Analytical Methods
·
2021
·Vol. 13
·期 35
·3987-3993
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IF 2.896
Chun Kan,Xing Wang,Linyun Wu,Xiaotao Shao,Haizhu Xing,Min You,Jing Zhu
As a toxic substance, mercury can easily cause harm to organisms and humans. The development of methods that allow rapid detection of low concentrations of mercury ions has a positive effect on the natural environment and human health. The fluorescent probe RBSH reported in this paper has a detection limit as low as 5.9 nM, and a fast response time and allows naked eye detection. We characterized its structure by nuclear magnetic resonance and mass spectrometry, and explored the response mechanism of the probe using Job's plot, and 1H NMR and mass spectrometry. UV-vis spectrophotometry and fluorescence spectroscopy show the excellent optical properties of the probe RBSH. The low toxicity and high cell penetration capacity demonstrated by the cellular assay open up the possibility of biological experiments. By selecting hosts (natural water samples, soybean plants and zebrafish) where mercury ions are likely to be present in the biological chain for low concentration Hg2+ detection, the results all demonstrated the excellent performance of the probe RBSH.
研究领域:
环境科学
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分析化学
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生物医学
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产品关联
DOI
PubMed
高影响因子
BIOORGANIC CHEMISTRY
·
2021
·
IF 5.275
Yingying Zhang,Yanliang Zhao,Bo Song,Kunming Liu,Jiamin Gu,Yiying Yue,Ranhua Xiong,Chaobo Huang
Fluorescence probe combines with fluorescence imaging technology has become the most powerful analytical method with their great advantages of high sensitivity and selectivity and real-time monitoring. Ni 2+ is widely distributed in food, environment and living animals, thereof, it is of great significance for detection Ni 2+ with high selectivity. Herein, a simple strategy is proposed to design and synthesiz a small molecule fluorescent probe Y1 by using “one-pot” method. The spectroscopic behaviors including UV–Vis absorption and fluorescence emission spectrum have been used to verify the feasibility of probe towards Ni 2+ in water/EtOH ( v / v = 2:8) mixtures under neutral condition. As expected, Y1 offers high selectivity and sensitivity for detection Ni 2+ in aqueous solution with a good linear relationship and low detection limit within Ni 2+ concentration variation from 0 to 13 μM ( DOL = 0.0038 μM, R 2 = 0.9983). It is remarkable that Y1 can be applied for real-time visualization Ni 2+ change in sprouted potato and zebrafish with great photo-stability, highlighting that the practicability and feasibility of Y1 to detect and monitor Ni 2+ in the field of food industry and biomedical field.
研究领域:
分析化学
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生物医学
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食品科学
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产品关联
DOI
PubMed
高影响因子
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
·
2023
·Vol. 120
·期 28
·e2302907120
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IF 11.1
Xiaoguang Li,Xianglong Pang,Haohao Jiang,Mei Duan,Heng Liu,Zhujun Yang,Yuhang Xi,Thomas P. Russell
Millifluidics, the manipulation of liquid flow in millimeter-sized channels, has been a revolutionary concept in chemical processing and engineering. The solid channels that contain the liquids, though, are not flexible in their design and modification, and prevent contact with the external environment. All-liquid constructs, on the other hand, while flexible and open, are imbedded in a liquid environment. Here, we provide a route to circumvent these limitations by encasing the liquids in a hydrophobic powder in air that jams on the surface, containing and isolating flowing fluids, offering flexibility and adaptability in design, as manifest in the ability to reconfigure, graft, and segment the constructs. Along with the open nature of these powder-contained channels that allow arbitrary connections/disconnections and substance addition/extraction, numerous applications can be opened in the biological, chemical, and material arenas.
研究领域:
化学工程
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生物学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Brian Musikavanhu,Xin Huang,Quanhong Ma,Zhaoli Xue,Lei Feng,Long Zhao
A novel rhodamine-benzothiazole fluorescent chemosensor, bridged with a thiophene unit, is designed for the turn-on detection of Hg 2+ and Cu 2+ . Noteworthy findings include impressively low limits of detection (0.007 μM for Hg 2+ and 0.013 μM for Cu 2+ ), a determined sensing mechanism involving spirolactam ring opening and hydrolytic cleavage, consistent 1:1 binding stoichiometry for both metal ions and an optimal pH of around 6. The sensor’s practical applicability is demonstrated through successful implementation in HeLa cells and zebrafish, along with effective analyte recovery in various water samples. This work advances the field by providing a highly sensitive and versatile chemosensor for environmental and biological applications.
