PROCESS SAFETY AND ENVIRONMENTAL PROTECTION
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2016
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IF 2.078
Shungang Wan,Zulin Hua,Lei Sun,Xue Bai,Lu Liang
This investigation emphasized the optimum preparation conditions for the chemical modification of eucalyptus sawdust biochar as a potential biosorbent to promote the removal of nitroimidazoles from aqueous solutions. By ANOVA for central composite design of response surface methodology, we found the activation temperature and impregnation ratio of 85% H 3 PO 4 to sawdust as the significant factors for maximizing the adsorption capacity of metronidazole. Optimum activation temperature, impregnation ratio, and activation time were 500 °C, 0.62, and 90 min, respectively. The Brunauer–Emmett–Teller surface area and total pore volume increased from 32.80 m 2 g −1 to 882.04 m 2 g −1 and 0.01829 cm 3 g −1 to 0.4316 cm 3 g −1 after H 3 PO 4 activation, respectively. The removal efficiencies using biochar prepared at optimum conditions were 97.1% and 96.4% for metronidazole and dimetridazole at 20 mg L −1 concentration and 1.0 g L −1 biochar dosage within 2 h. The adsorption process was described well by pseudo-second-order model, and solute transfer was controlled by both boundary-layer and intraparticle diffusion. Thermodynamic study revealed that the adsorption process was spontaneous and exothermic. The Freundlich model presented better a fit for the adsorption equilibrium. The maximum adsorption capacities for metronidazole and dimetridazole were 167.5 and 200 mg g −1 , respectively.
研究领域:
环境科学
·
生物学
✓ 已验证
DOI
高影响因子
JOURNAL OF SOLID STATE CHEMISTRY
·
2024
·
IF 3.2
Le Chen,An Xie,Nan Zhang,Jianjun Yin,Qun Chen,Mingyang He,Zhihui Zhang
Zeolitic-Imidazolate Framework 8 (ZIF-8), a porous crystalline absorbent, could be synthesized from the coordination reaction of zinc ions and 2-methylimidazole (2-mIM). ZIF-8 has a large specific surface area and a high adsorption capacity for n -hexane ( n HEX). However, ZIF-8 suffers from low selectivity for both linear and mono-chain alkanes. Therefore, ZIF-8 was modified through 2-mIM ligand being partly replaced by 2-nitroimidazole (2-nIM) through Vapor-Phase post-synthesis modification. The modified materials were denoted as ZIF-8-2-nIM-X (X = 24h, 48h, 72h). ZIF-8-2-nIM-X has a higher specific surface area and better thermal stability than ZIF-8. Further thermodynamic and kinetic calculations show that the affinity of hexane isomers on ZIF-8-2-nIM-X is spontaneous physical adsorption combined with an exothermic process. In contrast, kinetic studies show that the adsorption of hexane isomers on ZIF-8-2-nIM-X is a pseudo-second-order kinetic model. The batch and dynamic adsorption and separation properties of ZIF-8-2-nIM-X for hexane isomers were studied. The results of the one-component vapor adsorption equilibrium experiment show that ZIF-8-2-nIM-72h has the best adsorption separation coefficient at 293 K. The adsorption capacity of n HEX and 3-methylpentane (3MP) were 211.63 mg/g and 33.91 mg/g, respectively. Compared with ZIF-8 (selectivity coefficient: 1.08), the adsorption selectivity coefficient of the modified material is greatly improved. The adsorption selectivity coefficient of n HEX/3MP is 6.24 (ZIF-8-2-nIM-72h).
研究领域:
材料科学
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物理化学
✓ 已验证
产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Zixuan Zhou,Yuhan Jiang,Xin Luo,Ying Zhang,Lei Wang,Yaguang Sun,Mingchang Zhu,Shuangyan Wu
The development of efficient, rapid, portable, and accurate analysis methods for detecting veterinary antibiotic residues in water matrices is highly demanded for environmental safety assessment. In this study, we have developed a sensor array (Cd-phen-PEDA) for the discrimination of various nitroimidazole antibiotics (NIIMs). The Cd-phen-PEDA sensor array exhibits high selectivity and sensitivity for the detection of metronidazole (MNZ), ornidazole (ONZ), and dimetridazole (DMZ). The limit of detection (LOD) for each antibiotic is 6.18 μM for MNZ, 4.80 μM for ONZ, and 5.40 μM for DMZ. The detection application of the Cd-phen-PEDA sensor array for nitroimidazole antibiotics (NIIMs) was successfully extended to real environmental samples. This demonstrates the practical applicability and reliability of the sensor in real-world scenarios, further enhancing its potential for environmental safety assessment. The Linear Discriminant Analysis (LDA) and hierarchical cluster analysis (HCA) results confirm the effectiveness of the Cd-phen-PEDA-based luminescent array in simultaneously identifying and detecting nitroimidazole antibiotics (NIIMs) in environmental samples. This dual analytical approach not only enhances the accuracy of detection but also provides a robust method for the discrimination and quantification of these antibiotics across various environmental matrices.
