PETROLEUM CHEMISTRY
·
2024
·Vol. 64
·期 2
·297-308
·
IF 1.3
Han Yating,Xia Xia,Peng Zexuan,Xiao Yang
Abstract To address the limitations of the existing catalytic hydrogenation and sulfuric acid sulfonation intended to remove aromatic hydrocarbons from liquid paraffin oils, the adsorption method was chosen for the adsorptive separation of phenanthrene, a typical aromatic hydrocarbon, from liquid paraffin oils. A zeolite imidazolate framework-8 (ZIF-8) precursor was firstly prepared, and then ZIF-8-derived porous carbon (ZDPC) adsorbents were obtained using different temperatures of carbonization of the precursor under nitrogen atmosphere; these adsorbents were then used for the adsorption and separation of phenanthrene from liquid paraffin oils. The experiment showed that the maximum specific surface area of a ZDPC adsorbent could reach 1458 m 2 /g at 900°C. However, the total pore volume and adsorption capacity of ZDPC porous carbon were maximal at the carbonization temperature of 800°C (1.59 cm 3 /g and 931 mg/g, respectively). The obtained results showed that an increase in the specific surface area of the adsorbent did not necessarily enhance the adsorption performance. However, compared with the specific surface area of the adsorbent, its adsorption performance is improved in the case of larger pore structures. Therefore, the pore structure of the adsorbent has a very important influence on the adsorption performance. The results of kinetic and thermodynamic studies showed that the pseudo-second-order model could better explain the adsorption process of ZDPC on phenanthrene, while the intra-particle diffusion model revealed that the adsorption mechanism represented a continuous three-stage process.
研究领域:
材料科学
·
环境科学
✓ 已验证
DOI
高影响因子
MACROMOLECULAR MATERIALS AND ENGINEERING
·
2020
·Vol. 306
·期 1
·2000509
·
IF 3.853
Bo Mu,Jianbing Cui,Baoping Yang,Jinfeng Cui,Junhong Guo,Li Tian
In this work, polyurethane (PU) materials containing paraffin oil are successfully prepared via an emulsion template method, which realizes the one-pot preparation of self-lubrication materials. The results show that the block copolymer surfactant (PEG 20 -PPG 70 -PEG 20 , P-123) can stabilize the nonaqueous PU emulsion with the paraffin oil serving both as dispersed phase of oil in oil emulsion and as a lubricant in the materials, and hence enables the fabrication of oil incorporating PU materials accordingly. Tribological tests show that the friction coefficient of PU material with 35% paraffin oil decreases to 0.05 which account for 93.06% reduce compared to that of pure PU.
研究领域:
材料科学
·
摩擦学
✓ 已验证
DOI
高影响因子
Nanomaterials
·
2019
·Vol. 9
·期 6
·840
·
IF 4.034
Xianghua Zhang,Jiangtao Wang,Hongxiang Xu,Heng Tan,Xia Ye
This paper presents the facile synthesis of two different morphologies of WS2nanomaterials—WS2hexagonal nanoplates and nanoflowers—by a sulfurization reaction. The phases and morphology of the samples were investigated by X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). The tribological performance of the two kinds of WS2nanomaterials as additives in paraffin oil were measured using a UMT (Universal Mechanical Tester)-2 tribotester. The results demonstrated that the friction and wear performance of paraffin oil can be greatly improved with the addition of WS2nanomaterials, and that the morphology and content of WS2nanomaterials have a significant effect on the tribological properties of paraffin oil. The tribological performance of lubricating oil was best when the concentration of the WS2nanomaterial additive was 0.5 wt %. Moreover, the paraffin oil with added WS2nanoflowers exhibited better tribological properties than paraffin oil with added WS2hexagonal nanoplates. The superior tribological properties of WS2nanoflowers can be attributed to their special morphology, which contributes to the formation of a uniform tribo-film during the sliding process.
