SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2016
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IF 2.653
Xue-Dong Xiao,Lin Shi,Li-Hui Guo,Jun-Wen Wang,Xiang Zhang
The supramolecular interaction between the water-soluble pillar[5]arene (WP[5]) as host and dopamine hydrochloride (DH) as guest was studied by spectrofluorometry . The fluorescence intensity of DH gradually decreased with increasing WP[5] concentration, and the possible interaction mechanism between WP[5] and DH was confirmed by 1 H NMR, 2D NOESY , and molecular modelling. Based on significant DH fluorescence, a highly sensitive and selective method for DH determination was developed for the first time. The fluorescence intensity was measured at 312 nm, with excitation at 285 nm. The effects of pH, temperature, and reaction time on the fluorescence spectra of the WP[5]-DH complex were investigated. A linear relationship between fluorescence intensity and DH concentration in the range of 0.07–6.2 μg mL − 1 was obtained. The corresponding linear regression equation is Δ F = 25.76 C + 13.56 (where C denotes the concentration in μg mL − 1 ), with the limit of detection equal to 0.03 μg mL − 1 and the correlation coefficient equal to 0.9996. This method can be used for the determination of dopamine in injection and urine samples. In addition, the WP[5]-DH complex has potential applications in fluorescent sensing and pharmacokinetics studies of DH.
研究领域:
分析化学
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超分子化学
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药物代谢
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生物分析
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药代动力学
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DOI
高影响因子
ACS Nano
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2025
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IF 16
Shujie Li,Houde Wu,Li Guo,Xiaoyi Wang,Gang Shu,Xinxing Li,Shao-Kai Sun
Achieving high resolution while minimizing contrast agent dosage remains a key goal, yet a major challenge in contrast-enhanced computed tomography (CT) imaging. Herein, we propose an artificial intelligence-assisted low-dose high atomic number contrast agent for ultrahigh-resolution CT imaging. As a proof of concept, high-quality PEGylated hafnium oxide nanoparticles (DA-HfO2 NPs) are synthesized, exhibiting superior X-ray attenuation, high hafnium content (36%), excellent water solubility, appropriate hydrodynamic size (13.5 nm), and prolonged circulation half-life (161.9 min). High-dose DA-HfO2 NPs enable extended ultrahigh-resolution vascular imaging with a spatial resolution of 0.15 mm and a time window of at least 60 min. More importantly, by integrating artificial intelligence, the low-dose contrast agent (at 25% of the standard dose) achieves imaging quality comparable to that of the high-dose agent in both contrast density and spatial resolution, while simultaneously enhancing biosafety. This strategy enables high-resolution imaging at reduced contrast agent doses and offers a promising approach for sensitive and safe CT angiography.
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PubMed
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Advanced Healthcare Materials
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2025
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IF 9.6
Meizhen Zhou,Jing Zhu,Dongyun Zhang,Jianping Dou,Wenqi Chen,Yi Zhang,Xiaopeng Gao,Jixi Zhang,Ping Liang,Jie Yu
Reactive Oxygen Species (ROS) exhibit a paradoxical dual role in tumor therapy. Tumor hypoxia restricts therapeutic ROS generation, while excessive secondary ROS post-ablation suppresses T-cell function yet promotes M1 macrophage polarization. Semiquinone radical-doped reduced polydopamine nanoparticles (PDA red ) loaded is developed with resiquimod (R848) (PDA red @R848) via π–π stacking. Reduction enriches the nanoparticles with semiquinone radicals, enhancing dielectric properties and dipole polarization under electromagnetic effects. This nanoparticle enables the specific hydrogen radicals (H•)/ROS generation in oxygen-heterogeneous tumor under microwave irradiation. In microwave dynamics therapy (MDT) phase, PDA red converts protons (H⁺) to H• under microwave irradiation in hypoxic regions, targeting cytochrome c and inducing tumor cell apoptosis and immunogenic cell death; PDA red establishes an internal electric field under microwave, facilitating electron–hole separation to produce ROS and trigger ferroptosis in normoxic regions. In post-MDT phase, PDA red ’s intrinsic polyphenols scavenge excess secondary ROS produced by damaged cells, alleviating immunosuppression. Compared with blank control, PDA red @R848 increased CD4⁺/CD8⁺ T-cell infiltration (6.4-fold) and M1 macrophage polarization (2.5-fold M1/M2 ratio elevation). Pro-inflammatory cytokines are significantly reduced, and tumor volume is suppressed by 94.8%. This study proposes an innovative dual-action mechanism coordinating oxygen-adapted radical generation with secondary ROS clearance to reprogram redox/immune homeostasis for effective liver tumor eradication.