研究领域:
分析化学
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环境科学
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药学
✓ 已验证
产品关联
DOI
高影响因子
NANO
·
2020
·
IF 1.566
Heng Chen,Mengbing Cui,Cuilan Miao,Gairong Chen,Yongchun Zhang
In this work, the function of 4-nitroimidazole (4-NIm) in the formation of Cr-MIL-101 was confirmed. It was found that 4-NIm is an effective additive in the formation of Cr-MIL-101 synthesized at lower temperature. The investigation of crystallization time showed that 4-NIm can prevent Cr-MIL-101 phase converting into Cr-MIL-53 phase. The effect of concentration of 4-NIm on the morphology and the yield of Cr-MIL-101 may therefore be explained by increasing the nucleation rate. The investigation of crystallization temperature revealed that 4-NIm changes the synthesis temperature range of Cr-MIL-101 into 423–463 K. The assistant function of 4-NIm was played through interaction with H + and NO 3 − in the synthesis system, which may lead to enhancement of the deprotonation of H 2 BDC.
研究领域:
材料化学
·
配位化学
✓ 已验证
产品关联
DOI
高影响因子
Journal of Environmental Sciences
·
2019
·
IF 3.556
Wanyue Liu,Mingjing Ke,Zhenyan Zhang,Tao Lu,Youchao Zhu,Yan Li,Xiangliang Pan,Haifeng Qian
Imazethapyr (IM) is an acetolactate synthase (ALS)-inhibiting herbicide that has been widely used in recent years. However, IM spraying can lead to the accumulation of herbicide residues in leaves. Here, we determined the effects of IM spraying on the plant growth and leaf surface microbial communities of Arabidopsis thaliana after 7 and 14 days of exposure. The results suggested that IM spraying inhibited plant growth. Fresh weight decreased to 48% and 26% of the control value after 7 and 14 days, respectively, of 0.035 kg/ha IM exposure. In addition, anthocyanin content increased 9.2-fold and 37.2-fold relative to the control content after 7 and 14 days of treatment, respectively. Furthermore, IM spraying destroyed the cell structures of the leaves, as evidenced by increases in the number of starch granules and the stomatal closure rate. Reductions in photosynthetic efficiency and antioxidant enzyme activity were observed after IM spraying, especially after 14 days of exposure. The diversity and evenness of the leaf microbiota were not affected by IM treatment, but the composition of community structure at the genus level was altered by IM spraying. Imazethapyr application increased the abundance of Pseudomonas , a genus that includes species pathogenic to plants and humans, indicating that IM potentially increased the abundance of pathogenic bacteria on leaves. Our findings increase our understanding of the relationships between herbicide application and the microbial community structures on plant leaves, and they provide a new perspective for studying the ecological safety of herbicide usage.
研究领域:
植物学
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生态学
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环境科学
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF CHROMATOGRAPHY A
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2013
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IF 4.612
Xiupei Yang,Xiumei Cheng,Yingyun Lin,Zhijing Tan,Linxiang Xie,Martin M.F. Choi
This study reports a sweeping and micelle to solvent stacking (MSS) method for fast stacking of nitroimidazoles in capillary zone electrophoresis (CZE). The optimal experimental conditions are run buffer of 25 mM sodium phosphate (pH 1.5) and 0.50% (v/v) methanol, micellar solution of 30 mM sodium dodecyl sulfate, applied voltage of 28 kV, and sample and micellar solution injection of 100 s. By applying this new on-line preconcentration technique, the nitroimidazoles content can be determined within 9 min with the limit of detection ( S / N = 3) ranging 2.3–3.0 ng/mL, which is lower than that of conventional CZE analysis. The proposed MSS technique affords 20-, 12- and 38-fold improvements in sensitivity for the detection of dimetridazole, metronidazole and secnidazole, respectively. The relative standard deviations (RSDs) of intra-day and inter-day are 2.1–3.6% and 2.7–4.6% ( n = 6), respectively. The recoveries in pretreated rabbit plasma at spiked levels of 5.0–10.0 μg/mL are 92.0–101.1% with RSDs lower than 3.4%. The proposed sweeping and MSS-CZE is a highly sensitive method for the detection of nitroimidazoles in biological and clinical samples and has been successfully applied to analyze nitroimidazoles in pretreated rabbit plasma.