研究领域:
材料科学
·
摩擦学
✓ 已验证
DOI
高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2018
·Vol. 25
·期 22
·21693-21700
·
IF 2.8
Luan Ling-Yu,Zhang Li,Wang Li-Hong
Synthesized organobentonite (SOB), montmorillonite (MMT), and commercial organobentonite (COB) were used as adsorbents for paraffin oil, a model pollutant in land-based oil spills and oil pipeline rupture. The characterization of clays was carried out with scanning electron microscopy (SEM), thermogravimetric analysis (TG), Fourier transform infrared spectroscopy (FTIR), and X-ray diffraction (XRD). After adsorption, oil was separated from adsorbents with a carbon dioxide responsive solvent N,N-dimethylcyclohexylamine (DMCHA), and DMCHA was subsequently separated from paraffin oil upon CO 2 bubbling instead of distillation with high energy cost. The adsorption capacity of oil to SOB, MMT, and COB was 0.686, 1.124, and 1.239 g/g, respectively. It was found that the adsorption capacity and rinsed amount of the adsorbents depended on the d-spacing, which is related to surfactant content. Electrical conductivity and pH measurements suggested that the separation process occurred via two steps. Firstly, during the initial 35 min, carbonate ions coexisted with bicarbonate ions. Then, only bicarbonate ions existed after the introduction of CO 2 gas for 120 min. Thus, organobentonites were feasible for hydrocarbon adsorption and could be simply reused by an amine-based responsive solvent. This work provided a cost-effective and sustainable method of recycling of organobentonites and the responsive solvent, which can be used to deal with leaked oil and oil spills.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Materials Research Express
·
2017
·Vol. 4
·期 11
·115011
·
IF 1.068
Xianghua Zhang,Yaping Xue,Xia Ye,Hongxiang Xu,Maoquan Xue
In this work, ultrathin MoS2 nanosheets were prepared via a solid-state reaction route. The structure and morphology of the obtained samples were characterized by x-ray diffraction, transmission electron microscopy and scanning electron microscopy. The influences of the reaction durations and raw materials molar ratio on the sizes and morphologies of the MoS2 nanostructures were discussed. And according to the experimental results, a formation mechanism of the ultrathin MoS2 nanosheets was proposed. The tribological behaviors of the synthesized MoS2 samples as additives in paraffin oil were determined on an UMT-2 tribometer. The experimental results indicated that the obtained samples possessed great anti-friction and anti-wear properties as lubrication additive in paraffin oil.
研究领域:
材料科学
·
纳米技术
·
摩擦学
✓ 已验证
产品关联
DOI
高影响因子
Cells
·
2019
·Vol. 8
·期 8
·892
·
IF 5.656
Dattatrya Shetti,Bao Zhang,Conghui Fan,Canlong Mo,Bae Hoon Lee,Kun Wei
Triple-negative breast cancer (TNBC) accounts for 15% of overall breast cancer. A lack of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2 receptor) makes TNBC more aggressive and metastatic. Wnt signaling is one of the important pathways in the cellular process; in TNBC it is aberrantly regulated, which leads to the progression and metastasis. In this study, we designed a therapeutic strategy using a combination of a low dose of paclitaxel and a Wnt signaling inhibitor (XAV939), and examined the effect of the paclitaxel-combined XAV939 treatment on diverse breast cancer lines including TNBC cell lines (MDA-MB-231, MDA-MB-468, and BT549) and ER+ve cell lines (MCF-7 and T-47D). The combination treatment of paclitaxel (20 nM) and XAV939 (10 µM) exerted a comparable therapeutic effect on MDA-MB-231, MDA-MB-468, BT549, MCF-7, and T-47D cell lines, relative to paclitaxel with a high dose (200 nM). The paclitaxel-combined XAV939 treatment induced apoptosis by suppressing Bcl-2 and by increasing the cleavage of caspases-3 and PARP. In addition, the in vivo results of the paclitaxel-combined XAV939 treatment in a mice model with the MDA-MB-231 xenograft further confirmed its therapeutic effect. Furthermore, the paclitaxel-combined XAV939 treatment reduced the expression of β-catenin, a key molecule in the Wnt pathway, which led to suppression of the expression of epithelial-mesenchymal transition (EMT) markers and angiogenic proteins both at mRNA and protein levels. The expression level of E-cadherin was raised, which potentially indicates the inhibition of EMT. Importantly, the breast tumor induced by pristane was significantly reduced by the paclitaxel-combined XAV939 treatment. Overall, the paclitaxel-combined XAV939 regimen was found to induce apoptosis and to inhibit Wnt signaling, resulting in the suppression of EMT and angiogenesis. For the first time, we report that our combination approach using a low dose of paclitaxel and XAV939 could be conducive to treating TNBC and an external carcinogen-induced breast cancer.Keywords:breast cancer;XAV939;apoptosis;EMT;pristane;angiogenesis;combination treatment;Wnt signaling
