Applied Materials Today
·
2021
·
IF 10.041
Rencheng Zhuang,Dekai Zhou,Xiaocong Chang,Yi Mo,Guangyu Zhang,Longqiu Li
Design and synthesis of electric-driven micro/nanomotors (EDMNMs) have attracted tremendous attention because of their unique advantages, such as non-necessity of fuel, high mobility, and flexible controllability. However, existing EDMNMs are mostly Janus structures based on two hemispheres made from heterogeneous materials . Here, we propose a new type of defective electric-driven micro/nanomotor with an asymmetric shape. It is found, for the first time, that the defective golden micro/nanomotors (DGMs) can generate a locally asymmetric field gradient through the topological defect, and can achieve controllable self-dielectrophoresis (sDEP) and induced-charge electrophoresis (ICEP) motion behaviors in different frequency ranges. In particular, the DGMs can achieve three-dimensional helical motion behavior through designing their defective structure. Furthermore, we demonstrate that the DGMs can attract or repel cargos under different electric frequencies. These new DGMs and their attractive performance pave the way for fabricating highly controllable EDMNMs via structural design and can be widely applied in biomedicine, micro/nanosensors, and micro/nanomechanical systems.
研究领域:
材料科学
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生物医学工程
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纳米技术
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产品关联
DOI
高影响因子
ELECTROPHORESIS
·
2014
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IF 3.161
Ying Feng,Tingting Wang,Zhengjin Jiang,Bezhan Chankvetadze,Jacques Crommen
A series of eight chiral β-blocker drugs, acebutolol, atenolol, carazolol, carteolol, carvedilol, propranolol, sotalol, and talinolol, have been enantioseparated using two single-component anionic β-CD derivatives, namely heptakis (2,3-di- O -methyl-6-sulfo)-β-CD (HDMS-β-CD) and heptakis (2,3-di- O -acetyl-6-sulfo)-β-CD (HDAS-β-CD), in aqueous CE and NACE. The influence of the nature of substituents (methyl or acetyl) in positions 2 and 3 on the CD derivatives and of the electrophoretic medium (water or methanol) on the enantioselectivity and enantiomer affinity pattern (EAP) of these structurally related compounds was systematically studied. All eight β-blockers could be enantioseparated at least partially in the four CE systems, except sotalol with HDMS-β-CD in NACE. In general, lower affinity and enantioselectivity were obtained in the presence of HDMS-β-CD compared to HDAS-β-CD. Reversals of EAPs were observed for all compounds. EAPs toward these two CDs were found to be opposite to each other in NACE for all compounds except carvedilol and in aqueous CE for atenolol, carteolol, talinolol, and sotalol. It is particularly noteworthy that opposite EAPs were also observed using the same CD derivative when the aqueous BGE was replaced with the methanolic one: for carazolol, carvedilol, and propranolol in the presence of HDMS-β-CD and for acebutolol and carvedilol with HDAS-β-CD.
研究领域:
药物化学
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分析化学
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产品关联
DOI
PubMed
高影响因子
Journal of the Taiwan Institute of Chemical Engineers
·
2021
·
IF 5.876
Jiaxin Huang,Yatian Zhang,Chunxian Tao,Shanni Li,Qingxiang You,Dawei Zhang,Zhenqing Li,Yoshinori Yamaguchi
Background Capillary electrophoresis (CE) is an effective method for protein analysis. Although previous researchers have proved that the separation performance of large DNA molecules was improved by pulsed field capillary electrophoresis (PFCE), there is lack of research about proteins separation by PFCE. Methods Herein, we systematically investigated the separation performance of proteins sized from 44 kDa to 200 kDa under square wave and inversion electric field, respectively. Findings Results showed that for pulsed electric field with same forward and backward time duration, there was a resonance frequency for protein molecule re-orientation and applied frequency, and the apparent mobility ( μ ) was the lowest at the resonance frequency. μ was positively correlated to modulation depth ( M ) if M was below 200%, while μ was negatively correlated to M if M was higher than 200%. For CE with same forward and backward voltage, it demonstrated that μ dropped as M went up, but the separation performance for proteins with high molecular mass improved. Through PFCE, albumin and α- globulins in human serum were also resolved within 7 min. Such a work may shed new light on the analysis of proteins by PFCE.