研究领域:
分析化学
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环境科学
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生物医学
✓ 已验证
产品关联
DOI
高影响因子
Journal of Materials Chemistry C
·
2018
·Vol. 6
·期 38
·10360-10366
·
IF 5.976
Xiaokai Xu,Wei Li,Wan Zhou,Guiping Tan,Yihao Zheng,Chaofan Hu,Bingfu Lei,Xuejie Zhang,Yingliang Liu,Jianle Zhuang
Herein, NaYF4:Yb,Tm@SiO2/carbon dot nanocomposites have been successfully fabricated by a facile route. The structure and morphology of the nanocomposites were characterized by SEM, TEM, XRD, FT-IR and XPS measurements. It was demonstrated that carbon dots were embedded well in the silica layer coating on the surface of NaYF4:Yb,Tm nanoparticles, leading to a relatively stable structure of the nanocomposites. The nanocomposites showed interesting dual-mode luminescence properties, i.e. blue green light under a 365 nm UV lamp and blue purple light under a 980 nm laser. They were utilized to achieve light conversion films, ion detection probes and cell imaging, suggesting their great potential in the fields of anti-counterfeiting and bioapplications.
研究领域:
材料科学
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生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
RSC Advances
·
2015
·Vol. 5
·期 55
·44435-44446
·
IF 3.84
Yangyang Chen,Funian Mo,Shaojun Chen,Yan Yang,Shiguo Chen,Haitao Zhuo,Jianhong Liu
This study reports a novel shape memory copolymer synthesized with 2-(dimethylamino)-ethyl-methacrylate (DMAEMA) and methyl-allyl-polyethenoxy-ether (TPEG) for potential biological applications. In the DMAEMA–TPEG copolymers, TPEG segments form a semi-crystalline phase that serves as the reversible phase, while DMAEMA segments form an amorphous phase containing physical interactive networks that serve as the hard phase. As the TPEG content increases, the crystallinity and the rate of crystallization increase, and the TPEG phase changes from dispersed small spherical crystals to a continuous crystalline phase. Additionally, good crystallinity of the TPEG phase endows the copolymers with good shape fixity, whereas the shape recovery decreases as the TPEG content decreases. DMAEMA–TPEG copolymers also exhibit the multi-shape memory effect with a good triple-shape memory effect. Finally, the investigation of the water contact angle illustrates that all DMAEMA–TPEG copolymers have good hydrophilicity. Thus, it is proposed that DMAEMA–TPEG copolymers might have great potential for biological applications.
研究领域:
材料科学
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生物医学工程
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高分子化学
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Di Tan,Fandong Meng,Yunxia Ni,Wen Sun,Quan Liu,Xin Wang,Zhekun Shi,Qiang Zhao,Yifeng Lei,Shifang Luan,Longjian Xue
Water-durable adhesives are widely explored in various fields like wearable electronics, tissue engineering and sea refloatation. However, in harsh underwater environment, adhesives with sound and comprehensive performance on various surfaces remain highly challenging. Herein, we report a hydrophobic hydrogel adhesive composed of crystalline octadecyl (C18) chains with versatile, robust and thermally switchable underwater adhesion. The inherent hydrophobicity and the amorphous state of C18 chains allow the hydrogel adhesive to conformally adapt to underwater surfaces, independent of surface energy, curvature, charge and roughness as well as the salinity and pH of the water environment. The crystallization of C18 chains greatly increases the modulus of the hydrogel, interlocking the adhesive to the contacting surfaces and resulting in the underwater adhesion up to 275 kPa. The phase change of hydrogel regulates the stress distribution at the contact interface and the adhesion capacity, resulting in a switchable underwater adhesion. The phase change of C18 chains also endows the hydrogel self-healing property, ensuring durability and reusability. Moreover, the temperature of phase change is around ∼ 40 ℃, endowing adhesive with bio-applications in dynamic watery environments. Therefore, the adhesive is highly potential in emerging areas of wearable electronics, tissue engineering and so on.
研究领域:
材料科学
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生物医学工程
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组织工程
✓ 已验证
产品关联
DOI
高影响因子
Micromachines
·
2023
·Vol. 14
·期 10
·1940
·
IF 3.4
Ming Liu,Xianchao Liu,Fuqian Yang
Developing flexible sensors and actuators is of paramount importance for wearable devices and systems. In this research, we developed a simple and facile technique to construct flexible piezoresistive sensors from polydimethylsiloxane films with ridge-like surface structures and laser-induced porous graphene. Using a replication strategy, we prepared the ridge-like surface structures from sandpapers. The piezoresistive sensors exhibit excellent sensitivity with a response time of less than 50 ms and long-term cyclic stability under mechanical loading. The smallest weight they can sense is ~96 mg. We demonstrated applications of the piezoresistive sensors in the sensing of bio-related activities, including muscle contraction, finger flexion, wrist flexion, elbow bending, knee bending, swallowing, respiration, sounds, and pulses.Keywords:flexible sensor;PDMS;surface structure;bio-applications
研究领域:
材料科学
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生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
REACTIVE & FUNCTIONAL POLYMERS
·
2025
·
IF 5.1
Xiujuan Gao,Yichuan Zhang,Mingming Guo
Fluorescent probes generally consisting of a fluorophore and a recognition part can detect and label various substances through the changes of fluorescence properties before and after recognition. In this work, we synthesized a new monomer using the heck coupling reaction, and the polymeric fluorescent probes were prepared via free radical polymerization with two structurally similar monomers. The effects of molecular structures on the luminescent properties (intensity and lifetime) were explored systematically. Ten metal ions were screened at their optimal excitation wavelengths to figure out their corresponding specific recognition ions through the change of fluorescence color and fluorescence signals, and it was found that the fluorescence probes and the ions showed a good linear relationship within a detective concentration range and could also be calculated by the limit of detection formula to reach a lower detect limit (LOD, 0.0027 μM) than before (0.12 μM). Then the potential biological application of the polymers was investigated, and it suggested that fluorescent probes have potential application in sensor devices and bioimaging.