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PubMed
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Advanced Healthcare Materials
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2025
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IF 9.6
Huanhuan Wu,Haoyu Wang,Jinwen Wei,Gang Shu,Shao-kai Sun,Cai Zhang,Dong Li
Acquiring multidimensional tumor and tumor-associated vascular information is essential for accurate diagnosis and treatment planning of glioma, yet effective imaging methods are still lacking. Here, ultrasmall manganese ferrite nanoparticles (UMFNs) are developed as a dual contrast-enhanced T 1 -weighted imaging (T1WI) and susceptibility-weighted imaging (SWI) probe for multidimensional diagnosis of glioma. The UMFNs are synthesized through thermal decomposition and functionalized with polyethylene glycol, ensuring excellent water dispersibility and biocompatibility. Characterization studies confirm the nanoparticles’ uniform size (3.8 nm) and high stability in various media. High r 1 (6.8 m m −1 s −1 ) and r 2 * (95.1 m m −1 s −1 ) values demonstrate the superior T 1 and T 2 * enhancement capabilities of UMFNs. In vivo imaging on a 3.0 T magnetic resonance imaging (MRI) scanner demonstrates that UMFN-enhanced SWI clearly delineates tumor margins and provides sustained tumor enhancement in ultrasmall orthotopic glioma (<2 mm). Besides, UMFN-enhanced SWI reveals distinct vascular structures associated with the glioma, including tortuous, thickened vessels indicative of tumor-induced angiogenesis. Whole-brain histological analysis corroborates these findings, demonstrating dense tumor proliferation and vascular remodeling. These results highlight the potential of UMFNs as a dual-enhanced agent for the early detection and high-resolution vascular mapping of glioma, providing an advanced multidimensional method for precise diagnosis of brain tumors.
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PubMed
高影响因子
LANGMUIR
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2025
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IF 3.9
Pengshu Xie,Chuanliang Chen,Ke Tian,Minhan Cheng,Qianyang Li,Hua Deng
The development of efficient and sustainable solar-driven water evaporation systems is crucial for mitigating global water scarcity. However, the intermittent nature of solar radiation presents a major challenge for achieving continuous steam generation under all conditions. Most current fabrication methods for solar evaporators lack scalability, flexibility, and environmental compatibility. Herein, we present a scalable-fabricated solar evaporator with a gradient-heating design, constructed from PET/CNT/PDA/CNC@CuS composites for continuous steam generation. This device synergistically utilizes solar illumination and electrical heating, enabled by the strong broadband light absorption and excellent electrical conductivity imparted by a two-step spray-coating of carbon nanotubes (CNT) and CuS-decorated cellulose nanocrystals (CNC@CuS). Cellulose nanocrystals (CNC) are used to uniformly load commercial CuS powder onto CNT/PDA-coated PET fabric via electrostatic and hydrogen-bond interactions. Synergistic effect combining 1-sun illumination and 5 V input elevates the evaporation rate to 5.49 kg m–2 h–1, with temperature surpassing individual modes by 6.8 °C (light-only) and 4.2 °C (electricity-only). The evaporator demonstrates remarkable salt tolerance, maintaining 5.3 kg m–2 h–1 in 3.5 wt % NaCl (1-sun and 5 V) and 2.3 kg m–2 h–1 (only 5 V), with no performance decline over 7 days. Furthermore, the CNC@CuS coatings also impart intrinsic antibacterial and UV-shielding properties. This study provides a promising approach for environmentally friendly, efficient, and all-weather seawater desalination.
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Small Structures
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2025
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IF 11.3
Jiugang Li,Haoran Qiao,Wenqi Zhang,Zhiqiang Wang,Ruiyan Wu,Yi Hu,Kerun Hua,Wenbin Li,Jiahao He,Jiuyi Li
Solar interfacial evaporation holds significant promise for sustainable desalination, but its long-term performance and practical deployment are often hindered by salt accumulation and maintenance requirements. To overcome these limitations, a cotton fabric MoS 2 composite is synthesized by applying a MoS 2 /dopamine mixture dissolved in water–alcohol solution onto cotton fabrics. This composite is engineered into a dual-interface symmetrical-structure solar fabric evaporator (DS-SFE) with self-cleaning and salt-removal capabilities, enabling efficient evaporation of high-salinity brine. DS-SFE achieves 95.5% solar absorption and 40.0 kg m −2 water supply flux. Under 1 sun illumination, the evaporation rate in deionized water reaches 2.25 kg m −2 h −1 . Even in a 15 wt% NaCl solution, stable and excellent evaporation performance (1.75 kg m −2 h −1 ) can still be maintained. The flip-design establishes easy operation in extreme salinity (20 wt% NaCl), requiring only manual rotation every 8 h to clear accumulated salt and ensure continuous operation. This work advances eco-friendly solar evaporator design, demonstrating scalable potential for sustainable water purification.
