LANGMUIR
·
2023
·
IF 3.9
Soumia Cheddah,Zihang Xia,Yan Wang,Chao Yan
To boost the implementation of colloidal crystals (CCs) in separation science, the effects of the most common chromatographic reversed phases, that is, butyl and octadecyl, on the assembly of silica particles into CCs and on the optical properties of CCs are investigated. Interestingly, particle surface modification can cause phase separation during sedimentation because the assembly is highly sensitive to minute changes in surface characteristics. Solvent-induced surface charge generation through acid–base interactions of acidic residual silanol groups with the solvent is enough to promote colloidal crystallization of modified silica particles. In addition, solvation forces at small interparticle distances are also involved in colloidal assembly. The characterization of CCs formed during sedimentation or via evaporative assembly revealed that C4 particles can form CCs more easily than C18 particles because of their low hydrophobicity; the latter can only form CCs in tetrahydrofuran when C18 chains with a high bonding density have extra hydroxyl side groups. These groups can only be hydrolyzed from trifunctional octadecyl silane but not from a monofunctional one. Moreover, after evaporative assembly, CCs formed from particles with different surface moieties exhibit different lattice spacings because their surface hydrophobicity and chemical heterogeneity can modulate interparticle interactions during the two main stages of assembly: the wet stage of crystal growth and the late stage of nano dewetting (evaporation of interparticle solvent bridges). Finally, short, alkyl-modified CCs were effectively assembled inside silica capillaries with a 100 μm inner diameter, laying the foundation for future chromatographic separation using capillary columns.
研究领域:
材料科学
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分离科学
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DOI
PubMed
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2017
·Vol. 134
·期 20
·
IF 1.86
Zhou Zhu,Wanli Kang,Bauyrzhan Sarsenbekuly,Hongbin Yang,Caili Dai,Runmei Yang,Haiming Fan
An amphiphilic polymer with twin-tailed hydrophobic groups was prepared by micellar polymerization of acrylamide as hydrophilic monomers, 2-acryloylamino-2-methyl-1-propanesulfonic acid as functional monomers and N , N -dodecyl acrylamide as hydrophobic monomers. Using the same method, containing single-tailed hydrophobic group of the amphiphilic polymer and not containing the hydrophobic group of ordinary polymer were prepared. The molecular structure of the product was characterized by infrared spectrum and 1 H nuclear magnetism resonance spectrum. By inclusion complexation of β-cyclodextrin (β-CD), the hydrophobic association on the apparent viscosity contribution rate was studied. Relationship between hydrophobic group structure and its performance was investigated by the rotational viscometer, scanning electron microscopy (SEM), fluorescence spectroscopy, and rheometer. The results showed that amphiphilic polymers containing twin-tailed hydrophobic groups had a lower critical aggregation concentration (CAC). When the amphiphilic polymer concentration was higher than CAC, hydrophobic association was stronger, which led to a higher apparent viscosity contribution rate. At the same polymer solution concentration, amphiphilic polymer containing twin-tailed hydrophobic group had better performance on temperature resistance, salt tolerance, and mechanical shear resistance compared with the other two polymers. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017 , 134 , 44744.
研究领域:
高分子化学
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材料科学
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DOI
高影响因子
Journal of Cleaner Production
·
2019
·
IF 6.395
Yongzhi Liu,Huaili Zheng,Yongjun Sun,Jie Ren,Xinyu Zheng,Qiang Sun,Shaojie Jiang,Wei Ding
Natural polymeric flocculants as sludge conditioners have received great attention due to their non-toxic and biodegradable advantages. However, the application of amphiphilic natural flocculants as sludge conditioners is rarely reported. In this work, the novel chitosan-based flocculants (CS-g-PAO) with amphiphilic structure were synthesized by ultraviolet light initiated method for the enhancement of sludge dewatering performance. The solubility of CS-g-PAO was significantly improved in a wide pH range (2.0–10.0). Various characterization methods were used to investigate the structure, thermal stability and surface morphology of copolymers , suggesting the successful synthesis of CS-g-PAO. In dewatering experiments, CS-g-PAO showed superior dewatering performance, and filter cake moisture content could be decreased to 77.98% from 95.14%. Moreover, the results of extracellular polymeric substances (EPS) components indicated that hydrophobic effect of CS-g-PAO was beneficial to remove the protein in S-EPS and TB-EPS, which had the crucial influence on dewatering performance. Furthermore, the dewatering mechanism was discussed based on the effects of zeta potential , apparent viscosity , surface tension and flocs structure on dewaterability. Results revealed that CS-g-PAO had strong hydrophobic association effect and surface activity. In addition, enhanced charge neutralization and hydrophobic interaction played a synergetic role in improving the dewaterability of CS-g-PAO.
