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COLLOIDS AND SURFACES B-BIOINTERFACES · 2011 ·Vol. 86 ·期 2 ·345-352 · IF 2.78

Large-scale fabrication of two-dimensional spider-web-like gelatin nano-nets via electro-netting

Xianfeng Wang,Bin Ding,Jianyong Yu,Jianmao Yang

For the first time, two-dimensional (2D) gelatin nano-nets are fabricated by regulating the solution properties and several process parameters during electrospinning/electro-netting. The spider-web-like nano-nets that comprise interlinked one-dimensional (1D) ultrathin nanowires (10–35   nm) are stacked layer-by-layer and widely distributed in the three-dimensional (3D) porous membranes. The final morphology of the gelatin nano-nets, including nanowire diameter, area density and pore-width of the nano-nets, is highly dependent on the solution concentration, salt concentration, kinds of solvents, applied voltage, ambient temperature and relative humidity (RH). The occurrence of rapid phase separation on the splitting-film and the formation of hydrogen bond among gelatin molecules during electro-netting are proposed as the possible mechanisms for the formation of these spider-web-like nano-nets.

研究领域: 生物材料 · 纳米医学 · 组织工程 · 再生医学 · 药物递送 · 生物制造
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