研究领域:
肿瘤学
·
药理学
·
细胞生物学
·
癌症研究
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MATERIALS SCIENCE FORUM
·
2022
·
IF 0
Mohd Khairul Nizam,Mohamad Shafiq Mohd Razmi,Najmuddin Mohd Ramli,Mohd Najib Razali
Three formulations intended for NSF H1 food-grade grease were prepared in this study comprising paraffin oil as a base oil and fumed silica as a thickener. No additive was added in formulation 1 (F1) and formulation 2 (F2), whereas chitosan was added in formulation 3 (F3) as an additive. A commercial food-grade grease (FGG) was used for comparison purposes. The formulated greases and the commercial FGG were characterised for thermal stability via thermogravimetric analysis (TGA) and derivative thermogravimetric analysis (DTG). Fourier-transform infrared (FTIR) spectroscopy, dropping point, oil separation, and consistency tests were also carried out to evaluate the properties of the greases. The FTIR spectra were obtained for the fresh and aged greases for grease characterisation. The results showed that the grease made with chitosan as an additive demonstrated higher oil separation, better consistency, and was less affected by ageing, as indicated by the change of grease colour after the oil separation test. F1, F2, F3, and the commercial FGG recorded dropping points higher than 350 °C, indicating no dropping point properties for the tested greases. The grease formulated with chitosan (F3) achieved the highest oil separation with 1.21%, while the commercial FGG recorded the lowest oil separation with 0.66%, followed by F1 and F3 with the oil separation of 0.99% and 0.98%, respectively. For the consistency test, the NLGI number for each formulation varied but the commercial FGG showed the lowest NLGI number of 2, whereas F3 showed the NLGI number in the range of 2–3, and F1 showed the NLGI number of 3. The aged grease of F3 had unchanged consistency after the oil separation test. Based on the results, the formulated greases have acceptable properties in comparison to the commercial FGG, and the addition of chitosan contributes positively to the grease characteristics.
研究领域:
材料科学
·
食品技术
·
润滑工程
✓ 已验证
DOI
POLYCYCLIC AROMATIC COMPOUNDS
·
2021
·
IF 3.744
Rui Yan,Xiaoliu Huang,Xianqing Deng,Mingxia Song
In this study, 18 pyrazole derivatives coupled with pyrazoline were synthesized and screened for their anti-inflammatory and antimicrobial activities. All the target compounds were synthesized smoothly and characterized using 1H NMR, 13C NMR, and HRMS. In vitro lipopolysaccharide (LPS)-induced tumor necrosis factor (TNF)-α model and in vivo xylene-induced ear-edema model were used to evaluate their anti-inflammatory activity. Antimicrobial activity against several Gram-positive strains and Gram-negative strains was evaluated using a serial dilution method. Pharmacological results indicated that most of the compounds markedly inhibited the expression of TNF-α at the concentration of 20 μg/mL. Compounds 9b showed 66.4% inhibition for the LPS-induced TNF-α release, which was superior than that of the positive control drug dexamethasone (DXMS). And compounds 4a, 4b, 5a, 5b, 6b, and 9b showed comparable inhibition activity to DXMS. In xylene-induced ear-edema model, compound 4a inhibited edema by 48.71%, which was more effective than DXMS (47.18%) in inhibiting xylene-induced ear edema. Compound 4b, 5a, 5b, 6b, and 9b showed inhibition of 36.82%, 27.65%, 45.87%, 31.78%, and 43.67%, respectively. Furthermore, compounds 4a, 5a, 5b, and 9b displayed broad-spectrum antimicrobial activity against several Gram-positive and Gram-negative bacterial. These compounds, 4a, 5a, 5b, and 9b, possess both anti-inflammatory and antimicrobial activities, thus are worth further investigation to enhance their antimicrobial activities for the development of new class of dual anti-inflammatory–antimicrobial agents.