研究领域:
环境科学
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材料科学
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DOI
高影响因子
JOURNAL OF SEPARATION SCIENCE
·
2022
·Vol. 45
·期 15
·2946-2955
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IF 3.614
Mengting Li,Dongqiang Lin,Shanjing Yao,Qilei Zhang
Molecular interactions between ligands and target biomolecules are crucial in the development of chromatographic techniques for the separation and purification of biotherapeutics. In this study, the role of functional moieties on a mixed-mode ligand (phenylalanine-tyrosine-glutamate-5-aminobenzimidazole) for human immunoglobulin G purification was investigated and a detailed mechanism was discussed. A similar ligand with glutamic acid substituted by glutamine (phenylalanine-tyrosine-glutamine-5-aminobenzimidazole) together with other resins including a commercial resin (CM Bestarose Fast Flow), phenylalanine-tyrosine-glutamate, glutamate-5-aminobenzimidazole, and 5-aminobenzimidazole resins were prepared for comparison. Molecular dynamics simulation and experimental studies were used to analyze the difference between these ligands. The results showed that the carboxyl group of phenylalanine-tyrosine-glutamate-5-aminobenzimidazole contributed 70% of the electrostatic interaction during human immunoglobulin G binding, and 5-aminobenzimidazole provided electrostatic repulsion for desorption, which showed low selectivity and binding capacities at pH 4.0 (dynamic binding capacities at 10% breakthrough of human immunoglobulin G = 1.0 mg/ml resin, dynamic binding capacities at 10% breakthrough of human serum albumin = 1.2 mg/ml resin) when used as an individual resin ligand. The results showed in this study demonstrated that it is possible to achieve optimal antibody separation and purification through reasonable ligand design by understanding the performance of key functional moieties in binding and elution processes.
研究领域:
生物化学
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生物分离技术
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DOI
PubMed
高影响因子
JOURNAL OF MOLECULAR LIQUIDS
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2024
·
IF 5.3
Yuxi Lu,Lei Huang,Wen Chen
Fatty acid surfactants, known for their cost-effectiveness and efficacy, are commonly used in the flotation process of hematite. An in-depth understanding of the role of hydrophobic groups on the performance of fatty acid surfactants can enhance and guide the utilization of surfactants for hematite flotation. Herein, four representative fatty acid surfactants with heterogeneous hydrophobic groups were selected and the influences of the hydrophobic group configuration on the adsorption behavior and flotation performance were systematically investigated by density functional theory (DFT) calculations, quantitative structure–activity relationship (QSAR) analyses, surface tension measurements, wettability tests and molecular simulations. The results of the DFT calculation and QSAR analysis reveal that logP is the primary parameter in determining the collective power of fatty acid surfactants for hematite. The results of the steric hindrance study suggest that the fatty acid with a cyclic hydrocarbon structure forms an L-shaped arrangement on mineral surface. This arrangement increases the intermolecular steric hindrance effects and reduces the coverage density. Compared to the l-shaped arrangement of fatty acids with straight hydrocarbon chains, the L-shaped arrangement possesses better selectivity towards hematite. The results of the flotation tests indicate that fatty acids with straight hydrocarbon chains possess a strong collection ability to hematite, while fatty acids with circular structures exhibit enhanced selectivity, providing experimental support for the adsorption model. This work provides a scientific approach to better understand the structure–activity relationship of surfactants in flotation, with implications for the development of effective surfactants for hematite.
研究领域:
矿物加工工程
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表面化学
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DOI
高影响因子
JOURNAL OF SURFACTANTS AND DETERGENTS
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2021
·Vol. 24
·期 6
·923-931
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IF 1.902
Yun Li,Danyang Sun,Chenhui Jiang,Haiyan Ding,Quanjie Wang
Polypeptide surfactants with different lengths of hydrophilic groups and lipophilic groups were synthesized from collagen hydrolysate polypeptides by the Schotten-Baumann reaction. Collagen hydrolysate polypeptides were prepared through alkaline hydrolysis of chromium-containing leather wastes, followed by changing the molecular weight of the collagen hydrolysate and the carbon chain length of the acid chloride. Fourier transform infrared spectroscopy, confirmed the successful synthesis of the polypeptide surfactants. Furthermore, surface activities of surfactants were tested to reflect the influence of the length of hydrophilic and lipophilic groups on properties, such as surface tension, foamability, foam stability, wettability, and Hydrophile–Lipophile Balance value. The results indicated that for surfactants prepared from collagen hydrolysate, a shorter hydrophilic group length resulted in lower surface tension and better foamability, foam stability, and a wetting ability which indicates the surfactants can be used as wetting agents. In contrast, the surfactant with a greater lipophilic group length had lower surface tension and poorer foamability, foam stability, and wetting ability. The presence of the C=C bond of the oleoyl lipophilic group decreased surface tension. The polypeptide surfactants prepared from collagen hydrolysate not only can effectively utilize chromium-containing leather solid waste produced, but also avoid environmental pollution and promote the sustainable development of the leather industry.
