo Xu,Ke Li,Aimin Lv,Qun Liu,Yu Zhang
Organic dyes containing azo/anthropquinone groups pose severe ecological risks due to their toxicity and persistence. Therefore, in this study, covalently cross-linked agarose aerogel was used as the substrate, and the Cu-BTC metal-organic framework (Cu-MOF) was loaded via in-situ growth at room temperature to prepare a Cu-MOF @ agarose composite aerogel (Cu-MOF@AGA) adsorbent. The introduction of Cu-MOF endows Cu-MOF@AGA with more adsorption sites and a larger specific surface area (210.78 m²/g). The characteristic peaks at 2θ values of 6.6, 9.4, and 11.5 in the XRD pattern indicate the successful loading of Cu-MOF. Meanwhile, SEM images show that the 3D macroporous structure of Cu-MOF @AGA provides a rapid mass - transfer channel for pollutant molecules. FT-IR results reveal that Cu-MOF@AGA has more functional groups (such as -OH, -COOH) and active sites. The adsorption mechanism was analyzed using XPS and FT-IR, revealing that the adsorbent achieves adsorption of methylene blue (MB) and Congo red (CR) through hydrogen bonding, π-π interactions, and electrostatic interactions. Kinetic and isotherm fitting analyses demonstrated that the maximum adsorption capacities for methylene blue and Congo red reached 59.48 and 159.85 mg/g, respectively. Finally, after five cycles of adsorption experiments, the removal rates for MB and CR remained above 85 %, indicating that the adsorbent exhibits excellent reusability and promising application potential.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）