研究领域:
药理学
·
药物化学
·
微生物学
✓ 已验证
DOI
高影响因子
INTERNATIONAL JOURNAL OF PHARMACEUTICS
·
2024
·
IF 5.3
Ben Chen,Dingwei Li,Bingjie Tong,Lifen Wang,Haoran Lin,Helin Xu,Sunkuan Hu
Ulcerative colitis (UC) is a chronic bowel inflammatory disease affecting the colorectum. Epidermal growth factor (EGF) has been demonstrated to be effective to counteract UC. However, there exists the gastrointestinal challenges such as stomach acid, enzyme and bile salts for oral delivery of EGF. Herein, calcium alginate microsphere was prepared by the microfluidic technique to encapsulate EGF. The morphology of EGF-loaded microsphere (MS-EGF) was spherical and its average particle size was 80 ± 23 μm. The encapsulation efficiency of EGF was reaching to 93.8 % ± 1.6 %. In vitro release experiments showed that MS-EGF presented the good pH-sensitive properties, that was, it could effectively resist the gastric acid and small intestinal fluids, and undergone the rapid dissolution in the artificial colon fluid. In vitro cellular experiments demonstrated that the bioactivity of EGF was well preserved by microsphere. Moreover, in vivo murine colitis model showed that MS-EGF presented the obvious colitis alleviation. Furthermore, the colonic morphology of colitis mice was effectively recovered and the tight junction between the gut epithelium was obviously repaired. In conclusion, calcium alginate microsphere might be a promising vehicle of EGF for UC treatment.
研究领域:
药学
·
胃肠病学
·
药物递送系统
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CARBON
·
2024
·
IF 10.5
Xiaoqi Mao,Longlong Dong,Yiya Zhang,Shuanglin Qin,Guodong Sun,Lianwen Wang,Yusheng Zhang
Synergistic improvement of strength and ductility is challenging in the engineering applications of titanium matrix composites (TMCs). Herein, we fabricated the TC4 composites reinforced with grain boundary micron-TiC and intragranular nano-Ti 2 Cu using spark plasma sintering (SPS) and hot rolling (HR) to achieve a good balance between strength and ductility. An interfacial reaction between Ti and C forms the grain boundary TiC, and the vast majority of intragranular nano-Ti 2 Cu precipitates to accommodate the severe lattice distortion caused by the solid solution of Cu in β-Ti phase. Benefiting from Ti 2 Cu nanoprecipitates and their ability to effectively suppress dislocation motion , precipitation strengthening, and dislocation strengthening are the main factors, in addition to grain refinement strengthening due to deformation processing , that contribute to the realization of the superior yield strength (YS) of 1360 MPa and ultimate tensile strength (UTS) of 1504 MPa in composites than TC4 matrix (YS = 986 MPa, UTS = 1160 MPa). Meanwhile, the interfacial strain-delocalization effect of TiC/Ti 2 Cu with Ti matrix, the shear-lag effect of TiC, and the sustained strain-hardening effect provided by TiC/Ti 2 Cu empower the composites with an outstanding ductility (fracture elongation of 8.4 %). This study highlights the untapped potential for improving the mechanical properties of Ti matrix composites.
