Advanced Healthcare Materials
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2024
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IF 10
Luyao Xiang,Jinlong Hu,Xu Yan,Huai Yang,Chaofei Ji,Yunjun Xu,Haojie Lu,Chaowei Lu,Qingbing Hou,Yonghong Song,Dongquan Liu,Baoqiang Cao,Yang Lu
Despite laparoscopic-guided minimally invasive hepatectomy emerging as the primary approach for resecting hepatocellular carcinoma (HCC), there's still a significant gap in suitable biomaterials that seamlessly integrate with these techniques to achieve effective hemostasis and suppress residual tumors at the surgical margin. Electrospun films are increasingly used for wound closure, yet the employment of prefabricated electrospun films for hemostasis during minimally invasive HCC resection is hindered by prolonged operation times, complexity in implementation, limited visibility during surgery, and inadequate postoperative prevention of HCC recurrence. In this study, we integrated montmorillonite-iron oxide sheets into the PVP polymer framework, enhancing the resulting electrospun polyvinylpyrrolidone (PVP) /montmorillonite-iron oxide (MI) film (abbreviated as PMI) with robustness, hemostatic capability, and magnetocaloric properties. In contrast to the in vitro prefabricated electrospun films, the electrospun PMI film is designed to be formed in situ on liver wounds under laparoscopic guidance during hepatectomy. This design affords superior wound adaptability, facilitating meticulous wound closure and expeditious hemostasis, thereby simplifying the operative process and ultimately alleviating the workload of healthcare professionals. Moreover, when exposed to an alternating magnetic field, the film can efficiently ablate residual tumors, significantly augmenting the treatment efficacy of HCC. This article is protected by copyright. All rights reserved
研究领域:
生物医学工程
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肿瘤学
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外科手术
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产品关联
DOI
PubMed
高影响因子
Surfaces and Interfaces
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2024
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IF 5.7
Xuan Chen,Changmei Wu,Wei Luo,Long Li,Lan Xie,Bai Xue
Developing an ultra-thin flexible polymer film with simultaneously excellent electromagnetic interference (EMI) shielding performance and satisfactory mechanical property is still urgently demanded but challenging for integrated and miniaturized electronics. Herein, alternating multilayered silver nanowire-coating polyvinyl alcohol/ferroferric oxide@silver nanowires (PVA/Fe 3 O 4 @AgNW) composite films were successfully fabricated through spraying AgNWs on electrospinning PVA/Fe 3 O 4 films, followed by hot pressing the alternately stacked monolayer PVA/Fe 3 O 4 and PVA/Fe 3 O 4 @AgNW films in total of 6 layers. Stemming from superior conductive AgNW networks, alternating multilayered PVA/10-Fe 3 O 4 @10-AgNW composite film exhibits the prominent electrical conductivity of 1.5 × 10 5 S/m. Noteworthily, 6-layered PVA/10-Fe 3 O 4 @10-AgNW composite film with a thickness of 30 μm displays excellent EMI shielding effectiveness (SE) of 80.8 dB, on account of the unique alternating multilayered architectures and synergistic effect of conductive AgNWs and magnetic Fe 3 O 4 . Furthermore, 6-layered PVA/10-Fe 3 O 4 @10-AgNW film possesses satisfactory tensile strength (16.7 MPa) as well as superb flexibility (The fracture strain is 200.6 %). This effort sheds a new avenue for ultrathin flexible electrospinning films with both high EMI SE and remarkable flexibility, which has potential application in intelligent, wearable, and portable electronics.
研究领域:
材料科学
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电子工程
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产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
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2023
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IF 9.5
Chunhao Li,Ce Zhang,Ruisheng Zhao,Ning Zhao,Ruian Liu,Yang Zhang,Meilin Jia,Shuai Wang
Suitable relative humidity is essential for the preservation of cultural relics, food storage, and so on. A special material that can regulate the relative humidity in the microenvironment is particularly important. In this work, several innovative electrospun films with reversible photoresponsive wettability and the ability to regulate microenvironmental relative humidity were prepared. The spiropyran unit of the synthesized copolymer played the most important role in humidity regulation due to its reversible transition between a nonpolar ring-closed state and a polar ring-opened state induced by alternating ultraviolet/visible illumination. More interestingly, the introduction of acrylic acid segments exhibited a controllable hydrogen bond synergistic effect for increasing the range of humidity regulation. The color change and the reversible change ranges of wettability and microenvironmental relative humidity under ultraviolet/visible irradiation are all closely related to the number of acrylic acid segments. Cassie theory, density functional theory (DFT), and interaction region indicator (IRI) analysis were used to characterize this phenomenon. Electrospinning is a promising method to achieve large-scale production that can put such material into practical applications.
