CARBOHYDRATE POLYMERS
·
2022
·
IF 10.723
Xiaoxiang Han,Zhehao Zheng,Chen Yu,Yunli Deng,Qing Ye,Fuge Niu,Qing Chen,Weichun Pan,Yanbo Wang
In order to improve the solubility and antibacterial activity of chitosan and expand its application range, ionized chitosan (ICS) was successfully synthesized from chitosan through methylation and sulfonation reactions in this study. The chemical structures of the polymers were verified by Fourier transform infrared spectroscopy (FTIR) and 1 H NMR, and a series of characterizations of the polymer were carried out by analytical methods such as element analysis (EA), thermogravimetric analysis (TGA), differential scanning calorimetry (DSC) and X-ray diffraction (XRD). The results showed that the water solubility of the modified ICS was significantly improved. The introduction of propyl sulfonic acid groups with particle size decreasing and potential increasing greatly improved the antibacterial activity of chitosan, indicating that the ICS had the potential as a water-soluble antibacterial agent .
研究领域:
材料科学
·
生物医学
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DOI
PubMed
高影响因子
GREEN CHEMISTRY
·
2015
·Vol. 18
·期 7
·2147-2154
·
IF 8.02
Alei Zhang,Cong Gao,Jing Wang,Kequan Chen,Pingkai Ouyang
In this study, we present an efficient affinity adsorption–enzymatic reaction integrated approach to produce N-acetyl-D-glucosamine (GlcNAc) from crude chitin powders (CP). Chitinase was first purified from the crude enzyme mixture by affinity adsorption on the CP substrate, with ∼92.7% recovery of the enzyme achieved within 10 minutes in the presence of 20 g L−1 of CP under optimized conditions. The chitinase then efficiently converted 40 g L−1 of CP to 39.3 g L−1 of GlcNAc in a batch enzymatic reaction for 4 days, achieving nearly 100% conversion of the substrate CP. The product GlcNAc was easily separated from hydrolysates after destaining, concentrating, crystallizing and drying processes with a high purity of 98%. In addition, the chitinase can be conveniently reused for several batches by the affinity adsorption–enzymatic reaction approach, giving an average yield of 29.6 g L−1 of GlcNAc based on 30 g L−1 of CP as the substrate.
研究领域:
生物化学
·
酶工程
✓ 已验证
DOI
高影响因子
Journal of Coatings Technology and Research
·
2024
·
IF 2.3
Wang Peizhuang,Zhang Li,Hu Zhiqing,Shang Jiaqi,Zhou Jiang
Chitin nanofibers (ChNFs) with different numbers of carboxyls (i.e., with different degree of substitute, DS) were prepared by adjusting the amount of maleic anhydride used in the acylation treatment prior to mechanical nanofibrillation with ultrasound. Transparent coatings were fabricated by using the obtained ChNFs through casting method and modified via vapor deposition by using 1 H , 1 H , 2 H , 2 H -perfluorodecyltrichlorosilane (PFDTS). Hydro-oleophobicity and anti-fingerprint capacity of the ChNF coatings were studied. It was found that the ChNF coatings with more carboxyls possessed stronger hydro-oleophobicity as well as anti-fingerprint capacity after the modification of PFDTS deposition. Analysis of X-ray photoelectron spectroscopy suggested that more PFDTS molecules were grafted onto the ChNF coating surface when the ChNFs had more carboxyls (with higher DS). It is the number of carboxyls rather than hydroxyls on ChNF coating surface that determines hydro-oleophobicity and anti-fingerprint capacity of the ChNF coating surface after the modification of the PFDTS deposition. Graphical abstract
研究领域:
材料科学
·
表面化学
✓ 已验证
产品关联
DOI
高影响因子
CARBOHYDRATE POLYMERS
·
2024
·
IF 10.7
Yizhi Li,Shengyue Tang,Ziang Luo,Kun Liu,Yiting Luo,Wei Wen,Shan Ding,Lihua Li,Mingxian Liu,Changren Zhou,Binghong Luo
Natural bone exhibits a complex anisotropic and micro-nano hierarchical structure, more importantly, bone extracellular matrix (ECM) presents liquid crystal (LC) phase and viscoelastic characteristics, providing a unique microenvironment for guiding cell behavior and regulating osteogenesis. However, in bone tissue engineering scaffolds, the construction of bone-like ECM microenvironment with exquisite microstructure is still a great challenge. Here, we developed a novel polysaccharide LC hydrogel supported 3D printed poly( l -lactide) (PLLA) scaffold with bone-like ECM microenvironment and micro-nano aligned structure. First, we prepared a chitin whisker/chitosan polysaccharide LC precursor, and then infuse it into the pores of 3D printed PLLA scaffold, which was previously surface modified with a polydopamine layer. Next, the LC precursor was chemical cross-linked by genipin to form a hydrogel network with bone-like ECM viscoelasticity and LC phase in the scaffold. Subsequently, we performed directional freeze-casting on the composite scaffold to create oriented channels in the LC hydrogel. Finally, we soaked the composite scaffold in phytic acid to further physical cross-link the LC hydrogel through electrostatic interactions and impart antibacterial effects to the scaffold. The resultant biomimetic scaffold displays osteogenic activity, vascularization ability and antibacterial effect, and is expected to be a promising candidate for bone repair.