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高影响因子
ACS Applied Materials & Interfaces
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2025
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IF 8.2
Leyu Dai,Zhichao Zhou,Yingjie Chang,Zhaoxuan Liu,Jun Sun,Chuanxiang Qin,Jianjun Wang,Lixing Dai
A strain sensor with high sensitivity and a wide working range is urgently required owing to its potential applications in wearable electronic devices. Nevertheless, high sensitivity, which includes a high gauge factor (GF) and a low detection limit, requires a noticeable structural variation even at a tiny deformation, while a wide working range requires maintaining morphological integrity under a large strain. The contradictory performances lead to a huge challenge to simultaneously acquire the aforementioned comprehensive performance. Herein, we prepared a twisted fiber-based strain sensor (TFSS) composed of a thermoplastic polyurethane (TPU)/silver nanoparticle (AgNP) fiber and a TPU/carbon nanotube (CNT) fiber. The special twisting structure and the synergistic effect of the different conductive materials endow TFSS with a high GF of 1.05 × 105 within a strain range of 250 ∼ 300%, ultralow detection limit (0.02% strain), large detection range (up to 300% strain), short response time (60 ms), and excellent sensing stability and durability (4000 stretching/releasing cycles under 50% strain). Moreover, the strain sensor can be used for diverse human movement recognition, microexpression detection, pulse/breath monitoring, and speech recognition, offering a promising strategy for designing high-performance and smart wearable devices.
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JOURNAL OF HAZARDOUS MATERIALS
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2025
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IF 11.3
Hongshan Jia,Xinyue Duan,Jie Liu,Fei Zhu,Yinlong Li,Jing Yang,Yuxing Han,Yingqing Zhan
The practical application of hydrogel-based polymer membranes in separating emulsified oily wastewater is hindered by their dynamic interfacial instability and insufficient inherent self-cleaning capacity. Herein, the polyvinyl alcohol-tannic acid (PVA-TA) hydrogel decorated polyacrylonitrile (PAN) nanofiber composite membrane with super-wetting and photothermal-catalytic self-cleaning features was constructed via hydrogen bond crosslinking and nano-reinforcement of thorn ball-like Bi 19 Br 3 S 27 -PDA-Bi 4 O 5 Br 2 core@double-shell nanohybrid (BB@PAN). The oil repellence test, density functional theory calculation, and molecular dynamics simulation verified the super-wettable and ultra-low oil adhesion behavior of BB@PAN composite membrane, resulting in highly efficient separation of oil-in-water emulsions (Flux: 1943–2626 L m −2 h −1 , oil rejection rate: 99.19–99.57 %). Owing to the nano-enhancement and multiple hydrogen bonds, the BB@PAN membrane retained its structural integrity and separation stability under extreme conditions. The broad-spectrum response and high light absorption efficiency of 3D core@double-shell structure (BOB-PDA-BBS) endowed the membrane with efficient photothermal conversion (temperature reached 62.56 °C within 24 min), enabling rapid volatilization of adhered light oils and effectively preventing a decline in permeation flux. With the support of PDA-mediated electron transfer bridge, the BB@PAN composite membrane achieved outstanding photocatalytic self-cleaning efficiency, as evidenced by its high degradation rate for various dyes. Therefore, the photothermal-catalytic double-mode self-cleaning mechanism tremendously addresses the complicated membrane fouling issues caused by oils and organic pollutants.
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DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2025
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IF 9.7
Longyu Wang,Yiming Zhang,Chengyu Zhang,Fabrice Ndayisenga,Xiangyang Wang,Renyuan Zhao,Zhisheng Yu
The alkaline hydrogen evolution reaction (HER) plays a crucial role in advancing sustainable hydrogen production technologies. However, the limited abundance and reactivity of interfacial water molecules significantly hinder the reaction kinetics. This research develops a WC x -supported PtNi alloy (PtNi/WC x ) catalyst to reorganize the hydrogen-bond arrangement of interfacial water by adjusting electron density at metal sites. In situ Raman coupled with ab initio molecular dynamics (AIMD) is employed to investigate how the interfacial hydrogen-bond network influences catalytic activity. These results demonstrate that the electron-rich Pt sites in PtNi/WC x disrupt the hydrogen-bond network by altering the alignment of water molecules. This disruption enhances the mobility and reactivity of H 2 O* and OH* intermediates at the solid-liquid interface. The optimized PtNi/WC x catalyst achieves exceptional HER activity, requiring only 16 mV at 10 mA cm −2 and 78 mV at 100 mA cm −2 . These findings offer a microscopic perspective and theoretical guidelines for optimizing HER catalysts via interfacial water structure manipulation.