研究领域:
材料科学
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环境科学
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产品关联
DOI
PubMed
高影响因子
Food Chemistry-X
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2025
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IF 8.2
JinTao He,YingTing Liu,SuXuan Xia,Jing Deng,Wen Li,QinLu Lin,FeiFei Zhong,XiaoXi Zeng
Petroleum-based plastics dominate the fruit packaging market, but the microplastics migration poses ecological and health risks. This study developed an active packaging by electrospun polylactic acid (PLA) with sugarcane bagasse-derived nanocellulose (NC) and natural antimicrobial agent paeonol (Pae), providing a sustainable solution for extending shelf life. The films were optimized and characterized by SEM, FTIR, WCA, TGA, DSC, and mechanical properties. The results showed that NC significantly improved the mechanical properties of films (The tensile strength was 2.77 ± 0.49 MPa, and the elongation at break was 171.81 ± 5.29 %). Pae exhibited release properties and showed antimicrobial effect against Escherichia coli and Staphylococcus aureus with MICs of 300 μg/mL and 500 μg/mL, also inhibited Penicillium spp., isolated from rotten red grapes. PLA/NC/Pae film effectively slowed decay and extended the shelf life of red grapes by 2–3 days. This work provided a green strategy for converting agricultural waste into high-performance food packaging.
研究领域:
食品包装
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高分子科学
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纳米技术
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农业废弃物利用
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抗菌材料
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食品保鲜
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产品关联
DOI
PubMed
高影响因子
ChemSusChem
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2025
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IF 6.6
Mengzhen Yan,Siyi Jia,Weifeng Liu,Dongjie Yang,Xueqing Qiu,Jiahui Mo,Yukang Fan,Jingpeng Zhou,Fengshan Zhang
Graphical A polyvinyl alcohol/sodium lignosulfonate/polypyrrole (PVA/LS/PPy) composite film is fabricated by the in-situ polymerization of PPy onto the surface of PVA/LS electrospun film. LS significantly enhance the adsorption force between electrospun fibers and PPy, ensuring the uniform distribution of PPy, thereby giving high conductivity and exceptional electrochemical performance. The capacitance of the composite film is significantly improved by a stacking method. Flexible, highly conductive, and finely structured conductive materials hold significant promise for applications in flexible supercapacitors. However, the loading effect of conductive active substances and structural design remain critical factors that limit the performance of flexible conductive materials. In this study, polyvinyl alcohol/sodium lignosulfonate (PVA/LS) electrospun films are fabricated and polypyrrole (PPy) particles are loaded onto the surface of the electrospun fibers through in-situ polymerization. By leveraging the abundant sulfonic acid groups in LS, the adsorption force between electrospun fibers and PPy is significantly enhanced. This enhancement ensures the formation of uniform and continuous PPy shell that endows the electrospun film with high conductivity and exceptional electrochemical performance. Furthermore, a stacking method is employed to transform the PVA/LS/PPy film into a three-dimensional thick structure, which significantly increases the areal capacitance. With four layers of stacking, the areal capacitance of the symmetric solid-state supercapacitor assembled by 4(PPy6) reaches 2629.65 mF cm −2 , which is an impressive increase by a factor of 4.64 compared to the single-layer PPy6. This work presents a simple yet effective approach for preparing self-supporting flexible conductive materials with fine microstructures. Consequently, it provides valuable insights for performance improvement of flexible energy storage devices.
研究领域:
材料科学
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电化学
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纳米技术
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能量存储
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高分子科学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2021
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IF 8.128
Mengna Li,Na Li,Weiwang Qiu,Qian Wang,Jie Jia,Xueli Wang,Jianyong Yu,Xiaoran Li,Faxue Li,Dequn Wu
Infected wounds show delayed and incomplete healing processes and even render patients at a high risk of death due to the formed bacterial biofilms in the wound site, which protect bacteria against antimicrobial treatments and immune response. Nitric oxide based therapy is considered a promising strategy for eliminating biofilms and enhancing wound healing, which encounters a significant challenge of controlling the NO release behavior at the wound site. Herein, a kind of phenylalanine based poly(ester urea)s with high thermal stability are synthesized and fabricated to electrospun films as NO loading vehicle for infected wound treatment. The resultant films can continuously and stably release nitric oxide for 360 h with a total concentration of 1.15 μmol L −1 , which presents obvious advantages in killing the bacteria and removing biofilms. The results exhibit the films have no cytotoxicity and may accelerate the wound repair without causing inflammation, hemolysis, or cytotoxic reactions as well as stimulate the proliferation of fibroblasts and increase the synthesis of collagen. Therefore, the films may be a suitable NO releasing dressing for removing biofilms and repairing infected wounds.
研究领域:
材料科学
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生物医学工程
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伤口愈合
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药学
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）