研究领域:
生物材料学
·
组织工程学
·
再生医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CARBOHYDRATE POLYMERS
·
2023
·
IF 11.2
Qingqing Tao,Felipe Nunes Henriquez,Kang Ding,Wai Lun Man,Matthew Y. Lui
The application of ionic liquids and deep eutectic solvents offers a promising opportunity for a more environmentally friendly and straightforward chitin purification process from crustacean shells. Nonetheless, the insufficient recyclability of these ionic solvents poses a challenge to the long-term sustainability of such extraction methods. Thus, there is a strong imperative to focus on employing easily recyclable ionic liquids for chitin isolation, enhancing the overall sustainability of the process. In this investigation, a direct chitin purification procedure that utilized pulping liquors consisting of the superbase-based protic ionic liquid 1,5-diazabicyclo[4.3.0]non-5-enium acetate and its precursor, acetic acid, was developed. It was demonstrated that these pulping liquors were capable of simultaneously deproteinate and demineralize shrimp shells to generate chitins with higher purity, degree of N -acetylation and crystallinity than commercially obtained chitin. More significantly, the pulping liquors can be recycled to their pure form in high quantity by simple distillation under reduced pressure, allowing the reuse of these mixtures, which give chitin of nearly identical purity.
研究领域:
生物化学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
DIAMOND AND RELATED MATERIALS
·
2021
·
IF 3.315
Qingsong Ji,Haichao Li
High surface area carbons materials were prepared by a process of carbonization followed by chemical activation of biomass resources of chitin . The characterization of the carbon material was done using Scanning Electron Microscope (SEM), N 2 adsorption/desorption, Fourier Transform Infrared Spectroscopy (FTIR), Elemental Analyzer and X-ray Photoelectron Spectroscopy (XPS). The absorption of the carbon material was studied as kinetically and thermodynamically for the removal of cationic dye, Crystal Violet (CV) from wastewater. The results showed that KOH-activated samples with high BET surface area (2186.3 m 2 g −1 ) and total pore volume (0.9815 cm 3 /g). In some case, the samples are suitable for CV removal for a large range of pH and the removal efficiency is close to 100%. The adsorption process was found to follow pseudo-second order kinetics and Langmuir models. In addition, between 25 and 45 °C, the monolayer maximum adsorption capacity significantly increased and the maximum adsorption capacity was found to be 331.406, 399.943 and 420.068 mg g −1 at 25 °C, 35 °C and 45 °C, respectively.