研究领域:
分析化学
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药物分析
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临床医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2022
·
IF 4.601
Yang Wang,Hongwei Yuan,Ye Wan,Lei Zhang
Herein, a magnetic three-dimensional acanthosphere-like hierarchical Co@graphitic carbon (3D Co@GC) is introduced as an efficient adsorbent for extraction of three nitroimidazoles (NMZs: metronidazole (MNZ), ornidazole (ONZ) and tinidazole (TNZ)) from environmental water and food samples. The proposed 3D Co@GC was synthesized by a simple template-free method, which consisted of plentiful freely arranged one-dimensional nanowires. The adsorption properties of 3D Co@GC for three NMZs were investigated systematically by adsorption kinetic and isotherm studies. 3D Co@GC exhibits good adsorption capacity and fast adsorption kinetics toward three NMZs by virtue of its unique hierarchical structure. In addition, it was also found that a bit of methanol can effectively elute the adsorbed NMZs, eliminating the need for other dangerous strong acid or base solutions. Thus, 3D Co@GC as adsorbent to extraction three trace NMZs followed by direct quantification detection of targets with high-performance liquid chromatography with ultraviolet–visible detector (HPLC-UV) was developed. The parameters of dispersed magnetic solid-phase extraction (d-MSPE) were optimized by univariate and multivariate methods (Box-Behnken design). This established method revealed wide linear range and low limits of detection. Furthermore, the satisfactory recoveries of NMZs (86.7–106.7%) were acquired in spiked river water, honey, milk, and muscle samples. This study might provide a potential strategy for the efficient extraction and sensitive analysis of trace NMZs in river water, honey, milk, and muscle samples.
研究领域:
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ELECTROPHORESIS
·
2022
·
IF 3.595
Jing Yang,Lianfang Chen,Qingying Wang,Xiaolin Mei,Xiupei Yang,Feng Huo
For a long time, the detection of nitroimidazole antibiotics (NIABs) has been a research focus in environmental analytical chemistry. In this work, a novel technique for the analysis of nitroimidazoles was established based on capillary electrophoresis (CE). UiO-66, synthesized using a solvothermal method, was utilized as an adsorbent in the dispersive solid-phase extraction (DSPE) of five different NIABs. The separation and detection of NIABs in environmental water samples were accomplished using the CE diode array detection method. The optimal extraction conditions were obtained after systematically studying the effects of adsorption time, the amount of extractant, and elution solvent on extraction efficiency. According to the results of the study, the limit of detections of the five NIABs were between 16 and 97 ng/mL, the relative standard deviations were between 0.32% and 0.55%, and the spike recoveries were between 87.43% and 104.8%. This study presents a novel technique for measuring NIABs in complex water samples.
研究领域:
环境分析化学
·
药物分析
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Food Chemistry-X
·
2025
·
IF 8.2
Mengdie Cai,Xinyu Wang,Kun Lu,Bixiao Zhou,Lijun Wei,Xianglei Cheng
Residues of nitro-containing drugs in food and the environment have aroused social concern because of their excessive use for the treatment of human and animal diseases. The disadvantages of complex and time-consuming pretreatments in existing methods make it imperative to develop novel methods. Herein, with the aid of recognition probe MCLA, an excellent selective method for the detection of nitroimidazoles (NDZs) was developed based on high-performance liquid chromatography combined with ultraviolet (UV) degradation and chemiluminescence (HPLC-UV-CL). The study proposed an innovative process for the formation of SO 4 •− , •OH, and •NO via advanced oxidation processes of NDZs. Six studied NDZs achieved baseline separation within 24 min with detection limits as low as 3 ng/mL (S/N = 3 ). The proposed method is efficient, cost-effective, and does not require complicated purification steps. This study presents a unique approach for the detection of nitro-containing contaminants and provides new insights into monitoring advanced oxidation processes.