研究领域:
分析化学
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生物技术
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生物化学
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产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
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2020
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IF 8.758
Hongli Li,Fengyun Li,Lizhi Zhao,Lei Zhao,Ping Sun,Jing Wu,Xiayan Wang,Qiaosheng Pu
Electrophoretic separation in short microchannels is a promising way for rapid analysis of biomolecules, but the pressurized laminar flow may compromise the separation efficiency. In this work, through an electric field, instant formation and removal of a solid chitosan/β-glycerol phosphate (CS/β-GP) hydrogel within microchannels of microchips were realized. In a typical cross-type microchip, the CS/β-GP hydrogel was precisely formed in the separation microchannel within 15 s of the application of a voltage of 2000 V. Highly efficient separation of peptides and proteins was achieved, and theoretical plate numbers of 0.6 to 1.5 × 106/m were attained for proteins in 120 s. The used hydrogel could be swiftly removed also with an electric field, and the whole procedure was achieved on a standard microchip electrophoresis device with no extra accessory or special operation required.
研究领域:
生物化学
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分析化学
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材料科学
✓ 已验证
DOI
高影响因子
MICROCHEMICAL JOURNAL
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2024
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IF 4.9
Xin-Ran Ma,Yi-Wen Wu,Qian-Xue Shen,Yan-Hua Jiao,Jun Cao,Li-Hong Ye
One-step admicelle to cyclodextrin sweeping (ACDS) method in capillary electrophoresis (CE) has been developed for the separation and preconcentration of toxic aristolochic acids (AAs) by applying cetyltrimethylammonium chloride (CTAC) between the critical micelle concentration and critical surface aggregation concentration. The analytes were captured into the CTAC admicelles, after the more stable inclusion complexes were formed, the release and preconcentration of the analytes could be realized. The CE enrichment parameters, such as the types of cationic surfactants and cyclodextrins (CDs), the concentration of cationic surfactants, disodium tetraborate decahydrate (borax) and CDs, the volume ratio of acetonitrile (ACN) in background electrolyte (BGE) and the sample injection time were optimized systemically. The optimal BGE was composed of 20 mM borax, 10 mM γ-CD and 10 % (v/v) ACN, the sample matrix consisted of 0.2 mM CTAC, 20 mM borax and five analytes. The limit of detection of this method was 3–6 ng/mL, and good linearity values (R 2 ) were obtained for five AAs in the range of 0.997–0.999. Applying optimized conditions, the enrichment efficiencies of five AAs were enhanced with the sensitivity enrichment factors of 30–68. The sweeping approach was successfully applied to the determination of A, B, Ⅶ a , C and D in Aristolochia and Asarum samples, which could provide a potential in the enrichment of the other toxic compounds.
研究领域:
分析化学
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毒理学
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产品关联
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2022
·Vol. 33
·期 9
·6262-6272
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IF 2.779
Guo Xiaogang,Liang Taotao,Liu Guixiu,He Yuanzhen,Kong Shuying,Islam Md. Labu,Yuan Binfang
Achieving controllable film-forming process is always a difficult issue for practical application, especially for bi-/multiple component composite materials. Thus, this paper firstly developed a conveniently and controllable electrophoretic assembly technique under mild conditions to design nano-Al-doped@Co 3 O 4 energetic film with wide potential applications. The stable suspension consists of isopropyl alcohol with the tracing of polyethylenimine and tween 80. The high crystallinity and uniformity of structure in target films were demonstrated by FESEM, EDX, XRD, and FT-IR techniques. Electrophoretic assembly dynamics of Al/Co 3 O 4 particles were deeply explored to provide a theoretical foundation for optimizing exothermic performance. The exothermic performance of target film can be accurately adjusted, and the output of heat ( Q ) and activation energy ( E a ) can reach up to ~ 3.6 kJ/g (close to 85% of theoretical value) and low to 230.01 kJ/mol, respectively. This breakthrough will substantially push forward the facile functional film-forming process of different kinds of particles used in fields of electronics, military, aviation, etc.