研究领域:
环境科学
·
材料科学
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产品关联
DOI
高影响因子
CARBOHYDRATE POLYMERS
·
2017
·
IF 4.811
Ping Zhu,Zhongji Gu,Shu Hong,Hailan Lian
For the first time in this study, chitin was solely extracted from lobster shells through a fast, easy and eco-friendly method using deep eutectic solvents (DESs), consisting of mixtures of choline chloride–thiourea (CCT), choline chloride–urea (CCU), choline chloride–glycerol (CCG) and choline chloride–malonic acid (CCMA). The physiochemical properties of the isolated chitins were compared with those of the chemically prepared one and commercial one from shrimp shells. Results showed that CCT, CCU and CCG DESs had no important effect on the elimination of proteins and minerals, while chitin obtained by CCMA DES showed a high purity. The yield (20.63 ± 3.30%) of chitin isolated by CCMA DES was higher than that (16.53 ± 2.35%) of the chemically prepared chitin. The chitin obtained by CCMA DES could be divided into two parts with different crystallinity (67.2% and 80.6%), which also had different thermal stability. Chitin from lobster shells showed porous structure, which is expected to be used for adsorption materials and tissue engineering.
研究领域:
生物化学
·
材料科学
✓ 已验证
DOI
PubMed
高影响因子
IONICS
·
2025
·
IF 2.6
Jia Zhongya,Qi Pengran,Wang Junfeng,Wang Yi,Ma Yanli,Xu Chunjian,Tian Liangliang,Qi Tao
Chitin carbon aerogel (CCA) was prepared from chitin in this work, which exhibits a highly porous fibrous network structure and a large specific surface area (SSA). Molybdenum disulfide (MoS 2 ) nanosheets were synthesized on CCA (MoS 2 -CCA) by a hydrothermal method. The unique structure of CCA prevents the aggregation of MoS 2 and increases its SSA, thereby exposing more catalytic active sites. The catalytic performance of MoS 2 -CCA for the hydrogen evolution reaction (HER) was investigated, and it was found that its catalytic activity significantly outperforms that of MoS 2 supported on chitin carbon (MoS 2 -CC), commercial MoS 2 , and homemade MoS 2 , with a low onset overpotential (151 mV) and good cycling stability. According to the analyses for structure, morphology, surface properties, and element valence states, besides the large SSA and porous structure of CCA, the rich oxygen and nitrogen-containing functional groups in CCA are also useful to the excellent catalytic activity, which increase the content of low-valence Mo and S. The synthesis strategy described herein is simple, and the biomass chitin used is a naturally occurring marine polymer that is inexpensive and non-polluting. This approach offers new avenues for designing high-efficiency HER electrocatalysts.
研究领域:
材料科学
·
电化学
·
可再生资源利用
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2019
·
IF 4.784
Yuan Li,Yubin Ying,Yaqi Zhou,Yujun Ge,Chunhong Yuan,Chunhua Wu,Yaqin Hu
The goal of the study is to develop a novel pH-indicating intelligent packaging by using purple potato extractions (PPE), chitosan and surface-deacetylated chitin nanofibers (CN). Since the major pH-sensitive pigment of PPE was anthocyanin (24.3 mg/g), whether anthocyanins could be loaded on a solid phase to prevent its color fading was further tested. The results of Fourier transform infrared spectrophotometry (FT-IR) and differential scanning calorimetry (DSC) indicated that PPE was efficiently attached into the chitosan film. Meanwhile, adding CN (0.450%, w/v) into chitosan film could significantly enhance the tensile strength (TS), the water-resistant ability and the roughness of chitosan film. Whereas higher content of CN (0.600%, w/v) did not further improve mechanical properties and CN would distribute unevenly due to aggregation in the films. In addition to pH-indicating ability, CS-CN-PPE exhibited the extraordinary antioxidant activities and this provides another advantage of packaging readily oxidizable substances. Taken together, the current study provided a novel and biocompatible packaging with strengthened mechanical property and intelligent pH indicator.