研究领域:
分析化学
·
食品安全
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICA CHIMICA ACTA
·
2016
·
IF 4.712
Na Xu,Hong-Wei Li,Yuqing Wu
A novel one-step hydrothermal synthesis of highly fluorescent platinum nanoclusters protected by polyethylenimine (Pt-NCs@PEI) is described. The products are characterized well by UV–vis absorption, fluorescence spectra , X-ray photoelectron spectroscopy (XPS) and transmission electron microscopy (TEM) imaging. The Pt-NCs@PEI possess high quantum yield at 28%, which is the relatively high one among the reported Pt-NCs; especially, the synthesis is in one-step and the reaction time is much shorter (<1 h) than the related methods. In addition, the Pt-NCs@PEI have large Stocks-shift (∼150 nm), high tolerability to the extreme pH and high ionic strengths , and excellent photo-stability under UV–vis irradiation, lay the foundation for the practical bio-applications. Finally, the obtained Pt-NCs@PEI are used to determine trace amount of metronidazole (MTZ) in buffer solution in showing a linear response over a concentration range of 0.25–300 μM and a low detection limit of 0.1 μM. Furthermore, the related investigation on response mechanism will be helpful to design and synthesize new metal nanoclusters as fluorescent probe to detect the trace amount of harmful medicine residuum as nitroimidazoles in human body.
研究领域:
分析化学
·
纳米材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Food Bioscience
·
2022
·
IF 5.318
Siqian Shi,Hang Yu,Fangwei Yang,Weirong Yao,Yunfei Xie
Nitroimidazoles are a family of veterinary drugs containing a 5-nitroimidazole ring structure, which are commonly used antibiotics. In view of their potential genotoxicity and possible coexistence in actual samples, it is necessary to establish a rapid and effective method for the simultaneous determination of multiple nitroimidazoles. In this study, a rapid thin-layer chromatography combined with surface-enhanced Raman spectroscopy (TLC-SER) detection method for 14 nitroimidazole compounds has been established. The theoretical Raman spectra of the nitroimidazoles were calculated using the B3LYP/6-311+G(d) basis set in density functional theory (DFT) and the theoretical Raman spectra of TNZ , NBZ, ONZ , SCZ, DMZ , MNI, 2-HMZ, 4-HMZ, CMNI, IPZ , MNZ-OH and HMDMZ have been obtained for the first time. SERS detection was carried out on a gold nanoparticles (AuNPs) substrate, which exhibited strong SERS signals and a limit of detection limit of 0.1 mg/L. By optimizing the conditions used for the developing agent in TLC, 12 nitroimidazoles were successfully separated, while MNZ and RNZ still could not be separated. When combined with the chemometrics analysis method, the TLC-SERS method can realize the simultaneous detection of 14 nitroimidazoles. Actual pork samples were spiked with nitroimidazoles with a recovery rate of 80%–110% and RSD of 0.74%–16.70%, which showed that SERS and TLC-SERS methods are also effective for detection in actual samples. The detection time of this method is < 10 min, which is suitable for the rapid detection of nitroimidazoles, especially for the rapid qualitative identification of nitroimidazoles in situ.
研究领域:
分析化学
·
兽医学
·
食品安全
✓ 已验证
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Shuofeng Li,Qianqian Wang,Yixuanfei Gao,Yihang He,Zhi Wang,Chun Wang,Qiuhua Wu
Herein, a novel chitosan based hyper crosslinked polymer (Chi-gs-BDCB) was synthesized as sorbent by crosslinking reaction with biphenyl dichlorobenzyl as crosslinking agent after grafting chitosan with styrene. Benefiting from large specific surface area, affluent hydroxyl-functional groups, high porosity and good hydrophilicity, Chi-gs-BDCB displayed good adsorption properties for nitroimidazole antibiotics. Applying Chi-gs-BDCB as solid-phase extraction sorbent coupled with high performance liquid chromatography-ultraviolet detection, a sensitive and accurate analytical method for detecting nitroimidazole antibiotics in beef and mutton meat was established. Under optimal conditions and at S/N = 3, high sensitivity was obtained with the detection limits of 0.40–1.60 ng g −1 for mutton and 0.33–1.0 ng g −1 for beef. Satisfactory accuracy and precision were confirmed by the recoveries of 81.4 %–116 % and low relative standard deviations of 1.23 %–10.0 %. These data validate the feasibility and effectiveness of the chitosan-based sorbent for enriching nitroimidazole antibiotics at trace level from beef and mutton meat.
研究领域:
食品科学
·
分析化学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）