In this study, a highly perm-selective thin-film composite (TFC) nanofilm was successfully developed via silicification interlayer-mediated interfacial polymerization. The silicification interlayer, fabricated in situ, significantly improved the surface hydrophilicity of the polysulfone (PSf) substrate and facilitated the high-density uptake of amine monomers. The interlayer also served as a quasi-molecular-scale regulator that decelerated the diffusion of amine monomers into the organic phase to polymerize with the acyl chloride of 1,3,5-benzenetricarbonyl trichloride (TMC). The synergistic effects triggered self-sealing and inhibited the membrane growth, which promoted the formation of ultrathin polyamide (PA) nanofilms (approx. 13 nm) with enhanced crosslinking properties. The best-performing PA_SiO2/PSf membrane exhibited a high water permeance of 14.5 L m−2 h−1 bar−1, which was approximately three times the permeance of the pristine PA membrane (4.8 L m−2 h−1 bar−1). Furthermore, the membrane exhibited a high rejection capability toward divalent salts (98.7% against Na2SO4) and mono/divalent ion selectivity of 60.9. Hence, the newly developed PA_SiO2/PSf membrane exhibits competitive separation properties compared to the state-of-the-art desalination membranes. The technique is applicable to the majority of conventional interfacial polymerizations, which highlights its use in the development of high-performance membranes for water remediation.
Jie Hou,Huichang Gao,Yingjun Wang,Delin Cheng,Xiaodong Cao
Modifying substrates through mineralization is a popular way to improve the osteogenic performance. Screening of the best mineralization characteristics on specific substrates for stem cells is meaningful but not fully studied. In this paper, poly(lactic-co-glycolic acid)/hydroxyapatite (PLGA/HA, PH) microsphere scaffolds with superficial pores were fabricated by a low-temperature fusion method. After the mineralization in the 5× stimulated body fluid (SBF) for 0, 7, 12 and 24 h, four mineralized scaffolds (MPH-0, MPH-7, MPH-12 and MPH-24) with different apatite topographies were obtained. It was found that the surface of MPH-7 was evenly decorated with abundant micro-pores, MPH-12 with dense and plain apatite layer, and MPH-24 with small spherical bumps. The responses of mouse bone mesenchymal stem cells (mBMSCs) to the four scaffolds were further studied. The results showed that MPH-7 and MPH-24 had more obvious effects on mBMSCs attachment, proliferation and differentiation than MPH-0 and MPH-12. This work indicated that to obtain the maximum improvement, the mineralization characteristics had to be carefully chosen. This was noteworthy in the chemical modification of surfaces to form the functionalized scaffolds for bone repair.
危险品化学品经营许可证（带存储）