研究领域:
食品科学
·
材料科学
·
生物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Sustainable Chemistry & Engineering
·
2021
·
IF 8.198
Kun Liu,Shengyue Tang,Wenyan Li,Wei Wen,Shan Ding,Mingxian Liu,Hong Li,Changren Zhou,Binghong Luo
To date, designing a perfect poly(d,l-lactide) (PDLLA) bone repair material still remains a major challenge. Inspired by the superior cell affinity, osteogenic activity, and mechanical properties of polysaccharide chitin whiskers, here, positively charged chitin whiskers (HCHW) and negatively charged maleated chitin whiskers (mCHW) are prepared for strengthening and biofunctionalizing the PDLLA membrane via a layer-by-layer (LBL) electrostatic self-assembly method. At a pH value of 4.3, the process of LBL electrostatic self-assembly between the HCHW and mCHW on the membranes is successfully performed, which can be directly proved by the cross-sectional morphology, light transmittance, surface composition, and topography of the membranes. Especially, polydopamine, as an intermediate layer, can greatly enhance the stability and adhesion of the first chitin whisker layer on the PDLLA substrate. Compared with the PDLLA membrane, the mechanical properties of self-assembly membranes are highly enhanced and controllable by adjusting the number of self-assembly whisker layers. Furthermore, in vitro biological evaluations indicate that the HCHW-assembled surface has a higher cell affinity than that of the mCHW-assembled one, which may be attributed to different protein adsorption. Meanwhile, interesting directional cell migration behavior is observed on the HCHW-assembled surface, which can be explained by the guiding effect of surface ordered topology and collective cell migration. These findings provide a new strategy for designing bioactive PDLLA composites with superior and tunable mechanical properties for bone regeneration materials.
研究领域:
生物材料学
·
组织工程学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF POLYMER SCIENCE
·
2023
·
IF 3.4
Hejun Zhan,Yongzhi Chen,Long Huang,Chao Yang,Yalan Zhong,Lihua Wang,Xulin Jiang
Novel water-soluble methylated chitins (MCHs) were synthesized homogeneously in aqueous alkaline solution. The relatively mild reaction conditions resulted in the MCH with high degree of acetylation (DA >0.76). The chemical structure of the obtained MCHs was analyzed and the degree of methylation substitution (DS) and DA were determined by proton NMR in both D 2 O and 20% DCl/D 2 O. The MCH aqueous solutions (DS = 0.46 ~ 0.71) showed a reversible thermosensitive sol–gel–sol transition upon heating and cooling. The gel transition temperature of these MCHs (in the range of 15–85 °C) increased with increasing DS and decreasing polymer concentration. Thermal runaway has been an important safety issue impeding the development of high-energy-density zinc-ion batteries. A smart thermosensitive reversible electrolyte was prepared based on this MCH for the aqueous zinc-ion battery to prevent thermal runaway. When the temperature of zinc-ion battery rises or even gets out of control, the thermosensitive electrolyte can quickly gel and inhibit the migration of zinc ions, resulting in increase of the internal resistance and realizing intelligent and efficient thermal self-protection. Thus the novel thermosensitive methylated chitin shows promise for safe aqueous zinc-ion batteries. Graphical
研究领域:
材料科学
·
能源存储
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Tongtong Ma,Qianqian Zhou,Liping Li,Mingzhu Pan,Chuigen Guo,Changtong Mei
MXene has proved a bright prospect for developing intelligent fire-warning sensors, which is an emerging field but suffers from poor thermal oxidation stability and low flame retardant efficiency. Herein, a nacre-inspired bridging network constructed by MXene and chitin nanocrystals (ChNCs) with early fire-warning and high fire prevention was fabricated through low-temperature evaporation assembly approach. When encountering a fire source, such insulated network can independently construct a conductive path and then trigger the fire-warning signal owing to the char-forming and bridging effect of ChNCs. Typically, the ChMXene network incorporated with 30 wt% of adenosine triphosphate (ATP) (ChMXene-30) exhibits an ultrafast fire alarm signal of only 0.78 s and an ideal response time of 290 s. The thermal oxidation resistance, insulation performance and fire protecting properties of the network were drastically enhanced by the synergistic intumescent flame retardant effect of ChNCs and ATP. The corresponding enhancement mechanism was ascribed to the quenching effect of phosphorus-based radicals and diluting effect of non-combustible gases in the gas phase, the barrier effect of intumescent char layers as well as the effect of blowing-out fire in the condensed phase. This work offers a novel strategy to achieving sensitive fire-warning and reliable thermal oxidation resistance of MXene network for protection applications in disparate major fire potential and related hazardous environments.
研究领域:
材料科学
·
消防安全
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）