研究领域:
化学
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生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
LANGMUIR
·
2017
·
IF 3.833
Yong Liu,Ying Chen,Yongchao Yao,Kui Luo,Shiyong Zhang,Zhongwei Gu
With the special nature of confined water pools, reverse micelles (RMs) have shown potential for a wide range of applications. However, the inherent water insolubility of RMs hinders their further application prospect especially for applications related to biology. We present herein the first successful transformation of water-insoluble RMs into water-soluble nanoparticles without changing the confined aqueous interiors by hydrolysis/aminolysis of arm-cleavable interfacial cross-linked reverse micelles formed from diester surfactant 1. The unique properties exhibited by the aqueous interiors of the resulting pool-buried water-soluble nanoparticles (PWNPs) were demonstrated both by the template synthesis of gold nanoparticles in the absence of external reductants and by the fluorescence enhancement of encapsulated thioflavin T (ThT). Importantly, the unique potential for PWNPs in biological applications was exemplified by the use of ThT@PWNPs and “cell targeted” ThT@PWNPs as effective optical imaging agents of living cells. This work conceptually overcomes the application bottleneck of RMs and opens an entry to a new class of functional materials.
研究领域:
化学
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生物学
·
材料科学
✓ 已验证
DOI
高影响因子
POLYMER ENGINEERING AND SCIENCE
·
2011
·Vol. 51
·期 8
·1662-1668
·
IF 1.296
Han Ding,Zheng Wang,Lijiao Sheng,Gongwu Song
Polymer ( N , N -dimethyl-ethylamine methacrylate)-block-poly{6-[4-(4-methoxy phenyl-azo) phenoxy] hexylacrylate} p(DMAEMA m - b -AZOM n ) was synthesized by successive reversible addition-fragmentation chain transfer polymerization in the hydrothermal reactor. The products were characterized by hydrogen nuclear magnetic resonance, differential scanning calorimetry, gel permeation chromatography, and ultraviolet and visible absorption spectroscopy (UV-vis). In H 2 O/THF mixture, we found amphiphilic p(DMAEMA m - b -AZOM n ) self-assembles occurred. p(DMAEMA 79 - b -AZOM 7 ) self-assembled into rods, p(DMAEMA 79 - b -AZOM 5 ) self-assembled into giant microspheres with rods wind around, p(DMAEMA 79 - b -AZOM 2 ) self-assembled into microspheres. Photochromic behaviors of the polymers in different environments were investigated. We found the colors of diblock copolymers in films changed from yellow to orange after irradiation by ultraviolet and visible (UV) light. The rates of trans-cis photoisomerization in films were almost the same for the three p(DMAEMA m - b -AZOM n ) copolymers. The rates in aqueous micellar solutions were only marginally faster than those in films for all the three diblock copolymers. The observation of a sizable rate difference in different environments for p(DMAEMA m - b -AZOM n ) suggested that a rotational mechanism might be operative for these water-soluble amphiphilic diblock copolymers. The self-assembly behaviors of three copolymers and the application of p(DMAEMA 79 - b -AZOM 2 ) microspheres in biochemistry were investigated in present work. POLYM. ENG. SCI., 2011. © 2011 Society of Plastics Engineers
研究领域:
高分子化学
·
材料科学
·
生物学
✓ 已验证
DOI
高影响因子
OPTIK
·
2022
·
IF 2.84
Zhiyong Hu,Jinshu Huang,Long Yan,Bo Zhou
Lanthanide-doped near-infrared-II (NIR-II) luminescent nanoparticles have shown great potential in many fields. However, most previous studies were focused on the sensitizer-activator coupled systems in which the NIR-II luminescence intensity is seriously restricted by the low dopants concentration . Improving the NIR-II emission intensity in lanthanide-doped nanoparticles has remained a daunting challenge. Herein, we report a systematic research on the enhancement of the NIR-II luminescence of Er 3+ through lanthanide-mediated energy modulation. It is found that introducing proper content of Yb 3+ , Ce 3+ , Tm 3+ , and Ho 3+ in the erbium sublattice can indeed enhance the NIR-II emission under 980 and 808 nm excitations by mediating the energy transfer processes. Doping of other lanthanide ions (e.g., Pr 3+ , Tb 3+ , Dy 3+ , and Sm 3+ ) only led to a quick decline in luminescence intensity. The NIR-II emission was further enhanced by designing a core-shell-shell nanostructure which consists of an NaYbF 4 interlayer to maximize the absorption of 980 nm excitation. The NIR-II luminescence exhibits superior penetration depth in biological tissue, showing great promise in biological applications .
研究领域:
材料科学
·
光学
·
生物医学
✓ 已验证
产品关联
DOI
高影响因子
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