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高影响因子
Journal of Energy Storage
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2025
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IF 9.8
Zhuoni Jiang,Zhiqing Ge,Shuo Yan,Jingjing Shu,Mozhen Wang,Xuewu Ge
The synergistic integration of anti-fogging and air purification functionalities represents an emerging frontier in sustainable indoor environmental management. Herein, novel submicron magnetic phase-change microcapsules (MP-FS/Ag) were prepared through a multi-step fabrication strategy combining Pickering emulsification, hydrolytic polycondensation, and radiation reduction method. The MP-FS/Ag microcapsules have an average size of 400 nm, and feature a paraffin core (62.0 % paraffin encapsulation ratio) encapsulated within a hierarchically structured organic-inorganic composite shell comprising Fe 3 O 4 nanoparticles, fibrous silica, polydopamine (PDA), and silver nanoparticles (AgNPs). They can be uniformly and stably dispersed in polyvinyl alcohol (PVA) to form a transparent PVA composite film with a surface contact angle of 11.8 o . The high hydrophilicity endowed by polydopamine and PVA enables the film to achieve anti-fogging and self-cleaning properties through accelerated diffusion and absorption of condensed water, and effective formaldehyde degradation (87 % removal in 150 min) was achieved via AgNPs-enabled photocatalysis. In fact, the efficient thermal regulation and collaborative photothermal effect (94.8 % solar-thermal conversion efficiency) of MP-FS/Ag also conducive to the superior anti-fogging performance. The strong PDA-PVA interfacial interactions and the hierarchical shell architecture consists of PDA and AgNPs can guarantees the long-term structural stability of the composite film. This multifunctional system establishes a new paradigm for smart environmental management in confined spaces (e.g., vehicles, greenhouses), while providing design insights for advanced anti-fog optical devices. The magnetic retrievability and solar-responsive features further enhance practical applicability in circular economy frameworks.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
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2025
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IF 13.2
Li Wang,Mengyun Wang,Anhui Lin,Zhuozhen Qian,Yanfang Wu,Zhiyu Liu,Xiaomei Chen
Traditional methods for detecting foodborne pathogens rely on culture techniques, while advanced analytical instruments, though more sophisticated, are unsuitable for rapid detection and cannot eliminate residual contamination from secondary sources. In this study, a novel method integrating near-infrared light-induced upconversion fluorescence sensing with photothermal sterilization was developed for the detection of Vibrio parahaemolyticus ( V. parahaemolyticus ). Upconversion nanoparticles (UCNPs) were used as a fluorescence signal carrier, and silica-modified hollow polydopamine (PDA)-loaded Fe 3 O 4 @Au (HS-PDA@Fe 3 O 4 @Au) functioned as a photothermal element. Based on fluorescence resonance energy transfer (FRET) and photothermal effect, an electromagnetic-driven microfluidic fluorescence platform was constructed to achieve sensitive detection and in situ sterilization of V. parahaemolyticus . More importantly, the platform allows programmable control of the shuttling of magnetic materials within the functional compartments of the sensing chip. Under optimal experimental conditions, the detection limit for V. parahaemolyticus was 5 CFU/mL, and the linear range was 8–10 6 CFU/mL. Additionally, the sterilization rate reached 100 % after 8 min of 980 nm near-infrared irradiation, effectively eliminating the residual pathogenic bacteria and preventing secondary pollution. Therefore, the platform developed in this study demonstrates great potential for on-site detection of V. parahaemolyticus in seafood.
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高影响因子
MACROMOLECULAR RAPID COMMUNICATIONS
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2025
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IF 4.3
Zerong Hou,Chunyang Zhang,Haibo Wang,Fulin Huai,Dongzhi Yang,Lin Qiu,Jun Nie,Guiping Ma
Diabetic wounds (DWs) face challenges from persistent hyperglycemia, bacterial infection, and abnormal pH levels, which collectively impede healing. Traditional treatments, such as antibiotics and debridement, often show limitations such as drug resistance, pain, or high cost. To address this issue, a hybrid particle is developed based on in situ encapsulating glucose oxidase (GOx) in hydrogen-bonded organic framework HOF-101, enabling enzyme immobilization under mild conditions while preserving catalytic activity. The particle is formed through hydrogen bonding-triggered self-assembly and polydopamine coating and subsequently incorporated into a dual-network hydrogel matrix. The resulting composite hydrogel achieves efficient pH reduction and H 2 O 2 generation by consuming glucose, while exhibiting tunable photothermal responses under near-infrared (NIR) irradiation, thus enabling local microenvironment modulation and synergistic antibacterial effects. In addition, the hydrogel demonstrates favorable mechanical properties and biocompatibility. These results suggest its great potential for application in DW healing.
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高影响因子
危险品化学品经营许可证（带存储）