研究领域:
材料科学
·
力学工程
✓ 已验证
产品关联
DOI
高影响因子
Frontiers in Physiology
·
2025
·
IF 3.4
Yue Qin Song,Tian Si Zhang,Hao Zhan Yuan,Sheng Jie Han,Bo Liao Li
Athetis dissimilis is one of the main pests affecting crops, and is currently managed through chemical control methods. Plant volatiles can stimulate insects to feed and lay eggs. The investigation of plant volatiles and the development of effective attractants are essential for sustainable pest control. In this study, we examined plant volatiles using electroantennogram (EAG) analysis, and observed alterations in OBP expression in A. dissimilis . The EAG results indicated that the EAG responses for trans -2-hexenal, cis -3-hexen-1-ol, and trans -2-hexen-1-ol in male adults were the highest, measuring 1.35 ± 0.02 mV, 1.30 ± 0.10 mV and 1.27 ± 0.18 mV, respectively. This was followed by ( E , E )-2,4-hexadienal (1.01 ± 0.06 mV), octanal (0.69 ± 0.04 mV), hexanal (0.67 ± 0.04 mV), benzothiazole (0.64 ± 0.01 mV), and benzyl acetate (0.61 ± 0.02 mV). The EAG responses of male adults towards the ligands above were generally higher than those of female adults. After fumigation, the expression levels of AdisOBPs in both female and male antennae exhibited varying degrees of increase compared with non-fumigated antennae. The expression levels of AdisOBP9 and AdisOBP11 in female antennae were significantly higher than those in the paraffin control after fumigation with β-caryophyllene. In addition, after fumigation by β-caryophyllene, the expression levels of AdisOBP9 , AdisOBP11 , AdisOBP24 and AdisOBP21 in male antennae increased significantly compared with those in the paraffin control. Similarly, after fumigation with benzyl acetate, the expression levels of AdisOBP9 , AdisOBP11 , AdisOBP24 , AdisOBP21 , AdisOBP7 , AdisOBP4 and AdisOBP50 in male antennae were significantly elevated compared with those in the paraffin control. The number of upregulated genes was greater in male adults than in female adults, which aligns with the results of the EAG test. That is to say, male adults exhibited a stronger response to odor stimulation than female adults. Our findings provide valuable insights into the olfactory mechanisms of insects and contribute to the development of new environmentally friendly pest control methods.
研究领域:
昆虫学
·
害虫治理
·
植物与昆虫互作
·
分子生物学
·
化学生态学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2024
·
IF 8.1
Shuoshuo Song,Changjun Li,Wenlong Jia,Nobuo Maeda,Xuehua Zhang,Huan Xiao,Fan Yang,Yuanrui Zhang
Formation of emulsions containing asphaltenes is both undesirable and unavoidable in petroleum production. Chemical demulsifiers, such as non-ionic surfactants, have long been applied as the cheapest and most effective method of breaking emulsions by altering the oil/water interfacial properties. In this study, the association state of the asphaltenes, the dehydration rate, and the interfacial rheology under various demulsifier concentrations were used to analyze the contributions of non-ionic demulsifiers to the breaking of the asphaltene-containing emulsions. Additionally, the dynamic interfacial tension (DIFT) data over time were used to investigate the adsorption kinetics of the asphaltenes and the demulsifier at the oil/water interface. Results indicate that liquid paraffin enhanced the association of the asphaltene molecules, while the non-ionic demulsifier rendered asphaltene aggregate sizes smaller. The addition of the demulsifiers reduced the interfacial strength, leading to an unstable interface. The oil-soluble demulsifiers reduced IFT more effectively than the water-soluble ones, due to their faster migration rate and low interfacial tension gradient to the oil–water interface. The adsorption process of the asphaltenes, influenced by the demulsifier concentration, could be divided into three stages: a short-term diffusion-controlled process, a transition process, and a slow descent process (referred to as Regimes I, II, and III). In Regime I, the diffusion coefficient of asphaltenes increased with the demulsifier concentration, indicating that the demulsifier aided the dispersing of the asphaltenes in the solution. The equilibrium IFT and the maximum surface excess concentration of the asphaltenes in the long-term adsorption process decreased with the demulsifier concentration, indicating that the asphaltene-containing emulsions generally became unstable after adding the demulsifiers. Our results offer valuable insights into the adsorption kinetics and the mechanisms of alterations by the asphaltenes and demulsifiers of the oil/water interface, with implications for various interfacial phenomena (e.g., emulsion stability) involving surfactants in oil production, transportation, and processing.
研究领域:
石油工程
·
界面化学
·
胶体科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）