研究领域:
生物化学
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环境科学
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皮革工业
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DOI
高影响因子
MATERIALS CHEMISTRY AND PHYSICS
·
2017
·
IF 2.084
Qiang Su,Lijie Duan,Meifang Zou,Xuetong Chen,Guang Hui Gao
Polyacrylamide (PAAm) and polyacrylic acid (PAAc) hydrophobic association hydrogels were synthetized via free radical polymerization , respectively. Also, the hydrophobic alkyl groups were introduced into PAAm and PAAc to enhance the mechanical properties of hydrogels. It was found that PAAm and PAAc hydrophobic association hydrogels didn't exhibit any self-healing behaviors. When PAAm and PAAc samples were touched each other for a few seconds, however, PAAm hydrophobic association hydrogels exhibited a strong adhesive force with PAAc hydrophobic association hydrogels. Subsequently, the adhesive behavior between PAAm and PAAc hydrophobic association hydrogels was investigated. It indicated that the adhesion between PAAm and PAAc hydrophobic association hydrogels was based on hydrogen bonding between amide groups of PAAm and carboxyl groups of PAAc. Moreover, the hydrophobic groups also had the cooperative function to enhance the adhesive strength of PAAm/PAAc adhesive hydrogels via hydrophobic association. It was envisioned that more adhesive hydrogels would be developed in the future and more applications would be possibly achieved in repairing tissue engineering or interface.
研究领域:
材料科学
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高分子化学
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生物医学工程
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DOI
高影响因子
Journal of Materials Chemistry A
·
2021
·Vol. 9
·期 7
·4193-4202
·
IF 12.732
Xiaoli Wu,Xulin Cui,Qi Wang,Jingtao Wang,Wenjia Wu,Wenpeng Li,Zhongyi Jiang
Two-dimensional (2D) lamellar membranes with well-defined channels show great promise in molecular separation. The mass transfer paths include both interlayer and cross-layer channels; however, previous studies mainly focused on interlayer channels. Herein, g-C3N4 nanosheets with various lateral sizes and thicknesses were edge-functionalized by hydrophilic (–OH) or hydrophobic (–OOCCH3) groups and utilized as building blocks for lamellar membranes. In this way, the hydrophilicity, length, and thickness of cross-layer channels were subtly tuned. We demonstrated that the cross-layer channels display a ‘gate effect’ to govern molecular selectivity while the interlayer channels determine the molecular transport rate. Membranes with hydrophilic/hydrophobic heterostructured channels acquire highly elevated polar solvent permeance and polar/nonpolar solvent selectivity, and this ‘gate effect’ can be intensified by increasing the thickness and total length of the cross-layer channels. The acetonitrile permeance and acetonitrile/toluene separation factor reach as high as 2128 L m−2 h−1 bar−1 and 12.7, respectively. This study may represent the first example to identify the contribution of cross-layer channels within lamellar membranes, paving a way to designing efficient 2D nanochannel membranes.
研究领域:
材料科学
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化学工程
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纳米技术
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产品关联
DOI
高影响因子
JOURNAL OF DAIRY SCIENCE
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2023
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IF 3.5
Ru Zhao,Wenfei Fu,Dan Li,Chao Dong,Zhaoxue Bao,Cuina Wang
ABSTRACT Three modifications (pH-shift, ultrasound, combined pH-shift/ultrasound) induced alterations in pure whey protein (WPI), pea protein (PPI), and mixed whey/pea protein (WPI/PPI) were investigated. The processing effect was related to the protein type and technique utilized. Solubility of WPI remained unchanged by various treatments. Particle size was enlarged by pH-shift while reduced by ultrasound and combined approach. All methods exposed more surface hydrophobic groups on WPI, while pH-shift and joint processing was detrimental to its emulsifying activity. PPI and mixture exhibited similar responses toward the modifications. Solubility of PPI and the blend enhanced in the sequence of pH-shift/ultrasound > ultrasound > pH-shift. Individual approach expanded while co-handling diminished the particle diameter. Treatments also caused more disclosure of hydrophobic regions in PPI and WPI/PPI and emulsifying activity was ameliorated in the order of pH-shift/ultrasound > ultrasound > pH-shift.