研究领域:
材料科学
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能源科学
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产品关联
DOI
高影响因子
Micromachines
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2022
·Vol. 13
·期 8
·1235
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IF 3.523
Zhi Zhang,Yao Wang,Qun Chen,Qingguo Gao,Liming Liu,Jianjun Yang,Xinjian Pan,Yu Miao,Feng Chi
The electrophoretic display (EPD) has attracted widespread attention due to its great visual perception, energy-saving, portability, and bistability. However, the EPD still has many problems in response time, colorization, etc., which limits its practical application. In this paper, novel blue electrophoretic particles were prepared with copper (II) phthalocyanine and high ionization 1-butyl-1-methyl piperidinium bromide mono ionic liquid. It was shown that electrophoretic particles dispersed in a non-polar tetrachloroethylene medium had high Zeta potential and electrophoretic mobility. At the same time, electrophoretic particles showed better dispersion stability. Finally, the prepared blue electrophoretic particles and white titanium dioxide particles were compounded to prepare blue and white dual-color electrophoretic dispersion. An EPD cell was made to test its performance. The results showed that the prepared blue and white dual-color electrophoretic dispersion could realize a reversible response. Piperidine mono ionic liquid increased the surface potential of copper (II) phthalocyanine from +30.50 mV to +60.27 mV, enhancing it by 97.61%. Therefore, we believed that modifying particles with high ionization mono ionic liquid had great applicability to the modification of electrophoretic particles, and blue particles prepared with piperidine mono ionic liquid as a charge control agent (CCA) were excellent candidates for EPDs.Keywords:zeta potential;ionic liquid;copper (II) phthalocyanine;electrophoretic particle
研究领域:
材料科学
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电泳显示器
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纳米技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ENVIRONMENTAL POLLUTION
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2023
·
IF 8.9
Kai Zhao,Xun Zhao,Tianbo Gao,Xuan Li,Guanqi Wang,Xinxiang Pan,Junsheng Wang
A novel dielectrophoresis (DEP)-assisted device for the bioremediation of heavy metal ions by using Chlorella microalgae is presented in this paper. To generate the DEP forces, pairs of electrode mesh were inserted in the DEP-assisted device. By applying DC electric field via the electrodes, the inhomogeneous electric field gradient is induced and the strongest non-uniform electric field exists near the mesh cross-corner. After the adsorption of Cd and Cu heavy metal ions by Chlorella , the Chlorella chain were trapped along the vicinity of the electrode mesh. Then, the effects of Chlorella concentration on the adsorption of heavy metal ions, and the applied voltage and electrode mesh size on the removal of Chlorella are conducted. In the co-existing Cd and Cu solutions, the individual adsorption ratio of Cd and Cu reaches as high as approximately 96% and 98%, respectively, showing excellent bioremediation capability of multiple heavy metal ions in wastewater. By adjusting the applied electric voltage and the mesh size, the Chlorella adsorbed with Cd and Cu are captured by negative DC-DEP effects and the removal ratio of Chlorella reach an average of 97%, providing a method for the removal of multiple heavy metal ions in wastewater by using Chlorella microalgae.
研究领域:
环境科学
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生物学
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产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING SCIENCE
·
2023
·
IF 4.7
Mide Luo,Yali Zhao,Yanying Wei,Haihui Wang
Construction of large-area two-dimensional (2D) nanosheet membranes for gas separation, particularly tubular membranes, is extremely challenging. Here, electrophoretic deposition technology was employed to construct large-area tubular 2D MXene membranes for H 2 /CO 2 gas separation, where the membrane with a single tube area of 25 cm 2 could be successfully manufactured in approximately 5 min under optimal process conditions. The membrane exhibited good H 2 /CO 2 separation performance with H 2 /CO 2 selectivity of 53.0 and hydrogen permeance of 133.8 GPU, exceeding the 2008 Robeson upper bound, and showed excellent stability in long-term test with water vapor evaluations for more than 350 h. Additionally, some engineering issues and operation parameters concerning the separation performance of H 2 /CO 2 in single-module and dual-module separators have been thoroughly investigated and analyzed. This work has taken an important step toward the industrialization of 2D MXene membranes and also provided significant guidance to other 2D material-based membranes in approaching practical applications.
研究领域:
材料科学
·
化学工程
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产品关联
DOI
高影响因子
DENTAL MATERIALS
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2021
·
IF 5.304
Danlei Zhao,Haoran Dong,Yuting Niu,Wenjie Fan,Muqi Jiang,Ke Li,Qingsong Wei,William M. Palin,Zhen Zhang
Objective Guided bone regeneration (GBR) techniques use barrier membranes to augment the alveolar ridge for the site-specific growth of bone defects. However, current approaches using cast metal substructures exhibit poor adaptation to the surgical site and increased risk of infection. This study aimed to fabricate multi-functional coatings with 3D-printed porous titanium-niobium (Ti-Nb) alloy meshes to maintain space, prevent the ingrowth of fibroblasts and inhibit the colonization of bacteria for GBR. Methods Ti-Nb alloy meshes were prepared by selective laser melting (SLM) and used as substrates for novel surface coatings. Porous chitosan (CS)/ gelatin (G)/ doxycycline (Dox) coatings were formed on the meshes using electrophoretic deposition (EPD) and freeze-drying. The process of EPD was characterized through Fourier transform infrared spectroscopy (FT-IR), zeta potential, and particle size analysis. The cytotoxicity of the coatings was evaluated through the culture of osteoblasts and immunostaining. The antibacterial activity of the coatings was tested using inhibition zone tests against Staphylococcus aureus ( S. aureus ) and scanning electron microscope (SEM). The inhibition of fibroblasts infiltration and nutrients transfer properties were analyzed using immunostaining and permeability tests. Results High yield strength (567.5 ± 3.5 MPa) and low elastic modulus (65.5 ± 0.2 GPa) were achieved in Ti-Nb alloy bulk samples. The data of zeta potential, FT-IR and SEM indicated that porous spongy coatings were chemically bonded following EPD. In vitro analysis of CSGDox1 (containing Dox at 1 mg·mL −1 ) coating revealed its antibacterial effect and biocompatibility. Moreover, the CSGDox1 coating was proved to be effective for preventing the ingrowth of fibroblasts, whilst allowing the infiltration of nutrients. Significance This study verified that the EPD of CSGDox coatings on the 3D-printed Ti-Nb meshes can maintain space, provide antibiotic release whilst maintaining a barrier against soft-tissue growth, which is essential for the success of GBR treatment.
研究领域:
生物材料学
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口腔医学
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组织工程学
✓ 已验证
DOI
PubMed
高影响因子
CHEMISTRY-A EUROPEAN JOURNAL
·
2024
·
IF 3.9
Minjie Wu,Teng Chen,Xuedan Chen,Maoxue Wang,Chen Lv,Kai Meng,shuanglong Yuan
Perovskite-based photodetectors (PDs) are broadly utilized in optical communication, non-destructive testing, and smart wearable devices due to their ability to convert light into electrical signals. However, toxicity and instability hold back their mass production and commercialization. The lead-free Cs2AgBiBr6 double perovskite film, promised to be an alternative, is fabricated by electrophoretic deposition (EPD), which compromises film quality. Herein, we improved the quality of the Cs2AgBiBr6 films and the performance of PDs by adding N-acetylethylenediamine (DEAC) to Cs2AgBiBr6 perovskite precursor for EPD, in which the ligand DEAC provides a pair of lone electrons to Bi3+, forming coordinate covalent bonds. The optimized PDs have high detectivity, up to 4.4×1012 Jones, and high stability in the air. The high-performance, flexible Cs2AgBiBr6 perovskite PDs were fabricated on this basis, it also achieved the detectivity up to 3.2×1012 Jones with excellent bending cycle stability. These results propose a feasible approach to improving the crystallization of double perovskite thin films by introducing ligands during the EPD process. Furthermore, they demonstrate enhanced optoelectronic performance, indicating that this method is also applicable to halide perovskites, offering an effective strategy to improve their film quality.
研究领域:
材料科学
·
光电子学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2017
·
IF 3.981
Chen Zhao,Yan Yang,Linfang Wei,Qinghua Guo,Hao Fang,Shaolin Chen,Qiang Hua
Yarrowia lipolytica is an oleaginous yeast with promise in producing terpenoids such as lycopene . Though methods for analyzing primary metabolic intermediates have been established, further work is needed to better analyze nucleotides and coenzymes . Here, we presented an optimized method for the separation of nucleotides and coenzymes in Y. lipolytica using the capillary electrophoresis. The separation of twelve metabolites including four coenzymes, five nucleotides and three nucleosides was achieved within 32 min using a voltage of 15 kV and 70 mM sodium carbonate/hydrogencarbonate buffer with 1.0% β -CD at pH 10. The results show that the concentrations of adenosine triphosphate and nicotinamide adenine dinucleotide phosphate changed significantly between lycopene producing strain and the control, indicating that these two metabolites may be closely related with lycopene production. The optimized method provides a useful approach for future metabolic analysis of fermentation process as well as industrial strain improvement.
研究领域:
生物化学
·
代谢工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）