研究领域:
食品科学
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蛋白质化学
·
超声波技术
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DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Changjian Zhou,Hailang Liu,Tong Liu,Yusheng Wu,Wanrong Chen,Zhengqing Ding,Xinyan Yan,Xujuan Huang,Zhaosheng Cai
Emulsifiers based on amphiphilic cellulose are typically created by adding a hydrophobic group to hydrophilic cellulose. There are few reports on the use of rigid large skeleton structures as hydrophobic groups in the modification of hydrophilic cellulose. This study investigated the hydrophobic rosin (DAGE, containing a large rigid hydrogenated three-phenanthrene ring) modified hydroxyethyl cellulose (HEC), and it was applied to stabilize emulsion gels as an emulsifier (DAGE-g-HEC). DAGE-g-HEC was successfully prepared and DAGE-g-HEC (I–V) were obtained with different grafting degrees ranging from 34.65 % to 46.20 %. In terms of lowering water surface tension, DAGE-g-HEC demonstrated greater activity than HEC, and the γ CMC was about 36.00 mN/m. DAGE-g-HEC stabilized emulsion gels with 80 % oil phase showed that emulsion stability remained for more than six months at 0.05 wt% or above 0.05 wt% DAGE-g-HEC concentration due to the tight interfacial films established by the rigid group of rosin. The rheological property showed that as the DAGE-g-HEC concentrations rose, so did the emulsions' apparent viscosity. All emulsion gels exhibit strong elastic behavior, according to the loss tangent (tan δ = G″/G′) evolutions.
研究领域:
高分子化学
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胶体与界面科学
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食品科学
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材料科学
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化学工程
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
·
2024
·
IF 3.3
Huiyun Zhang,Xinling Li,Ziye Zhang,An Jiang,QiaoQiao Bai
BACKGROUND Previous studies have demonstrated that the addition of chitosan can improve the quality and functional properties of meat products. However, the underlying mechanism remains unclear. In this study, the effect and mechanism of the addition of chitosan on the gel properties of myofibrillar protein (MP) were investigated. RESULTS The results indicated that the gel strength and the water-holding capacity of MP-chitosan gel increased significantly when chitosan was added at 2.5–10 mg mL −1 . Myofibrillar protein samples with 10 mg mL −1 added chitosan exhibited the highest elasticity and viscosity during gel formation and strengthening. The addition of chitosan also caused a modification in both the secondary and tertiary structure of MP, resulting in an enhanced exposure of hydrophobic and sulfhydryl groups in comparison with the control. Chitosan inhibited the conversion of immobilized water into free water and the formation of water channels during the thermal gelation process of MP. The denaturation enthalpy ( Δ H) of myosin decreased as the concentration of chitosan exceeded 5 mg mL −1 . The microstructure showed that the incorporation of chitosan (5–10 mg mL −1 ) facilitated the formation of compact and well organized MP gel networks. CONCLUSION The addition of chitosan can enhance the functional properties of meat protein and facilitate heat-induced gelation, making it a promising ingredient for improving the quality of processed meat products. © 2024 Society of Chemical Industry.
研究领域:
食品科学
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蛋白质化学
·
生物物理学
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产品关联
DOI
PubMed
高影响因子
ACS Sensors
·
2022
·
IF 9.618
Zishuo Zhang,Yuanyuan Wang,Ziyin Mei,Yiming Wang,Hui Li,Shaoguang Li,Fan Xia
Continuous real-time measurement of specific targets in complex biological samples is of great significance for early diagnosis and treatment of diseases and thus enables achievement of personalized medicine. Electrochemical aptamer-based (E-AB) sensors are good candidates to fill this role due to their high specificity, sensitivity, rapid detection, and simple preparation. However, this sensor class suffers from severe baseline drift in the complex matrix probably due to the nonspecific adsorption of components. Here, we introduce a series of self-assembled monolayers with a variety of hydrophobic functional groups into an E-AB sensor platform, achieving enhancement of the antifouling performance and thus the detection performance (e.g., stability, sensitivity, and specificity). We reveal that the antifouling performance enhanced by such hydrophobic SAMs is probably due to its instant adsorption of components onto the surface, rather than the repelling of these components by hydrophilic SAMs in previous reports.
研究领域:
生物传感器
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分析化学
·
生物医学工程
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）